Volume 17; Issue 4-supp-S1

Neurobiology of Aging

Volume 17; Issue 4-supp-S1
1

An introduction

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1996
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english
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PDF, 39 KB
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2

Editorial

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1996
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3

1 A clinical and neurochemical approach to the use of diagnostic markers for Alzheimer's disease

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1996
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2 Aβ42 and Tau as Markers of Alzheimer's Disease

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1996
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3 Interpreting Cerebrospinal fluid tau levels in Alzheimer's disease

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1996
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7

14 Presenile dementia with motor neuron disease

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1996
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15 Diffuse Lewy body disease and diffuse neurofibrillary tangles with calcification

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1996
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10

17 Regional differences in senile dementia

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1996
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19 Family burden in the care of the elderly with dementia: A longitudinal study of up to 3 years

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1996
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20 Domains of sAPP involved in various aspects of its biological activity

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27 Neuroradiological features of vascular dementia

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1996
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28 Vascular dementia: Is there a link to Alzheimer's disease? Pathoanatomical considerations

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1996
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29 Is there a neurochemical link between vascular dementia and Alzheimer's disease?

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1996
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32 Mild cognitive impairment as a focus for therapeutic intervention

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1996
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33 Epidemiology of Alzheimer's disease and clues to treatment

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1996
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20

36 Two primary metabolites of GTS-21 are potent alpha7 nicotinic agonists

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1996
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21

42 The structure and molecular biology of the presenilin 2 gene

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1996
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43 The molecular biology of the presenilin-1 gene

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1996
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44 The genomic structure of the human presenilin genes

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1996
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36

75 Degenerative lesions in glucose deprived astrocytes

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1996
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89 The effect of apoptosis in cerebellar granule cells on tau

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119 Safety, tolerability and pharmacokinetics of SB 202026 in man

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1996
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125 CANDID: A unique new service providing information & support

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1996
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126 Group psychotherapy for Alzheimer-type dementia and vascular dementia

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1996
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127 Recommending treatment decisions for Alzheimer patients

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1996
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129 Home care support for people with dementia in Japan

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134 Social course of dementia across ethnic minority groups

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140 Quality of life in elderlies with dementia (1)

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141 Quality of life in elderlies with dementia (2)

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144 Evolution of Alzheimer's Disease related intraneuronal changes

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147 Cell-associated beta amyloidosis: In vivo and In vitro studies

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154 Prevalence and subtypes of dementia in Taiwan and Kinmen

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156 Protective factors for cognitive decline in a Japanese American community

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158 Genetic and environmental causes of Alzheimer's disease in twins

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169 Protein phosphatase calcineurin and dementia

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177 Update on diagnostic methods, natural ilistory, and outcome variables in Alzheimer's disease

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179 Clinical subtypes of Alzheimer's disease

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180 The caregiver's role in Alzheimer's disease

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1996
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181 Clinical profile of donepezil (E2020)

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1996
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190 Treatment of AD: Cholinesterase inhibitors or nicotinic agonists?

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1996
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194 A Scale to measure impairment in severe dementia

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199 Intellectual mental function and brain imaging features in elderly people

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211 Evolution of memory impairments in patients with Alzheimer's disease

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236 A search for susceptibility genes in late-onset Alzheimer's disease

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131

259 Neuronal dysfunction in rats infused β-amyloid protein into cerebral ventricle

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1996
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267 Spinal fluid sAPP as an index of β-amyloid in the canine brain

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298 Molecular cell biology of the neuronal cytoskeleton — The mechanisms of organelle transports

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1996
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152

300 Involvement of tau protein kinase (TPK, GSK3β) in Alzheimer's disease (AD) pathogenesis

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166

328 Apolipoprotein E / protein interactions: Developing therapeutic strategies

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330 Environmental modification of genetic mechanisms: An avenue to prevention

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334 Methodological issues

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336

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337 Metalloendopeptidase E.C.3.4.24.15 and Alzheimer's disease

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172

340 Neurotrophin signalling: Implications for neurodegeneration

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341 Neuropsin and hippocampal plasticity

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342 Prolyl endopeptidase inhibitor, JTP-4819, for Alzheimer's disease

