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Volume 7; Issue 6
Main
Molecular Cancer Therapeutics
Volume 7; Issue 6
Molecular Cancer Therapeutics
Volume 7; Issue 6
1
5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy
Bourre, L.
,
Giuntini, F.
,
Eggleston, I. M.
,
Wilson, M.
,
MacRobert, A. J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 401 KB
Your tags:
english, 2008
2
Human -defensin-1 inhibits growth of human lung adenocarcinoma xenograft in nude mice
Xu, N.
,
Wang, Y.-s.
,
Pan, W.-b.
,
Xiao, B.
,
Wen, Y.-j.
,
Chen, X.-c.
,
Chen, L.-j.
,
Deng, H.-x.
,
You, J.
,
Kan, B.
,
Fu, A-f.
,
Li, D.
,
Zhao, X.
,
Wei, Y.-q.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 576 KB
Your tags:
english, 2008
3
Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
Weyergang, A.
,
Kaalhus, O.
,
Berg, K.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 407 KB
Your tags:
english, 2008
4
Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198
LaVallee, T. M.
,
Burke, P. A.
,
Swartz, G. M.
,
Hamel, E.
,
Agoston, G. E.
,
Shah, J.
,
Suwandi, L.
,
Hanson, A. D.
,
Fogler, W. E.
,
Sidor, C. F.
,
Treston, A. M.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 527 KB
Your tags:
english, 2008
5
In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy
Melancon, M. P.
,
Lu, W.
,
Yang, Z.
,
Zhang, R.
,
Cheng, Z.
,
Elliot, A. M.
,
Stafford, J.
,
Olson, T.
,
Zhang, J. Z.
,
Li, C.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 801 KB
Your tags:
english, 2008
6
Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage
Yan, Y.
,
Su, X.
,
Liang, Y.
,
Zhang, J.
,
Shi, C.
,
Lu, Y.
,
Gu, L.
,
Fu, L.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 581 KB
Your tags:
english, 2008
7
Anticancer drugs affect the alternative splicing of Bcl-x and other human apoptotic genes
Shkreta, L.
,
Froehlich, U.
,
Paquet, E. R.
,
Toutant, J.
,
Elela, S. A.
,
Chabot, B.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 1.08 MB
Your tags:
english, 2008
8
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer
Shangary, S.
,
Ding, K.
,
Qiu, S.
,
Nikolovska-Coleska, Z.
,
Bauer, J. A.
,
Liu, M.
,
Wang, G.
,
Lu, Y.
,
McEachern, D.
,
Bernard, D.
,
Bradford, C. R.
,
Carey, T. E.
,
Wang, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 1.10 MB
Your tags:
english, 2008
9
DNA vaccination with CD44 variant isoform reduces mammary tumor local growth and lung metastasis
Wallach-Dayan, S. B.
,
Rubinstein, A. M.
,
Hand, C.
,
Breuer, R.
,
Naor, D.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 348 KB
Your tags:
english, 2008
10
Potent synergy of dual antitumor peptides for growth suppression of human glioblastoma cell lines
Kondo, E.
,
Tanaka, T.
,
Miyake, T.
,
Ichikawa, T.
,
Hirai, M.
,
Adachi, M.
,
Yoshikawa, K.
,
Ichimura, K.
,
Ohara, N.
,
Moriwaki, A.
,
Date, I.
,
Ueda, R.
,
Yoshino, T.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 724 KB
Your tags:
english, 2008
11
Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas
Piao, W.
,
Wang, Y.
,
Adachi, Y.
,
Yamamoto, H.
,
Li, R.
,
Imsumran, A.
,
Li, H.
,
Maehata, T.
,
Ii, M.
,
Arimura, Y.
,
Lee, C.-T.
,
Shinomura, Y.
,
Carbone, D. P.
,
Imai, K.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 752 KB
Your tags:
english, 2008
12
Fasudil-induced hypoxia-inducible factor-1 degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells
Takata, K.
,
Morishige, K.-i.
,
Takahashi, T.
,
Hashimoto, K.
,
Tsutsumi, S.
,
Yin, L.
,
Ohta, T.
,
Kawagoe, J.
,
Takahashi, K.
,
Kurachi, H.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 508 KB
Your tags:
english, 2008
13
Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells
Li, C.
