Volume 12; Issue 5

Molecular Cancer Therapeutics

Volume 12; Issue 5

1

Designing and Developing S100P Inhibitor 5-Methyl Cromolyn for Pancreatic Cancer Therapy

Arumugam, T., Ramachandran, V., Sun, D., Peng, Z., Pal, A., Maxwell, D. S., Bornmann, W. G., Logsdon, C. D.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 488 KB

english, 2013

2

Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells

Zheng, X., He, K., Zhang, L., Yu, J.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

3

Inhibition of Mutant GNAQ Signaling in Uveal Melanoma Induces AMPK-Dependent Autophagic Cell Death

Ambrosini, G., Musi, E., Ho, A. L., de Stanchina, E., Schwartz, G. K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 6.10 MB

english, 2013

4

Small-Molecule Inhibitors of Acetyltransferase p300 Identified by High-Throughput Screening Are Potent Anticancer Agents

Yang, H., Pinello, C. E., Luo, J., Li, D., Wang, Y., Zhao, L. Y., Jahn, S. C., Saldanha, S. A., Planck, J., Geary, K. R., Ma, H., Law, B. K., Roush, W. R., Hodder, P., Liao, D.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

5

New Paradigms in Microtubule-Mediated Endocrine Signaling in Prostate Cancer

Mistry, S. J., Oh, W. K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 525 KB

english, 2013

6

Afatinib Prolongs Survival Compared with Gefitinib in an Epidermal Growth Factor Receptor-Driven Lung Cancer Model

Ninomiya, T., Takigawa, N., Ichihara, E., Ochi, N., Murakami, T., Honda, Y., Kubo, T., Minami, D., Kudo, K., Tanimoto, M., Kiura, K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.42 MB

english, 2013

7

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

Hochhauser, D., Glynne-Jones, R., Potter, V., Gravalos, C., Doyle, T. J., Pathiraja, K., Zhang, Q., Zhang, L., Sausville, E. A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 213 KB

english, 2013

8

A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of Autophagy

Gurpinar, E., Grizzle, W. E., Shacka, J. J., Mader, B. J., Li, N., Piazza, N. A., Russo, S., Keeton, A. B., Piazza, G. A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

9

Activity of a Py-Im Polyamide Targeted to the Estrogen Response Element

Nickols, N. G., Szablowski, J. O., Hargrove, A. E., Li, B. C., Raskatov, J. A., Dervan, P. B.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 816 KB

english, 2013

10

Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents

Sharma, S., Zeng, J.-Y., Zhuang, C.-M., Zhou, Y.-Q., Yao, H.-P., Hu, X., Zhang, R., Wang, M.-H.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

11

A Novel Monoclonal Antibody to Secreted Frizzled-Related Protein 2 Inhibits Tumor Growth

Fontenot, E., Rossi, E., Mumper, R., Snyder, S., Siamakpour-Reihani, S., Ma, P., Hilliard, E., Bone, B., Ketelsen, D., Santos, C., Patterson, C., Klauber-DeMore, N.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

12

Colorectal Cancer Cells Refractory to Anti-VEGF Treatment Are Vulnerable to Glycolytic Blockade due to Persistent Impairment of Mitochondria

Xu, J., Wang, J., Xu, B., Ge, H., Zhou, X., Fang, J.-Y.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.50 MB

english, 2013

13

[18F]-FLT Positron Emission Tomography Can Be Used to Image the Response of Sensitive Tumors to PI3-Kinase Inhibition with the Novel Agent GDC-0941

Cawthorne, C., Burrows, N., Gieling, R. G., Morrow, C. J., Forster, D., Gregory, J., Radigois, M., Smigova, A., Babur, M., Simpson, K., Hodgkinson, C., Brown, G., McMahon, A., Dive, C., Hiscock, D., W

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.34 MB

english, 2013

14

Targeting CXCR2 Enhances Chemotherapeutic Response, Inhibits Mammary Tumor Growth, Angiogenesis, and Lung Metastasis