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176

348 Mechanism of action based advantages among acetylcholinesterase inhibitors

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1996
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354 A community based epidemiological study of neurological diagnosis in pre-senile dementia

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1996
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181

358 Prediction of Aβ deposition in Hippocampus

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1996
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182

359 Mild dementia multiplies the risk of first hip fracture

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360 Contractures and loss of function in Alzheimer's disease (AD)

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361 Dental care for patients with severe dementia

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371 Diagnostic relevance of SPECT in a memory disorders clinic

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1996
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191

381 The Chicago health and aging project (CHAP): Study design and methods

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193

384 Surveying elderly female twins for Alzheimer's disease

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402 ApoE- and apoAI-containing lipoproteins in the CNS

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418 Hydrolysis of amyloid precursor protein (APP) by a brain acid protease

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1996
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421 The mechanism of amyloid β-Peptide (1–42) toxicity in PC12 cells

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1996
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440 Transgenic mice carrying presenilin and APP transgenes

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225

449 The light and shadow in the treatment of Alzheimer disease

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1996
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450 Molecular biology of prion diseases

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457 Proton magnetic resonance spectroscopy in Alzheimer's disease

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1996
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235

468 Clinical and pathological features of Parkinsonism in Alzheimer's disease

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1996
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237

475 Neuropathologic analysis of 799 cases of clinically demented patients

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1996
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238

476 Centenarian Brains: An Immunohistochemical Study

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1996
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240

479 Neurofibrillary Tangles in Peripheral Autonomic Ganglion Cells

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242

481 Eosinophilic body in the cerebral cortex of Alzheimer's disease

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498 Apolipoprotein E Genotype and Environmental Risk Factors of Dementia

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514 Quantification of in vivo phosphorylation sites of tau protein

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528 Forces in the formation of amyloid deposits

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554 Frontiers of neuronal cell biology in Alzheimer disease pathogenesis

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555 A perspective on the future Alzheimer's disease research

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559 Development of besipirdine for treatment of Alzheimer's disease

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1996
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560 Strategies for the optimal development of an anti-dementia drug

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566 Oxidative damage in Alzheimer's disease pathogenesis

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569 Long-term treatment of Alzheimer's disease with idebenone

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571 Metabolic and genetics events Involved in neuronal programmed cell death

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599 Candidate genes for Alzheimer's disease

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606 Very mild and presymptomatic Alzheimer's disease

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607 Alzheimer's disease and senile dementia of Alzheimer type

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618 Physiological aspects of β-amyloid precursor protein (β-APP) in brain

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621 The regulation of phosphorylation of Tau in SYSY neuroblastoma cells

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634 Attitudes of the caregivers of the dementing elderly - wives, daughters, and daughters in law -

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654 Midline fast waves in EEGs of elderly people with dementia

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655 Non-linear dynamical analysis of multichannel EEG in patients with Alzheimer's diseas

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657 Spatial EEG configuration of dementia patients

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661 Pupil dilation by tropicamide in Alzheimer's disease patients and probands

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695 Characterisation of AB Antibodies

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708 Loss of ryanodine receptor calcium release channels in Alzheimer's disease brain

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709 Adenylyl cyclase signal transduction in Alzheimer's disease lymphocytes

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710 Abnormality of neurofilament protein amount in Alzheimer brains

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725 Apolipyrotein E and dystrophic neurite pathology

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732 Ref-1 immunoreactivity in Alzheimer's disease

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756 Structure of tau and assembly into paired helical filaments

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761 Monomeric and dimeric Aβ in Alzheimer's disease

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383

764 A new signal transduction pathway in Alzheimer's disease

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384

765 Altered induction of Bcl-2 protein in down syndrome and AD brain

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771 Enhanced synaptic remodelling in Alzheimer disease is not dependent upon the APOE isotype

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781 Structure of the presenilin 2 gene in controls and Alzheimer cases

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804 Hallmarks of Alzheimer's disease are independent phenomena

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7 Tau and Ubiquitin as diagnostic markers of Alzheimer disease

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10 Corticobasal degeneration versus Picks' disease: An immunocytochemical comparison

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414

11 Differential diagnosis: Progressive supranuclear palsy vs postencephalitic parkinsonism

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415

12 Dementia with argyrophilic grains versus progressive supranuclear palsy

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18 Epidemiology of Alzheimer's disease: The interplay of nature and nurture

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418

23 Analysis of soluble, extracellular amyloid ß protein concentration in Alzheimer's disease

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26 Vascular factors in dementia

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422

34 Hormone therapy in dementia prevention: The women's health initiative memory Study

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37 Cytoprotective actions of nicotinic receptor stimulation

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39 Nicotinic agonists and learning in rabbits: Implications for Alzheimer's disease

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40 Nicotinic agonists prevent neuronal cell death by glutamate and amyloid beta protein

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41 Psychopharmacological effects of nicotinic agonists: An analysis of hippocampal theta waves

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54 Study of the AD3 and AD4 familial Alzheimer's disease genes

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71 Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer brains

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92 Models of age-associated free-radical brain damage

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94 Neuroprotective effects of interleukin-6 in PC12 cells

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98 Food restriction promoted development of Morris Water Mazein rat

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105 Further analysis of a cell culture model of inherited prion diseases

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108 Primer progressive aphasia: A case report

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120 Lu 25-109 — a new muscarinic agent

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472

132 The relationship between lifestyle and the deterioration of mental faculties

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476

139 Effects of daycare for senile dementias

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145 When and how does amyloid β-protein deposition start?

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151 What controls Aβ toxicity?

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152 Amyloid β protein and the cerebrovascular pathology in Alzheimer's disease

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164

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167 Neuronal death and immunosuppressant-immunophilin-transcription factor systems

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170 APP metabolism is regulated in vivo by protein kinase C in rat brain

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492

172 Molecular and cellular mechanisms of βAPP processing

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493

178 Global assessments: A crucial tool or an unworkable concept?

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495

183 Cholinergic treatment of behavioral disturbances in Alzheimer's disease

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497

185 Behavioral outcomes in clinical trials on drug therapy for Alzheimers disease

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189 G-protein mediated signal transduction disturbances in the Alzheimer's Disease brain

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196 Possible problems with clinical selection criteria used in Alzheimer's Disease clinical trials

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203 Awareness of impairments and insight into illness in Alzheimer's disease

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204 Specific errors in numeral transcoding in patients with Alzheimer's Disease

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224 Expression of presenilin 1 and 2 in human and mouse tissues

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231 Apolipoprotein E genotype and cerebral amyloid angiopathy in the elderly

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238 Apolipoprotein E genotyping by improved “affigene apoE kit”

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250 Alzheimer disease national cell repository

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261 The adrenalectomized rat as a model for neurodegeneration

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278 Unbalanced mineral/metal diets and degenerative neurological disorders

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288 The proposed new strategy of Alzheimer's disease tratment

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553

290 The effect of DHA on demented diseases

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291 Combined therapy with iron, vitamin B6, and coenzyme Q10 in 27 patients with Alzheimer disease

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302 Tau protein, phosphorylation, and microtubule stability

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557

303 Molecular dissection of the paired helical filament

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558

304 Molecular status of defined single neurons in Alzheimer's disease

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559

305 Clinico-pathological correlates in Alzheimer's disease and frontotemporal dementia

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306 Morphological and functional neuroimaging in Alzheimer's Disease

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309 What kinds of memory are preserved in Alzheimer's Disease?

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569

327 Perspectives on clinical drug trials

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329 Multiple amyloidogenic pathways — where is the therapeutic target?

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332 Early detection of Alzheimer's disease: Methods, markers and misgivings

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333 Slowing the progression of Alzheimer's disease — Clinical issues

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338 β-Amyloid, amyloid fragments and the initiation of apoptosis

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347 Clinical strategies in Alzheimer's disease: what are the pharmacological options

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349 Clinical confirmation of pre-clinical attributes: The ADENA program

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PDF, 242 KB
english, 1996
581

350 Language disturbances in Alzheimer's disease in Japanese

Year:
1996
Language:
english
File:
PDF, 113 KB
english, 1996
582

352 Autonomic failures in Alzheimer's disease and in frontotemporal dementia

Year:
1996
Language:
english
File:
PDF, 113 KB
english, 1996
591

373 Dementia in nonagerians

Year:
1996
Language:
english
File:
PDF, 142 KB
english, 1996
597

380 Projected incidence of Alzheimer's disease in the United States

Year:
1996
Language:
english
File:
PDF, 136 KB
english, 1996
601

390 APP is phosphorylated specifically in brain tissues

Year:
1996
Language:
english
File:
PDF, 248 KB
english, 1996
602

391 Possible functions of the sites covalently modified of APP in APP metabolism

Year:
1996
Language:
english
File:
PDF, 128 KB
english, 1996
603

392 The role of AβPP glycosylation state in protein processing

Year:
1996
Language:
english
File:
PDF, 128 KB
english, 1996
607

405 Tau in fibroblasts with and without the Swedish APP 670/671 mutation

Year:
1996
Language:
english
File:
PDF, 159 KB
english, 1996
615

422 β-amyloid mediated vasoactivity and vascular endothelial damage

Year:
1996
Language:
english
File:
PDF, 284 KB
english, 1996
618

425 Alternative splicing of exon 15 regulates APP conformation

Year:
1996
Language:
english
File:
PDF, 151 KB
english, 1996
620

431 Zinc promotes Aβ aggregation but attenuates Aβ neurotoxicity

Year:
1996
Language:
english
File:
PDF, 137 KB
english, 1996
624

435 Amyloid β protein disrupts bradykinin-mediated ins(1,4,5)P3

Year:
1996
Language:
english
File:
PDF, 275 KB
english, 1996
630

446 Expression of presenilin-1 in mammalian cells

Year:
1996
Language:
english
File:
PDF, 131 KB
english, 1996
636

463 Novelty P300 in dementia of Alzheimer type and multiple infarction

Year:
1996
Language:
english
File:
PDF, 151 KB
english, 1996
637

465 Negative correlation between P300 amplitude and MHPG in the cerebrospinal fluid

Year:
1996
Language:
english
File:
PDF, 133 KB
english, 1996
639

467 Lesional patterns in Parkinson's and Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 278 KB
english, 1996
651

489 Premorbid behavioral characters in demented patients

Year:
1996
Language:
english
File:
PDF, 144 KB
english, 1996
659

507 Distribution of Phosphorylated Tau in Neonatal and Adult Rat Brains

Year:
1996
Language:
english
File:
PDF, 281 KB
english, 1996
660

509 Search for inhibitors of tau-hyperphosphorylation

Year:
1996
Language:
english
File:
PDF, 143 KB
english, 1996
663

517 Deamidation and isomerization of the smeared tau in paired helical filaments

Year:
1996
Language:
english
File:
PDF, 153 KB
english, 1996
666

525 Acetylcholinesterase promotes Alzheimer's amyloid-β fibril formation

Year:
1996
Language:
english
File:
PDF, 152 KB
english, 1996
667

526 Kinetic analysis of all fibrillogenesis

Year:
1996
Language:
english
File:
PDF, 152 KB
english, 1996
678

546 Detection of wild-type and mutant forms of presenilin 1 in mammalian cell membranes

Year:
1996
Language:
english
File:
PDF, 140 KB
english, 1996
680

549 Biochemical characterization of presenilins (S182 & STM2) proteins

Year:
1996
Language:
english
File:
PDF, 137 KB
english, 1996
682

551 Transitions from normal brain aging to Alzheimer disease caleb finch

Year:
1996
Language:
english
File:
PDF, 137 KB
english, 1996
683

553 Biochemical approach to Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 140 KB
english, 1996
684

556 What is the bridging study?

Year:
1996
Language:
english
File:
PDF, 140 KB
english, 1996
686

563 Neuroinflammatory mechanisms in Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 134 KB
english, 1996
687

564 The role of inflammation in Alzheimer's disease pathogenesis

Year:
1996
Language:
english
File:
PDF, 134 KB
english, 1996
689

567 Oxidative stress and the mechanism of amyloid β-peptide toxicity

Year:
1996
Language:
english
File:
PDF, 138 KB
english, 1996
693

575 What happens when neurons encounter Aβ and secreted forms of βAPP?

Year:
1996
Language:
english
File:
PDF, 141 KB
english, 1996
694

576 Developmental prospects of antidementia drugs in Japan

Year:
1996
Language:
english
File:
PDF, 141 KB
english, 1996
698

585 Selective loss of cerebral keratan sulfate in Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 149 KB
english, 1996
702

