Volume 13; Issue 2

Nature Reviews Drug Discovery

Volume 13; Issue 2

1

2013 FDA drug approvals

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

2

Precompetitive activity to address the biological data needs of drug discovery

Sidders, Ben, Brockel, Christoph, Gutteridge, Alex, Harland, Lee, Jansen, Peter Gildsig, McEwen, Robert, Michalovich, David, Seidel, Henrik, Weiss, Bertram, Williams-Jones, Bryn, Woodwark, Mathew

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

3

Recent patents related to PI3K

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 604 KB

english, 2014

4

Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?

Vischer, Henry F., Siderius, Marco, Leurs, Rob, Smit, Martine J.

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

5

PI3K and cancer: lessons, challenges and opportunities

Fruman, David A., Rommel, Christian

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

6

The role of ligand efficiency metrics in drug discovery

Hopkins, Andrew L., Keserü, György M., Leeson, Paul D., Rees, David C., Reynolds, Charles H.

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

7

Lead GPR40 agonist bites the dust

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

8

Regulatory watch: Where do new medicines originate from in the EU?

Lincker, Helene, Ziogas, Constantinos, Carr, Melanie, Porta, Nuria, Eichler, Hans-Georg

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 616 KB

english, 2014

9

Anticancer drugs: Curbing self-renewal of cancer-initiating cells

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 1.13 MB

english, 2014

10

Mads Krogsgaard Thomsen

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 699 KB

english, 2014

11

Neurodevelopmental disorders: The gut–microbiome–brain connection

Flight, Monica Hoyos

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 836 KB

english, 2014

12

A new roadmap for drug development for Alzheimer's disease

Becker, Robert E., Greig, Nigel H., Giacobini, Ezio, Schneider, Lon S., Ferrucci, Luigi

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 131 KB

english, 2013

13

A step closer to European clinical trial reform

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

14

Biosimilar competition: lessons from Europe

Grabowski, Henry, Guha, Rahul, Salgado, Maria

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 672 KB

english, 2014

15

Immunological disorders: Spotting the troublemakers

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 654 KB

english, 2014

16

US biomedical R&D spending declines, Asian spending soars

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

17

Kidney disease: Targeting a faulty filter

Flemming, Alexandra

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 626 KB

english, 2014

18

G protein-coupled receptors: Cloud computing gives insights into activation

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

19

Court clears the way for Nexium alternative

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 599 KB

english, 2014

20

Phenotypic screening: A more rapid route to target deconvolution

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 682 KB

english, 2014

21

Chemical genetics: Genome-wide target identification

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

22

Infectious disease: New leads for resistant tuberculosis

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

23

Anticancer drugs: A novel way to hit the proteasome

Harrison, Charlotte

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

24

In this issue

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 840 KB

english, 2014