Volume 12; Issue 1

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ACS Chemical Neuroscience
Volume 12; Issue 1

ACS Chemical Neuroscience

Volume 12; Issue 1

1

Effect of a 5-HT7 Receptor Antagonist on Reversal Learning in the Rat Attentional Set-Shifting Test

Hrnjadovic, Alma, Friedmann, James, Barhebreus, Sandra, Allen, Patricia J., Kocsis, Bernat

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 1.69 MB

2021

2

Exposure of Î²6/Î²7-Loop in Zn/Cu Superoxide Dismutase (SOD1) Is Coupled to Metal Loss and Is Transiently Reversible During Misfolding

Bakavayev, Shamchal, Argueti, Shirel, Venkatachalam, Nachiyappan, Yehezkel, Galit, Stavsky, Alexandra, Barak, Zeev, Israelson, Adrian, Engel, Stanislav

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 4.73 MB

2021

3

Current Status of Tissue Clearing and the Path Forward in Neuroscience

Zhao, Jiajia, Lai, Hei Ming, Qi, Yuwei, He, Dian, Sun, Haitao

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 2.70 MB

2021

4

Orally Administered Benzofuran Derivative Disaggregated AÎ² Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse

Kim, DaWon, Bae, Gi Hun, Kim, Hye Yun, Jeon, Hanna, Kim, Kyeonghwan, Shin, Jisu, Lee, Sunhee, Hong, Seungpyo, Kim, Ikyon, Kim, YoungSoo

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 4.43 MB

2021

5

Inhibitory Effects of Isobavachalcone on Tau Protein Aggregation, Tau Phosphorylation, and Oligomeric Tau-Induced Apoptosis

Xiao, Shifeng, Wu, Qiuping, Yao, Xuanbao, Zhang, Jiahao, Zhong, Weicong, Zhao, Junyi, Liu, Qiong, Zhang, Mohan

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 6.03 MB

2021

6

Characterization of Kinetic Isotope Effects and Label Loss in Deuterium-Based Isotopic Labeling Studies

de Graaf, Robin A., Thomas, Monique A., Behar, Kevin L., De Feyter, Henk M.

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 1.79 MB

2021

7

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N -Methyl- d -aspartate Receptors

Strong, Katie L., Epplin, Matthew P., Ogden, Kevin K., Burger, Pieter B., Kaiser, Thomas M., Wilding, Timothy J., Kusumoto, Hiro, Camp, Chad R., Shaulsky, Gil, Bhattacharya, Subhrajit, Perszyk, Riley

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 9.36 MB

2021

8

Recent Advances in Virtual Screening for Cholinesterase Inhibitors

Miles, Jared A., Ross, Benjamin P.

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 3.31 MB

2021

9

SAR Matrices Enable Discovery of Mixed Efficacy Î¼-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore

Henry, Sean, Anand, Jessica P., Brinkel, Ashley C., McMillan, Douglas M., Twarozynski, Jack. J., Loo, Christian E., Traynor, John R., Mosberg, Henry I.

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 2.39 MB

2021

10

Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone

Zhang, Chun-Hui, Kim, Kyungbo, Jin, Zhenyu, Zheng, Fang, Zhan, Chang-Guo

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 3.56 MB

2021

11

Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

Sampaio-Dias, Ivo E., RodrÃguez-Borges, JosÃ© E., YÃ¡Ã±ez-PÃ©rez, VÃctor, Arrasate, Sonia, Llorente, Javier, Brea, JosÃ© M., Bediaga, Harbil, ViÃ±a, Dolores, Loza, MarÃa Isabel, CaamaÃ±o, Olga, Gar

Journal:

ACS Chemical Neuroscience

Year:

2021

File:

PDF, 1.37 MB

2021