590 Behavioral problems in Alzheimer's type, vascular and mixed dementia

Year:
1996
Language:
english
File:
PDF, 142 KB
english, 1996
706

600 Genetic analysis of familial Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 136 KB
english, 1996
710

604 Structural basis of dementia in Alzheimer's and Parkinson's diseases

Year:
1996
Language:
english
File:
PDF, 136 KB
english, 1996
711

608 The time course of lesions in aging and Alzheimer disease

Year:
1996
Language:
english
File:
PDF, 139 KB
english, 1996
713

615 Overview of the development of eptastigmine, a long acting cholinesterase inhibitor

Year:
1996
Language:
english
File:
PDF, 143 KB
english, 1996
715

617 Metrifonate in Alzheimer's disease - results of a dose-finding study

Year:
1996
Language:
english
File:
PDF, 276 KB
english, 1996
718

625 The study on trace elements in brains of dementia patients

Year:
1996
Language:
english
File:
PDF, 283 KB
english, 1996
719

626 Toxicity of β-amyloid protein: Neurochemical, histological and behavioral changes

Year:
1996
Language:
english
File:
PDF, 130 KB
english, 1996
723

631 Neurodegenerative Diseases and Model Systems

Year:
1996
Language:
english
File:
PDF, 131 KB
english, 1996
724

637 Depression in dementia

Year:
1996
Language:
english
File:
PDF, 279 KB
english, 1996
725

641 Accuracy of the clinical diagnosis of pick's disease

Year:
1996
Language:
english
File:
PDF, 268 KB
english, 1996
726

644 Different Pathology of Prion Diseases in Japan and Europe J. Tateishi T. Kitamoto

Year:
1996
Language:
english
File:
PDF, 132 KB
english, 1996
728

647 Efficacy and safety of SB 202026 as a symptomatic treatment for Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 150 KB
english, 1996
731

650 Noncholinergic agents in Alzheimer's dementia

Year:
1996
Language:
english
File:
PDF, 128 KB
english, 1996
732

651 The impact of neuroleptic medication on cognitive decline in dementia

Year:
1996
Language:
english
File:
PDF, 128 KB
english, 1996
736

663 Alzheimer's disease and computerized pupillography

Year:
1996
Language:
english
File:
PDF, 144 KB
english, 1996
745

684 ApoE genotyping as a diagnostic test in suspected Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 126 KB
english, 1996
749

688 Amyloid β-protein accumulates in the leptomeninges

Year:
1996
Language:
english
File:
PDF, 149 KB
english, 1996
759

707 Cyclin-dependent kinase 5 (cdk5) and p35 in Lewy Bodies (LB)

Year:
1996
Language:
english
File:
PDF, 153 KB
english, 1996
761

712 The role of immune disturbances in the pathogenesis of Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 138 KB
english, 1996
770

733 Calcium and energy: A unifying hypothesis of Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 143 KB
english, 1996
777

745 The LHPA axis in early Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 138 KB
english, 1996
778

746 Adrenal responsivity in mild to moderate Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 138 KB
english, 1996
796

780 The role of the presenilin 1 gene in Alzheimer's disease

Year:
1996
Language:
english
File:
PDF, 123 KB
english, 1996
802

793 GM1 ganglioside-bound amyloid ß-protein: A possible form of preamyloid

Year:
1996
Language:
english
File:
PDF, 135 KB
english, 1996
804

795 Post-secretory catabolism of ß-amyloid in brain

Year:
1996
Language:
english
File:
PDF, 272 KB
english, 1996
808

806 Causes and consequences of neuronal energy deficit

Year:
1996
Language:
english
File:
PDF, 255 KB
english, 1996
809

807 Evidence supporting the inflammatory hypothesis of Alzheimer disease

Year:
1996
Language:
english
File:
PDF, 121 KB
english, 1996
811

Author index

Year:
1996
File:
PDF, 1022 KB
1996