Sharma, B., Nawandar, D. M., Nannuru, K. C., Varney, M. L., Singh, R. K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

15

ALK Inhibitor PF02341066 (Crizotinib) Increases Sensitivity to Radiation in Non-Small Cell Lung Cancer Expressing EML4-ALK

Sun, Y., Nowak, K. A., Zaorsky, N. G., Winchester, C.-L., Dalal, K., Giacalone, N. J., Liu, N., Werner-Wasik, M., Wasik, M. A., Dicker, A. P., Lu, B.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 746 KB

english, 2013

16

Targeting FoxM1 Effectively Retards p53-Null Lymphoma and Sarcoma

Wang, Z., Zheng, Y., Park, H. J., Li, J., Carr, J. R., Chen, Y.-j., Kiefer, M. M., Kopanja, D., Bagchi, S., Tyner, A. L., Raychaudhuri, P.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

17

Spongian Diterpenoids Inhibit Androgen Receptor Activity

Yang, Y. C., Meimetis, L. G., Tien, A. H., Mawji, N. R., Carr, G., Wang, J., Andersen, R. J., Sadar, M. D.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

18

Impact of Tumor Vascularity on Responsiveness to Antiangiogenesis in a Prostate Cancer Stem Cell-Derived Tumor Model

Zhang, K., Waxman, D. J.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

19

Activity of the Fibroblast Growth Factor Receptor Inhibitors Dovitinib (TKI258) and NVP-BGJ398 in Human Endometrial Cancer Cells

Konecny, G. E., Kolarova, T., O'Brien, N. A., Winterhoff, B., Yang, G., Qi, J., Qi, Z., Venkatesan, N., Ayala, R., Luo, T., Finn, R. S., Kristof, J., Galderisi, C., Porta, D. G., Anderson, L., Shi, M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 897 KB

english, 2013

20

A Novel Antiandrogen, Compound 30, Suppresses Castration-Resistant and MDV3100-Resistant Prostate Cancer Growth In Vitro and In Vivo

Kuruma, H., Matsumoto, H., Shiota, M., Bishop, J., Lamoureux, F., Thomas, C., Briere, D., Los, G., Gleave, M., Fanjul, A., Zoubeidi, A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 749 KB

english, 2013

21

The Efficacy of CHK1 Inhibitors Is Not Altered by Hypoxia, but Is Enhanced after Reoxygenation

Hasvold, G., Nahse-Kumpf, V., Tkacz-Stachowska, K., Rofstad, E. K., Syljuasen, R. G.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

22

Tandutinib Inhibits the Akt/mTOR Signaling Pathway to Inhibit Colon Cancer Growth

Ponnurangam, S., Standing, D., Rangarajan, P., Subramaniam, D.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

23

Dual PI3K/AKT/mTOR Inhibitor BEZ235 Synergistically Enhances the Activity of JAK2 Inhibitor against Cultured and Primary Human Myeloproliferative Neoplasm Cells

Fiskus, W., Verstovsek, S., Manshouri, T., Smith, J. E., Peth, K., Abhyankar, S., McGuirk, J., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

24

Bortezomib and SAHA Synergistically Induce ROS-Driven Caspase-Dependent Apoptosis of Nasopharyngeal Carcinoma and Block Replication of Epstein-Barr Virus

Hui, K. F., Lam, B. H. W., Ho, D. N., Tsao, S. W., Chiang, A. K. S.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

25

Y-box Binding Protein-1 Contributes to Both HER2/ErbB2 Expression and Lapatinib Sensitivity in Human Gastric Cancer Cells

Shibata, T., Kan, H., Murakami, Y., Ureshino, H., Watari, K., Kawahara, A., Kage, M., Hattori, S., Ono, M., Kuwano, M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

26

Regression of Lung Cancer by Hypoxia-Sensitizing Ruthenium Polypyridyl Complexes

Yadav, A., Janaratne, T., Krishnan, A., Singhal, S. S., Yadav, S., Dayoub, A. S., Hawkins, D. L., Awasthi, S., MacDonnell, F. M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 687 KB

english, 2013