Volume 18; Issue 9

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Nature Medicine
Volume 18; Issue 9

Nature Medicine

Volume 18; Issue 9

1

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

Talukdar, Saswata, Oh, Da Young, Bandyopadhyay, Gautam, Li, Dongmei, Xu, Jianfeng, McNelis, Joanne, Lu, Min, Li, Pingping, Yan, Qingyun, Zhu, Yimin, Ofrecio, Jachelle, Lin, Michael, Brenner, Martin B,

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 835 KB

english, 2012

2

Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model

McIntyre, Jeremy C, Davis, Erica E, Joiner, Ariell, Williams, Corey L, Tsai, I-Chun, Jenkins, Paul M, McEwen, Dyke P, Zhang, Lian, Escobado, John, Thomas, Sophie, Szymanska, Katarzyna, Johnson, Colin

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

3

The not-so-simple HDL story: A new era for quantifying HDL and cardiovascular risk?

Heinecke, Jay W

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 2.95 MB

english, 2012

4

Tracking the insidious course of Alzheimer's disease

Liu, Zongyi, Zhou, Hanning, Agam, Gady, Viard-Gaudin, Christian

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 709 KB

english, 2012

5

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

Yipp, Bryan G, Petri, Björn, Salina, Davide, Jenne, Craig N, Scott, Brittney N V, Zbytnuik, Lori D, Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H Christopher, Malawista, Stephen E, de

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

6

Multigenerational epigenetic adaptation of the hepatic wound-healing response

Zeybel, Müjdat, Hardy, Timothy, Wong, Yi K, Mathers, John C, Fox, Christopher R, Gackowska, Agata, Oakley, Fiona, Burt, Alastair D, Wilson, Caroline L, Anstee, Quentin M, Barter, Matt J, Masson, Steve

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

7

Protect thee from the sins of thy fathers?

Friedman, Scott L

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 4.62 MB

english, 2012

8

A ROSy future for metabolic regulation of HSC division

Broxmeyer, Hal E, Mantel, Charlie

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

9

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

Van Hoecke, Annelies, Schoonaert, Lies, Lemmens, Robin, Timmers, Mieke, Staats, Kim A, Laird, Angela S, Peeters, Elke, Philips, Thomas, Goris, An, Dubois, Bénédicte, Andersen, Peter M, Al-Chalabi, Amm

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 722 KB

english, 2012

10

Thinking inside the box: how T cell inhibitory receptors signal

Haining, W Nicholas

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 11.52 MB

english, 2012

11

AIDS: Back to the beginning

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

12

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

Ito, Keisuke, Carracedo, Arkaitz, Weiss, Dror, Arai, Fumio, Ala, Ugo, Avigan, David E, Schafer, Zachary T, Evans, Ronald M, Suda, Toshio, Lee, Chih-Hao, Pandolfi, Pier Paolo

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

13

The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis?

Rader, Daniel J, Tall, Alan R

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 7.74 MB

english, 2012

14

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

Sun, Yu, Campisi, Judith, Higano, Celestia, Beer, Tomasz M, Porter, Peggy, Coleman, Ilsa, True, Lawrence, Nelson, Peter S

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.52 MB

english, 2012

15

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

Montagut, Clara, Dalmases, Alba, Bellosillo, Beatriz, Crespo, Marta, Pairet, Silvia, Iglesias, Mar, Salido, Marta, Gallen, Manuel, Marsters, Scot, Tsai, Siao Ping, Minoche, André, Somasekar, Seshagiri

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

16

The tumor microenvironment controls drug sensitivity

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 4.30 MB

english, 2012

17

Turning a new phage

Gravitz, Lauren

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

18

Technical concerns about immunoprecipitation of methylated fetal DNA for noninvasive trisomy 21 diagnosis

Tong, Yu Kwan, Chiu, Rossa Wai Kwun, Chan, Kwan Chee Allen, Leung, Tak Yeung, Lo, Yuk Ming Dennis

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 151 KB

english, 2012

19

On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions

Price, Jordan V, Tangsombatvisit, Stephanie, Xu, Guangyu, Yu, Jiangtao, Levy, Dan, Baechler, Emily C, Gozani, Or, Varma, Madoo, Utz, Paul J, Liu, Chih Long

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 2.13 MB

english, 2012

20

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion

Rangachari, Manu, Zhu, Chen, Sakuishi, Kaori, Xiao, Sheng, Karman, Jozsef, Chen, Andrew, Angin, Mathieu, Wakeham, Andrew, Greenfield, Edward A, Sobel, Raymond A, Okada, Hitoshi, McKinnon, Peter J, Mak

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 934 KB

english, 2012

21

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

McCurley, Amy, Pires, Paulo W, Bender, Shawn B, Aronovitz, Mark, Zhao, Michelle J, Metzger, Daniel, Chambon, Pierre, Hill, Michael A, Dorrance, Anne M, Mendelsohn, Michael E, Jaffe, Iris Z

