Volume 6; Issue 4

Molecular Cancer Therapeutics

Volume 6; Issue 4

1

Predicting gefitinib responsiveness in lung cancer by fluorescence in situ hybridization/chromogenic in situ hybridization analysis of EGFR and HER2 in biopsy and cytology specimens

Daniele, L., Macri, L., Schena, M., Dongiovanni, D., Bonello, L., Armando, E., Ciuffreda, L., Bertetto, O., Bussolati, G., Sapino, A.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 393 KB

english, 2007

2

H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation

Ewald, B., Sampath, D., Plunkett, W.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 629 KB

english, 2007

3

Liposomal curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer

Li, L., Ahmed, B., Mehta, K., Kurzrock, R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 478 KB

english, 2007

4

Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues

Sharp, S. Y., Prodromou, C., Boxall, K., Powers, M. V., Holmes, J. L., Box, G., Matthews, T. P., Cheung, K.-M. J., Kalusa, A., James, K., Hayes, A., Hardcastle, A., Dymock, B., Brough, P. A., Barril,

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 692 KB

english, 2007

5

S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells

Ray, S., Shyam, S., Fraizer, G. C., Almasan, A.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

6

Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase-mediated p53 phosphorylation and stabilization

Shi, R., Huang, Q., Zhu, X., Ong, Y.-B., Zhao, B., Lu, J., Ong, C.-N., Shen, H.-M.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 540 KB

english, 2007

7

Clofibric acid, a peroxisome proliferator-activated receptor ligand, inhibits growth of human ovarian cancer

Yokoyama, Y., Xin, B., Shigeto, T., Umemoto, M., Kasai-Sakamoto, A., Futagami, M., Tsuchida, S., Al-Mulla, F., Mizunuma, H.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

8

Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1

Baritaki, S., Huerta-Yepez, S., Sakai, T., Spandidos, D. A., Bonavida, B.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 420 KB

english, 2007

9

Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

Liu, T.-J., LaFortune, T., Honda, T., Ohmori, O., Hatakeyama, S., Meyer, T., Jackson, D., de Groot, J., Yung, W.K. A.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 673 KB

english, 2007

10

Identification of a novel inhibitor of urokinase-type plasminogen activator

Zhu, M., Gokhale, V. M., Szabo, L., Munoz, R. M., Baek, H., Bashyam, S., Hurley, L. H., Von Hoff, D. D., Han, H.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 344 KB

english, 2007

11

Uncommon tumors and exceptional therapies: paradox or paradigm?

Braiteh, F., Kurzrock, R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

12

The randomized discontinuation trial: a phase II design to assess growth-inhibitory agents

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 118 KB

english, 2007

13

Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity

Ding, W.-Q., Lind, S. E.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

14

Use of fluorescent labeled anti-epidermal growth factor receptor antibody to image head and neck squamous cell carcinoma xenografts

Rosenthal, E. L., Kulbersh, B. D., King, T., Chaudhuri, T. R., Zinn, K. R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 641 KB

english, 2007

15

The RET oncogene is a critical component of transcriptional programs associated with retinoic acid-induced differentiation in neuroblastoma

Oppenheimer, O., Cheung, N.-K., Gerald, W. L.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 712 KB

english, 2007

16

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer

Zhang, Q., Bhola, N. E., Lui, V. W. Y., Siwak, D. R., Thomas, S. M., Gubish, C. T., Siegfried, J. M., Mills, G. B., Shin, D., Grandis, J. R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 687 KB

english, 2007

17

Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival

Wilsker, D., Bunz, F.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

18

Tumor-stroma interactions in pancreatic ductal adenocarcinoma

Mahadevan, D., Von Hoff, D. D.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 448 KB

english, 2007

19

Novel xenograft model expressing human hepatocyte growth factor shows ligand-dependent growth of c-Met-expressing tumors

Francone, T. D., Landmann, R. G., Chen, C.-T., Sun, M. Y., Kuntz, E. J., Zeng, Z., Dematteo, R. P., Paty, P. B., Weiser, M. R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 273 KB

english, 2007

20

1 ,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells

Ben-Shoshan, M., Amir, S., Dang, D. T., Dang, L. H., Weisman, Y., Mabjeesh, N. J.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 379 KB

english, 2007

21

Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib

Pyrko, P., Kardosh, A., Liu, Y.-T., Soriano, N., Xiong, W., Chow, R. H., Uddin, J., Petasis, N. A., Mircheff, A. K., Farley, R. A., Louie, S. G., Chen, T. C., Schonthal, A. H.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 724 KB

english, 2007

22

Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function

Schafer-Hales, K., Iaconelli, J., Snyder, J. P., Prussia, A., Nettles, J. H., El-Naggar, A., Khuri, F. R., Giannakakou, P., Marcus, A. I.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 960 KB

english, 2007

23

Tumor cytotoxicity and endothelial Rac inhibition induced by TNP-470 in anaplastic thyroid cancer

Nahari, D., Satchi-Fainaro, R., Chen, M., Mitchell, I., Task, L. B., Liu, Z., Kihneman, J., Carroll, A. B., Terada, L. S., Nwariaku, F. E.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 556 KB

english, 2007

24

Molecular mechanisms of the chemopreventive effect on hepatocellular carcinoma development in Mdr2 knockout mice

Katzenellenbogen, M., Mizrahi, L., Pappo, O., Klopstock, N., Olam, D., Barash, H., Domany, E., Galun, E., Goldenberg, D.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 454 KB

english, 2007

25

Loss of mitochondrial membrane potential is inhibited by bombesin in etoposide-induced apoptosis in PC-3 prostate carcinoma cells

Salido, M., Gonzalez, J. L., Vilches, J.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 388 KB

english, 2007

26

MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival

Demuth, T., Reavie, L. B., Rennert, J. L., Nakada, M., Nakada, S., Hoelzinger, D. B., Beaudry, C. E., Henrichs, A. N., Anderson, E. M., Berens, M. E.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 538 KB

english, 2007

27

Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate

Cutts, S. M., Swift, L. P., Pillay, V., Forrest, R. A., Nudelman, A., Rephaeli, A., Phillips, D. R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 337 KB

english, 2007

28

Levels of p27kip1 determine Aplidin sensitivity

Moneo, V., Serelde, B. G., Leal, J. F.M., Blanco-Aparicio, C., Diaz-Uriarte, R., Aracil, M., Tercero, J. C., Jimeno, J., Carnero, A.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

29

Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells

De los Santos, M., Zambrano, A., Aranda, A.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 439 KB

english, 2007

30

Inhibition of nuclear factor- B augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation

Oida, Y., Gopalan, B., Miyahara, R., Branch, C. D., Chiao, P., Chada, S., Ramesh, R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 604 KB

english, 2007

31

Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic

Herman-Antosiewicz, A., Stan, S. D., Hahm, E.-R., Xiao, D., Singh, S. V.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 701 KB

english, 2007

32

Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells

Nam, S., Williams, A., Vultur, A., List, A., Bhalla, K., Smith, D., Lee, F. Y., Jove, R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

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