Volume 2; Issue 6

ACS Medicinal Chemistry Letters

Volume 2; Issue 6

1

Thermodynamics of Ligand Binding and Efficiency

Reynolds, Charles H., Holloway, M. Katharine

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

2

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity

Moraski, Garrett C., Markley, Lowell D., Hipskind, Philip A., Boshoff, Helena, Cho, Sanghyun, Franzblau, Scott G., Miller, Marvin J.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 971 KB

english, 2011

3

Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate

Demont, Emmanuel H., Andrews, Benjamin I., Bit, Rino A., Campbell, Colin A., Cooke, Jason W. B., Deeks, Nigel, Desai, Sapna, Dowell, Simon J., Gaskin, Pam, Gray, James R. J.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

4

N -Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy

Amato, George, Roeloffs, Rosemarie, Rigdon, Greg C., Antonio, Brett, Mersch, Theresa, McNaughton-Smith, Grant, Wickenden, Alan D., Fritch, Paul, Suto, Mark J.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 782 KB

english, 2011

5

Peptide-Chlorambucil Conjugates Combat Pgp-Dependent Drug Efflux

Fonseca, Sonali B., Kelley, Shana O.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.96 MB

english, 2011

6

Bisdionin C—A Rationally Designed, Submicromolar Inhibitor of Family 18 Chitinases

Schüttelkopf, Alexander W., Andersen, Ole A., Rao, Francesco V., Allwood, Matthew, Rush, Christina L., Eggleston, Ian M., van Aalten, Daan M. F.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

7

Disubstituted Bis-THF Moieties as New P2 Ligands in Nonpeptidal HIV-1 Protease Inhibitors

Hohlfeld, Konrad, Tomassi, Cyrille, Wegner, Jörg Kurt, Kesteleyn, Bart, Linclau, Bruno

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

8

Potent CXCR4 Antagonists Containing Amidine Type Peptide Bond Isosteres

Inokuchi, Eriko, Oishi, Shinya, Kubo, Tatsuhiko, Ohno, Hiroaki, Shimura, Kazuya, Matsuoka, Masao, Fujii, Nobutaka

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 964 KB

english, 2011

9

Discovery of INCB3284, a Potent, Selective, and Orally Bioavailable hCCR2 Antagonist

Xue, Chu-Biao, Feng, Hao, Cao, Ganfeng, Huang, Taisheng, Glenn, Joseph, Anand, Rajan, Meloni, David, Zhang, Ke, Kong, Lingquan, Wang, Anlai, Zhang, Yingxin, Zheng, Changsheng, Xia, Michael, Chen, Lihu

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 845 KB

english, 2011

10

Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy

Landrieu, Isabelle, Hanoulle, Xavier, Fritzinger, Bernd, Horvath, Dragos, Wieruszeski, Jean-Michel, Lippens, Guy

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 866 KB

english, 2011

11

Novel Synthesis and Biological Evaluation of Enigmols as Therapeutic Agents for Treating Prostate Cancer

Garnier-Amblard, Ethel C., Mays, Suzanne G., Arrendale, Richard F., Baillie, Mark T., Bushnev, Anatoliy S., Culver, Deborah G., Evers, Taylor J., Holt, Jason J., Howard, Randy B., Liebeskind, Lanny S.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.29 MB

english, 2011

12

Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein

Thompson, Christopher F., Ali, Amjad, Quraishi, Nazia, Lu, Zhijian, Hammond, Milton L., Sinclair, Peter J., Anderson, Matt S., Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Sparr

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 932 KB

english, 2011

13

The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling

Tautermann, Christofer S., Pautsch, Alexander

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 3.65 MB

english, 2011

14

Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators

Qin, Jun, Zhou, Wei, Huang, Xianhai, Dhondi, Pawan, Palani, Anandan, Aslanian, Robert, Zhu, Zhaoning, Greenlee, William, Cohen-Williams, Mary, Jones, Nicholas, Hyde, Lynn, Zhang, Lili

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 959 KB

english, 2011

15

In This Issue, Vol. 2, Issue 6

Mahapatra, Anirban

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 979 KB

english, 2011

16

The Impact of Ionization States of Matrix Metalloproteinase Inhibitors on Docking-Based Inhibitor Design

Zhong, Haizhen, Wees, Melissa A., Faure, Theresa D., Carrillo, Carol, Arbiser, Jack, Bowen, J. Phillip

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Tor version

Z-Library

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски