Volume 9; Issue 4

Molecular Cancer Therapeutics

Volume 9; Issue 4

1

Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

Temmink, O. H., Bijnsdorp, I. V., Prins, H. J., Losekoot, N., Adema, A. D., Smid, K., Honeywell, R. J., Ylstra, B., Eijk, P. P., Fukushima, M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 430 KB

english, 2010

2

Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins

Prasad, S., Ravindran, J., Sung, B., Pandey, M. K., Aggarwal, B. B.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

3

A Molecularly Targeted Theranostic Probe for Ovarian Cancer

Chen, W., Bardhan, R., Bartels, M., Perez-Torres, C., Pautler, R. G., Halas, N. J., Joshi, A.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 533 KB

english, 2010

4

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

Peck, B., Chen, C. Y., Ho, K. K., Di Fruscia, P., Myatt, S. S., Coombes, R. C., Fuchter, M. J., Hsiao, C. D., Lam, E. W. F.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1004 KB

english, 2010

5

Phospholipase A2 Activity of Peroxiredoxin 6 Promotes Invasion and Metastasis of Lung Cancer Cells

Ho, J. N., Lee, S. B., Lee, S. S., Yoon, S. H., Kang, G. Y., Hwang, S. G., Um, H. D.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 840 KB

english, 2010

6

Vinblastine Induces Acute, Cell Cycle Phase-Independent Apoptosis in Some Leukemias and Lymphomas and Can Induce Acute Apoptosis in Others when Mcl-1 Is Suppressed

Salerni, B. L., Bates, D. J., Albershardt, T. C., Lowrey, C. H., Eastman, A.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 517 KB

english, 2010

7

Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by Nanoparticle Albumin-Bound-Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

Cirstea, D., Hideshima, T., Rodig, S., Santo, L., Pozzi, S., Vallet, S., Ikeda, H., Perrone, G., Gorgun, G., Patel, K., Desai, N., Sportelli, P., Kapoor, S., Vali, S., Mukherjee, S., Munshi, N. C., An

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

8

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

Yang, F., Brown, C., Buettner, R., Hedvat, M., Starr, R., Scuto, A., Schroeder, A., Jensen, M., Jove, R.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 842 KB

english, 2010

9

Erythropoietin and Ovarian Cancer - Response

Solar, P., Koval, J., Mikes, J., Kleban, J., Solarova, Z., Lazur, J., Hodorova, I., Fedorocko, P., Sytkowski, A. J.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 114 KB

english, 2010

10

-Ionone Enhances TRAIL-Induced Apoptosis in Hepatocellular Carcinoma Cells through Sp1-Dependent Upregulation of DR5 and Downregulation of NF- B Activity

Kim, M. O., Moon, D. O., Kang, C. H., Kwon, T. K., Choi, Y. H., Kim, G. Y.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 979 KB

english, 2010

11

Treatment with Panobinostat Induces Glucose-Regulated Protein 78 Acetylation and Endoplasmic Reticulum Stress in Breast Cancer Cells

Rao, R., Nalluri, S., Kolhe, R., Yang, Y., Fiskus, W., Chen, J., Ha, K., Buckley, K. M., Balusu, R., Coothankandaswamy, V., Joshi, A., Atadja, P., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 941 KB

english, 2010

12

Natural Immunity Enhances the Activity of a DR5 Agonistic Antibody and Carboplatin in the Treatment of Ovarian Cancer

El-Gazzar, A., Perco, P., Eckelhart, E., Anees, M., Sexl, V., Mayer, B., Liu, Y., Mikulits, W., Horvat, R., Pangerl, T., Zheng, D., Krainer, M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

13

Erythropoietin Receptor in Ovarian Cancer Cells - Letter

Swift, S. E., Elliott, S., Sinclair, A. M., Begley, C. G.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

14

Correction: Tumor Necrosis Factor Deficiency Inhibits Mammary Tumorigenesis and a Tumor Necrosis Factor Neutralizing Antibody Decreases Mammary Tumor Growth in neu/erbB2 Transgenic Mice

Journal:

Molecular Cancer Therapeutics

Year:

2010

File:

PDF, 39 KB

2010

15

Pretargeted Immuno-Positron Emission Tomography Imaging of Carcinoembryonic Antigen-Expressing Tumors with a Bispecific Antibody and a 68Ga- and 18F-Labeled Hapten Peptide in Mice with Human Tumor Xenografts

Schoffelen, R., Sharkey, R. M., Goldenberg, D. M., Franssen, G., McBride, W. J., Rossi, E. A., Chang, C. H., Laverman, P., Disselhorst, J. A., Eek, A., van der Graaf, W. T. A., Oyen, W. J. G., Boerman

