Volume 9; Issue 2

Main
ACS Chemical Biology
Volume 9; Issue 2

ACS Chemical Biology

Volume 9; Issue 2

1

A Glycosylated, Labionin-Containing Lanthipeptide with Marked Antinociceptive Activity

Iorio, Marianna, Sasso, Oscar, Maffioli, Sonia I., Bertorelli, Rosalia, Monciardini, Paolo, Sosio, Margherita, Bonezzi, Fabiola, Summa, Maria, Brunati, Cristina, Bordoni, Roberta, Corti, Giorgio, Taro

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

2

Discovery of Light-Responsive Ligands through Screening of a Light-Responsive Genetically Encoded Library

Jafari, Mohammad R., Deng, Lu, Kitov, Pavel I., Ng, Simon, Matochko, Wadim L., Tjhung, Katrina F., Zeberoff, Anthony, Elias, Anastasia, Klassen, John S., Derda, Ratmir

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

3

Design and Kinetic Analysis of a Hybrid Promoter–Regulator System for Malonyl-CoA Sensing in Escherichia coli

Xu, Peng, Wang, Wenya, Li, Lingyun, Bhan, Namita, Zhang, Fuming, Koffas, Mattheos A. G.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

4

Biosynthesis of Ambiguine Indole Alkaloids in Cyanobacterium Fischerella ambigua

Hillwig, Matthew L., Zhu, Qin, Liu, Xinyu

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

5

A Liquid Array Platform for the Multiplexed Analysis of Synthetic Molecule–Protein Interactions

Doran, Todd M., Kodadek, Thomas

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

6

Active Form of the Protein Kinase CK2 α 2 β 2 Holoenzyme Is a Strong Complex with Symmetric Architecture

Lolli, Graziano, Ranchio, Alessandro, Battistutta, Roberto

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.90 MB

english, 2014

7

Ligands for Glaucoma-Associated Myocilin Discovered by a Generic Binding Assay

Orwig, Susan D., Chi, Pamela V., Du, Yuhong, Hill, Shannon E., Cavitt, Marchello A., Suntharalingam, Amrithaa, Turnage, Katherine C., Dickey, Chad A., France, Stefan, Fu, Haian, Lieberman, Raquel L.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

8

An Insect Defensin-Derived β-Hairpin Peptide with Enhanced Antibacterial Activity

Gao, Bin, Zhu, Shunyi

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 4.45 MB

english, 2014

9

Fucose, Mannose, and β- N -Acetylglucosamine Glycopolymers Initiate the Mouse Sperm Acrosome Reaction through Convergent Signaling Pathways

Wu, Linghui, Sampson, Nicole S.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

10

Galactofuranose-Coated Gold Nanoparticles Elicit a Pro-inflammatory Response in Human Monocyte-Derived Dendritic Cells and Are Recognized by DC-SIGN

Chiodo, Fabrizio, Marradi, Marco, Park, Joohae, Ram, Arthur F. J., Penadés, Soledad, van Die, Irma, Tefsen, Boris

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 976 KB

english, 2014

11

Single-Cell and Single-Molecule Analysis Deciphers the Localization, Adhesion, and Mechanics of the Biofilm Adhesin LapA

El-Kirat-Chatel, Sofiane, Beaussart, Audrey, Boyd, Chelsea D., O’Toole, George A., Dufrêne, Yves F.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.92 MB

english, 2014

12

GSK3 Alpha and Beta Are New Functionally Relevant Targets of Tivantinib in Lung Cancer Cells

Remsing Rix, Lily L., Kuenzi, Brent M., Luo, Yunting, Remily-Wood, Elizabeth, Kinose, Fumi, Wright, Gabriela, Li, Jiannong, Koomen, John M., Haura, Eric B., Lawrence, Harshani R., Rix, Uwe

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

13

Molecular Vehicles for Mitochondrial Chemical Biology and Drug Delivery

Rin Jean, Sae, Tulumello, David V., Wisnovsky, Simon P., Lei, Eric K., Pereira, Mark P., Kelley, Shana O.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

14

The Commonly Used PI3-Kinase Probe LY294002 Is an Inhibitor of BET Bromodomains

Dittmann, Antje, Werner, Thilo, Chung, Chun-Wa, Savitski, Mikhail M., Fälth Savitski, Maria, Grandi, Paola, Hopf, Carsten, Lindon, Matthew, Neubauer, Gitte, Prinjha, Rabinder K., Bantscheff, Marcus, D

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

15

Profiling Substrates of Protein Arginine N -Methyltransferase 3 with S -Adenosyl- l -methionine Analogues

Guo, Han, Wang, Rui, Zheng, Weihong, Chen, Yuling, Blum, Gil, Deng, Haiteng, Luo, Minkui

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

16

Traceless Labeling of Glycoproteins and Its Application to the Study of Glycoprotein–Protein Interactions

Yang, Yung-Lin, Lee, Yen-Pin, Yang, Yen-Ling, Lin, Po-Chiao

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

17

Allosteric Regulation of Epoxide Opening Cascades by a Pair of Epoxide Hydrolases in Monensin Biosynthesis

