Volume 13; Issue 10

Molecular Cancer Therapeutics

Volume 13; Issue 10

1

BET Protein Antagonist JQ1 Is Synergistically Lethal with FLT3 Tyrosine Kinase Inhibitor (TKI) and Overcomes Resistance to FLT3-TKI in AML Cells Expressing FLT-ITD

Fiskus, W., Sharma, S., Qi, J., Shah, B., Devaraj, S. G. T., Leveque, C., Portier, B. P., Iyer, S., Bradner, J. E., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 986 KB

english, 2014

2

Piperlongumine Chemosensitizes Tumor Cells through Interaction with Cysteine 179 of I B Kinase, Leading to Suppression of NF- B-Regulated Gene Products

Han, J. G., Gupta, S. C., Prasad, S., Aggarwal, B. B.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.05 MB

english, 2014

3

Synergistic Simvastatin and Metformin Combination Chemotherapy for Osseous Metastatic Castration-Resistant Prostate Cancer

Babcook, M. A., Shukla, S., Fu, P., Vazquez, E. J., Puchowicz, M. A., Molter, J. P., Oak, C. Z., MacLennan, G. T., Flask, C. A., Lindner, D. J., Parker, Y., Daneshgari, F., Gupta, S.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

4

The CREB-Binding Protein Inhibitor ICG-001 Suppresses Pancreatic Cancer Growth

Arensman, M. D., Telesca, D., Lay, A. R., Kershaw, K. M., Wu, N., Donahue, T. R., Dawson, D. W.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 894 KB

english, 2014

5

Regulation of OSU-03012 Toxicity by ER Stress Proteins and ER Stress-Inducing Drugs

Booth, L., Roberts, J. L., Cruickshanks, N., Grant, S., Poklepovic, A., Dent, P.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

6

Inhibition of Endoglin-GIPC Interaction Inhibits Pancreatic Cancer Cell Growth

Pal, K., Pletnev, A. A., Dutta, S. K., Wang, E., Zhao, R., Baral, A., Yadav, V. K., Aggarwal, S., Krishnaswamy, S., Alkharfy, K. M., Chowdhury, S., Spaller, M. R., Mukhopadhyay, D.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

7

Nanolipolee-007, a Novel Nanoparticle-Based Drug Containing Leelamine for the Treatment of Melanoma

Gowda, R., Madhunapantula, S. V., Sharma, A., Kuzu, O. F., Robertson, G. P.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.52 MB

english, 2014

8

Temozolomide Induces the Production of Epidermal Growth Factor to Regulate MDR1 Expression in Glioblastoma Cells

Munoz, J. L., Rodriguez-Cruz, V., Greco, S. J., Nagula, V., Scotto, K. W., Rameshwar, P.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

9

Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer

Schlaepfer, I. R., Rider, L., Rodrigues, L. U., Gijon, M. A., Pac, C. T., Romero, L., Cimic, A., Sirintrapun, S. J., Glode, L. M., Eckel, R. H., Cramer, S. D.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

10

An In Vivo Antilymphatic Screen in Zebrafish Identifies Novel Inhibitors of Mammalian Lymphangiogenesis and Lymphatic-Mediated Metastasis

Astin, J. W., Jamieson, S. M. F., Eng, T. C. Y., Flores, M. V., Misa, J. P., Chien, A., Crosier, K. E., Crosier, P. S.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 3.11 MB

english, 2014

11

The CDK4/6 Inhibitor LY2835219 Overcomes Vemurafenib Resistance Resulting from MAPK Reactivation and Cyclin D1 Upregulation

Yadav, V., Burke, T. F., Huber, L., Van Horn, R. D., Zhang, Y., Buchanan, S. G., Chan, E. M., Starling, J. J., Beckmann, R. P., Peng, S.-B.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

12

Calpain-Mediated Integrin Deregulation as a Novel Mode of Action for the Anticancer Gallium Compound KP46

Jungwirth, U., Gojo, J., Tuder, T., Walko, G., Holcmann, M., Schofl, T., Nowikovsky, K., Wilfinger, N., Schoonhoven, S., Kowol, C. R., Lemmens-Gruber, R., Heffeter, P., Keppler, B. K., Berger, W.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

13

Integrated Analysis of Transcriptomes of Cancer Cell Lines and Patient Samples Reveals STK11/LKB1-Driven Regulation of cAMP Phosphodiesterase-4D

He, N., Kim, N., Song, M., Park, C., Kim, S., Park, E. Y., Yim, H. Y., Kim, K., Park, J. H., Kim, K. I., Zhang, F., Mills, G. B., Yoon, S.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

14

Redirected T-Cell Killing of Solid Cancers Targeted with an Anti-CD3/Trop-2-Bispecific Antibody Is Enhanced in Combination with Interferon-

Rossi, E. A., Rossi, D. L., Cardillo, T. M., Chang, C.-H., Goldenberg, D. M.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

15

Drug Repurposing Identifies a Synergistic Combination Therapy with Imatinib Mesylate for Gastrointestinal Stromal Tumor

Pessetto, Z. Y., Ma, Y., Hirst, J. J., von Mehren, M., Weir, S. J., Godwin, A. K.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

16

Systemic Delivery of a miR34a Mimic as a Potential Therapeutic for Liver Cancer

Daige, C. L., Wiggins, J. F., Priddy, L., Nelligan-Davis, T., Zhao, J., Brown, D.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

17

Prostate Cancer Cell Response to Paclitaxel Is Affected by Abnormally Expressed Securin PTTG1

Castilla, C., Flores, M. L., Medina, R., Perez-Valderrama, B., Romero, F., Tortolero, M., Japon, M. A., Saez, C.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 2.92 MB

english, 2014

18

BRCA2 and RAD51 Promote Double-Strand Break Formation and Cell Death in Response to Gemcitabine

Jones, R. M., Kotsantis, P., Stewart, G. S., Groth, P., Petermann, E.

Journal:

Molecular Cancer Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

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