Volume 32

Nature Genetics

Volume 32

1

Erratum: Digenic inheritance of severe insulin resistance in a human pedigree

Journal:

Nature Genetics

Year:

2002

File:

PDF, 29 KB

2002

2

Growing pains

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 56 KB

english, 2002

3

Paths to the pancreas

Bort, Roque, Zaret, Ken

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

4

ATM heterozygosity and cancer risk

Concannon, Patrick

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 266 KB

english, 2002

5

Immortalizing the immortal

Cooke, Howard J.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 107 KB

english, 2002

6

TOUCHINGbase

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 179 KB

english, 2002

7

A window into the past

Relethford, John H.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 187 KB

english, 2002

8

Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae

Ottenhoff, Tom H.M., Verreck, Frank A.W., Lichtenauer-Kaligis, Elgin G.R., Hoeve, Marieke A., Sanal, Ozden, van Dissel, Jaap T.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 207 KB

english, 2002

9

Acknowledgments

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 39 KB

english, 2002

10

The tail does not always wag the dog

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

11

Bi-allelic inactivation of TCF1 in hepatic adenomas

Bluteau, Olivier, Jeannot, Emmanuelle, Bioulac-Sage, Paulette, Marqués, Juan Martin, Blanc, Jean-Frédéric, Bui, Hung, Beaudoin, Jean-Christophe, Franco, Dominique, Balabaud, Charles, Laurent-Puig, Pie

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 149 KB

english, 2002

12

Genomics for all

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

13

Blinded by the light

Jacobson, Samuel G., McInnes, Roderick R.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

14

Quorum sensing in Vibrio cholerae

Cámara, Miguel, Hardman, Andrea, Williams, Paul, Milton, Debra

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 76 KB

english, 2002

15

The pit, the cleft and the web

Muenke, Maximilian

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 560 KB

english, 2002

16

Securin a new role for itself

Rustgi, Anil K.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 91 KB

english, 2002

17

TOUCHINGbase

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

18

The nonexistence of genetic determinism

Epstein, Charles J.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

19

Top ten biotechnologies for improving health in developing countries

Daar, Abdallah S., Thorsteinsdóttir, Halla, Martin, Douglas K., Smith, Alyna C., Nast, Shauna, Singer, Peter A.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 85 KB

english, 2002

20

Risk for familial breast cancer increases with age

Hemminki, Kari, Granström, Charlotta

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 76 KB

english, 2002

21

Reply to “Risk for familial breast cancer increases with age”

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 43 KB

english, 2002

22

Erratum: Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

23

Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret

Batourina, E, Choi, C, Paragas, N, Bello, N, Hensle, T, Constantini, F D, Schuchardt, A, Bacallao, R L, Mendelsohn, C L

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

24

Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice

Hoogenraad, C C, Koekkoek, B, Akhmanova, A, Krugers, H, Dortland, B, Miedema, M, van Alphen, A, Kistler, W M, Jaegle, M, Koutsourakis, M, Camp, N Van, Verhoye, M, van der Linden, A, Kaverina, I, Grosv

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

25

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

Mikkers, H, Allen, J, Knipscheer, P, Romeyn, L, Hart, A, Vink, E, Berns, A

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

26

New genes involved in cancer identified by retroviral tagging

Suzuki, T, Shen, H, Akagi, K, Morse, H C, Malley, J D, Naiman, D Q, Jenkins, N A, Copeland, N G

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 41 KB

english, 2002

27

Erratum: A User's Guide to the Human Genome

Journal:

Nature Genetics

Year:

2002

File:

PDF, 169 KB

2002

28

The K–Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum

Howard, Heidi C., Mount, David B., Rochefort, Daniel, Byun, Nellie, Dupré, Nicolas, Lu, Jianming, Fan, Xuemo, Song, Luyan, Rivière, Jean-Baptiste, Prévost, Claude

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 719 KB

english, 2002

29

Requirement of Bmpr1a for Müllerian duct regression during male sexual development

