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Volume 7; Issue 10
Main
Molecular Cancer Therapeutics
Volume 7; Issue 10
Molecular Cancer Therapeutics
Volume 7; Issue 10
1
Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines
Galmarini, C. M.
,
Warren, G.
,
Kohli, E.
,
Zeman, A.
,
Mitin, A.
,
Vinogradov, S. V.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 206 KB
Your tags:
english, 2008
2
Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes
Lei, P.
,
Abdelrahim, M.
,
Cho, S. D.
,
Liu, X.
,
Safe, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 777 KB
Your tags:
english, 2008
3
Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma
Payne, C. A.
,
Maleki, S.
,
Messina, M.
,
O'Sullivan, M. G.
,
Stone, G.
,
Hall, N. R.
,
Parkinson, J. F.
,
Wheeler, H. R.
,
Cook, R. J.
,
Biggs, M. T.
,
Little, N. S.
,
Teo, C.
,
Robinson, B. G.
,
McDonald, K. L.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 329 KB
Your tags:
english, 2008
4
Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition
Fischer, H.
,
Taylor, N.
,
Allerstorfer, S.
,
Grusch, M.
,
Sonvilla, G.
,
Holzmann, K.
,
Setinek, U.
,
Elbling, L.
,
Cantonati, H.
,
Grasl-Kraupp, B.
,
Gauglhofer, C.
,
Marian, B.
,
Micksche, M.
,
Berger, W.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 707 KB
Your tags:
english, 2008
5
Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling
Wilhelm, S. M.
,
Adnane, L.
,
Newell, P.
,
Villanueva, A.
,
Llovet, J. M.
,
Lynch, M.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 932 KB
Your tags:
english, 2008
6
Bone marrow and tumor cell colony-forming units and human tumor xenograft efficacy of noncamptothecin and camptothecin topoisomerase I inhibitors
Kurtzberg, L. S.
,
Battle, T.
,
Rouleau, C.
,
Bagley, R. G.
,
Agata, N.
,
Yao, M.
,
Schmid, S.
,
Roth, S.
,
Crawford, J.
,
Krumbholz, R.
,
Ewesuedo, R.
,
Yu, X.-J.
,
Wang, F.
,
LaVoie, E. J.
,
Teicher, B. A.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 357 KB
Your tags:
english, 2008
7
Treatment of hepatocellular carcinoma in mice with PE38KDEL type I mutant-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with humanized SM5-1 F(ab') fragments
Gao, J.
,
Kou, G.
,
Chen, H.
,
Wang, H.
,
Li, B.
,
Lu, Y.
,
Zhang, D.
,
Wang, S.
,
Hou, S.
,
Qian, W.
,
Dai, J.
,
Zhao, J.
,
Zhong, Y.
,
Guo, Y.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 323 KB
Your tags:
english, 2008
8
Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
Gu, H.
,
Wang, X.
,
Rao, S.
,
Wang, J.
,
Zhao, J.
,
Ren, F. L.
,
Mu, R.
,
Yang, Y.
,
Qi, Q.
,
Liu, W.
,
Lu, N.
,
Ling, H.
,
You, Q.
,
Guo, Q.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 402 KB
Your tags:
english, 2008
9
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
Basak, S.
,
Pookot, D.
,
Noonan, E. J.
,
Dahiya, R.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 371 KB
Your tags:
english, 2008
10
15-deoxy- 12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription
Su, R.-Y.
,
Chi, K.-H.
,
Huang, D.-Y.
,
Tai, M.-H.
,
Lin, W.-W.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 667 KB
Your tags:
english, 2008
11
Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin
Peklak-Scott, C.
,
Smitherman, P. K.
,
Townsend, A. J.
,
Morrow, C. S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 550 KB
Your tags:
english, 2008
12
Class I -tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions
Liaw, T. Y.E.
,
Salam, N. K.
,
McKay, M. J.
,
Cunningham, A. M.
,
Hibbs, D. E.
,
Kavallaris, M.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 537 KB
Your tags:
english, 2008
13
Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor
Hodgson, M. C.
,
Shen, H. C.
,
Hollenberg, A. N.
,
Balk, S. P.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 438 KB
Your tags:
english, 2008
14
A genomic approach to identify molecular pathways associated with chemotherapy resistance
Riedel, R. F.
,
Porrello, A.
,
Pontzer, E.
,
Chenette, E. J.
,
Hsu, D. S.
,
Balakumaran, B.
,
Potti, A.
,
Nevins, J.
,
Febbo, P. G.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 703 KB
Your tags:
english, 2008
15
Cisplatin abrogates the geldanamycin-induced heat shock response
McCollum, A. K.
,
Lukasiewicz, K. B.
,
TenEyck, C. J.
,
Lingle, W. L.
,
Toft, D. O.
,
Erlichman, C.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 387 KB
Your tags:
english, 2008
16
Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition
Yagi, H.
,
Yotsumoto, F.
,
Miyamoto, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 813 KB
Your tags:
english, 2008
17
Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor- B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis
Kunnumakkara, A. B.
,
Ichikawa, H.
,
Anand, P.
,
Mohankumar, C. J.
,
Hema, P. S.
,
Nair, M. S.
,
Aggarwal, B. B.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 666 KB
Your tags:
english, 2008
18
Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance
Bewry, N. N.
,
Nair, R. R.
,
Emmons, M. F.
,
Boulware, D.
,
Pinilla-Ibarz, J.
,
Hazlehurst, L. A.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 366 KB
Your tags:
english, 2008
19
Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanism
Priego, S.
