Volume 20; Issue 5

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Molecular Therapy
Volume 20; Issue 5

Molecular Therapy

Volume 20; Issue 5

1

Extensive Methylation of Promoter Sequences Silences Lentiviral Transgene Expression During Stem Cell Differentiation In Vivo

Herbst, Friederike, Ball, Claudia R, Tuorto, Francesca, Nowrouzi, Ali, Wang, Wei, Zavidij, Oksana, Dieter, Sebastian M, Fessler, Sylvia, van der Hoeven, Franciscus, Kloz, Ulrich

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 400 KB

english, 2012

2

Regulation of Stem Cell Plasticity: Mechanisms and Relevance to Tissue Biology and Cancer

Hamerlik, Petra, Lieber, André, Bartek, Jiri, Strauss, Robert

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 247 KB

english, 2012

3

Radiation-inducible Immunotherapy for Cancer: Senescent Tumor Cells as a Cancer Vaccine

Meng, Yuru, Efimova, Elena V, Hamzeh, Khaled W, Darga, Thomas E, Mauceri, Helena J., Fu, Yang-Xin, Kron, Stephen J, Weichselbaum, Ralph R

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 3.21 MB

english, 2012

4

Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4+ and CD8+ T Cells in Melanoma Patients

Van Nuffel, An MT, Benteyn, Daphné, Wilgenhof, Sofie, Pierret, Lauranne, Corthals, Jurgen, Heirman, Carlo, van der Bruggen, Pierre, Coulie, Pierre G, Neyns, Bart, Thielemans, Kris

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1.70 MB

english, 2012

5

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Maguire, Casey A, Balaj, Leonora, Sivaraman, Sarada, Crommentuijn, Matheus HW, Ericsson, Maria, Mincheva-Nilsson, Lucia, Baranov, Vladimir, Gianni, Davide, Tannous, Bakhos A, Sena-Esteves, Miguel, Bre

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

6

Reversal of Diabetes Through Gene Therapy of Diabetic Rats by Hepatic Insulin Expression via Lentiviral Transduction

Elsner, Matthias, Terbish, Taivankhuu, Jörns, Anne, Naujok, Ortwin, Wedekind, Dirk, Hedrich, Hans-Jürgen, Lenzen, Sigurd

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 434 KB

english, 2012

7

Transient Focal Membrane Deformation Induced by Arginine-rich Peptides Leads to Their Direct Penetration into Cells

Hirose, Hisaaki, Takeuchi, Toshihide, Osakada, Hiroko, Pujals, Sílvia, Katayama, Sayaka, Nakase, Ikuhiko, Kobayashi, Shouhei, Haraguchi, Tokuko, Futaki, Shiroh

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

8

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

Suerth, Julia D, Maetzig, Tobias, Brugman, Martijn H, Heinz, Niels, Appelt, Jens-Uwe, Kaufmann, Kerstin B, Schmidt, Manfred, Grez, Manuel, Modlich, Ute, Baum, Christopher, Schambach, Axel

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 243 KB

english, 2012

9

Cancer Immunotherapy Using a Membrane-bound Interleukin-12 With B7-1 Transmembrane and Cytoplasmic Domains

Pan, Wen-Yu, Lo, Chia-Hui, Chen, Chun-Chi, Wu, Ping-Yi, Roffler, Steve R, Shyue, Song-Kun, Tao, Mi-Hua

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

10

Nonmyeloablative Conditioning Regimen to Increase Engraftment of Gene-modified Hematopoietic Stem Cells in Young Rhesus Monkeys

Tarantal, Alice F, Giannoni, Francesca, I Lee, C Chang, Wherley, Jennifer, Sumiyoshi, Teiko, Martinez, Michele, Kahl, Christoph A, Elashoff, David, Louie, Stan G, Kohn, Donald B

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 2.94 MB

english, 2012

11

Soluble Vascular Endothelial Growth Factor Decoy Receptor FP3 Exerts Potent Antiangiogenic Effects

Yu, De-Chao, Lee, Jung-Sun, Yoo, Ji Young, Shin, Hyewon, Deng, Hongxin, Wei, Yuquan, Yun, Chae-Ok

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 501 KB

english, 2012

12

Directing Integrin-linked Endocytosis of Recombinant AAV Enhances Productive FAK-dependent Transduction

Kaminsky, Paul M, Keiser, Nicholas W, Yan, Ziying, Lei-Butters, Diana CM, Engelhardt, John F

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

13

Lens Epithelium-derived Growth Factor/p75 Qualifies as a Target for HIV Gene Therapy in the NSG Mouse Model

Vets, Sofie, Kimpel, Janine, Volk, Andreas, De Rijck, Jan, Schrijvers, Rik, Verbinnen, Bert, Maes, Wim, Von Laer, Dorothee, Debyser, Zeger, Gijsbers, Rik

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 526 KB

english, 2012

14

Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin

Karikó, Katalin, Muramatsu, Hiromi, Keller, Jason M, Weissman, Drew

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 171 KB

english, 2012

15

Cell Fate Control Gene Therapy Based on Engineered Variants of Human Deoxycytidine Kinase

Neschadim, Anton, Wang, James CM, Sato, Takeya, Fowler, Daniel H, Lavie, Arnon, Medin, Jeffrey A

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

16

UU/UA Dinucleotide Frequency Reduction in Coding Regions Results in Increased mRNA Stability and Protein Expression

Al-Saif, Maher, Khabar, Khalid SA

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 378 KB

english, 2012

17

The State of Gene Therapies: The FDA Perspective

Takefman, Daniel, Bryan, Wilson

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 190 KB

english, 2012

18

Neonatal Gene Therapy With a Gamma Retroviral Vector in Mucopolysaccharidosis VI Cats

Ponder, Katherine P, O'Malley, Thomas M, Wang, Ping, O'Donnell, Patricia A, Traas, Anne M, Knox, Van W, Aguirre, Gustavo A, Ellinwood, N Matthew, Metcalf, Jason A, Wang, Bin, Parkinson-Lawrence, Emma

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 710 KB

english, 2012

19

Human Tumor Xenografts: The Good, the Bad, and the Ugly

Morgan, Richard A

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 224 KB

english, 2012

20

Is the Induction of Tumor Cell Senescence the Key to a Good Irradiated Tumor Vaccine?

Brown, Michael P

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 820 KB

english, 2012

21

Replication-competent Herpes Simplex Virus Retargeted to HER2 as Therapy for High-grade Glioma

Gambini, Eleonora, Reisoli, Elisa, Appolloni, Irene, Gatta, Valentina, Campadelli-Fiume, Gabriella, Menotti, Laura, Malatesta, Paolo

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 5.29 MB

english, 2012

22

Corrigendum: Discovery of a Linear Peptide for Improving Tumor Targeting of Gene Products and Treatment of Distal Tumors by IL-12 Gene Therapy

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 346 KB

english, 2012

23

In This Issue

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

24

Corrigendum to “Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses”

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 43 KB

english, 2012

25

Research Highlights

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 529 KB

english, 2012

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