Jamin, Soazik P., Arango, Nelson A., Mishina, Yuji, Hanks, Mark C., Behringer, Richard R.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 764 KB

english, 2002

30

A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions

Harroch, Sheila, Furtado, Glaucia C., Brueck, Wolfgang, Rosenbluth, Jack, Lafaille, Juan, Chao, Moses, Buxbaum, Joseph D., Schlessinger, Joseph

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 695 KB

english, 2002

31

Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing

Schübeler, Dirk, Scalzo, David, Kooperberg, Charles, van Steensel, Bas, Delrow, Jeffrey, Groudine, Mark

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

32

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

Wilson, Scott M., Bhattacharyya, Bula, Rachel, Rivka A., Coppola, Vincenzo, Tessarollo, Lino, Householder, Deborah B., Fletcher, Colin F., Miller, Richard J., Copeland, Neal G., Jenkins, Nancy A.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 961 KB

english, 2002

33

Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors

Zardo, Giuseppe, Tiirikainen, Maarit I., Hong, Chibo, Misra, Anjan, Feuerstein, Burt G., Volik, Stanislav, Collins, Colin C., Lamborn, Kathleen R., Bollen, Andrew, Pinkel, Daniel

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 729 KB

english, 2002

34

Uniting the paths to gene silencing

Pikaard, Craig S., Lawrence, Richard J.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

35

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

Kitamura, Kunio, Yanazawa, Masako, Sugiyama, Noriyuki, Miura, Hirohito, Iizuka-Kogo, Akiko, Kusaka, Masatomo, Omichi, Kayo, Suzuki, Rika, Kato-Fukui, Yuko, Kamiirisa, Kyoko

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 2.15 MB

english, 2002

36

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

Santoro, Raffaella, Li, Junwei, Grummt, Ingrid

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 447 KB

english, 2002

37

A role for the Rb family of proteins in controlling telomere length

García-Cao, Marta, Gonzalo, Susana, Dean, Douglas, Blasco, María A.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 341 KB

english, 2002

38

Mutation of TBCE causes hypoparathyroidism–retardation–dysmorphism and autosomal recessive Kenny–Caffey syndrome

Parvari, Ruti, Hershkovitz, Eli, Grossman, Nili, Gorodischer, Rafael, Loeys, Bart, Zecic, Alexandra, Mortier, Geert, Gregory, Simon, Sharony, Reuven, Kambouris, Marios

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 758 KB

english, 2002

39

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

Kurose, Keisuke, Gilley, Kristie, Matsumoto, Satoshi, Watson, Peter H., Zhou, Xiao-Ping, Eng, Charis

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 265 KB

english, 2002

40

The human TAS2R16 receptor mediates bitter taste in response to β-glucopyranosides

Bufe, Bernd, Hofmann, Thomas, Krautwurst, Dietmar, Raguse, Jan-Dirk, Meyerhof, Wolfgang

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 352 KB

english, 2002

41

Core-binding factor β interacts with Runx2 and is required for skeletal development

Yoshida, Carolina A., Furuichi, Tatsuya, Fujita, Takashi, Fukuyama, Ryo, Kanatani, Naoko, Kobayashi, Shinji, Satake, Masanobu, Takada, Kenji, Komori, Toshihisa

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 751 KB

english, 2002

42

A missense mutation in Tbce causes progressive motor neuronopathy in mice

Martin, Natalia, Jaubert, Jean, Gounon, Pierre, Salido, Eduardo, Haase, Georg, Szatanik, Marek, Guénet, Jean-Louis

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 961 KB

english, 2002

43

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

Suka, Noriyuki, Luo, Kunheng, Grunstein, Michael

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 942 KB

english, 2002

44

Acetylation inactivates the transcriptional repressor BCL6

Bereshchenko, Oksana R., Gu, Wei, Dalla-Favera, Riccardo

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 414 KB

english, 2002

45

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

Ang, Sonny O., Chen, Hua, Hirota, Kiichi, Gordeuk, Victor R., Jelinek, Jaroslav, Guan, Yongli, Liu, Enli, Sergueeva, Adelina I., Miasnikova, Galina Y., Mole, David

