Volume 11; Issue 10

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Molecular Pharmaceutics
Volume 11; Issue 10

Molecular Pharmaceutics

Volume 11; Issue 10

1

Simultaneous Inhibition of Tumor Growth and Angiogenesis for Resistant Hepatocellular Carcinoma by Co-delivery of Sorafenib and Survivin Small Hairpin RNA

Shen, Jianan, Sun, Huiping, Meng, Qingshuo, Yin, Qi, Zhang, Zhiwen, Yu, Haijun, Li, Yaping

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

2

Hepatic-Targeted Gene Delivery Using Cationic Mannan Vehicle

Ruan, Gui-Xin, Zhang, Tian-Yuan, Li, Li-Ming, Zhang, Xing-Guo, Shen, You-Qing, Tabata, Yasuhiko, Gao, Jian-Qing

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 24.60 MB

english, 2014

3

A Tumor Environment Responsive Doxorubicin-Loaded Nanoparticle for Targeted Cancer Therapy

Zhu, Qian, Jia, Lixin, Gao, Zhongfei, Wang, Chunming, Jiang, Haoyang, Zhang, Junfeng, Dong, Lei

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.71 MB

english, 2014

4

Thymopentin Nanoparticles Engineered with High Loading Efficiency, Improved Pharmacokinetic Properties, and Enhanced Immunostimulating Effect Using Soybean Phospholipid and PHBHHx Polymer

Wu, Chengyu, Zhang, Mengtian, Zhang, Zhirong, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David A., Elhissi, Abdelbary M. A., Sun, Xun

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

5

A Novel Doxorubicin-Loaded in Situ Forming Gel Based High Concentration of Phospholipid for Intratumoral Drug Delivery

Wu, Wenqi, Chen, Hui, Shan, Fengying, Zhou, Jing, Sun, Xun, Zhang, Ling, Gong, Tao

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 5.80 MB

english, 2014

6

Multifunctional Metal Rattle-Type Nanocarriers for MRI-Guided Photothermal Cancer Therapy

Huang, Yuran, Wei, Tuo, Yu, Jing, Hou, Yanglong, Cai, Kaiyong, Liang, Xing-Jie

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.69 MB

english, 2014

7

Inhibition of Metastatic Tumor Growth and Metastasis via Targeting Metastatic Breast Cancer by Chlorotoxin-Modified Liposomes

Qin, Chao, He, Bing, Dai, Wenbing, Zhang, Hua, Wang, Xueqing, Wang, Jiancheng, Zhang, Xuan, Wang, Guangji, Yin, Lifang, Zhang, Qiang

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.89 MB

english, 2014

8

Gastroretentive Extended-Release Floating Granules Prepared Using a Novel Fluidized Hot Melt Granulation (FHMG) Technique

Zhai, H., Jones, D. S., McCoy, C. P., Madi, A. M., Tian, Y., Andrews, G. P.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 7.82 MB

english, 2014

9

Mad2 Checkpoint Gene Silencing Using Epidermal Growth Factor Receptor-Targeted Chitosan Nanoparticles in Non-Small Cell Lung Cancer Model

Nascimento, Ana Vanessa, Singh, Amit, Bousbaa, Hassan, Ferreira, Domingos, Sarmento, Bruno, Amiji, Mansoor M.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.57 MB

english, 2014

10

Transport Pathways of Solid Lipid Nanoparticles Across Madin–Darby Canine Kidney Epithelial Cell Monolayer

Chai, Gui-Hong, Hu, Fu-Qiang, Sun, Jihong, Du, Yong-Zhong, You, Jian, Yuan, Hong

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

11

Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer

Wang, Huiyuan, Wang, Huixin, Liang, Jianming, Jiang, Yifan, Guo, Qianqian, Peng, Huige, Xu, Qin, Huang, Yongzhuo

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 5.07 MB

english, 2014

12

Pharmaceutical Cocrystals of Diflunisal and Diclofenac with Theophylline

Surov, Artem O., Voronin, Alexander P., Manin, Alex N., Manin, Nikolay G., Kuzmina, Lyudmila G., Churakov, Andrei V., Perlovich, German L.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

13

Beyond the Great Wall: Recent Advances in Molecular Pharmaceutics Research in China

Huang, Yuan, Sun, Xun

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 129 KB

english, 2014

14

A Bacteria Deriving Peptide Modified Dendrigraft Poly- l -lysines (DGL) Self-Assembling Nanoplatform for Targeted Gene Delivery

