Volume 301; Issue 1-2

Molecular and Cellular Endocrinology

Volume 301; Issue 1-2

1

Steroid-converting enzymes in human ovarian carcinomas

Justin C. Chura, Hyung S. Ryu, Marc Simard, Donald Poirier, Yves Tremblay, Doris C. Brooker, Charles H. Blomquist, Peter A. Argenta

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

2

Disturbed estrogen and progesterone action in ovarian endometriosis

Tina Šmuc, Neli Hevir, Martina Ribič-Pucelj, Bettina Husen, Hubert Thole, Tea Lanišnik Rižner

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 2.98 MB

english, 2009

3

Comparison of predicted and experimental subcellular localization of two putative rat steroid dehydrogenases from the short-chain dehydrogenase/reductase protein superfamily

Brigitte Keller, Marc Meier, Jerzy Adamski

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 406 KB

english, 2009

4

Mutations that affect coenzyme binding and dimer formation of fungal 17β-hydroxysteroid dehydrogenase

Mojca Brunskole, Katja Kristan, Jure Stojan, Tea Lanišnik Rižner

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 440 KB

english, 2009

5

Discovery of new inhibitors of aldo-keto reductase 1C1 by structure-based virtual screening

Petra Brožič, Samo Turk, Tea Lanišnik Rižner, Stanislav Gobec

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 593 KB

english, 2009

6

The design of novel 17β-hydroxysteroid dehydrogenase type 3 inhibitors

Nigel Vicker, Christopher M. Sharland, Wesley B. Heaton, Ana M. Ramos Gonzalez, Helen V. Bailey, Andrew Smith, Jeremy S. Springall, Joanna M. Day, Helena J. Tutill, Michael J. Reed, Atul Purohit, Barr

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 907 KB

english, 2009

7

Discovery of novel inhibitors of human 11β-hydroxysteroid dehydrogenase type 1

Xiangdong Su, Nigel Vicker, Melanie Trusselle, Heather Halem, Michael D. Culler, Barry V.L. Potter

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 417 KB

english, 2009

8

11β-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP+ and is stimulated by extracellular glucose

Anna A. Dzyakanchuk, Zoltán Balázs, Lyubomir G. Nashev, Kurt E. Amrein, Alex Odermatt

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

9

3β-Hydroxysteroid dehydrogenases and pre-receptor steroid metabolism in the human ovarian surface epithelium

Georgia Papacleovoulou, Richard J. Edmondson, Hilary O.D. Critchley, Stephen G. Hillier, J. Ian Mason

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

10

Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17β-hydroxysteroid dehydrogenase Type 3

Joanna M. Day, Helena J. Tutill, Paul A. Foster, Helen V. Bailey, Wesley B. Heaton, Christopher M. Sharland, Nigel Vicker, Barry V.L. Potter, Atul Purohit, Michael J. Reed

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 714 KB

english, 2009

11

Relative involvement of three 17β-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors

Yannick Laplante, Claudine Rancourt, Donald Poirier

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 314 KB

english, 2009

12

Estrogen formation in endometrial and cervix cancer cell lines: Involvement of aromatase, steroid sulfatase and 17β-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12)

Michelle-Audrey Fournier, Donald Poirier

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 227 KB

english, 2009

13

11β-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds

Andreas Blum, Angelo D. Favia, Edmund Maser

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 662 KB

english, 2009

14

Androgens, estrogens, and hydroxysteroid dehydrogenases

Dario Mizrachi, Richard J. Auchus

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.38 MB

english, 2009

15

Pharmacophore modelling of 17β-HSD1 enzyme based on active inhibitors and enzyme structure

Sampo Karkola, Sari Alho-Richmond, Kristiina Wahala

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 544 KB

english, 2009

16

Flavonoids and cinnamic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 1

Petra Brožič, Petra Kocbek, Matej Sova, Julijana Kristl, Stefan Martens, Jerzy Adamski, Stanislav Gobec, Tea Lanišnik Rižner

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 372 KB

english, 2009

17

The role of the heterocycle in bis(hydroxyphenyl)triazoles for inhibition of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) type 1 and type 2

Yaseen A. Al-Soud, Emmanuel Bey, Alexander Oster, Sandrine Marchais-Oberwinkler, Ruth Werth, Patricia Kruchten, Martin Frotscher, Rolf W. Hartmann

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

18

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

Luigi Di Costanzo, Jason E. Drury, David W. Christianson, Trevor M. Penning

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

19

Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer

Tina Šmuc, Tea Lanišnik Rižner

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 2.14 MB

english, 2009

20

Structure–activity study in the class of 6-(3′-hydroxyphenyl)naphthalenes leading to an optimization of a pharmacophore model for 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitors

Sandrine Marchais-Oberwinkler, Martin Frotscher, Erika Ziegler, Ruth Werth, Patricia Kruchten, Josef Messinger, Hubert Thole, Rolf W. Hartmann

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

21

Structural basis for the selective inhibition of human 3β-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells

James L. Thomas, Kevin M. Bucholtz, Jingping Sun, Vance L. Mack, Balint Kacsoh

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.58 MB

english, 2009

22

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in the inflammatory response

Karen E. Chapman, Agnes E. Coutinho, Mohini Gray, James S. Gilmour, John S. Savill, Jonathan R. Seckl

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

23

Development of a biological screening system for the evaluation of highly active and selective 17β-HSD1-inhibitors as potential therapeutic agents

Patricia Kruchten, Ruth Werth, Sandrine Marchais-Oberwinkler, Martin Frotscher, Rolf W. Hartmann

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 367 KB

english, 2009

24

Steroid metabolism in cnidarians: Insights from Nematostella vectensis

Ann M. Tarrant, Adam M. Reitzel, Charles H. Blomquist, Ferdinand Haller, Janina Tokarz, Jerzy Adamski

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 725 KB

english, 2009

25

Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms

Malin Hult, Henrik Ortsäter, Gertrud Schuster, Florian Graedler, Johannes Beckers, Jerzy Adamski, Alexander Ploner, Hans Jörnvall, Peter Bergsten, Udo Oppermann

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

26

Structure–activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4

Wen Hwa Lee, Petra Lukacik, Kunde Guo, Emilie Ugochukwu, Kathryn L. Kavanagh, Brian Marsden, Udo Oppermann

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.91 MB

english, 2009

27

The binding of lignans, flavonoids and coumestrol to CYP450 aromatase: A molecular modelling study

Sampo Karkola, Kristiina Wähälä

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 903 KB

english, 2009

28

Challenges and developments in tandem mass spectrometry based clinical metabolomics

Uta Ceglarek, Alexander Leichtle, Mathias Brügel, Linda Kortz, Romy Brauer, Kristin Bresler, Joachim Thiery, Georg Martin Fiedler

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 768 KB

english, 2009

29

DHEA metabolism in prostate: For better or worse?

Julia T. Arnold

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

30

Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11β-hydroxysteroid dehydrogenase 1

Zoltán Balázs, Lyubomir G. Nashev, Charlie Chandsawangbhuwana, Michael E. Baker, Alex Odermatt

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

31

Estrone C15 derivatives—A new class of 17β-hydroxysteroid dehydrogenase type 1 inhibitors

Josef Messinger, Bettina Husen, Pasi Koskimies, Leena Hirvelä, Lila Kallio, Pauli Saarenketo, Hubert Thole

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 2.79 MB

english, 2009

32

Aldosterone and mineralocorticoid receptors: Clinical studies and basic biology

John W. Funder, Anastasia S. Mihailidou

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

33

Expression profiles of human 11β-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases

J.P. Stegk, B. Ebert, H.-J. Martin, E. Maser

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 395 KB

english, 2009

34

In vivo mouse model for analysis of hydroxysteroid (17β) dehydrogenase 1 inhibitors

Tarja Lamminen, Taija Saloniemi, Kaisa Huhtinen, Pasi Koskimies, Josef Messinger, Bettina Husen, Hubert Thole, Matti Poutanen

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

35

Androgen metabolism in adipose tissue: Recent advances

Karine Blouin, Alain Veilleux, Van Luu-The, André Tchernof

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

36

Integrated view on 17beta-hydroxysteroid dehydrogenases

Gabriele Moeller, Jerzy Adamski

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

37

Reductive 17β-hydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer

Juliette A. Aka, Mausumi Mazumdar, Sheng-Xiang Lin

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 814 KB

english, 2009

38

Human HSD17B1 expression masculinizes transgenic female mice

Taija Saloniemi, Michelle Welsh, Tarja Lamminen, Philippa Saunders, Sari Mäkelä, Tomi Streng, Matti Poutanen

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 4.83 MB

english, 2009

39

HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer

Krishan K. Rasiah, Margaret Gardiner-Garden, Emma J.D. Padilla, Gabriele Möller, James G. Kench, M. Chehani Alles, Sarah A. Eggleton, Phillip D. Stricker, Jerzy Adamski, Robert L. Sutherland, Susan M.

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.10 MB

english, 2009

40

Zebrafish 17beta-hydroxysteroid dehydrogenases: An evolutionary perspective

R. Mindnich, J. Adamski

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 233 KB

english, 2009

41

Pre-receptor steroid metabolism as target for pharmacological treatment

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

42

Editorial Board

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 44 KB

english, 2009

43

Steroid measurement with LC–MS/MS in pediatric endocrinology

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 646 KB

english, 2009

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