Volume 14; Issue 2

Nature Reviews Drug Discovery

Volume 14; Issue 2

1

European regulatory experience with drugs for central nervous system disorders

Butlen-Ducuing, Florence, Zienowicz, Malgorzata, Pétavy, Frank, Haas, Manuel, Salmonson, Tomas, Eichler, Hans-Georg, Rasi, Guido

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 692 KB

english, 2014

2

The re-emergence of natural products for drug discovery in the genomics era

Harvey, Alan L., Edrada-Ebel, RuAngelie, Quinn, Ronald J.

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 540 KB

english, 2015

3

Applying thermodynamic profiling in lead finding and optimization

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

4

The history and future of targeting cyclin-dependent kinases in cancer therapy

Asghar, Uzma, Witkiewicz, Agnieszka K., Turner, Nicholas C., Knudsen, Erik S.

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 862 KB

english, 2015

5

EMA recommended approval for 40 new drugs in 2014

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 303 KB

english, 2015

6

Metabolic disease: Inhibiting serotonin reverses obesity

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 73 KB

english, 2015

7

2014 FDA drug approvals

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 734 KB

english, 2015

8

Regulatory watch: Innovation in biologic new molecular entities: 1986–2014

Miller, Kathleen L., Lanthier, Michael

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 109 KB

english, 2015

9

Market watch: Biopharma deal-making in 2014: a record year for M&A value

Micklus, Amanda, Muntner, Steven

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 150 KB

english, 2015

10

Towards the taxonomy of human disease

Hofmann-Apitius, Martin, Alarcón-Riquelme, Marta E., Chamberlain, Chris, McHale, Duncan

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 100 KB

english, 2015

11

Viral diseases: Dengue virus vaccine design

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 73 KB

english, 2015

12

Antibacterial drugs: A new drug for resistant bugs

Kåhrström, Christina Tobin

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 203 KB

english, 2015

13

Sleep-related disorders: Expanding the applications of clock-gene modulation

Kingwell, Katie

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

14

Cancer: Targeting drug-resistant melanoma

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 73 KB

english, 2015

15

Huntington Disease: Banking on ATM

Flemming, Alexandra

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 359 KB

english, 2015

16

Novartis secures first CRISPR pharma collaborations

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 303 KB

english, 2015

17

Cardiovascular disease: Insulin sensitizer protects the heart

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 134 KB

english, 2015

18

Obesity and diabetes: FXR and JAK step up to BAT

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 148 KB

english, 2015

19

A plan for sustainable funding for US biomedical research

Hensley, Preston, LaMattina, John L.

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 171 KB

english, 2015

20

Obesity: ILC2s promote browning of FAT

Crunkhorn, Sarah

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 73 KB

english, 2015

21

Zafgen charts unique path to obesity approval

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 303 KB

english, 2015

22

Randy Mills

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 218 KB

english, 2015