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 462 KB

english, 2002

46

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

Prokunina, Ludmila, Castillejo-López, Casimiro, Öberg, Fredrik, Gunnarsson, Iva, Berg, Louise, Magnusson, Veronica, Brookes, Anthony J., Tentler, Dmitry, Kristjansdóttir, Helga, Gröndal, Gerdur

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 175 KB

english, 2002

47

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

Casey, Graham, Neville, Phillippa J., Plummer, Sarah J., Xiang, Ying, Krumroy, Lisa M., Klein, Eric A., Catalona, William J., Nupponen, Nina, Carpten, John D., Trent, Jeffrey M.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

48

A mouse model of human L1 retrotransposition

Ostertag, Eric M., DeBerardinis, Ralph J., Goodier, John L., Zhang, Yue, Yang, Nuo, Gerton, George L., Kazazian, Haig H.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 700 KB

english, 2002

49

A myogenic differentiation checkpoint activated by genotoxic stress

Puri, Pier Lorenzo, Bhakta, Kunjan, Wood, Lauren D., Costanzo, Antonio, Zhu, Jiangyu, Wang, Jean Y. J.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.12 MB

english, 2002

50

Taking stock

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 45 KB

english, 2002

51

Chipping away at genomic medicine

Trent, Jeffrey M., Baxevanis, Andreas D.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 36 KB

english, 2002

52

Biology's century: just the beginning for microarrays

van Ingen, Chris

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 39 KB

english, 2002

53

Sharper tools and simpler methods

Duyk, Geoffrey M.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 102 KB

english, 2002

54

Microarray databases: standards and ontologies

Stoeckert, Christian J., Causton, Helen C., Ball, Catherine A.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 483 KB

english, 2002

55

Medical applications of microarray technologies: a regulatory science perspective

Petricoin, Emanuel F., Hackett, Joseph L., Lesko, Lawrence J., Puri, Raj K., Gutman, Steven I., Chumakov, Konstantin, Woodcock, Janet, Feigal, David W., Zoon, Kathryn C., Sistare, Frank D.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 104 KB

english, 2002

56

Options available—from start to finish—for obtaining data from DNA microarrays II

Holloway, Andrew J., van Laar, Ryan K., Tothill, Richard W., Bowtell, David D.L.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 513 KB

english, 2002

57

Fundamentals of experimental design for cDNA microarrays

Churchill, Gary A.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 350 KB

english, 2002

58

Microarray data normalization and transformation

Quackenbush, John

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 2.28 MB

english, 2002

59

From patterns to pathways: gene expression data analysis comes of age

Slonim, Donna K.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 152 KB

english, 2002

60

Post-analysis follow-up and validation of microarray experiments

Chuaqui, Rodrigo F., Bonner, Robert F., Best, Carolyn J.M., Gillespie, John W., Flaig, Michael J., Hewitt, Stephen M., Phillips, John L., Krizman, David B., Tangrea, Michael A., Ahram, Mamoun

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 453 KB

english, 2002

61

Characterizing the physical genome

Pollack, Jonathan R., Iyer, Vishwanath R.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.00 MB

english, 2002

62

The genetics of variation in gene expression

Cheung, Vivian G., Spielman, Richard S.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 258 KB

english, 2002

63

Protein microarrays and proteomics

MacBeath, Gavin

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 490 KB

english, 2002

64

Molecular portraits and the family tree of cancer

Chung, Christine H., Bernard, Philip S., Perou, Charles M.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 572 KB

