Volume 9; Issue 8

Molecular Cancer Therapeutics

Volume 9; Issue 8

1

Decreased Survival of Human Breast Cancer Cells Expressing HER2/neu on In vitro Incubation with an Anti-HER2/neu Antibody Fused to C5a or C5adesArg

Fuenmayor, J., Perez-Vazquez, K., Perez-Witzke, D., Penichet, M. L., Montano, R. F.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 367 KB

english, 2010

2

Systemic Administration of Polymeric Nanoparticle-Encapsulated Curcumin (NanoCurc) Blocks Tumor Growth and Metastases in Preclinical Models of Pancreatic Cancer

Bisht, S., Mizuma, M., Feldmann, G., Ottenhof, N. A., Hong, S.-M., Pramanik, D., Chenna, V., Karikari, C., Sharma, R., Goggins, M. G., Rudek, M. A., Ravi, R., Maitra, A., Maitra, A.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 420 KB

english, 2010

3

Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor

Parry, D., Guzi, T., Shanahan, F., Davis, N., Prabhavalkar, D., Wiswell, D., Seghezzi, W., Paruch, K., Dwyer, M. P., Doll, R., Nomeir, A., Windsor, W., Fischmann, T., Wang, Y., Oft, M., Chen, T., Kirs

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 477 KB

english, 2010

4

Epidermal Growth Factor Receptor-Targeted Radioimmunotherapy of Human Head and Neck Cancer Xenografts Using 90Y-Labeled Fully Human Antibody Panitumumab

Liu, Z., Liu, Y., Jia, B., Zhao, H., Jin, X., Li, F., Chen, X., Wang, F.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 674 KB

english, 2010

5

Ranpirnase (Frog RNase) Targeted with a Humanized, Internalizing, Anti-Trop-2 Antibody Has Potent Cytotoxicity against Diverse Epithelial Cancer Cells

Chang, C.-H., Gupta, P., Michel, R., Loo, M., Wang, Y., Cardillo, T. M., Goldenberg, D. M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 608 KB

english, 2010

6

Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice

Schaffer, B. S., Grayson, M. H., Wortham, J. M., Kubicek, C. B., McCleish, A. T., Prajapati, S. I., Nelon, L. D., Brady, M. M., Jung, I., Hosoyama, T., Sarro, L. M., Hanes, M. A., Rubin, B. P., Michal

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 621 KB

english, 2010

7

Heat Shock Protein 90 Inhibition Depletes TrkA Levels and Signaling in Human Acute Leukemia Cells

Rao, R., Nalluri, S., Fiskus, W., Balusu, R., Joshi, A., Mudunuru, U., Buckley, K. M., Robbins, K., Ustun, C., Reuther, G. W., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

8

Systematic Interpretation of Comutated Genes in Large-Scale Cancer Mutation Profiles

Gu, Y., Yang, D., Zou, J., Ma, W., Wu, R., Zhao, W., Zhang, Y., Xiao, H., Gong, X., Zhang, M., Zhu, J., Guo, Z.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

9

Vascular Endothelial Growth Factor Is a Promising Therapeutic Target for the Treatment of Clear Cell Carcinoma of the Ovary

Mabuchi, S., Kawase, C., Altomare, D. A., Morishige, K., Hayashi, M., Sawada, K., Ito, K., Terai, Y., Nishio, Y., Klein-Szanto, A. J., Burger, R. A., Ohmichi, M., Testa, J. R., Kimura, T.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 929 KB

english, 2010

10

Serine Proteases in Histone Deacetylase Inhibitor-Induced Apoptosis Still an Unresolved Question - Response

Menendez-Gutierrez, M. P., Ferragut, J. A., del Pilar Garcia-Morales, M., Saceda, M., Martinez-Lacaci, I.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 146 KB

english, 2010

11

Sorafenib Activates CD95 and Promotes Autophagy and Cell Death via Src Family Kinases in Gastrointestinal Tumor Cells

Park, M. A., Reinehr, R., Haussinger, D., Voelkel-Johnson, C., Ogretmen, B., Yacoub, A., Grant, S., Dent, P.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 459 KB

english, 2010

12

Suppression of Neurotensin Receptor Type 1 Expression and Function by Histone Deacetylase Inhibitors in Human Colorectal Cancers

Wang, X., Jackson, L. N., Johnson, S. M., Wang, Q., Evers, B. M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

