Volume 13; Issue 1

Molecular Cancer Therapeutics

Volume 13; Issue 1

1

Antitumor Effects of Immunotoxins Are Enhanced by Lowering HCK or Treatment with Src Kinase Inhibitors

Liu, X.-F., Xiang, L., FitzGerald, D. J., Pastan, I.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 4.25 MB

english, 2014

2

Tetravalent Antibody-scTRAIL Fusion Proteins with Improved Properties

Seifert, O., Plappert, A., Fellermeier, S., Siegemund, M., Pfizenmaier, K., Kontermann, R. E.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.97 MB

english, 2014

3

Enhanced PI3K p110 Signaling Confers Acquired Lapatinib Resistance That Can Be Effectively Reversed by a p110 -Selective PI3K Inhibitor

Brady, S. W., Zhang, J., Seok, D., Wang, H., Yu, D.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 923 KB

english, 2014

4

Differential and Common DNA Repair Pathways for Topoisomerase I- and II-Targeted Drugs in a Genetic DT40 Repair Cell Screen Panel

Maede, Y., Shimizu, H., Fukushima, T., Kogame, T., Nakamura, T., Miki, T., Takeda, S., Pommier, Y., Murai, J.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 904 KB

english, 2014

5

Surface-Modified Nanoparticles Enhance Transurothelial Penetration and Delivery of Survivin siRNA in Treating Bladder Cancer

Martin, D. T., Steinbach, J. M., Liu, J., Shimizu, S., Kaimakliotis, H. Z., Wheeler, M. A., Hittelman, A. B., Mark Saltzman, W., Weiss, R. M.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

6

Reversible Action of Diaminothiazoles in Cancer Cells Is Implicated by the Induction of a Fast Conformational Change of Tubulin and Suppression of Microtubule Dynamics

Thomas, N. E., Thamkachy, R., Sivakumar, K. C., Sreedevi, K. J., Louis, X. L., Thomas, S. A., Kumar, R., Rajasekharan, K. N., Cassimeris, L., Sengupta, S.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 4.35 MB

english, 2014

7

Combining Antibody-Directed Presentation of IL-15 and 4-1BBL in a Trifunctional Fusion Protein for Cancer Immunotherapy

Kermer, V., Hornig, N., Harder, M., Bondarieva, A., Kontermann, R. E., Muller, D.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

8

Superior Antitumor Activity of a Novel Bispecific Antibody Cotargeting Human Epidermal Growth Factor Receptor 2 and Type I Insulin-like Growth Factor Receptor

Chen, C., Zhang, Y., Zhang, Y., Li, J., Tsao, S. W., Zhang, M.-Y.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 767 KB

english, 2014

9

Protein-Tyrosine Phosphatase H1 Increases Breast Cancer Sensitivity to Antiestrogens by Dephosphorylating Estrogen Receptor at Tyr537

Suresh, P. S., Ma, S., Migliaccio, A., Chen, G.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.63 MB

english, 2014

10

Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcomes Vemurafenib Acquired Resistance in BRAFV600E Melanoma

Wang, J., Chen, J., Miller, D. D., Li, W.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.13 MB

english, 2014

11

Proteomics of Cancer Cell Lines Resistant to Microtubule-Stabilizing Agents

Albrethsen, J., Angeletti, R. H., Horwitz, S. B., Yang, C.-P. H.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

12

The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1 Activity by Changing miR Expression Patterns in Human Cancer Cells

Bertozzi, D., Marinello, J., Manzo, S. G., Fornari, F., Gramantieri, L., Capranico, G.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 732 KB

english, 2014

13

Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells

Zeng, J.-Y., Sharma, S., Zhou, Y.-Q., Yao, H.-P., Hu, X., Zhang, R., Wang, M.-H.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

14

Response to MLN8237 in Pancreatic Cancer Is Not Dependent on RalA Phosphorylation

Neel, N. F., Stratford, J. K., Shinde, V., Ecsedy, J. A., Martin, T. D., Der, C. J., Yeh, J. J.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.06 MB

english, 2014

15

Sorafenib Suppresses JNK-Dependent Apoptosis through Inhibition of ZAK

Vin, H., Ching, G., Ojeda, S. S., Adelmann, C. H., Chitsazzadeh, V., Dwyer, D. W., Ma, H., Ehrenreiter, K., Baccarini, M., Ruggieri, R., Curry, J. L., Ciurea, A. M., Duvic, M., Busaidy, N. L., Tannir,