english, 2002

65

Functional exploration of the C. elegans genome using DNA microarrays

Reinke, Valerie

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 438 KB

english, 2002

66

Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa

Chen, Mei, Kasahara, Noriyuki, Keene, Douglas R., Chan, Lawrence, Hoeffler, Warren K., Finlay, Deborah, Barcova, Maria, Cannon, Paula M., Mazurek, Constance, Woodley, David T.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 403 KB

english, 2002

67

Better therapeutics through microarrays

Gerhold, David L., Jensen, Roderick V., Gullans, Steven R.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.09 MB

english, 2002

68

Of man in mice

Athanikar, Jyoti N., Morrish, Tammy A., Moran, John V.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 172 KB

english, 2002

69

Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis

Ramoz, Nicolas, Rueda, Luis-Alfredo, Bouadjar, Bakar, Montoya, Luz-Stella, Orth, Gérard, Favre, Michel

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 305 KB

english, 2002

70

Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling

Kielman, Menno F., Rindapää, Maaret, Gaspar, Claudia, van Poppel, Nicole, Breukel, Cor, van Leeuwen, Sandra, Taketo, Makoto Mark, Roberts, Scott, Smits, Ron, Fodde, Riccardo

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.56 MB

english, 2002

71

An ACF1–ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin

Collins, Nadine, Poot, Raymond A., Kukimoto, Iwao, García-Jiménez, Custodia, Dellaire, Graham, Varga-Weisz, Patrick D.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.11 MB

english, 2002

72

Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

Ozaki, Kouichi, Ohnishi, Yozo, Iida, Aritoshi, Sekine, Akihiko, Yamada, Ryo, Tsunoda, Tatsuhiko, Sato, Hiroshi, Sato, Hideyuki, Hori, Masatsugu, Nakamura, Yusuke

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 266 KB

english, 2002

73

HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

Carpten, J.D., Robbins, C.M., Villablanca, A., Forsberg, L., Presciuttini, S., Bailey-Wilson, J., Simonds, W.F., Gillanders, E.M., Kennedy, A.M., Chen, J.D.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 580 KB

english, 2002

74

The core-binding factor β subunit is required for bone formation and hematopoietic maturation

Nuckolls, Glen H., Speck, Nancy A., Miller, Janelle, Horner, Alan, Stacy, Terryl, Lowrey, Christopher, Lian, Jane B., Stein, Gary

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 714 KB

english, 2002

75

Cbfβ interacts with Runx2 and has a critical role in bone development

Kundu, Mondira, Javed, Amjad, Jeon, Jae-Pil, Horner, Alan, Shum, Lillian, Eckhaus, Michael, Muenke, Maximilian, Lian, Jane B., Yang, Yingzi, Nuckolls, Glen H.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 2.40 MB

english, 2002

76

Long-range chromatin regulatory interactions in vivo

Carter, David, Chakalova, Lyubomira, Osborne, Cameron S., Dai, Yan-feng, Fraser, Peter

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 290 KB

english, 2002

77

Coming to terms with microarrays

Journal:

Nature Genetics

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2002

Language:

english

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PDF, 51 KB

english, 2002

78

Ch-Ch-Changes

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Nature Genetics

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2002

Language:

english

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PDF, 33 KB

english, 2002

79

Deciphering tsetse's secret partner

Wren, Brendan W.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 190 KB

english, 2002

80

Replication timing and metazoan evolution

Gilbert, David M.

Journal:

Nature Genetics

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2002

Language:

english

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PDF, 69 KB

english, 2002

81

Shining a light on photolyases

Menck, Carlos F.M.