,
Feddi, F.
,
Ferrer, P.
,
Mena, S.
,
Benlloch, M.
,
Ortega, A.
,
Carretero, J.
,
Obrador, E.
,
Asensi, M.
,
Estrela, J. M.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 383 KB
Your tags:
english, 2008
20
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion
Saunders, L. P.
,
Ouellette, A.
,
Bandle, R.
,
Chang, W. C.
,
Zhou, H.
,
Misra, R. N.
,
De La Cruz, E. M.
,
Braddock, D. T.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 563 KB
Your tags:
english, 2008
21
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines
Lorenzi, P. L.
,
Llamas, J.
,
Gunsior, M.
,
Ozbun, L.
,
Reinhold, W. C.
,
Varma, S.
,
Ji, H.
,
Kim, H.
,
Hutchinson, A. A.
,
Kohn, E. C.
,
Goldsmith, P. K.
,
Birrer, M. J.
,
Weinstein, J. N.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 357 KB
Your tags:
english, 2008
22
Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions
Rosato, R. R.
,
Almenara, J. A.
,
Maggio, S. C.
,
Coe, S.
,
Atadja, P.
,
Dent, P.
,
Grant, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 736 KB
Your tags:
english, 2008
23
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
Fernandez de Mattos, S.
,
Villalonga, P.
,
Clardy, J.
,
Lam, E. W-F.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 378 KB
Your tags:
english, 2008
24
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts
Sarup, J.
,
Jin, P.
,
Turin, L.
,
Bai, X.
,
Beryt, M.
,
Brdlik, C.
,
Higaki, J. N.
,
Jorgensen, B.
,
Lau, F. W.
,
Lindley, P.
,
Liu, J.
,
Ni, I.
,
Rozzelle, J.
,
Kumari, R.
,
Watson, S. A.
,
Zhang, J.
,
Shepard, H. M
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 409 KB
Your tags:
english, 2008
25
Long-term progression and therapeutic response of visceral metastatic disease non-invasively monitored in mouse urine using -human choriogonadotropin secreting tumor cell lines
Francia, G.
,
Emmenegger, U.
,
Lee, C. R.
,
Shaked, Y.
,
Folkins, C.
,
Mossoba, M.
,
Medin, J. A.
,
Man, S.
,
Zhu, Z.
,
Witte, L.
,
Kerbel, R. S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 578 KB
Your tags:
english, 2008
26
ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo
Ackler, S.
,
Xiao, Y.
,
Mitten, M. J.
,
Foster, K.
,
Oleksijew, A.
,
Refici, M.
,
Schlessinger, S.
,
Wang, B.
,
Chemburkar, S. R.
,
Bauch, J.
,
Tse, C.
,
Frost, D. J.
,
Fesik, S. W.
,
Rosenberg, S. H.
,
Elmore, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 584 KB
Your tags:
english, 2008
27
Identification and characterization of small-molecule inhibitors of hepsin
Chevillet, J. R.
,
Park, G. J.
,
Bedalov, A.
,
Simon, J. A.
,
Vasioukhin, V. I.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 336 KB
Your tags:
english, 2008
28
Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer
Song, D.
,
Chaerkady, R.
,
Tan, A. C.
,
Garcia-Garcia, E.
,
Nalli, A.
,
Suarez-Gauthier, A.
,
Lopez-Rios, F.
,
Zhang, X. F.
,
Solomon, A.
,
Tong, J.
,
Read, M.
,
Fritz, C.
,
Jimeno, A.
,
Pandey, A.
,
Hidalgo, M.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 785 KB
Your tags:
english, 2008
29
EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance
Zhang, Y.
,
Linn, D.
,
Liu, Z.
,
Melamed, J.
,
Tavora, F.
,
Young, C. Y.
,
Burger, A. M.
,
Hamburger, A. W.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 866 KB
Your tags:
english, 2008
30
Curcumin suppresses constitutive activation of nuclear factor- B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines
Hussain, A. R.
,
Ahmed, M.
,
Al-Jomah, N. A.
,
Khan, A. S.
,
Manogaran, P.
,
Sultana, M.
,
Abubaker, J.
,
Platanias, L. C.
,
Al-Kuraya, K. S.
,
Uddin, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 529 KB
Your tags:
english, 2008
31
Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 phosphorylation
Lu, Y.
,
Nie, D.
,
Witt, W. T.
,
Chen, Q.
,
Shen, M.
,
Xie, H.
,
Lai, L.
,
Dai, Y.
,
Zhang, J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 515 KB
Your tags:
english, 2008
32
Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway
Co, N. N.
,
Tsang, W. P.
,
Wong, T. W.L.
,
Cheung, H. H.
,
Tsang, T. Y.
,
Kong, S. K.
,
Kwok, T. T.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 1.14 MB
Your tags:
english, 2008
33
Distribution and bioactivity of the Ret-specific D4 aptamer in three-dimensional collagen gel cultures
Vento, M. T.
,
Iuorio, M.
,
Netti, P. A.
,
Duconge, F.
,
Tavitian, B.
,
Franciscis, V.
,
Cerchia, L.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 600 KB
Your tags:
english, 2008
34
Therapeutic efficacy of soluble receptor activator of nuclear factor- B-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma
Lamoureux, F.
,
Picarda, G.
,
Rousseau, J.
,
Gourden, C.
,
Battaglia, S.
,
Charrier, C.
,
Pitard, B.
,
Heymann, D.
,
Redini, F.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 792 KB
Your tags:
english, 2008
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