Volume 46; Issue 5

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Molecular Cell
Volume 46; Issue 5

Molecular Cell

Volume 46; Issue 5

1

Human Embryonic Stem Cells Have Constitutively Active Bax at the Golgi and Are Primed to Undergo Rapid Apoptosis

Raluca Dumitru, Vivian Gama, B. Matthew Fagan, Jacquelyn J. Bower, Vijay Swahari, Larysa H. Pevny, Mohanish Deshmukh

Journal:

Year:

2012

Language:

english

File:

PDF, 641 KB

english, 2012

2

Stemming Danger with Golgified BAX

Loren D. Walensky

Journal:

Year:

2012

Language:

english

File:

PDF, 348 KB

english, 2012

3

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

Edze R. Westra, Paul B.G. van Erp, Tim Künne, Shi Pey Wong, Raymond H.J. Staals, Christel L.C. Seegers, Sander Bollen, Matthijs M. Jore, Ekaterina Semenova, Konstantin Severinov, Willem M. de Vos, Rem

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Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

4

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

Dipali G. Sashital, Blake Wiedenheft, Jennifer A. Doudna

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Year:

2012

Language:

english

File:

PDF, 3.50 MB

english, 2012

5

TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex

Gobi Thillainadesan, Jennifer Mary Chitilian, Majdina Isovic, Jailal Nicholas George Ablack, Joe Stephen Mymryk, Marc Tini, Joseph Torchia

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Year:

2012

Language:

english

File:

PDF, 1.62 MB

english, 2012

6

Mechanism of Homology Recognition in DNA Recombination from Dual-Molecule Experiments

Iwijn De Vlaminck, Marijn T.J. van Loenhout, Ludovit Zweifel, Johan den Blanken, Koen Hooning, Susanne Hage, Jacob Kerssemakers, Cees Dekker

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Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

7

RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation

Long Zhang, Huizhe Huang, FangFang Zhou, Joost Schimmel, Cristina Gontan Pardo, Tingting Zhang, Tahsin Stefan Barakat, Kelly-Ann Sheppard, Craig Mickanin, Jeff A. Porter, Alfred C.O. Vertegaal, Hans v

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Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

8

Antibiotic-Induced Bacterial Cell Death Exhibits Physiological and Biochemical Hallmarks of Apoptosis

Daniel J. Dwyer, Diogo M. Camacho, Michael A. Kohanski, Jarred M. Callura, James J. Collins

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Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

9

Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response

Richard C. Centore, Stephanie A. Yazinski, Alice Tse, Lee Zou

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Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

10

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

Alexander G. Baltz, Mathias Munschauer, Björn Schwanhäusser, Alexandra Vasile, Yasuhiro Murakawa, Markus Schueler, Noah Youngs, Duncan Penfold-Brown, Kevin Drew, Miha Milek, Emanuel Wyler, Richard Bon

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Year:

2012

Language:

english

File:

PDF, 2.10 MB

english, 2012

11

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

Oleksandra Karpiuk, Zeynab Najafova, Frank Kramer, Magali Hennion, Christina Galonska, Annekatrin König, Nicolas Snaidero, Tanja Vogel, Andrei Shchebet, Yvonne Begus-Nahrmann, Moustapha Kassem, Mikael

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Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

12

RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

Gilad Fuchs, Efrat Shema, Rita Vesterman, Eran Kotler, Zohar Wolchinsky, Sylvia Wilder, Lior Golomb, Ariel Pribluda, Feng Zhang, Mahmood Haj-Yahya, Ester Feldmesser, Ashraf Brik, Xiaochun Yu, Jacob Ha

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Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

13

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

Colm J. Ryan, Assen Roguev, Kristin Patrick, Jiewei Xu, Harlizawati Jahari, Zongtian Tong, Pedro Beltrao, Michael Shales, Hong Qu, Sean R. Collins, Joseph I. Kliegman, Lingli Jiang, Dwight Kuo, Elena

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Year:

2012

Language:

english

File:

PDF, 1.95 MB

english, 2012

14

Feedback Control of Adrenal Steroidogenesis via H2O2-Dependent, Reversible Inactivation of Peroxiredoxin III in Mitochondria

In Sup Kil, Se Kyoung Lee, Keun Woo Ryu, Hyun Ae Woo, Meng-Chun Hu, Soo Han Bae, Sue Goo Rhee

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Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

15

TGF-β Drives DNA Demethylation

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Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

16

When Death Was Young: An Ancestral Apoptotic Network in Bacteria

Didac Carmona-Gutierrez, Guido Kroemer, Frank Madeo

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Year:

2012

Language:

english

File:

PDF, 154 KB

english, 2012

17

Inhibiting the Inhibitor: The Role of RNF12 in TGF-β Superfamily Signaling

Caroline S. Hill

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Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

18

How to Regulate a Gene: To Repress or to Activate?

Nikolai Slavov, Alexander van Oudenaarden

Journal:

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012