Journal:

Nature Genetics

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2002

Language:

english

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PDF, 182 KB

english, 2002

82

Pathways of neuronal migration

Journal:

Nature Genetics

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2002

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english

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PDF, 67 KB

english, 2002

83

TOUCHINGbase

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 88 KB

english, 2002

84

The brain on microarrays

Loring, Jeanne F., Eastman, P. Scott

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 148 KB

english, 2002

85

Predicting three-dimensional genome structure from transcriptional activity

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 639 KB

english, 2002

86

Medical applications of haplotype-based SNP maps: learning to walk before we run

Lai, Eric, Bowman, Clive, Bansal, Aruna, Hughes, Arlene, Mosteller, Michael, Roses, Allen D.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 47 KB

english, 2002

87

Corrigendum: Computational identification of promoters and first exons in the human genome

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 43 KB

english, 2002

88

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

Mikkers, H, Allen, J, Knipscheer, P, Romeyn, L, Hart, A, Vink, E, Berns, A

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 43 KB

english, 2002

89

The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin

Mollet, G, Salomon, R, Gribouval, O, Silbermann, F, Bacq, D, Landthaler, G, Milford, D, Nayir, A, Rizzoni, G, Antignac, C, Saunier, S

Journal:

Nature Genetics

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2002

Language:

english

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PDF, 43 KB

english, 2002

90

What's brewing in genetic testing

Journal:

Nature Genetics

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2002

Language:

english

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PDF, 49 KB

english, 2002

91

TRAPping enhancer function

Bulger, Michael, Groudine, Mark

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 150 KB

english, 2002

92

Pluripotency and tumorigenicity

Brickman, Joshua M., Burdon, Thomas G.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 525 KB

english, 2002

93

Cellular clockwork

Nitabach, Michael N., Blau, Justin

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 400 KB

english, 2002

94

Unfolding heterochromatin for replication

de la Serna, Ivana L., Imbalzano, Anthony N.

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 1.76 MB

english, 2002

95

TOUCHINGbase

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 622 KB

english, 2002

96

Cloning debates

Journal:

Nature Genetics

Year:

2002

Language:

english

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PDF, 85 KB

english, 2002

97

Biological and biomedical implications of the co-evolution of pathogens and their hosts

Woolhouse, Mark E. J., Webster, Joanne P., Domingo, Esteban, Charlesworth, Brian, Levin, Bruce R.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 218 KB

english, 2002

98

Corrigendum: Biochemical networking contributes more to genetic buffering in human and mouse metabolic pathways than does gene duplication

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

99

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

Kurose, K, Gilley, K, Matsumoto, S, Watson, P H, Zhou, X-P, Eng, C

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

100

The K–Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum

Howard, H C, Mount, D B, Rochefort, D, Byun, N, Dupré, N, Lu, J, Fan, X, Song, L, Rivière, J-B, Prévost, C, Horst, J, Simonati, A, Lemcke, B, Welch, R, England, R, Zhan, F Q, Mercado, A, Siesser, W B,

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

101

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

Nakae, Jun, Biggs, William H., Kitamura, Tadahiro, Cavenee, Webster K., Wright, Christopher V.E., Arden, Karen C., Accili, Domenico

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.14 MB

english, 2002

102

Homozygous Tsix mutant mice reveal a sex-ratio distortion and revert to random X-inactivation

Lee, Jeannie T.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1016 KB

english, 2002

103

Distinct in vivo requirements for establishment versus maintenance of transcriptional repression

Wheeler, John C., VanderZwan, Christine, Xu, Xiaoti, Swantek, Deborah, Tracey, W. Daniel, Gergen, J. Peter

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 323 KB

english, 2002

104

Stopping transcription in its tracks

Jennings, Barbara

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

105

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

Lewis, David L., Hagstrom, James E., Loomis, Aaron G., Wolff, Jon A., Herweijer, Hans

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 310 KB

english, 2002

106

Biochemical networking contributes more to genetic buffering in human and mouse metabolic pathways than does gene duplication

Kitami, Toshimori, Nadeau, Joseph H.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 129 KB

english, 2002

107

Survival signaling mediated by c-Jun NH2-terminal kinase in transformed B lymphoblasts

Hess, Patricia, Pihan, German, Sawyers, Charles L., Flavell, Richard A., Davis, Roger J.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.26 MB

english, 2002

108

Human genome sequence variation and the influence of gene history, mutation and recombination

