Volume 12; Issue 7

Molecular Cancer Therapeutics

Volume 12; Issue 7

1

Triptolide Induces the Expression of miR-142-3p: A Negative Regulator of Heat Shock Protein 70 and Pancreatic Cancer Cell Proliferation

MacKenzie, T. N., Mujumdar, N., Banerjee, S., Sangwan, V., Sarver, A., Vickers, S., Subramanian, S., Saluja, A. K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 794 KB

english, 2013

2

DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma

Li, D., Poon, K. A., Yu, S.-F., Dere, R., Go, M., Lau, J., Zheng, B., Elkins, K., Danilenko, D., Kozak, K. R., Chan, P., Chuh, J., Shi, X., Nazzal, D., Fuh, F., McBride, J., Ramakrishnan, V., de Tute,

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 660 KB

english, 2013

3

Drug Repurposing for Gastrointestinal Stromal Tumor

Pessetto, Z. Y., Weir, S. J., Sethi, G., Broward, M. A., Godwin, A. K.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 878 KB

english, 2013

4

Regorafenib Inhibits Growth, Angiogenesis, and Metastasis in a Highly Aggressive, Orthotopic Colon Cancer Model

Abou-Elkacem, L., Arns, S., Brix, G., Gremse, F., Zopf, D., Kiessling, F., Lederle, W.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

5

Fibroblast Growth Factor Receptor 3 Is a Rational Therapeutic Target in Bladder Cancer

Gust, K. M., McConkey, D. J., Awrey, S., Hegarty, P. K., Qing, J., Bondaruk, J., Ashkenazi, A., Czerniak, B., Dinney, C. P., Black, P. C.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

6

The Potential Role of miR-451 in Cancer Diagnosis, Prognosis, and Therapy

Pan, X., Wang, R., Wang, Z.-X.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 467 KB

english, 2013

7

REST Negatively and ISGF3 Positively Regulate the Human STAT1 Gene in Melanoma

Amalraj, J., Cutler, S. J., Ghazawi, I., Boyle, G. M., Ralph, S. J.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 875 KB

english, 2013

8

CRM1 and BRAF Inhibition Synergize and Induce Tumor Regression in BRAF-Mutant Melanoma

Salas Fragomeni, R. A., Chung, H. W., Landesman, Y., Senapedis, W., Saint-Martin, J.-R., Tsao, H., Flaherty, K. T., Shacham, S., Kauffman, M., Cusack, J. C.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

9

Zoledronic Acid Reverses the Epithelial-Mesenchymal Transition and Inhibits Self-Renewal of Breast Cancer Cells through Inactivation of NF- B

Schech, A. J., Kazi, A. A., Gilani, R. A., Brodie, A. H.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

10

Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma

Carlino, M. S., Gowrishankar, K., Saunders, C. A. B., Pupo, G. M., Snoyman, S., Zhang, X. D., Saw, R., Becker, T. M., Kefford, R. F., Long, G. V., Rizos, H.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.83 MB

english, 2013

11

IGF-1R Targeting Increases the Antitumor Effects of DNA-Damaging Agents in SCLC Model: An Opportunity to Increase the Efficacy of Standard Therapy

Ferte, C., Loriot, Y., Clemenson, C., Commo, F., Gombos, A., Bibault, J.-E., Fumagalli, I., Hamama, S., Auger, N., Lahon, B., Chargari, C., Calderaro, J., Soria, J.-C., Deutsch, E.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 2.75 MB

english, 2013

12

Potential Role of mTORC2 as a Therapeutic Target in Clear Cell Carcinoma of the Ovary

Hisamatsu, T., Mabuchi, S., Matsumoto, Y., Kawano, M., Sasano, T., Takahashi, R., Sawada, K., Ito, K., Kurachi, H., Schilder, R. J., Testa, J. R., Kimura, T.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

13

MPT0B098, a Novel Microtubule Inhibitor That Destabilizes the Hypoxia-Inducible Factor-1 mRNA through Decreasing Nuclear-Cytoplasmic Translocation of RNA-Binding Protein HuR

Cheng, Y.-C., Liou, J.-P., Kuo, C.-C., Lai, W.-Y., Shih, K.-H., Chang, C.-Y., Pan, W.-Y., Tseng, J. T., Chang, J.-Y.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

14

Metabolomics Identifies Pyrimidine Starvation as the Mechanism of 5-Aminoimidazole-4-Carboxamide-1- -Riboside-Induced Apoptosis in Multiple Myeloma Cells

Bardeleben, C., Sharma, S., Reeve, J. R., Bassilian, S., Frost, P., Hoang, B., Shi, Y., Lichtenstein, A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

15

CXCR4-Targeted Therapy Inhibits VEGF Expression and Chondrosarcoma Angiogenesis and Metastasis

Sun, X., Charbonneau, C., Wei, L., Yang, W., Chen, Q., Terek, R. M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 648 KB

english, 2013

16

Overlapping Functions of ABC Transporters in Topotecan Disposition as Determined in Gene Knockout Mouse Models

Tiwari, A. K., Zhang, R., Gallo, J. M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

17

Resveratrol Induces Differentiation Markers Expression in Anaplastic Thyroid Carcinoma via Activation of Notch1 Signaling and Suppresses Cell Growth

Yu, X.-M., Jaskula-Sztul, R., Ahmed, K., Harrison, A. D., Kunnimalaiyaan, M., Chen, H.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

18

PG545, an Angiogenesis and Heparanase Inhibitor, Reduces Primary Tumor Growth and Metastasis in Experimental Pancreatic Cancer

Ostapoff, K. T., Awasthi, N., Kutluk Cenik, B., Hinz, S., Dredge, K., Schwarz, R. E., Brekken, R. A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 3.08 MB

english, 2013

19

Human Anti-Macrophage Migration Inhibitory Factor Antibodies Inhibit Growth of Human Prostate Cancer Cells In Vitro and In Vivo

Hussain, F., Freissmuth, M., Volkel, D., Thiele, M., Douillard, P., Antoine, G., Thurner, P., Ehrlich, H., Schwarz, H.-P., Scheiflinger, F., Kerschbaumer, R. J.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 740 KB

english, 2013

20

Multivalent Scaffold Proteins as Superagonists of TRAIL Receptor 2-Induced Apoptosis

Swers, J. S., Grinberg, L., Wang, L., Feng, H., Lekstrom, K., Carrasco, R., Xiao, Z., Inigo, I., Leow, C. C., Wu, H., Tice, D. A., Baca, M.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1003 KB

english, 2013

21

Identification and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells

De Robertis, A., Valensin, S., Rossi, M., Tunici, P., Verani, M., De Rosa, A., Giordano, C., Varrone, M., Nencini, A., Pratelli, C., Benicchi, T., Bakker, A., Hill, J., Sangthongpitag, K., Pendharkar,

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 831 KB

english, 2013