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

16

Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800

Massey, A. J., Schoepfer, J., Brough, P. A., Brueggen, J., Chene, P., Drysdale, M. J., Pfaar, U., Radimerski, T., Ruetz, S., Schweitzer, A., Wood, M., Garcia-Echeverria, C., Jensen, M. R.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

17

Gene Expression Signatures as a Guide to Treatment Strategies for In-Transit Metastatic Melanoma

Augustine, C. K., Jung, S. H., Sohn, I., Yoo, J. S., Yoshimoto, Y., Olson, J. A., Friedman, H. S., Ali-Osman, F., Tyler, D. S.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

18

Subcellular Distribution of a Fluorescence-Labeled Combi-Molecule Designed to Block Epidermal Growth Factor Receptor Tyrosine Kinase and Damage DNA with a Green Fluorescent Species

Todorova, M. I., Larroque, A. L., Dauphin-Pierre, S., Fang, Y. Q., Jean-Claude, B. J.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 871 KB

english, 2010

19

RelB-Dependent Differential Radiosensitization Effect of STI571 on Prostate Cancer Cells

Xu, Y., Fang, F., Sun, Y., St. Clair, D. K., St. Clair, W. H.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 909 KB

english, 2010

20

Potent Preclinical Impact of Metronomic Low-Dose Oral Topotecan Combined with the Antiangiogenic Drug Pazopanib for the Treatment of Ovarian Cancer

Hashimoto, K., Man, S., Xu, P., Cruz-Munoz, W., Tang, T., Kumar, R., Kerbel, R. S.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

21

Organic Cation Transporters Modulate the Uptake and Cytotoxicity of Picoplatin, a Third-Generation Platinum Analogue

More, S. S., Li, S., Yee, S. W., Chen, L., Xu, Z., Jablons, D. M., Giacomini, K. M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 621 KB

english, 2010

22

Inhibition of Aldose Reductase Prevents Growth Factor-Induced G1-S Phase Transition through the AKT/Phosphoinositide 3-Kinase/E2F-1 Pathway in Human Colon Cancer Cells

Ramana, K. V., Tammali, R., Srivastava, S. K.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 776 KB

english, 2010

23

Interstitial Infusion of Glioma-Targeted Recombinant Immunotoxin 8H9scFv-PE38

Luther, N., Cheung, N. K., Souliopoulos, E. P., Karempelas, I., Bassiri, D., Edgar, M. A., Guo, H. f., Pastan, I., Gutin, P. H., Souweidane, M. M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

24

AT7519, a Cyclin-Dependent Kinase Inhibitor, Exerts Its Effects by Transcriptional Inhibition in Leukemia Cell Lines and Patient Samples

Squires, M. S., Cooke, L., Lock, V., Qi, W., Lewis, E. J., Thompson, N. T., Lyons, J. F., Mahadevan, D.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 544 KB

english, 2010

25

PF-03814735, an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy

Jani, J. P., Arcari, J., Bernardo, V., Bhattacharya, S. K., Briere, D., Cohen, B. D., Coleman, K., Christensen, J. G., Emerson, E. O., Jakowski, A., Hook, K., Los, G., Moyer, J. D., Pruimboom-Brees, I

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

26

ZD6474, a Multitargeted Inhibitor for Receptor Tyrosine Kinases, Suppresses Growth of Gliomas Expressing an Epidermal Growth Factor Receptor Mutant, EGFRvIII, in the Brain

Yiin, J. J., Hu, B., Schornack, P. A., Sengar, R. S., Liu, K. w., Feng, H., Lieberman, F. S., Chiou, S. H., Sarkaria, J. N., Wiener, E. C., Ma, H. I., Cheng, S. Y.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

27

Antitumor Efficacy Profile of PKI-402, a Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor

Mallon, R., Hollander, I., Feldberg, L., Lucas, J., Soloveva, V., Venkatesan, A., Dehnhardt, C., Delos Santos, E., Chen, Z., dos Santos, O., Ayral-Kaloustian, S., Gibbons, J.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

28

Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer

Merritt, W. M., Nick, A. M., Carroll, A. R., Lu, C., Matsuo, K., Dumble, M., Jennings, N., Zhang, S., Lin, Y. G., Spannuth, W. A., Kamat, A. A., Stone, R. L., Shahzad, M. M. K., Coleman, R. L., Kumar,

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 723 KB

english, 2010

29

Nutlin-3a Induces Cytoskeletal Rearrangement and Inhibits the Migration and Invasion Capacity of p53 Wild-Type Cancer Cells

Moran, D. M., Maki, C. G.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 710 KB

english, 2010

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