Volume 13; Issue 4

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Nature Chemical Biology
Volume 13; Issue 4

Nature Chemical Biology

Volume 13; Issue 4

1

HTS-compatible FRET-based conformational sensors clarify membrane receptor activation

Scholler, Pauline, Moreno-Delgado, David, Lecat-Guillet, Nathalie, Doumazane, Etienne, Monnier, Carine, Charrier-Savournin, Fabienne, Fabre, Ludovic, Chouvet, Cédric, Soldevila, Stéphanie, Lamarque, L

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

2

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Qi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chan, HoMan, Chen,

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.22 MB

english, 2017

3

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

He, Yupeng, Selvaraju, Sujatha, Curtin, Michael L, Jakob, Clarissa G, Zhu, Haizhong, Comess, Kenneth M, Shaw, Bailin, The, Juliana, Lima-Fernandes, Evelyne, Szewczyk, Magdalena M, Cheng, Dong, Klinge,

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1000 KB

english, 2017

4

Chromatin biology: Breaking into the PRC2 cage

Holoch, Daniel, Margueron, Raphaël

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 213 KB

english, 2017

5

Structure and specificity of a permissive bacterial C-prenyltransferase

Elshahawi, Sherif I, Cao, Hongnan, Shaaban, Khaled A, Ponomareva, Larissa V, Subramanian, Thangaiah, Farman, Mark L, Spielmann, H Peter, Phillips, George N, Thorson, Jon S, Singh, Shanteri

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 816 KB

english, 2017

6

A water-mediated allosteric network governs activation of Aurora kinase A

Cyphers, Soreen, Ruff, Emily F, Behr, Julie M, Chodera, John D, Levinson, Nicholas M

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

7

In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins

Schaefer, Kaitlin, Matano, Leigh M, Qiao, Yuan, Kahne, Daniel, Walker, Suzanne

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 900 KB

english, 2017

8

A tight tunable range for Ni(II) sensing and buffering in cells

Foster, Andrew W, Pernil, Rafael, Patterson, Carl J, Scott, Andrew J P, Pålsson, Lars-Olof, Pal, Robert, Cummins, Ian, Chivers, Peter T, Pohl, Ehmke, Robinson, Nigel J

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

9

Selective in vivo metabolic cell-labeling-mediated cancer targeting

Wang, Hua, Wang, Ruibo, Cai, Kaimin, He, Hua, Liu, Yang, Yen, Jonathan, Wang, Zhiyu, Xu, Ming, Sun, Yiwen, Zhou, Xin, Yin, Qian, Tang, Li, Dobrucki, Iwona T, Dobrucki, Lawrence W, Chaney, Eric J, Bopp

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

10

Evolution of a split RNA polymerase as a versatile biosensor platform

Pu, Jinyue, Zinkus-Boltz, Julia, Dickinson, Bryan C

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.72 MB

english, 2017

11

The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme

Bingaman, Jamie L, Zhang, Sixue, Stevens, David R, Yennawar, Neela H, Hammes-Schiffer, Sharon, Bevilacqua, Philip C

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

12

An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes

Italia, James S, Addy, Partha Sarathi, Wrobel, Chester J J, Crawford, Lisa A, Lajoie, Marc J, Zheng, Yunan, Chatterjee, Abhishek

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 680 KB

english, 2017

13

AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons

Gorshkov, Kirill, Mehta, Sohum, Ramamurthy, Santosh, Ronnett, Gabriele V, Zhou, Feng-Quan, Zhang, Jin

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

14

Engineering fatty acid synthases for directed polyketide production

Gajewski, Jan, Buelens, Floris, Serdjukow, Sascha, Janßen, Melanie, Cortina, Niña, Grubmüller, Helmut, Grininger, Martin

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 565 KB

english, 2017

15

Ligand-promoted protein folding by biased kinetic partitioning

Hingorani, Karan S, Metcalf, Matthew C, Deming, Derrick T, Garman, Scott C, Powers, Evan T, Gierasch, Lila M

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 434 KB

english, 2017

16

Expanding the product portfolio of fungal type I fatty acid synthases

Zhu, Zhiwei, Zhou, Yongjin J, Krivoruchko, Anastasia, Grininger, Martin, Zhao, Zongbao K, Nielsen, Jens

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 510 KB

english, 2017

17

Simultaneous quantification of protein order and disorder

Sormanni, Pietro, Piovesan, Damiano, Heller, Gabriella T, Bonomi, Massimiliano, Kukic, Predrag, Camilloni, Carlo, Fuxreiter, Monika, Dosztanyi, Zsuzsanna, Pappu, Rohit V, Babu, M Madan, Longhi, Sonia,

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

18

Protein folding: Illuminating chaperone activity

Hatters, Danny M

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 229 KB

english, 2017

19

Versatile modes of cellular regulation via cyclic dinucleotides

Krasteva, Petya Violinova, Sondermann, Holger

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 3.52 MB

english, 2017

20

Fatty acid synthases: Re-engineering biofactories

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 204 KB

english, 2017

21

Signaling: Spatial regulation of axonal cAMP

Vincent, Pierre, Castro, Liliana R

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 149 KB

english, 2017

22

Development: Marking the transition

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 102 KB

english, 2017

23

Bioconjugation: Methionine's time to shine

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 102 KB

english, 2017

24

Drug discovery: Uncoupling coupled transport

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 102 KB

english, 2017

25

Imaging: Luciferase matchmaker

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 102 KB

english, 2017