Liu, Yang, He, Xi, Kuang, Yuyang, An, Sai, Wang, Chenyu, Guo, Yubo, Ma, Haojun, Lou, Jinning, Jiang, Chen

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

15

Peptides Used in the Delivery of Small Noncoding RNA

Shukla, Ravi S., Qin, Bin, Cheng, Kun

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.13 MB

english, 2014

16

Prodrugs of Pioglitazone for Extended-Release (XR) Injectable Formulations

Sanrame, Carlos N., Remenar, Julius F., Blumberg, Laura C., Waters, Julie, Dean, Reginald L., Dong, Nan, Kriksciukaite, Kristi, Cao, Peixin, Almarsson, Örn

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 983 KB

english, 2014

17

Retro-Inverso Isomer of Angiopep-2: A Stable d -Peptide Ligand Inspires Brain-Targeted Drug Delivery

Wei, Xiaoli, Zhan, Changyou, Chen, Xishan, Hou, Jiapeng, Xie, Cao, Lu, Weiyue

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 6.15 MB

english, 2014

18

Polyspermine imine, a pH Responsive Polycationic siRNA Carrier Degradable to Endogenous Metabolites

Du, Zixiu, Xiang, Shengnan, Zang, Yi, Zhou, Yi, Wang, Chuandong, Tang, Hailing, Jin, Tuo, Zhang, Xiaoling

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.38 MB

english, 2014

19

Impact of Polymers on the Crystallization and Phase Transition Kinetics of Amorphous Nifedipine during Dissolution in Aqueous Media

Raina, Shweta A., Alonzo, David E., Zhang, Geoff G. Z., Gao, Yi, Taylor, Lynne S.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.21 MB

english, 2014

20

Involvement of Carrier-Mediated Transport in the Retinal Uptake of Clonidine at the Inner Blood–Retinal Barrier

Kubo, Yoshiyuki, Tsuchiyama, Ai, Shimizu, Yoshimi, Akanuma, Shin-ichi, Hosoya, Ken-ichi

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 498 KB

english, 2014

21

[ 18 F]DPA-714 PET Imaging of AMD3100 Treatment in a Mouse Model of Stroke

Wang, Yu, Yue, Xuyi, Kiesewetter, Dale O., Wang, Zhe, Lu, Jie, Niu, Gang, Teng, Gaojun, Chen, Xiaoyuan

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.19 MB

english, 2014

22

Evaluation of Biocompatibility of the AC8 Peptide and Its Potential Use as a Drug Carrier

Naahidi, Sheva, Wang, Yujie, Zhang, Man, Wang, Rong, Jafari, Mousa, Yuan, Yongfang, Dixon, Brian, Chen, P.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.65 MB

english, 2014

23

Development of Nanodroplets for Histotripsy-Mediated Cell Ablation

Yuksel Durmaz, Yasemin, Vlaisavljevich, Eli, Xu, Zhen, ElSayed, Mohamed

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 6.67 MB

english, 2014

24

Protein Abundance of Clinically Relevant Multidrug Transporters along the Entire Length of the Human Intestine

Drozdzik, Marek, Gröer, Christian, Penski, Jette, Lapczuk, Joanna, Ostrowski, Marek, Lai, Yurong, Prasad, Bhagwat, Unadkat, Jashvant D., Siegmund, Werner, Oswald, Stefan

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 972 KB

english, 2014

25

Antibacterial Activities of Amphiphilic Cyclic Cell-Penetrating Peptides against Multidrug-Resistant Pathogens

Oh, Donghoon, Sun, Jiadong, Nasrolahi Shirazi, Amir, LaPlante, Kerry L., Rowley, David C., Parang, Keykavous

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.20 MB

english, 2014

26

Adjuvant Cationic Liposomes Presenting MPL and IL-12 Induce Cell Death, Suppress Tumor Growth, and Alter the Cellular Phenotype of Tumors in a Murine Model of Breast Cancer

Meraz, Ismail M., Savage, David J., Segura-Ibarra, Victor, Li, Jeffrey, Rhudy, Jessica, Gu, Jianhua, Serda, Rita E.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.08 MB

english, 2014

27

Effect of Surface Functionality of Silica Nanoparticles on Cellular Uptake and Cytotoxicity

Jambhrunkar, Siddharth, Qu, Zhi, Popat, Amirali, Yang, Jie, Noonan, Owen, Acauan, Luiz, Ahmad Nor, Yusilawati, Yu, Chengzhong, Karmakar, Surajit