Reich, David E., Schaffner, Stephen F., Daly, Mark J., McVean, Gil, Mullikin, James C., Higgins, John M., Richter, Daniel J., Lander, Eric S., Altshuler, David

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

109

Mutant deoxynucleotide carrier is associated with congenital microcephaly

Rosenberg, Marjorie J., Agarwala, Richa, Bouffard, Gerard, Davis, Joie, Fiermonte, Giuseppe, Hilliard, Mark S., Koch, Thorsten, Kalikin, Linda M., Makalowska, Izabela, Morton, D. Holmes

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

110

New genes involved in cancer identified by retroviral tagging

Suzuki, Takeshi, Shen, Haifa, Akagi, Keiko, Morse, Herbert C, Malley, James D, Naiman, Daniel Q, Jenkins, Nancy A, Copeland, Neal G

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 299 KB

english, 2002

111

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

Mikkers, Harald, Allen, John, Knipscheer, Puck, Romeyn, Lieke, Hart, Augustinus, Vink, Edwin, Berns, Anton

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 477 KB

english, 2002

112

The transcriptional program of meiosis and sporulation in fission yeast

Mata, Juan, Lyne, Rachel, Burns, Gavin, Bähler, Jürg

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 561 KB

english, 2002

113

Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret

Batourina, Ekatherina, Choi, Christopher, Paragas, Neal, Bello, Natalie, Hensle, Terry, Costantini, Frank D., Schuchardt, Anita, Bacallao, Robert L., Mendelsohn, Cathy L.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1007 KB

english, 2002

114

BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair

Hartman, Anne-Renee, Ford, James M.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 533 KB

english, 2002

115

Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice

Hoogenraad, Casper C., Koekkoek, Bas, Akhmanova, Anna, Krugers, Harm, Dortland, Bjorn, Miedema, Marja, van Alphen, Arjan, Kistler, Werner M., Jaegle, Martine, Koutsourakis, Manoussos

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.60 MB

english, 2002

116

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Wechsler, Joshua, Greene, Marianne, McDevitt, Michael A., Anastasi, John, Karp, Judith E., Le Beau, Michelle M., Crispino, John D.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 434 KB

english, 2002

117

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

Robitaille, Johane, MacDonald, Marcia L.E., Kaykas, Ajamete, Sheldahl, Laird C., Zeisler, Jutta, Dubé, Marie-Pierre, Zhang, Lin-Hua, Singaraja, Roshni R., Guernsey, Duane L., Zheng, Binyou

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 480 KB

english, 2002

118

Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer

Spring, Kevin, Ahangari, Farida, Scott, Shaun P., Waring, Paul, Purdie, David M., Chen, Philip C., Hourigan, Kevin, Ramsay, Jonathan, McKinnon, Peter J., Swift, Michael

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 580 KB

english, 2002

119

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Kawaguchi, Yoshiya, Cooper, Bonnie, Gannon, Maureen, Ray, Michael, MacDonald, Raymond J., Wright, Christopher V.E.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 804 KB

english, 2002

120

A leukemogenic twist for GATA1

Look, A. Thomas

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 277 KB

english, 2002

121

Spreading the word

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

122

Power to the people

Baxevanis, Andreas D., Collins, Francis S.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 28 KB

english, 2002

123

Genomic empowerment: the importance of public databases

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 32 KB

english, 2002

124

A user's guide to the human genome

Wolfsberg, Tyra G., Wetterstrand, Kris A., Guyer, Mark S., Collins, Francis S., Baxevanis, Andreas D.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 33 KB

english, 2002

125

Introduction: putting it together

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 56 KB

english, 2002

126

Question 1 How does one find a gene of interest and determine that gene's structure? Once the gene has been located on the map, how does one easily examine other genes in that same region?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 2.25 MB

english, 2002

127

Question 2 How can sequence-tagged sites within a DNA sequence be identified?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.76 MB

