Volume 2; Issue 1

Molecular Neurodegeneration

Volume 2; Issue 1

1

Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

Tom N Grammatopoulos, Susan M Jones, Ferogh A Ahmadi, Brian R Hoover, Lawrence D Snell, Jesse Skoch, Vimal V Jhaveri, Andy M Poczobutt, James A Weyhenmeyer, W Michael Zawada

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 2.48 MB

english, 2007

2

Absence of dopaminergic neuronal degeneration and oxidative damage in agedDJ-1-deficient mice

Hiroo Yamaguchi, Jie Shen

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.79 MB

english, 2007

3

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels

Patricia A Lawlor, Ross J Bland, Pritam Das, Robert W Price, Vallie Holloway, Lisa Smithson, Bridget L Dicker, Matthew J During, Deborah Young, Todd E Golde

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.79 MB

english, 2007

4

Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

Carolyn A Rankin, Qian Sun, Truman C Gamblin

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 3.16 MB

english, 2007

5

From a Parkinson's disease expert: Rasagiline and the Future of Therapy

Shaheen E Lakhan

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 356 KB

english, 2007

6

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity

Rodrigo A Fuentealba, Maria Ines Barría, Jiyeon Lee, Judy Cam, Claudia Araya, Claudia A Escudero, Nibaldo C Inestrosa, Francisca C Bronfman, Guojun Bu, Maria-Paz Marzolo

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.66 MB

english, 2007

7

An AICD-based functional screen to identify APP metabolism regulators

Can Zhang, Preeti J Khandelwal, Ranjita Chakraborty, Trinna L Cuellar, Srikant Sarangi, Shyam A Patel, Christopher P Cosentino, Michael O'Connor, Jeremy C Lee, Rudolph E Tanzi, Aleister J Saunders

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.84 MB

english, 2007

8

Design of an improved set of oligonucleotide primers for genotyping MeCP2tm1.1BirdKO mice by PCR

Julie Miralvès, Eddy Magdeleine, Etienne Joly

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 331 KB

english, 2007

9

Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau

Ismael Santa-Maria, Félix Hernández, Joaquín Del Rio, Francisco J Moreno, Jesús Avila

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.49 MB

english, 2007

10

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L Thompson, Suhail Rasool, Tatyana Gurlo, Peter Butler, Cha

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.45 MB

english, 2007

11

Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease

Wei-Guo Liu, Xi-Jing Wang, Guo-Qiang Lu, Biao Li, Gang Wang, Sheng-Di Chen

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 753 KB

english, 2007

12

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

Gemma Casadesus, Mark A Smith, Samar Basu, Jing Hua, Dae E Capobianco, Sandra L Siedlak, Xiongwei Zhu, George Perry

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

13

Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment

Iliya Lefterov, Angie Bookout, Zhu Wang, Matthias Staufenbiel, David Mangelsdorf, Radosveta Koldamova

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.58 MB

english, 2007

14

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene

Thomas M Wishart, Stephen HF MacDonald, Philip E Chen, Michael J Shipston, Michael P Coleman, Thomas H Gillingwater, Richard R Ribchester

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

15

The Alzheimer's disease β-secretase enzyme, BACE1

Sarah L Cole, Robert Vassar

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

16

Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding

Annat F Ikin, Mirsada Causevic, Steve Pedrini, Lyndsey S Benson, Joseph D Buxbaum, Toshiharu Suzuki, Simon Lovestone, Shigeki Higashiyama, Tomas Mustelin, Robert D Burgoyne, Sam Gandy

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

17

APP-BP1 inhibits Aβ42 levels by interacting with Presenilin-1

Yuzhi Chen, Angela M Bodles, Donna L McPhie, Rachael L Neve, Robert E Mrak, W Sue T Griffin

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

18

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

Kulandaivelu S Vetrivel, Ping Gong, James W Bowen, Haipeng Cheng, Ying Chen, Meghan Carter, Phuong D Nguyen, Lisa Placanica, Felix T Wieland, Yue-Ming Li, Maria Z Kounnas, Gopal Thinakaran

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 1.70 MB

english, 2007

19

Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease

Michael J Stobart, Debra Parchaliuk, Sharon LR Simon, Jillian LeMaistre, Jozef Lazar, Richard Rubenstein, J David Knox

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 895 KB

english, 2007

20

Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

Verena Kallhoff, Erica Peethumnongsin, Hui Zheng

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 727 KB

english, 2007

21

Apolipoprotein E levels in cerebrospinal fluid and the effects ofABCA1polymorphisms

Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate, David M Holtzman

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

22

Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

Xiaofeng Gu, Véronique M André, Carlos Cepeda, Shi-Hua Li, Xiao-Jiang Li, Michael S Levine, X William Yang

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 2.30 MB

english, 2007

23

Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

Jian-Sheng Gong, Shin-ya Morita, Mariko Kobayashi, Tetsurou Handa, Shinobu C Fujita, Katsuhiko Yanagisawa, Makoto Michikawa

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 468 KB

english, 2007