Volume 3; Issue 8

ACS Medicinal Chemistry Letters

Volume 3; Issue 8

1

Brain Penetrant LRRK2 Inhibitor

Choi, Hwan Geun, Zhang, Jinwei, Deng, Xianming, Hatcher, John M., Patricelli, Matthew P., Zhao, Zheng, Alessi, Dario R., Gray, Nathanael S.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 2.80 MB

english, 2012

2

Derivatives of Heteroarylsulfonamides, Their Preparation, and Their Application in Human Therapy

Blass, Benjamin

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

3

3-Hydroxy-1-alkyl-2-methylpyridine-4(1 H )-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB

Garner, Amanda L., Struss, Anjali K., Fullagar, Jessica L., Agrawal, Arpita, Moreno, Amira Y., Cohen, Seth M., Janda, Kim D.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.95 MB

english, 2012

4

Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

Kim, Junwon, Lee, Doohyun, Park, Changmin, So, Wonyoung, Jo, Mina, Ok, Taedong, Kwon, Jeongjin, Kong, Sunju, Jo, Suyeon, Kim, Youngmi, Choi, Jihyun, Kim, Hyoung Cheul, Ko, Yoonae, Choi, Inhee, Park, Y

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

5

Antimicrobial Activity of Adenine-Based Inhibitors of NAD + -Dependent DNA Ligase

Buurman, Ed T., Laganas, Valerie A., Liu, Ce Feng, Manchester, John I.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

6

Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents

El-Elimat, Tamam, Zhang, Xiaoli, Jarjoura, David, Moy, Franklin J., Orjala, Jimmy, Kinghorn, A. Douglas, Pearce, Cedric J., Oberlies, Nicholas H.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 458 KB

english, 2012

7

Creation of Readily Accessible and Orally Active Analogue of Cortistatin A

Kotoku, Naoyuki, Sumii, Yuji, Hayashi, Takeshi, Tamura, Satoru, Kawachi, Takashi, Shiomura, Sho, Arai, Masayoshi, Kobayashi, Motomasa

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

8

Lipidated Peptidomimetics with Improved Antimicrobial Activity

Hu, Yaogang, Amin, Mohamad Nassir, Padhee, Shruti, Wang, Rongsheng E., Qiao, Qiao, Bai, Ge, Li, Yaqong, Mathew, Archana, Cao, Chuanhai, Cai, Jianfeng

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

9

Fused Heterocyclic Compounds as Ion Channel Modulators

Blass, Benjamin

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 218 KB

english, 2012

10

Target-Activated Prodrugs (TAPs) for the Autoregulated Inhibition of MMP12

Cobos-Correa, Amanda, Stein, Frank, Schultz, Carsten

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.41 MB

english, 2012

11

Substituted Benzimidazole and Imidazopyridine Compounds Useful as Cyp17 Modulators

Blass, Benjamin

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 228 KB

english, 2012

12

Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers

Harvey, Jessica H., Long, Darcie H., England, Pamela M., Whistler, Jennifer L.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012

13

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus

Tomašić, Tihomir, Šink, Roman, Zidar, Nace, Fic, Anja, Contreras-Martel, Carlos, Dessen, Andréa, Patin, Delphine, Blanot, Didier, Müller-Premru, Manica, Gobec, Stanislav, Zega, Anamarija, Kikelj, Dani

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 997 KB

english, 2012

14

Synthesis and Antitumor Activity of Ellagic Acid Peracetate

Ren, Yulin, Wei, Min, Still, Patrick C., Yuan, Shunzong, Deng, Youcai, Chen, Xiaozhuo, Himmeldirk, Klaus, Kinghorn, A. Douglas, Yu, Jianhua

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.29 MB

english, 2012

15

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects

Dvorak, Curt A., Liu, Changlu, Shelton, Jonathan, Kuei, Chester, Sutton, Steven W., Lovenberg, Timothy W., Carruthers, Nicholas I.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

16

In This Issue, Vol. 3, Issue 8

Silverman, Janice Elaine Y.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 697 KB

english, 2012

17

JAK Kinase Inhibitors as Possible Treatment for Myeloproliferative Disorders and Cancer

Abdel-Magid, Ahmed F.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 184 KB

english, 2012

18

Monitoring the Distribution of Warfarin in Blood Plasma

Rosengren, Annika M., Karlsson, Björn C. G., Nicholls, Ian A.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 391 KB

english, 2012

19

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor

Shi, Qi, Yin, Shaoman, Kaluz, Stefan, Ni, Nanting, Devi, Narra Sarojini, Mun, Jiyoung, Wang, Danzhu, Damera, Krishna, Chen, Weixuan, Burroughs, Sarah, Mooring, Suazette Reid, Goodman, Mark M., Van Mei

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 2.34 MB

english, 2012

20

Fatty Acid Synthase Inhibitors as Possible Treatment for Cancer

Abdel-Magid, Ahmed F.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 196 KB

english, 2012

21

Potassium Channel Modulators as Possible Treatment for Pain

Abdel-Magid, Ahmed F.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 207 KB

english, 2012