english, 2002

128

Question 3 During a positional cloning project aimed at finding a human disease gene, linkage data have been obtained suggesting that the gene of interest lies between two sequence-tagged site markers. How can all the known and predicted candidate genes in this interval be identified? What BAC clones cover that particular region?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.91 MB

english, 2002

129

Question 4 A user wishes to find all the single nucleotide polymorphisms that lie between two sequence-tagged sites. Do any of these single nucleotide polymorphisms fall within the coding region of a gene? Where can any additional information about the function of these genes be found?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 754 KB

english, 2002

130

Question 5 Given a fragment of mRNA sequence, how would one find where that piece of DNA mapped in the human genome? Once its position has been determined, how would one find alternatively spliced transcripts?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 2.02 MB

english, 2002

131

Question 7 How would an investigator easily find compiled information describing the structure of a gene of interest? Is it possible to obtain the sequence of any putative promoter regions?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 832 KB

english, 2002

132

Question 8 How can one find all the members of a human gene family?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1002 KB

english, 2002

133

Question 9 Are there ways to customize displays and designate preferences? Can tracks or features be added to displays by users on the basis of their own research?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 852 KB

english, 2002

134

Question 10 For a given protein, how can one determine whether it contains any functional domains of interest? What other proteins contain the same functional domains as this protein? How can one determine whether there is a similarity to other proteins, not only at the sequence level, but also at the structural level?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.26 MB

english, 2002

135

Question 11 An investigator has identified and cloned a human gene, but no corresponding mouse ortholog has yet been identified. How can a mouse genomic sequence with similarity to the human gene sequence be retrieved?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 949 KB

english, 2002

136

Question 12 How does a user find characterized mouse mutants corresponding to human genes?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.05 MB

english, 2002

137

Question 13 A user has identified an interesting phenotype in a mouse model and has been able to narrow down the critical region for the responsible gene to approximately 0.5 cM. How does one find the mouse genes in this region?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

138

Commentary: keeping biology in mind

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 48 KB

english, 2002

139

Web resources: Internet resources featured in this guide

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 44 KB

english, 2002

140

A core nucleosome surface crucial for transcriptional silencing

Park, Jeong-Hyun, Cosgrove, Michael S., Youngman, Elaine, Wolberger, Cynthia, Boeke, Jef D.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 926 KB

english, 2002

141

Variation in gene expression within and among natural populations

Oleksiak, Marjorie F., Churchill, Gary A., Crawford, Douglas L.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 714 KB

english, 2002

142

Evidence for two apoptotic pathways in light-induced retinal degeneration

Hao, Wenshan, Wenzel, Andreas, Obin, Martin S., Chen, Ching-Kang, Brill, Elliott, Krasnoperova, Nataliia V., Eversole-Cire, Pamela, Kleyner, Yelena, Taylor, Allen, Simon, Melvin I.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.46 MB

english, 2002

143

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

Kondo, Shinji, Schutte, Brian C., Richardson, Rebecca J., Bjork, Bryan C., Knight, Alexandra S., Watanabe, Yoriko, Howard, Emma, Ferreira de Lima, Renata L.L., Daack-Hirsch, Sandra, Sander, Achim

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 440 KB

english, 2002

144

Genome sequence of the endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidia

Akman, Leyla, Yamashita, Atsushi, Watanabe, Hidemi, Oshima, Kenshiro, Shiba, Tadayoshi, Hattori, Masahira, Aksoy, Serap

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 158 KB

english, 2002

145

Mutation of TDP1, encoding a topoisomerase I–dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

Takashima, Hiroshi, Boerkoel, Cornelius F., John, Joy, Saifi, Gulam Mustafa, Salih, Mustafa A.M., Armstrong, Dawna, Mao, Yuxin, Quiocho, Florante A., Roa, Benjamin B., Nakagawa, Masanori

