Volume 14; Issue 11

Molecular Cancer Therapeutics

Volume 14; Issue 11

1

Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies

Calpe, S., Wagner, K., El Khattabi, M., Rutten, L., Zimberlin, C., Dolk, E., Verrips, C. T., Medema, J. P., Spits, H., Krishnadath, K. K.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 2.17 MB

english, 2015

2

Targeting Ribonucleotide Reductase M2 and NF- B Activation with Didox to Circumvent Tamoxifen Resistance in Breast Cancer

Shah, K. N., Wilson, E. A., Malla, R., Elford, H. L., Faridi, J. S.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 1.63 MB

english, 2015

3

Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo

Lopez, S., Cocco, E., Black, J., Bellone, S., Bonazzoli, E., Predolini, F., Ferrari, F., Schwab, C. L., English, D. P., Ratner, E., Silasi, D.-A., Azodi, M., Schwartz, P. E., Terranova, C., Angioli, R

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 1010 KB

english, 2015

4

AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules

Guichard, S. M., Curwen, J., Bihani, T., D'Cruz, C. M., Yates, J. W. T., Grondine, M., Howard, Z., Davies, B. R., Bigley, G., Klinowska, T., Pike, K. G., Pass, M., Chresta, C. M., Polanska, U. M., McE

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

5

A Novel Inhibitor of AKT1-PDPK1 Interaction Efficiently Suppresses the Activity of AKT Pathway and Restricts Tumor Growth In Vivo

Maemets-Allas, K., Viil, J., Jaks, V.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 2.74 MB

english, 2015

6

Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors

Seol, Y., Zhang, H., Agama, K., Lorence, N., Pommier, Y., Neuman, K. C.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 1020 KB

english, 2015

7

Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression

Teicher, B. A., Polley, E., Kunkel, M., Evans, D., Silvers, T., Delosh, R., Laudeman, J., Ogle, C., Reinhart, R., Selby, M., Connelly, J., Harris, E., Monks, A., Morris, J.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015