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

16

Hypoxia-Regulated Overexpression of Soluble VEGFR2 Controls Angiogenesis and Inhibits Tumor Growth

Collet, G., Lamerant-Fayel, N., Tertil, M., El Hafny-Rahbi, B., Stepniewski, J., Guichard, A., Foucault-Collet, A., Klimkiewicz, K., Petoud, S., Matejuk, A., Grillon, C., Jozkowicz, A., Dulak, J., Kie

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

17

Breaking the Invulnerability of Cancer Stem Cells: Two-Step Strategy to Kill the Stem-like Cell Subpopulation of Multiple Myeloma

Morgenroth, A., Vogg, A. T. J., Zlatopolskiy, B. D., Siluschek, M., Oedekoven, C., Mottaghy, F. M.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

18

MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-Risk Soft Tissue Sarcoma of Limbs and Trunk Wall: An ISG/GEIS Study

Martin-Broto, J., Gutierrez, A. M., Ramos, R. F., Lopez-Guerrero, J. A., Ferrari, S., Stacchiotti, S., Picci, P., Calabuig, S., Collini, P., Gambarotti, M., Bague, S., Dei Tos, A. P., Palassini, E., L

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

19

SC-60, a Dimer-Based Sorafenib Derivative, Shows a Better Anti-Hepatocellular Carcinoma Effect than Sorafenib in a Preclinical Hepatocellular Carcinoma Model

Tai, W.-T., Shiau, C.-W., Li, Y.-S., Chen, Y.-L., Chu, P.-Y., Huang, J.-W., Hsu, C.-Y., Hsu, Y.-C., Chen, P.-J., Chen, K.-F.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

20

Correction: MicroRNA Regulation of Oncolytic Adenovirus 6 for Selective Treatment of Castration-Resistant Prostate Cancer

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 150 KB

english, 2014

21

Phosphoproteomic Profiling Identifies Focal Adhesion Kinase as a Mediator of Docetaxel Resistance in Castrate-Resistant Prostate Cancer

Lee, B. Y., Hochgrafe, F., Lin, H.-M., Castillo, L., Wu, J., Raftery, M. J., Martin Shreeve, S., Horvath, L. G., Daly, R. J.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

22

Off-Target Effects of c-MET Inhibitors on Thyroid Cancer Cells

Zhou, Y., Zhao, C., Gery, S., Braunstein, G. D., Okamoto, R., Alvarez, R., Miles, S. A., Doan, N. B., Said, J. W., Gu, J., Phillip Koeffler, H.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

23

Correction: Chemotherapy Counteracts Metastatic Dissemination Induced by Antiangiogenic Treatment in Mice

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

24

Small-Molecule IAP Antagonists Sensitize Cancer Cells to TRAIL-Induced Apoptosis: Roles of XIAP and cIAPs

Finlay, D., Vamos, M., Gonzalez-Lopez, M., Ardecky, R. J., Ganji, S. R., Yuan, H., Su, Y., Cooley, T. R., Hauser, C. T., Welsh, K., Reed, J. C., Cosford, N. D. P., Vuori, K.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

25

Differential Therapeutic Effects of Anti-VEGF-A Antibody in Different Tumor Models: Implications for Choosing Appropriate Tumor Models for Drug Testing

Alishekevitz, D., Bril, R., Loven, D., Miller, V., Voloshin, T., Gingis-Velistki, S., Fremder, E., Scherer, S. J., Shaked, Y.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.91 MB

english, 2014

26

Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L.

Sun, Q., Liu, K., Shen, X., Jin, W., Jiang, L., Saeed Sheikh, M., Hu, Y., Huang, Y.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.56 MB

english, 2014

27

Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma

Qin, Z., Dai, L., Trillo-Tinoco, J., Senkal, C., Wang, W., Reske, T., Bonstaff, K., Del Valle, L., Rodriguez, P., Flemington, E., Voelkel-Johnson, C., Smith, C. D., Ogretmen, B., Parsons, C.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

28

A Message from the New Editor-in-Chief

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 228 KB

english, 2014

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

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