Minami, Atsushi, Ose, Toyoyuki, Sato, Kyohei, Oikawa, Azusa, Kuroki, Kimiko, Maenaka, Katsumi, Oguri, Hiroki, Oikawa, Hideaki

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

18

Structure of the Myotonic Dystrophy Type 2 RNA and Designed Small Molecules That Reduce Toxicity

Childs-Disney, Jessica L., Yildirim, Ilyas, Park, HaJeung, Lohman, Jeremy R., Guan, Lirui, Tran, Tuan, Sarkar, Partha, Schatz, George C., Disney, Matthew D.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

19

Inhibiting AMPylation: A Novel Screen To Identify the First Small Molecule Inhibitors of Protein AMPylation

Lewallen, Daniel M., Sreelatha, Anju, Dharmarajan, Venkatasubramanian, Madoux, Franck, Chase, Peter, Griffin, Patrick R., Orth, Kim, Hodder, Peter, Thompson, Paul R.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.27 MB

english, 2014

20

Reports from the Chemical Biology of Texas Symposium at the 69th Southwest Regional Meeting of the American Chemical Society

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 293 KB

english, 2014

21

Spotlight

Gordon, Eva J., Underwood, Jason G., Webb, Sarah A.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

22

Crystal Structure of Bacillus cereus Class Ib Ribonucleotide Reductase Di-iron NrdF in Complex with NrdI

Hammerstad, Marta, Hersleth, Hans-Petter, Tomter, Ane B., Røhr, Åsmund K., Andersson, K. Kristoffer

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 7.11 MB

english, 2014

23

Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer’s Disease Associated Aβ 42 Peptide

Bolognesi, Benedetta, Cohen, Samuel I. A., Aran Terol, Pablo, Esbjörner, Elin K., Giorgetti, Sofia, Mossuto, Maria F., Natalello, Antonino, Brorsson, Ann-Christin, Knowles, Tuomas P. J., Dobson, Chris

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

24

Cupric Yersiniabactin Is a Virulence-Associated Superoxide Dismutase Mimic

Chaturvedi, Kaveri S., Hung, Chia S., Giblin, Daryl E., Urushidani, Saki, Austin, Anthony M., Dinauer, Mary C., Henderson, Jeffrey P.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.49 MB

english, 2014

25

Prometastatic GPCR CD97 Is a Direct Target of Tumor Suppressor microRNA-126

Lu, Ying Y., Sweredoski, Michael J., Huss, David, Lansford, Rusty, Hess, Sonja, Tirrell, David A.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 761 KB

english, 2014

26

Time- and Concentration-Dependent Effects of Exogenous Serotonin and Inflammatory Cytokines on Mast Cell Function

Gruba, Sarah M., Meyer, Audrey F., Manning, Benjamin M., Wang, Yiwen, Thompson, John W., Dalluge, Joseph J., Haynes, Christy L.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

27

Rational Design of Matrix Metalloproteinase-13 Activatable Probes for Enhanced Specificity

Zhu, Lei, Ma, Ying, Kiesewetter, Dale O., Wang, Ye, Lang, Lixin, Lee, Seulki, Niu, Gang, Chen, Xiaoyuan

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

28

Studying Weak and Dynamic Interactions of Posttranslationally Modified Proteins using Expressed Protein Ligation

Tripsianes, Konstantinos, Chu, Nam K., Friberg, Anders, Sattler, Michael, Becker, Christian F. W.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

29

Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division

Rebets, Yuriy, Lupoli, Tania, Qiao, Yuan, Schirner, Kathrin, Villet, Regis, Hooper, David, Kahne, Daniel, Walker, Suzanne

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.06 MB

english, 2014

30

Mechanistic Insights from Reaction of α-Oxiranyl-Aldehydes with Cyanobacterial Aldehyde Deformylating Oxygenase

Das, Debasis, Ellington, Benjamin, Paul, Bishwajit, Marsh, E. Neil G.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

31

Introducing Our Authors

Powell, Rachelle

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 786 KB

english, 2014

32

Multidimensional Profiling Platforms Reveal Metabolic Dysregulation Caused by Organophosphorus Pesticides

Medina-Cleghorn, Daniel, Heslin, Ann, Morris, Patrick J., Mulvihill, Melinda M., Nomura, Daniel K.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.01 MB

english, 2014

33

Encapsulation of an Enzyme Cascade within the Bacteriophage P22 Virus-Like Particle

Patterson, Dustin P., Schwarz, Benjamin, Waters, Ryan S., Gedeon, Tomas, Douglas, Trevor

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.98 MB

english, 2014

34

In This Issue

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 471 KB

english, 2014

35

Integrating Chemical and Genetic Silencing Strategies To Identify Host Kinase-Phosphatase Inhibitor Networks That Control Bacterial Infection

Albers, Harald M. H. G., Kuijl, Coenraad, Bakker, Jeroen, Hendrickx, Loes, Wekker, Sharida, Farhou, Nadha, Liu, Nora, Blasco-Moreno, Bernat, Scanu, Tiziana, den Hertog, Jeroen, Celie, Patrick, Ovaa, H

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014