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.15 MB

english, 2014

28

Generation and Screening of Monoclonal Antibodies for ImmunoPET Imaging of IGF1R in Prostate Cancer

Hong, Hao, Nayak, Tapas R., Shi, Sixiang, Graves, Stephen A., Fliss, Brianne C., Barnhart, Todd E., Cai, Weibo

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.91 MB

english, 2014

29

Effects of Surface Displayed Targeting Ligand GE11 on Liposome Distribution and Extravasation in Tumor

Tang, Hailing, Chen, Xiaojing, Rui, Mengjie, Sun, Wenqiang, Chen, Jian, Peng, Jinliang, Xu, Yuhong

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

30

Role of the Phospholipase A 2 Receptor in Liposome Drug Delivery in Prostate Cancer Cells

Quach, N. D., Mock, J. N., Scholpa, N. E., Eggert, M. W., Payré, C., Lambeau, G., Arnold, R. D., Cummings, B. S.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.58 MB

english, 2014

31

One Stone Kills Three Birds: Novel Boron-Containing Vesicles for Potential BNCT, Controlled Drug Release, and Diagnostic Imaging

Chen, Gaojian, Yang, Jingying, Lu, Gang, Liu, Pi Chu, Chen, Qianjin, Xie, Zuowei, Wu, Chi

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.53 MB

english, 2014

32

Designing Hybrid Onconase Nanocarriers for Mesothelioma Therapy: A Taguchi Orthogonal Array and Multivariate Component Driven Analysis

Tekade, Rakesh K., Youngren-Ortiz, Susanne R., Yang, Haining, Haware, Rahul, Chougule, Mahavir B.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.20 MB

english, 2014

33

Beyond Overton’s Rule: Quantitative Modeling of Passive Permeation through Tight Cell Monolayers

Filipe, H. A. L., Salvador, A., Silvestre, J. M., Vaz, W. L. C., Moreno, M. J.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

34

PEG-Stabilized Bilayer Nanodisks As Carriers for Doxorubicin Delivery

Zhang, Wenping, Sun, Jin, Liu, Yan, Tao, Mengying, Ai, Xiaoyu, Su, Xiaonan, Cai, Cuifang, Tang, Yilin, Feng, Zhi, Yan, Xiaodan, Chen, Guoliang, He, Zhonggui

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.15 MB

english, 2014

35

Folate Receptor-β in Activated Macrophages: Ligand Binding and Receptor Recycling Kinetics

Varghese, Bindu, Vlashi, Erina, Xia, Wei, Ayala Lopez, Wilfredo, Paulos, Chrystal M., Reddy, Joseph, Xu, Le-Cun, Low, Philip S.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

36

Structure-Based Prediction of Drug Distribution Across the Headgroup and Core Strata of a Phospholipid Bilayer Using Surrogate Phases

Natesan, Senthil, Lukacova, Viera, Peng, Ming, Subramaniam, Rajesh, Lynch, Sandra, Wang, Zhanbin, Tandlich, Roman, Balaz, Stefan

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.97 MB

english, 2014

37

Understanding API–Polymer Proximities in Amorphous Stabilized Composite Drug Products Using Fluorine–Carbon 2D HETCOR Solid-State NMR

Abraham, Anuji, Crull, George

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

38

Shape-Controlled Paclitaxel Nanoparticles with Multiple Morphologies: Rod-Shaped, Worm-Like, Spherical, and Fingerprint-Like

Wang, Yongjun, Wang, Dun, Fu, Qiang, Liu, Dan, Ma, Yan, Racette, Kelly, He, Zhonggui, Liu, Feng

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.31 MB

english, 2014

39

Bacterial Cellulose/Acrylamide pH-Sensitive Smart Hydrogel: Development, Characterization, and Toxicity Studies in ICR Mice Model

Pandey, Manisha, Mohamad, Najwa, Amin, Mohd Cairul Iqbal Mohd

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.61 MB

english, 2014

40

Successful Entrapping of Liposomes in Glucan Particles: An Innovative Micron-Sized Carrier to Deliver Water-Soluble Molecules

Garello, Francesca, Stefania, Rachele, Aime, Silvio, Terreno, Enzo, Delli Castelli, Daniela

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.10 MB

english, 2014

41

Relationship between Native-State Solubility and Non-Native Aggregation of Recombinant Human Granulocyte Colony Stimulating Factor: Practical Implications for Protein Therapeutic Development

