Volume 35; Issue 1

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Nature Genetics
Volume 35; Issue 1

Nature Genetics

Volume 35; Issue 1

1

Don't feed the hype!

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 44 KB

english, 2003

2

Erratum: A new piece of the ALS puzzle

Journal:

Nature Genetics

Year:

2003

File:

PDF, 32 KB

2003

3

An ICE pattern crystallizes

Spahn, Laura, Barlow, Denise P

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

4

An expanded role for wild-type huntingtin in neuronal transcription

Thompson, Leslie Michels

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 627 KB

english, 2003

5

Alu: a parasite's parasite?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 94 KB

english, 2003

6

TouchingBase

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

7

Research Notes

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 64 KB

english, 2003

8

Worms in L.A.

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 137 KB

english, 2003

9

A manifesto for the disenchanted

Juma, Calestous

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

10

Acknowledgments

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 39 KB

english, 2003

11

Spreading the word

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 46 KB

english, 2003

12

Power to the people

Baxevanis, Andreas D., Collins, Francis S.

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 31 KB

english, 2003

13

Genomic empowerment: the importance of public databases

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 33 KB

english, 2003

14

A user's guide to the human genome

Wolfsberg, Tyra G., Wetterstrand, Kris A., Guyer, Mark S., Collins, Francis S., Baxevanis, Andreas D.

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 33 KB

english, 2003

15

Introduction: putting it together

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 56 KB

english, 2003

16

Question 1How does one find a gene of interest and determine that gene's structure? Once the gene has been located on the map, how does one easily examine other genes in that same region?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.95 MB

english, 2003

17

Question 2How can sequence-tagged sites within a DNA sequence be identified?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 744 KB

english, 2003

18

Question 3During a positional cloning project aimed at finding a human disease gene, linkage data have been obtained suggesting that the gene of interest lies between two sequence-tagged site markers. How can all the known and predicted candidate genes in this interval be identified? What BAC clones cover that particular region?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.72 MB

english, 2003

19

Question 4A user wishes to find all the single nucleotide polymorphisms that lie between two sequence-tagged sites. Do any of these single nucleotide polymorphisms fall within the coding region of a gene? Where can any additional information about the function of these genes be found?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.26 MB

english, 2003

20

Question 5Given a fragment of mRNA sequence, how would one find where that piece of DNA mapped in the human genome? Once its position has been determined, how would one find alternatively-spliced transcripts?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.77 MB

english, 2003

21

Question 6How would one retrieve the sequence of a gene, along with all annotated exons and introns, as well as a certain number of flanking bases for use in primer design?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 2.33 MB

english, 2003

22

Question 7How would an investigator easily find compiled information describing the structure of a gene of interest? Is it possible to obtain the sequence of any putative promoter regions?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.56 MB

english, 2003

23

Question 8How can one find all the members of a human gene family?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.71 MB

english, 2003

24

Question 9Are there ways to customize displays and designate preferences? Can tracks or features be added to displays by users on the basis of their own research?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.69 MB

english, 2003

25

Question 10For a given protein, how can one determine whether it contains any functional domains of interest? What other proteins contain the same functional domains as this protein? How can one determine whether there is a similarity to other proteins, not only at the sequence level, but also at the structural level?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.18 MB

english, 2003

26

Question 11An investigator has identified and cloned a human gene, but no corresponding mouse ortholog has yet been identified. How can a mouse genomic sequence with similarity to the human gene sequence be retrieved?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.14 MB

english, 2003

27

Question 12How does a user find characterized mouse mutants corresponding to human genes?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.34 MB

english, 2003

28

Question 13A user has identified an interesting phenotype in a mouse model and has been able to narrow down the critical region for the responsible gene to approximately 0.5 cM. How does one find the mouse genes in this region?

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.77 MB

english, 2003

29

Commentary: keeping biology in mind

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 48 KB

english, 2003

30

Web resources: Internet resources featured in this guide

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 43 KB

english, 2003

31

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

Zuccato, Chiara, Tartari, Marzia, Crotti, Andrea, Goffredo, Donato, Valenza, Marta, Conti, Luciano, Cataudella, Tiziana, Leavitt, Blair R, Hayden, Michael R, Timmusk, Tõnis

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.97 MB

english, 2003

32

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors

Yvert, Gaël, Brem, Rachel B, Whittle, Jacqueline, Akey, Joshua M, Foss, Eric, Smith, Erin N, Mackelprang, Rachel, Kruglyak, Leonid

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 812 KB

english, 2003

33

LINE-mediated retrotransposition of marked Alu sequences

Dewannieux, Marie, Esnault, Cécile, Heidmann, Thierry

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.13 MB

english, 2003

34

Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase

Benson, Kathleen F, Li, Feng-Qian, Person, Richard E, Albani, Dalila, Duan, Zhijun, Wechsler, Jeremy, Meade-White, Kimberly, Williams, Kayleen, Acland, Gregory M, Niemeyer, Glenn

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.16 MB

english, 2003

35

Cidea-deficient mice have lean phenotype and are resistant to obesity

Zhou, Zhihong, Yon Toh, Shen, Chen, Zhengming, Guo, Ke, Peng Ng, Chee, Ponniah, Sathivel, Lin, Sheng-Cai, Hong, Wanjin, Li, Peng

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.86 MB

english, 2003

36

Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss

Noben-Trauth, Konrad, Zheng, Qing Yin, Johnson, Kenneth R

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 544 KB

english, 2003

37

Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica

Parkhill, Julian, Sebaihia, Mohammed, Preston, Andrew, Murphy, Lee D, Thomson, Nicholas, Harris, David E, Holden, Matthew T G, Churcher, Carol M, Bentley, Stephen D, Mungall, Karen L

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.16 MB

english, 2003

38

Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation

Awatramani, Rajeshwar, Soriano, Philippe, Rodriguez, Carolyn, Mai, Jia Jia, Dymecki, Susan M

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.35 MB

english, 2003

39

Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)

Li, Wei, Zhang, Qing, Oiso, Naoki, Novak, Edward K, Gautam, Rashi, O'Brien, Edward P, Tinsley, Caroline L, Blake, Derek J, Spritz, Richard A, Copeland, Neal G

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 3.52 MB

english, 2003

40

Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice

Roubertoux, Pierre L, Sluyter, Frans, Carlier, Michèle, Marcet, Brice, Maarouf-Veray, Fatima, Chérif, Chabane, Marican, Charlotte, Arrechi, Patricia, Godin, Fabienne, Jamon, Marc

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 640 KB

english, 2003

41

Genetic similarity and quality interact in mate choice decisions by female mice

Roberts, S Craig, Gosling, L Morris

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 108 KB

english, 2003

42

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

Ortega, Sagrario, Prieto, Ignacio, Odajima, Junko, Martín, Alberto, Dubus, Pierre, Sotillo, Rocio, Barbero, Jose Luis, Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 3.00 MB

english, 2003

43

Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12

Lin, Shau-Ping, Youngson, Neil, Takada, Shuji, Seitz, Hervé, Reik, Wolf, Paulsen, Martina, Cavaille, Jerome, Ferguson-Smith, Anne C

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 885 KB

english, 2003

44

Bared essentials of CDK2 and cyclin E

Roberts, James M, Sherr, Charles J

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

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