Volume 25; Issue 4

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Molecular Therapy
Volume 25; Issue 4

Molecular Therapy

Volume 25; Issue 4

1

Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer

Huang, Mingde, Hou, Jiakai, Wang, Yunfei, Xie, Min, Wei, Chenchen, Nie, Fengqi, Wang, Zhaoxia, Sun, Ming

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 4.63 MB

english, 2017

2

Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

Watkins, Hannah C., Rappazzo, C. Garrett, Higgins, Jaclyn S., Sun, Xiangjie, Brock, Nicole, Chau, Annie, Misra, Aditya, Cannizzo, Joseph P.B., King, Michael R., Maines, Taronna R., Leifer, Cynthia A.,

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 1.79 MB

english, 2017

3

Systemic Injection of RPE65 -Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration

Qi, Xiaoping, Pay, S. Louise, Yan, Yuanqing, Thomas, James, Lewin, Alfred S., Chang, Lung-Ji, Grant, Maria B., Boulton, Michael E.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.00 MB

english, 2017

4

A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity

Walters, Jewell N., Ferraro, Bernadette, Duperret, Elizabeth K., Kraynyak, Kimberly A., Chu, Jaemi, Saint-Fleur, Ashley, Yan, Jian, Levitsky, Hy, Khan, Amir S., Sardesai, Niranjan Y., Weiner, David B.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.07 MB

english, 2017

5

Systemic AAV8-Mediated Gene Therapy Drives Whole-Body Correction of Myotubular Myopathy in Dogs

Mack, David L., Poulard, Karine, Goddard, Melissa A., Latournerie, Virginie, Snyder, Jessica M., Grange, Robert W., Elverman, Matthew R., Denard, Jérôme, Veron, Philippe, Buscara, Laurine, Le Bec, Chr

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.95 MB

english, 2017

6

Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects

Miura, Naoya, Akita, Hidetaka, Tateshita, Naho, Nakamura, Takashi, Harashima, Hideyoshi

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 891 KB

english, 2017

7

Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease

Carmona, Vitor, Cunha-Santos, Janete, Onofre, Isabel, Simões, Ana Teresa, Vijayakumar, Udaya, Davidson, Beverly L., Pereira de Almeida, Luís

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.85 MB

english, 2017

8

Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy

Shim, Kevin G., Zaidi, Shane, Thompson, Jill, Kottke, Tim, Evgin, Laura, Rajani, Karishma R., Schuelke, Matthew, Driscoll, Christopher B., Huff, Amanda, Pulido, Jose S., Vile, Richard G.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

9

Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells

MacLeod, Daniel T., Antony, Jeyaraj, Martin, Aaron J., Moser, Rachel J., Hekele, Armin, Wetzel, Keith J., Brown, Audrey E., Triggiano, Melissa A., Hux, Jo Ann, Pham, Christina D., Bartsevich, Victor V

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.41 MB

english, 2017

10

Gene Therapeutic Reversal of Peripheral Olfactory Impairment in Bardet-Biedl Syndrome

Williams, Corey L., Uytingco, Cedric R., Green, Warren W., McIntyre, Jeremy C., Ukhanov, Kirill, Zimmerman, Arthur D., Shively, Dana T., Zhang, Lian, Nishimura, Darryl Y., Sheffield, Val C., Martens,

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.81 MB

english, 2017

11

Novel Biomarkers of Human GM1 Gangliosidosis Reflect the Clinical Efficacy of Gene Therapy in a Feline Model

Gray-Edwards, Heather L., Regier, Debra S., Shirley, Jamie L., Randle, Ashley N., Salibi, Nouha, Thomas, Sarah E., Latour, Yvonne L., Johnston, Jean, Golas, Gretchen, Maguire, Annie S., Taylor, Amanda

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.69 MB

english, 2017

12

The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer

Kong, Pengfei, Zhu, Xiaofeng, Geng, Qirong, Xia, Liangping, Sun, Xiaowei, Chen, Yingbo, Li, Wei, Zhou, Zhiwei, Zhan, Youqing, Xu, Dazhi

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

13

The Balance between CD8 + T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose

Kumar, Sandeep R.P., Hoffman, Brad E., Terhorst, Cox, de Jong, Ype P., Herzog, Roland W.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

14

Follistatin Gene Therapy for Sporadic Inclusion Body Myositis Improves Functional Outcomes

Mendell, Jerry R., Sahenk, Zarife, Al-Zaidy, Samiah, Rodino-Klapac, Louise R., Lowes, Linda P., Alfano, Lindsay N., Berry, Katherine, Miller, Natalie, Yalvac, Mehmet, Dvorchik, Igor, Moore-Clingenpeel

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

15

Elderly Patient-Derived Endothelial Cells for Vascularization of Engineered Muscle

Perry, Luba, Flugelman, Moshe Y., Levenberg, Shulamit

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 5.28 MB

english, 2017

16

Systemic AAV-Mediated β-Sarcoglycan Delivery Targeting Cardiac and Skeletal Muscle Ameliorates Histological and Functional Deficits in LGMD2E Mice

Pozsgai, Eric R., Griffin, Danielle A., Heller, Kristin N., Mendell, Jerry R., Rodino-Klapac, Louise R.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 4.06 MB

english, 2017

17

Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons

Weinberg, Marc S., Criswell, Hugh E., Powell, Sara K., Bhatt, Aadra P., McCown, Thomas J.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 3.06 MB

english, 2017

18

Partners in Crime: Combining Oncolytic Viroimmunotherapy with Other Therapies

Suzuki, Masataka

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 381 KB

english, 2017

19

Cell Therapy for Age-Related Macular Degeneration: A New Vision for the Bone Marrow?

Ljubimov, Alexander V.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 353 KB

english, 2017

20

Systemic AAV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases

Wells, Dominic J.

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 146 KB

english, 2017

21

Showcasing Clinical Development and Production of Cellular Therapies

Levine, Bruce L., Fesnak, Andrew D., Riviere, Isabelle

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 139 KB

english, 2017

22

In This Issue

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 478 KB

english, 2017

23

Research Highlights

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 231 KB

english, 2017

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