,
Li, R.
,
Grandis, J. R.
,
Johnson, D. E.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 727 KB
Your tags:
english, 2008
14
Generation of adenovirus-mediated anti-CD20 antibody and its effect on B-cell deletion in mice and nonhuman primate cynomolgus monkey
Chen, J.
,
Su, C.
,
Lu, Q.
,
Shi, W.
,
Zhang, Q.
,
Wang, X.
,
Long, J.
,
Yang, Q.
,
Li, L.
,
Jia, X.
,
Wang, J.
,
Da, W.
,
Liu, X.
,
Wu, M.
,
Qian, Q.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 306 KB
Your tags:
english, 2008
15
Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid
Domhan, S.
,
Muschal, S.
,
Schwager, C.
,
Morath, C.
,
Wirkner, U.
,
Ansorge, W.
,
Maercker, C.
,
Zeier, M.
,
Huber, P. E.
,
Abdollahi, A.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 936 KB
Your tags:
english, 2008
16
Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBP
Wu, C.-C.
,
Lin, J.-C.
,
Yang, S.-C.
,
Lin, C.-W.
,
Chen, J. J.W.
,
Shih, J.-Y.
,
Hong, T.-M.
,
Yang, P.-C.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 630 KB
Your tags:
english, 2008
17
In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation
Ikediobi, O. N.
,
Reimers, M.
,
Durinck, S.
,
Blower, P. E.
,
Futreal, A. P.
,
Stratton, M. R.
,
Weinstein, J. N.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 355 KB
Your tags:
english, 2008
18
A novel triple-regulated oncolytic adenovirus carrying p53 gene exerts potent antitumor efficacy on common human solid cancers
Wang, X.
,
Su, C.
,
Cao, H.
,
Li, K.
,
Chen, J.
,
Jiang, L.
,
Zhang, Q.
,
Wu, X.
,
Jia, X.
,
Liu, Y.
,
Wang, W.
,
Liu, X.
,
Wu, M.
,
Qian, Q.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 251 KB
Your tags:
english, 2008
19
-Catenin overrides Src-dependent activation of -catenin oncogenic signaling
Inge, L. J.
,
Rajasekaran, S. A.
,
Wolle, D.
,
Barwe, S. P.
,
Ryazantsev, S.
,
Ewing, C. M.
,
Isaacs, W. B.
,
Rajasekaran, A. K.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 656 KB
Your tags:
english, 2008
20
Biodistribution and kinetics of the novel selective oncolytic adenovirus M1 after systemic administration
Huang, X.
,
Zhuang, L.
,
Cao, Y.
,
Gao, Q.
,
Han, Z.
,
Tang, D.
,
Xing, H.
,
Wang, W.
,
Lu, Y.
,
Xu, G.
,
Wang, S.
,
Zhou, J.
,
Ma, D.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 575 KB
Your tags:
english, 2008
21
Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines
Wangpaichitr, M.
,
Savaraj, N.
,
Maher, J.
,
Kurtoglu, M.
,
Lampidis, T. J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 687 KB
Your tags:
english, 2008
22
Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer
Ali, S.
,
Banerjee, S.
,
Ahmad, A.
,
El-Rayes, B. F.
,
Philip, P. A.
,
Sarkar, F. H.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 614 KB
Your tags:
english, 2008
23
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies
Garcia, J. A.
,
Danielpour, D.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 302 KB
Your tags:
english, 2008
24
Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins
Huang, M.
,
Miao, Z.-H.
,
Zhu, H.
,
Cai, Y.-J.
,
Lu, W.
,
Ding, J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 798 KB
Your tags:
english, 2008
25
Antitumor effect of a transducible fusogenic peptide releasing multiple proapoptotic peptides by caspase-3
Kwon, M.-K.
,
Nam, J.-O.
,
Park, R.-W.
,
Lee, B.-H.
,
Park, J.-Y.
,
Byun, Y.-R.
,
Kim, S.-Y.
,
Kwon, I.-C.
,
Kim, I.-S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 641 KB
Your tags:
english, 2008
26
Targeting IL-13R 2-positive cancer with a novel recombinant immunotoxin composed of a single-chain antibody and mutated Pseudomonas exotoxin
Kioi, M.
,
Seetharam, S.