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.16 MB

english, 2002

146

Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1

Fitzpatrick, Galina V., Soloway, Paul D., Higgins, Michael J.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 546 KB

english, 2002

147

Chromosomal instability in ulcerative colitis is related to telomere shortening

O'Sullivan, Jacintha N., Bronner, Mary P., Brentnall, Teresa A., Finley, Jennifer C., Shen, Wen-Tang, Emerson, Scott, Emond, Mary J., Gollahon, Katherine A., Moskovitz, Alexander H., Crispin, David A.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 508 KB

english, 2002

148

An initiation site for meiotic crossing-over and gene conversion in the mouse

Guillon, Hélène, de Massy, Bernard

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

149

Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

Kapfhamer, David, Valladares, Otto, Sun, Yi, Nolan, Patrick M., Rux, John J., Arnold, Steven E., Veasey, Sigrid C., Bućan, Maja

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

150

Detection of regulatory variation in mouse genes

Cowles, Christopher R., Hirschhorn, Joel N., Altshuler, David, Lander, Eric S.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

151

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing

Kimura, Akatsuki, Umehara, Takashi, Horikoshi, Masami

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 421 KB

english, 2002

152

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

Xu, Jianfeng, Zheng, S. Lilly, Komiya, Akira, Mychaleckyj, Josyf C., Isaacs, Sarah D., Hu, Jennifer J., Sterling, David, Lange, Ethan M., Hawkins, Gregory A., Turner, Aubrey

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

153

ASPM is a major determinant of cerebral cortical size

Bond, Jacquelyn, Roberts, Emma, Mochida, Ganesh H., Hampshire, Daniel J., Scott, Sheila, Askham, Jonathan M., Springell, Kelly, Mahadevan, Meera, Crow, Yanick J., Markham, Alexander F.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 558 KB

english, 2002

154

The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin

Mollet, Géraldine, Salomon, Rémi, Gribouval, Olivier, Silbermann, Flora, Bacq, Delphine, Landthaler, Gilbert, Milford, David, Nayir, Ahmet, Rizzoni, Gianfranco, Antignac, Corinne

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 643 KB

english, 2002

155

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

Bernal, Juan A., Luna, Rosa, Espina, Águeda, Lázaro, Icíar, Ramos-Morales, Francisco, Romero, Francisco, Arias, Carmen, Silva, Augusto, Tortolero, María, Pintor-Toro, José A.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 620 KB

english, 2002

156

Genome-wide association study and mouse model identify interaction between RET and EDNRB pathways in Hirschsprung disease

Carrasquillo, Minerva M., McCallion, Andrew S., Puffenberger, Erik G., Kashuk, Carl S., Nouri, Nassim, Chakravarti, Aravinda

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 237 KB

english, 2002

157

Facioscapulohumeral muscular dystrophy is uniquely associated with one of the two variants of the 4q subtelomere

Lemmers, Richard J.L.F., de Kievit, Peggy, Sandkuijl, Lodewijk, Padberg, George W., van Ommen, Gert-Jan B., Frants, Rune R., van der Maarel, Silvère M.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

158

Mutations in PHF6 are associated with Börjeson–Forssman–Lehmann syndrome

Lower, Karen M., Turner, Gillian, Kerr, Bronwyn A., Mathews, Katherine D., Shaw, Marie A., Gedeon, Ági K., Schelley, Susan, Hoyme, H. Eugene, White, Susan M., Delatycki, Martin B., Lampe, Anne K., Cla

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 229 KB

english, 2002

159

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

Lund, Anders H., Turner, Geoffrey, Trubetskoy, Alla, Verhoeven, Els, Wientjens, Ellen, Hulsman, Danielle, Russell, Robert, DePinho, Ronald A., Lenz, Jack, van Lohuizen, Maarten

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 406 KB

english, 2002

160

Question 6 How would one retrieve the sequence of a gene, along with all annotated exons and introns, as well as a certain number of flanking bases for use in primer design?

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 983 KB

english, 2002