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 999 KB

english, 2012

22

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

Bierhaus, Angelika, Fleming, Thomas, Stoyanov, Stoyan, Leffler, Andreas, Babes, Alexandru, Neacsu, Cristian, Sauer, Susanne K, Eberhardt, Mirjam, Schnölzer, Martina, Lasischka, Felix, Neuhuber, Winfri

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 61 KB

english, 2012

23

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

Karsten, Christian M, Pandey, Manoj K, Figge, Julia, Kilchenstein, Regina, Taylor, Philip R, Rosas, Marcela, McDonald, Jacqueline U, Orr, Selinda J, Berger, Markus, Petzold, Dominique, Blanchard, Vero

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

24

Exon-skipping drug pulls ahead in muscular dystrophy field

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

25

Straight talk with... Mark Sculpher

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

26

Reply to: Technical concerns about immunoprecipitation of methylated fetal DNA for noninvasive trisomy 21 diagnosis

Patsalis, Philippos C

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 133 KB

english, 2012

27

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Kang, Hyo Jung, Voleti, Bhavya, Hajszan, Tibor, Rajkowska, Grazyna, Stockmeier, Craig A, Licznerski, Pawel, Lepack, Ashley, Majik, Mahesh S, Jeong, Lak Shin, Banasr, Mounira, Son, Hyeon, Duman, Ronald

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1009 KB

english, 2012

28

Does a β2-adrenergic receptor–WNK4–Na-Cl co-transporter signal cascade exist in the in vivo kidney?

Uchida, Shinichi, Chiga, Motoko, Sohara, Eisei, Rai, Tatemitsu, Sasaki, Sei

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 626 KB

english, 2012

29

Anuclear neutrophils keep hunting

Peschel, Andreas, Hartl, Dominik

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 9.58 MB

english, 2012

30

Antiretroviral dynamics determines HIV evolution and predicts therapy outcome

Rosenbloom, Daniel I S, Hill, Alison L, Rabi, S Alireza, Siliciano, Robert F, Nowak, Martin A

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 834 KB

english, 2012

31

Controversial egg-producing stem cells promise better IVF

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 749 KB

english, 2012

32

The cure conundrum

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 79 KB

english, 2012

33

Obesity: Gaining SIRT-ainty

Levinson, Randy

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 298 KB

english, 2012

34

Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

Kottke, Timothy, Errington, Fiona, Pulido, Jose, Galivo, Feorillo, Thompson, Jill, Wongthida, Phonphimon, Diaz, Rosa Maria, Chong, Heung, Ilett, Elizabeth, Chester, John, Pandha, Hardev, Harrington, K

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

35

Immunology: Tweaking T cell responses

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

36

Correction

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 963 KB

english, 2012

37

Lack of BRCA testing approval creates snag for cancer trials

Azvolinsky, Anna

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 963 KB

english, 2012

38

(Meta)analyze this: Systematic reviews might lose credibility

Humaidan, Peter, Polyzos, Nikolaos P

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

39

Stop-work order creates uncertainty for Ebola drug research

Raven, Kathleen

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 86 KB

english, 2012

40

Vaccines: Protection from Nipah

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 298 KB

english, 2012

41

Drug companies look to biomarkers to salvage cancer target

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 133 KB

english, 2012

42

Cancer: Partners in crime

Farrell, Alison

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 298 KB

english, 2012

43

Drug pipeline is flush with new options for chronic constipation

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 329 KB

english, 2012

44

Institutes experiment with a variety of different appeal processes

Palmer, Roxanne

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

45

Biomedical briefing

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 532 KB

english, 2012

46

Strapped for funding, medical researchers pitch to the crowd

Hughes, Virginia

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 245 KB

english, 2012

47

Neuroscience: Disabling axonal degeneration

Da Silva, Kevin

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

48

Cancer: Awakening metastasis

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 621 KB

english, 2012

49

Consumer gene tests poised for regulatory green light

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

50

Vitamin E decreases bone mass by stimulating osteoclast fusion

Fujita, Koji, Iwasaki, Makiko, Ochi, Hiroki, Fukuda, Toru, Ma, Chengshan, Miyamoto, Takeshi, Takitani, Kimitaka, Negishi-Koga, Takako, Sunamura, Satoko, Kodama, Tatsuhiko, Takayanagi, Hiroshi, Tamai,

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

51

NIH aims to facilitate extramural research through new grants

Raven, Kathleen

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

52

Reply to: Does a β2-adrenergic receptor–WNK4–Na-Cl co-transporter signal cascade exist in the in vivo kidney?

Mu, ShengYu, Shimosawa, Tatsuo, Fujita, Toshiro

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 801 KB

english, 2012

53

New from NPG

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

54

A sweet spot to control complement-induced inflammation

Ricklin, Daniel, Reis, Edimara S, Lambris, John D

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 12.38 MB

english, 2012