13

Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis

Nagaraj, N. S., Smith, J. J., Revetta, F., Washington, M. K., Merchant, N. B.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 561 KB

english, 2010

14

A Review of Trabectedin (ET-743): A Unique Mechanism of Action

D'Incalci, M., Galmarini, C. M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 564 KB

english, 2010

15

-Tocotrienol Promotes TRAIL-Induced Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase/p53-Mediated Upregulation of Death Receptors

Kannappan, R., Ravindran, J., Prasad, S., Sung, B., Yadav, V. R., Reuter, S., Chaturvedi, M. M., Aggarwal, B. B.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 686 KB

english, 2010

16

Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma

Spannuth, W. A., Mangala, L. S., Stone, R. L., Carroll, A. R., Nishimura, M., Shahzad, M. M. K., Lee, S.-J., Moreno-Smith, M., Nick, A. M., Liu, R., Jennings, N. B., Lin, Y. G., Merritt, W. M., Colema

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 849 KB

english, 2010

17

Phase II Trial to Evaluate Gemcitabine and Etoposide for Locally Advanced or Metastatic Pancreatic Cancer

Melnik, M. K., Webb, C. P., Richardson, P. J., Luttenton, C. R., Campbell, A. D., Monroe, T. J., O'Rourke, T. J., Yost, K. J., Szczepanek, C. M., Bassett, M. R., Truszkowski, K. J., Stein, P., Van Bro

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

18

Dual Targeting of CDK and Tropomyosin Receptor Kinase Families by the Oral Inhibitor PHA-848125, an Agent with Broad-Spectrum Antitumor Efficacy

Albanese, C., Alzani, R., Amboldi, N., Avanzi, N., Ballinari, D., Brasca, M. G., Festuccia, C., Fiorentini, F., Locatelli, G., Pastori, W., Patton, V., Roletto, F., Colotta, F., Galvani, A., Isacchi,

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 702 KB

english, 2010

19

Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth

Carnahan, J., Beltran, P. J., Babij, C., Le, Q., Rose, M. J., Vonderfecht, S., Kim, J. L., Smith, A. L., Nagapudi, K., Broome, M. A., Fernando, M., Kha, H., Belmontes, B., Radinsky, R., Kendall, R., B

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 644 KB

english, 2010

20

Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance with IFN-Stimulated Gene Expression

Luszczek, W., Cheriyath, V., Mekhail, T. M., Borden, E. C.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

21

Overexpression of GRIM-19 in Cancer Cells Suppresses STAT3-Mediated Signal Transduction and Cancer Growth

Okamoto, T., Inozume, T., Mitsui, H., Kanzaki, M., Harada, K., Shibagaki, N., Shimada, S.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

22

Serine Proteases in Histone Deacetylase Inhibitor-Induced Apoptosis - Letter

Sonnemann, J., Palani, C. D., Beck, L. F., Beck, J. F., Appel, B.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 189 KB

english, 2010

23

miR-192/miR-215 Influence 5-Fluorouracil Resistance through Cell Cycle-Mediated Mechanisms Complementary to Its Post-transcriptional Thymidilate Synthase Regulation

Boni, V., Bitarte, N., Cristobal, I., Zarate, R., Rodriguez, J., Maiello, E., Garcia-Foncillas, J., Bandres, E.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

24

Tyrosine Phosphatase Inhibitor-3 Sensitizes Melanoma and Colon Cancer to Biotherapeutics and Chemotherapeutics

Kundu, S., Fan, K., Cao, M., Lindner, D. J., Tuthill, R., Liu, L., Gerson, S., Borden, E., Yi, T.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 472 KB

english, 2010

25

Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis

Chen, Y., Hao, H., He, S., Cai, L., Li, Y., Hu, S., Ye, D., Hoidal, J., Wu, P., Chen, X.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 922 KB

english, 2010

26

Galectin-3 Promotes Chronic Activation of K-Ras and Differentiation Block in Malignant Thyroid Carcinomas

Levy, R., Grafi-Cohen, M., Kraiem, Z., Kloog, Y.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 638 KB

english, 2010

27

Cisplatin Treatment Induces a Transient Increase in Tumorigenic Potential Associated with High Interleukin-6 Expression in Head and Neck Squamous Cell Carcinoma

Poth, K. J., Guminski, A. D., Thomas, G. P., Leo, P. J., Jabbar, I. A., Saunders, N. A.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

28

Expression of ABCG2 (BCRP) Is Regulated by Nrf2 in Cancer Cells That Confers Side Population and Chemoresistance Phenotype

Singh, A., Wu, H., Zhang, P., Happel, C., Ma, J., Biswal, S.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 701 KB

english, 2010

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