Volume 11; Issue 5

Molecular Cancer Therapeutics

Volume 11; Issue 5

1

Triggering Fbw7-Mediated Proteasomal Degradation of c-Myc by Oridonin Induces Cell Growth Inhibition and Apoptosis

Huang, H.-L., Weng, H.-Y., Wang, L.-Q., Yu, C.-H., Huang, Q.-J., Zhao, P.-P., Wen, J.-Z., Zhou, H., Qu, L.-H.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.19 MB

english, 2012

2

Quantitative Proteomic Profiling Identifies Protein Correlates to EGFR Kinase Inhibition

Kani, K., Faca, V. M., Hughes, L. D., Zhang, W., Fang, Q., Shahbaba, B., Luethy, R., Erde, J., Schmidt, J., Pitteri, S. J.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

3

High TUBB3 Expression, an Independent Prognostic Marker in Patients with Early Non-Small Cell Lung Cancer Treated by Preoperative Chemotherapy, Is Regulated by K-Ras Signaling Pathway

Levallet, G., Bergot, E., Antoine, M., Creveuil, C., Santos, A. O., Beau-Faller, M., de Fraipont, F., Brambilla, E., Levallet, J., Morin, F., Westeel, V., Wislez, M., Quoix, E., Debieuvre, D., Dubois,

Journal:

Molecular Cancer Therapeutics

Year:

2012

File:

PDF, 57 KB

2012

4

miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition Signaling

Ru, P., Steele, R., Newhall, P., Phillips, N. J., Toth, K., Ray, R. B.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 637 KB

english, 2012

5

Attacking a Nexus of the Oncogenic Circuitry by Reversing Aberrant eIF4F-Mediated Translation

Bitterman, P. B., Polunovsky, V. A.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

6

JAK-STAT and JAK-PI3K-mTORC1 Pathways Regulate Telomerase Transcriptionally and Posttranslationally in ATL Cells

Yamada, O., Ozaki, K., Akiyama, M., Kawauchi, K.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

7

ERK Inhibition Overcomes Acquired Resistance to MEK Inhibitors

Hatzivassiliou, G., Liu, B., O'Brien, C., Spoerke, J. M., Hoeflich, K. P., Haverty, P. M., Soriano, R., Forrest, W. F., Heldens, S., Chen, H., Toy, K., Ha, C., Zhou, W., Song, K., Friedman, L. S., Aml

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

8

Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

Williams, T. M., Flecha, A. R., Keller, P., Ram, A., Karnak, D., Galban, S., Galban, C. J., Ross, B. D., Lawrence, T. S., Rehemtulla, A., Sebolt-Leopold, J.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 918 KB

english, 2012

9

Immunotherapy of Cancer with 4-1BB

Vinay, D. S., Kwon, B. S.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

10

Off-Target Function of the Sonic Hedgehog Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide-Dependent Neutral Sphingomyelinase 2/Ceramide Induction

Meyers-Needham, M., Lewis, J. A., Gencer, S., Sentelle, R. D., Saddoughi, S. A., Clarke, C. J., Hannun, Y. A., Norell, H., da Palma, T. M., Nishimura, M., Kraveka, J. M., Khavandgar, Z., Murshed, M.,

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.06 MB

english, 2012

11

The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates

Erickson, H. K., Lewis Phillips, G. D., Leipold, D. D., Provenzano, C. A., Mai, E., Johnson, H. A., Gunter, B., Audette, C. A., Gupta, M., Pinkas, J., Tibbitts, J.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

12

Multiple Antigenic Peptides Based on H-2Kb-Restricted CTL Epitopes from Murine Heparanase Induce a Potent Antitumor Immune Response In Vivo

Tang, X.-D., Wang, G.-Z., Guo, J., Lu, M.-H., Li, C., Li, N., Chao, Y.-L., Li, C.-Z., Wu, Y.-Y., Hu, C.-J., Fang, D.-C., Yang, S.-M.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 926 KB

english, 2012

13

Evading Pgp Activity in Drug-Resistant Cancer Cells: A Structural and Functional Study of Antitubulin Furan Metotica Compounds

Nguyen, T. L., Cera, M. R., Pinto, A., Lo Presti, L., Hamel, E., Conti, P., Gussio, R., De Wulf, P.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

14

Correction: Narciclasine, a Plant Growth Modulator, Activates Rho and Stress Fibers in Glioblastoma Cells

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

15

Retraction in Part: A Genomic Approach to Identify Molecular Pathways Associated with Chemotherapy Resistance

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 154 KB

english, 2012

16

Hyperactivation of 4E-Binding Protein 1 as a Mediator of Biguanide-Induced Cytotoxicity during Glucose Deprivation

Matsuo, J., Tsukumo, Y., Saito, S., Tsukahara, S., Sakurai, J., Sato, S., Kondo, H., Ushijima, M., Matsuura, M., Watanabe, T., Tomida, A.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1000 KB

english, 2012

17

Therapeutic Significance of Estrogen Receptor Agonists in Gliomas

Sareddy, G. R., Nair, B. C., Gonugunta, V. K., Zhang, Q.-g., Brenner, A., Brann, D. W., Tekmal, R. R., Vadlamudi, R. K.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 975 KB

english, 2012

18

Obatoclax Interacts Synergistically with the Irreversible Proteasome Inhibitor Carfilzomib in GC- and ABC-DLBCL Cells In Vitro and In Vivo

Dasmahapatra, G., Lembersky, D., Son, M. P., Patel, H., Peterson, D., Attkisson, E., Fisher, R. I., Friedberg, J. W., Dent, P., Grant, S.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 957 KB

english, 2012