Volume 8; Issue 4

ACS Chemical Neuroscience

Volume 8; Issue 4

1

Enhanced Brain Delivery of Dimethyl Fumarate Employing Tocopherol-Acetate-Based Nanolipidic Carriers: Evidence from Pharmacokinetic, Biodistribution, and Cellular Uptake Studies

Kumar, Pramod, Sharma, Gajanand, Kumar, Rajendra, Malik, Ruchi, Singh, Bhupinder, Katare, O. P., Raza, Kaisar

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

2

Biological Insights of the Dopaminergic Stabilizer ACR16 at the Binding Pocket of Dopamine D2 Receptor

Ekhteiari Salmas, Ramin, Seeman, Philip, Aksoydan, Busecan, Stein, Matthias, Yurtsever, Mine, Durdagi, Serdar

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 5.43 MB

english, 2017

3

Diverse Effects on M 1 Signaling and Adverse Effect Liability within a Series of M 1 Ago-PAMs

Rook, Jerri M., Abe, Masahito, Cho, Hyekyung P., Nance, Kellie D., Luscombe, Vincent B., Adams, Jeffrey J., Dickerson, Jonathan W., Remke, Daniel H., Garcia-Barrantes, Pedro M., Engers, Darren W., Eng

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.29 MB

english, 2017

4

Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases

Macdonald, Joanna, Henri, Justin, Goodman, Lynda, Xiang, Dongxi, Duan, Wei, Shigdar, Sarah

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

5

Synthetic Models of Quasi-Stable Amyloid β40 Oligomers with Significant Neurotoxicity

Irie, Yumi, Murakami, Kazuma, Hanaki, Mizuho, Hanaki, Yusuke, Suzuki, Takashi, Monobe, Yoko, Takai, Tomoyo, Akagi, Ken-ichi, Kawase, Taiji, Hirose, Kenji, Irie, Kazuhiro

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 8.59 MB

english, 2017

6

The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent κ-Opioid Agonistic Activities

Li, Wei, Long, Jian-Dong, Qian, Yuan-Yuan, Long, Yu, Xu, Xue-Jun, Wang, Yu-Jun, Shen, Qing, Wang, Zuo-Neng, Yang, Xi-Cheng, Xiao, Li, Sun, Hong-Peng, Xu, Yu-Long, Chen, Yi-Yi, Xie, Qiong, Wang, Yong-H

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

7

Oxidation of Iron under Physiologically Relevant Conditions in Biological Fluids from Healthy and Alzheimer’s Disease Subjects

Lam, Linh Q., Wong, Bruce X., Frugier, Tony, Li, Qiao-Xin, Collins, Steven J., Bush, Ashley I., Crack, Peter J., Duce, James A.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.55 MB

english, 2017

8

Neuroprotective Effects of a Structurally New Family of High Affinity Imidazoline I 2 Receptor Ligands

Abás, Sònia, Erdozain, Amaia M., Keller, Benjamin, Rodríguez-Arévalo, Sergio, Callado, Luis F., García-Sevilla, Jesús A., Escolano, Carmen

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

9

Inhibition and Degradation of Amyloid Beta (Aβ40) Fibrillation by Designed Small Peptide: A Combined Spectroscopy, Microscopy, and Cell Toxicity Study

Ghosh, Anirban, Pradhan, Nibedita, Bera, Swapna, Datta, Aritreyee, Krishnamoorthy, Janarthanan, Jana, Nikhil R., Bhunia, Anirban

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

10

Neurotoxicity of β-Keto Amphetamines: Deathly Mechanisms Elicited by Methylone and MDPV in Human Dopaminergic SH-SY5Y Cells

Valente, Maria João, Bastos, Maria de Lourdes, Fernandes, Eduarda, Carvalho, Félix, Guedes de Pinho, Paula, Carvalho, Márcia

