Volume 8; Issue 12

Molecular Cancer Therapeutics

Volume 8; Issue 12

1

Angiotensin type 2 receptor-mediated apoptosis of human prostate cancer cells

Li, H., Qi, Y., Li, C., Braseth, L. N., Gao, Y., Shabashvili, A. E., Katovich, M. J., Sumners, C.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 748 KB

english, 2009

2

Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1 /Sp4

Tsai, W.-B., Aiba, I., Lee, S.-y., Feun, L., Savaraj, N., Kuo, M. T.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 551 KB

english, 2009

3

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

Tinsley, H. N., Gary, B. D., Keeton, A. B., Zhang, W., Abadi, A. H., Reynolds, R. C., Piazza, G. A.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 449 KB

english, 2009

4

Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D

Ballot, C., Kluza, J., Martoriati, A., Nyman, U., Formstecher, P., Joseph, B., Bailly, C., Marchetti, P.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 533 KB

english, 2009

5

Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of -tubulin at Cys 12 and suppression of microtubule dynamics

Xu, W., Xi, B., Wu, J., An, H., Zhu, J., Abassi, Y., Feinstein, S. C., Gaylord, M., Geng, B., Yan, H., Fan, W., Sui, M., Wang, X., Xu, X.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 1.42 MB

english, 2009

6

Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity

Appierto, V., Tiberio, P., Cavadini, E., Casalini, P., Cappelletti, G., Formelli, F.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 601 KB

english, 2009

7

Correction: Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 304 KB

english, 2009

8

G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells

Zhou, W.-J., Deng, R., Zhang, X.-Y., Feng, G.-K., Gu, L.-Q., Zhu, X.-F.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 751 KB

english, 2009

9

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo

Buchanan, S. G., Hendle, J., Lee, P. S., Smith, C. R., Bounaud, P.-Y., Jessen, K. A., Tang, C. M., Huser, N. H., Felce, J. D., Froning, K. J., Peterman, M. C., Aubol, B. E., Gessert, S. F., Sauder, J.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 646 KB

english, 2009

10

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and paclitaxel have cooperative in vivo effects against glioblastoma multiforme cells

Dorsey, J. F., Mintz, A., Tian, X., Dowling, M. L., Plastaras, J. P., Dicker, D. T., Kao, G. D., El-Deiry, W. S.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 724 KB

english, 2009

11

In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts

Williams, K. J., Albertella, M. R., Fitzpatrick, B., Loadman, P. M., Shnyder, S. D., Chinje, E. C., Telfer, B. A., Dunk, C. R., Harris, P. A., Stratford, I. J.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 779 KB

english, 2009

12

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

Carboni, J. M., Wittman, M., Yang, Z., Lee, F., Greer, A., Hurlburt, W., Hillerman, S., Cao, C., Cantor, G. H., Dell-John, J., Chen, C., Discenza, L., Menard, K., Li, A., Trainor, G., Vyas, D., Kramer

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 716 KB

english, 2009

13

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells

Sun, F., Chan, E., Wu, Z., Yang, X., Marquez, V. E., Yu, Q.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 817 KB

english, 2009

14

A novel two-step transcriptional activation system for gene therapy directed toward epithelial cells

Arendt, M. L., Nasir, L., Morgan, I. M.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 438 KB

english, 2009

15

Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase

Gao, Y., Fotovati, A., Lee, C., Wang, M., Cote, G., Guns, E., Toyota, B., Faury, D., Jabado, N., Dunn, S. E.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 679 KB

english, 2009

16

Acknowledgment to Reviewers/Volume 8

Journal:

Molecular Cancer Therapeutics

Year:

2009

File:

PDF, 116 KB

2009

17

Basal c-Jun NH2-terminal protein kinase activity is essential for survival and proliferation of T-cell acute lymphoblastic leukemia cells

Cui, J., Wang, Q., Wang, J., Lv, M., Zhu, N., Li, Y., Feng, J., Shen, B., Zhang, J.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 813 KB

english, 2009

18

The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo

Douglas, M., Lim, A. R., Porter, J. R., West, K., Pink, M. M., Ge, J., Wylie, A. A., Tibbits, T. T., Biggs, K., Curtis, M., Palombella, V. J., Adams, J., Fritz, C. C., Normant, E.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 538 KB

english, 2009

19

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo

Vlaming, M. L. H., van Esch, A., Pala, Z., Wagenaar, E., van de Wetering, K., van Tellingen, O., Schinkel, A. H.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

20

Bim-targeted cancer therapy: A link between drug action and underlying molecular changes

Akiyama, T., Dass, C. R., Choong, P. F.M.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 494 KB

english, 2009

21

The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models

Williamson, M. J., Silva, M. D., Terkelsen, J., Robertson, R., Yu, L., Xia, C., Hatsis, P., Bannerman, B., Babcock, T., Cao, Y., Kupperman, E.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 631 KB

english, 2009

22

Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer

Bao, R., Lai, C.-J., Wang, D.-G., Qu, H., Yin, L., Zifcak, B., Tao, X., Wang, J., Atoyan, R., Samson, M., Forrester, J., Xu, G.-X., DellaRocca, S., Borek, M., Zhai, H.-X., Cai, X., Qian, C.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 703 KB

english, 2009

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