Banks, Douglas D., Zhang, Jun, Siska, Christine C.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.60 MB

english, 2014

42

Comparison of Binding Characteristics and In Vitro Activities of Three Inhibitors of Vascular Endothelial Growth Factor A

Yang, Jihong, Wang, Xiangdan, Fuh, Germaine, Yu, Lanlan, Wakshull, Eric, Khosraviani, Mehraban, Day, Eric S., Demeule, Barthélemy, Liu, Jun, Shire, Steven J., Ferrara, Napoleone, Yadav, Sandeep

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

43

Cyclic Peptide–Selenium Nanoparticles as Drug Transporters

Nasrolahi Shirazi, Amir, Tiwari, Rakesh K., Oh, Donghoon, Sullivan, Brian, Kumar, Anil, Beni, Yousef A., Parang, Keykavous

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 4.21 MB

english, 2014

44

Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette Transporter ABCB5

Keniya, Mikhail V., Holmes, Ann R., Niimi, Masakazu, Lamping, Erwin, Gillet, Jean-Pierre, Gottesman, Michael M., Cannon, Richard D.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.36 MB

english, 2014

45

Versatile Reticular Polyethylenimine Derivative-Mediated Targeted Drug and Gene Codelivery for Tumor Therapy

Ding, Xuefang, Wang, Wei, Wang, Yazhe, Bao, Xiuli, Wang, Yu, Wang, Cheng, Chen, Jian, Zhang, Fangrong, Zhou, Jianping

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.15 MB

english, 2014

46

Novel Free-Paclitaxel-Loaded Redox-Responsive Nanoparticles Based on a Disulfide-Linked Poly(ethylene glycol)–Drug Conjugate for Intracellular Drug Delivery: Synthesis, Characterization, and Antitumor Activity in Vitro and in Vivo

Chuan, Xingxing, Song, Qin, Lin, Jialiang, Chen, Xianhui, Zhang, Hua, Dai, Wenbing, He, Bing, Wang, Xueqing, Zhang, Qiang

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 8.06 MB

english, 2014

47

Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

Hu, Yongjun, Xie, Yehua, Wang, Yuqing, Chen, Xiaomei, Smith, David E.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

48

Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N -(2-Hydroxypropyl)methacrylamide Copolymers

Yang, Yang, Li, Lian, Zhou, Zhou, Yang, Qingqing, Liu, Chong, Huang, Yuan

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 5.03 MB

english, 2014

49

Poly(ethylene glycol)-Mediated Conformational Alteration of α-Chymotrypsin Prevents Inactivation of Insulin by Stabilizing Active Intermediates

Yu, Jibing, Wei, Xiuli, Zhang, Li, Fang, Xiaocui, Yang, Tao, Huang, Feng, Liang, Wei

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 2.99 MB

english, 2014

50

Effect of Conformation on the Photodegradation of Trp- And Cystine-Containing Cyclic Peptides: Octreotide and Somatostatin

Mozziconacci, Olivier, Schöneich, Christian

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

51

Rational Design of Artificial β-Strand-Forming Antimicrobial Peptides with Biocompatible Properties

Rapsch, Karsten, Bier, Frank F., von Nickisch-Rosenegk, Markus

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

52

Overexpression of Human ABCB1 in Cancer Cells Leads to Reduced Activity of GSK461364, a Specific Inhibitor of Polo-like Kinase 1

Wu, Chung-Pu, Hsiao, Sung-Han, Luo, Shi-Yu, Tuo, Wei-Cherng, Su, Ching-Ya, Li, Yan-Qing, Huang, Yang-Hui, Hsieh, Chia-Hung

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 5.15 MB

english, 2014

53

Mechanistic Studies of a Novel Mycophenolic Acid–Glucosamine Conjugate That Attenuates Renal Ischemia/Reperfusion Injury in Rat

Wang, Xiaohong, Xiong, Menghua, Zeng, Yingchun, Sun, Xun, Gong, Tao, Zhang, Zhirong

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.21 MB

english, 2014

54

On the Barrier Properties of the Cornea: A Microscopy Study of the Penetration of Fluorescently Labeled Nanoparticles, Polymers, and Sodium Fluorescein

Mun, Ellina A., Morrison, Peter W. J., Williams, Adrian C., Khutoryanskiy, Vitaliy V.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 3.34 MB

english, 2014

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