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 3.04 MB

english, 2017

11

The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons

Chua, Sook Wern, Cornejo, Alberto, van Eersel, Janet, Stevens, Claire H., Vaca, Inmaculada, Cueto, Mercedes, Kassiou, Michael, Gladbach, Amadeus, Macmillan, Alex, Lewis, Lev, Whan, Renee, Ittner, Lars

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 6.92 MB

english, 2017

12

Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils

Xu, Liang, Ma, Buyong, Nussinov, Ruth, Thompson, Damien

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.59 MB

english, 2017

13

Development of Phenothiazine-Based Theranostic Compounds That Act Both as Inhibitors of β-Amyloid Aggregation and as Imaging Probes for Amyloid Plaques in Alzheimer’s Disease

Dao, Pascal, Ye, Feifei, Liu, Yan, Du, Zhi Yun, Zhang, Kun, Dong, Chang Zhi, Meunier, Bernard, Chen, Huixiong

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 831 KB

english, 2017

14

Bacoside-A, an Indian Traditional-Medicine Substance, Inhibits β-Amyloid Cytotoxicity, Fibrillation, and Membrane Interactions

Malishev, Ravit, Shaham-Niv, Shira, Nandi, Sukhendu, Kolusheva, Sofiya, Gazit, Ehud, Jelinek, Raz

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

15

Chronic Mild Stress-Induced Alterations of Local Protein Synthesis: A Role for Cognitive Impairment

Calabrese, Francesca, Brivio, Paola, Gruca, Piotr, Lason-Tyburkiewicz, Magdalena, Papp, Mariusz, Riva, Marco A.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

16

In Vivo Systems Response Profiling and Multivariate Classification of CNS Active Compounds: A Structured Tool for CNS Drug Discovery

Waters, Susanna, Svensson, Peder, Kullingsjö, Johan, Pontén, Henrik, Andreasson, Theresa, Sunesson, Ylva, Ljung, Elisabeth, Sonesson, Clas, Waters, Nicholas

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

17

Ethylatropine Bromide as a Peripherally Restricted Muscarinic Antagonist

Rojas, Asheebo, Ganesh, Thota, Walker, Alec, Dingledine, Raymond

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

18

A Novel Iron(II) Preferring Dopamine Agonist Chelator as Potential Symptomatic and Neuroprotective Therapeutic Agent for Parkinson’s Disease

Das, Banibrata, Kandegedara, Ashoka, Xu, Liping, Antonio, Tamara, Stemmler, Timothy, Reith, Maarten E. A., Dutta, Aloke K.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 3.13 MB

english, 2017

19

Sophorolipid Butyl Ester Diacetate Does Not Affect Macrophage Polarization but Enhances Astrocytic Glial Fibrillary Acidic Protein Expression at Micromolar Concentrations in Vitro

Ziemba, Alexis M., Gottipati, Manoj K., Totsingan, Filbert, Hanes, Cheryl M., Gross, Richard A., Lennartz, Michelle R., Gilbert, Ryan J.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

20

Evidence of Molecular Interactions of Aβ1–42 with N-Terminal Truncated Beta Amyloids by NMR

Tomaselli, Simona, Pagano, Katiuscia, D’Arrigo, Cristina, Molinari, Henriette, Ragona, Laura

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 663 KB

english, 2017

21

Proteomic Analysis of Postsynaptic Protein Complexes Underlying Neuronal Plasticity

Baucum, Anthony J.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 61.01 MB

english, 2017

22

Targeting Brain-Eating Amoebae Infections

Khan, Naveed Ahmed, Ong, Timothy Yu Yee, Siddiqui, Ruqaiyyah

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 127 KB

english, 2017

23

Are Dopamine Oxidation Metabolites Involved in the Loss of Dopaminergic Neurons in the Nigrostriatal System in Parkinson’s Disease?

Herrera, Andrea, Muñoz, Patricia, Steinbusch, Harry W. M., Segura-Aguilar, Juan

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

24

Issue Editorial Masthead

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 161 KB

english, 2017

25

Issue Publication Information

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 157 KB

english, 2017

26

In This Issue, Volume 8, Issue 4

Weidmann, Alyson G.

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

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