,
Puri, R. K.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 423 KB
Your tags:
english, 2008
27
Eps8 decreases chemosensitivity and affects survival of cervical cancer patients
Chen, Y.-J.
,
Shen, M.-R.
,
Chen, Y.-J.
,
Maa, M.-C.
,
Leu, T.-H.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 656 KB
Your tags:
english, 2008
28
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells
Muscolini, M.
,
Cianfrocca, R.
,
Sajeva, A.
,
Mozzetti, S.
,
Ferrandina, G.
,
Costanzo, A.
,
Tuosto, L.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 515 KB
Your tags:
english, 2008
29
KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling
Feng, R.
,
Ma, H.
,
Hassig, C. A.
,
Payne, J. E.
,
Smith, N. D.
,
Mapara, M. Y.
,
Hager, J. H.
,
Lentzsch, S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 667 KB
Your tags:
english, 2008
30
STAT3 inhibition in prostate and pancreatic cancer lines by STAT3 binding sequence oligonucleotides: differential activity between 5' and 3' ends
Lewis, H. D.
,
Winter, A.
,
Murphy, T. F.
,
Tripathi, S.
,
Pandey, V. N.
,
Barton, B. E.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 376 KB
Your tags:
english, 2008
31
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth
Yan, Z.
,
Zou, H.
,
Tian, F.
,
Grandis, J. R.
,
Mixson, A. J.
,
Lu, P. Y.
,
Li, L.-Y.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 485 KB
Your tags:
english, 2008
32
Anti-integrin monoclonal antibody CNTO 95 enhances the therapeutic efficacy of fractionated radiation therapy in vivo
Ning, S.
,
Nemeth, J. A.
,
Hanson, R. L.
,
Forsythe, K.
,
Knox, S. J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 464 KB
Your tags:
english, 2008
33
17-Acetoxyjolkinolide B irreversibly inhibits I B kinase and induces apoptosis of tumor cells
Yan, S.-S.
,
Li, Y.
,
Wang, Y.
,
Shen, S.-S.
,
Gu, Y.
,
Wang, H.-B.
,
Qin, G.-W.
,
Yu, Q.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 426 KB
Your tags:
english, 2008
34
Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma
Hegde, G. V.
,
Munger, C. M.
,
Emanuel, K.
,
Joshi, A. D.
,
Greiner, T. C.
,
Weisenburger, D. D.
,
Vose, J. M.
,
Joshi, S. S.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 687 KB
Your tags:
english, 2008
35
Arsenic trioxide decreases AKT protein in a caspase-dependent manner
Mann, K. K.
,
Colombo, M.
,
Miller, W. H.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 425 KB
Your tags:
english, 2008
36
Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis
Singleton, P. A.
,
Garcia, J. G.N.
,
Moss, J.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 584 KB
Your tags:
english, 2008
37
Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
Zhai, D.
,
Jin, C.
,
Shiau, C.-w.
,
Kitada, S.
,
Satterthwait, A. C.
,
Reed, J. C.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 412 KB
Your tags:
english, 2008
38
Pinitol targets nuclear factor- B activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis
Sethi, G.
,
Ahn, K. S.
,
Sung, B.
,
Aggarwal, B. B.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 429 KB
Your tags:
english, 2008
39
Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models
Liu, S.
,
Cheng, H.
,
Kwan, W.
,
Lubieniecka, J. M.
,
Nielsen, T. O.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 452 KB
Your tags:
english, 2008
40
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C inhibitor, in non-small cell lung cancer cells
Morgillo, F.
,
Martinelli, E.
,
Troiani, T.
,
Laus, G.
,
Pepe, S.
,
Gridelli, C.
,
Ciardiello, F.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 736 KB
Your tags:
english, 2008
41
Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor-mediated transcription
You, L.
,
Xu, Z.
,
Punchihewa, C.
,
Jablons, D. M.
,
Fujii, N.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 258 KB
Your tags:
english, 2008
42
Recombinant, refolded tetrameric p53 and gonadotropin-releasing hormone-p53 slow proliferation and induce apoptosis in p53-deficient cancer cells
LaFevre-Bernt, M.
,
Wu, S.
,
Lin, X.
Journal:
Molecular Cancer Therapeutics
Year:
2008
Language:
english
File:
PDF, 536 KB
Your tags:
english, 2008
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