Volume 10; Issue 2

Organic Process Research & Development

Volume 10; Issue 2

1

Catalytic Mesylation of Alcohols: A Highly Productive Process for Trifluoroethyl Mesylate

Vastra, Johann, Saint-Jalmes, Laurent

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

2

A Well-Behaved Crystallisation of a Pharmaceutical Compound

Black, Simon N., Quigley, Kathryn, Parker, Alexandra

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 167 KB

english, 2006

3

Green Chemistry, a Pharmaceutical Perspective

Tucker, John L.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 34 KB

english, 2006

4

Stereoselective Process for a CCR3 Antagonist

Yue, Tai-Yuen, McLeod, Douglas D., Albertson, Kevin B., Beck, Steven R., Deerberg, Joerg, Fortunak, Joseph M., Nugent, William A., Radesca, Lilian A., Tang, Liya, Xiang, Cathie Dong

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

5

Nearly Chromatography-Free Synthesis of the A 3 B-Porphyrin 5-(4-Hydroxymethylphenyl)-10,15,20-tri- p -tolylporphinatozinc(II)

Zaidi, Syeda Huma H., Loewe, Robert S., Clark, Brad A., Jacob, Marc J., Lindsey, Jonathan S.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 264 KB

english, 2006

6

Unusual Inhibition Effect of 1-(1-Naphthyl)-1-methylethylhydroperoxide on the Liquid-Phase Oxidation of Isopropylarenes. GC−MS and Theoretical Studies of the Thermal Decomposition of 1-Naphthyl- and 1-Anthryl-1-methylethylhydroperoxides

Mazurkiewicz, Roman, Zawadiak, Jan, Orlińska, Beata, Hefczyc, Barbara, Stec, Zbigniew, Grymel, Mirosława, Fiedorow, Piotr, Koroniak, Henryk

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

7

Regioselective Synthesis of an Imidazo[4,5- c ]pyridine through Selective Acylation of 3,4-Diaminopyridine: Synthesis of CP-885,316

Caron, Stéphane, Do, Nga M., McDermott, Ruth E., Bahmanyar, S.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

8

A New and Direct Asymmetric Synthesis of a Hindered Chiral Amine via a Novel Sulfinate Ketimine Derived from N -Tosyl-1,2,3-oxathiazolidine-2-oxide: Practical Asymmetric Synthesis of ( R )-Sibutramine

Han, Zhengxu, Krishnamurthy, Dhileepkumar, Senanayake, Chris H.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

9

A High Yield and Pilot-Scale Process for the Preparation of Adapalene

Liu, Zhichang, Xiang, Jiannan

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 47 KB

english, 2006

10

Development of a Scalable Synthetic Process for Selective Bromination of 4-Methyl-3,7-Substituted Coumarins

Li, Xun, Jain, Nareshkumar, Russell, Ronald K., Ma, Robert, Branum, Shawn, Xu, Jiayi, Sui, Zhihua

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 81 KB

english, 2006

11

Isomerization-Free Sulfonylation and Its Application in the Synthesis of PHA-565272A

Fleck, Thomas J., Chen, Jiong Jack, Lu, Cuong V., Hanson, Kari J.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

12

Development of a Scalable Synthesis to VEGFR Inhibitor AG-28262

Scott, Robert W., Neville, Sean N., Urbina, Armando, Camp, David, Stankovic, Nebojsa

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 96 KB

english, 2006

13

Continuous Hydrogenation of 2-Butyne-1,4-diol to 2-Butene- and Butane-1,4-diols

Rode, C. V., Tayade, P. R., Nadgeri, J. M., Jaganathan, R., Chaudhari, R. V.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

14

Studies of Copper−Bisoxazoline-Catalyzed Asymmetric Cyclopropanation of 2,5-Dimethyl-2,4-hexadiene

Itagaki, Makoto, Masumoto, Katsuhisa, Suenobu, Katsuhiro, Yamamoto, Yohsuke

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

15

Practical Synthesis of 2-Amino-5-fluorothiazole Hydrochloride

Briner, Paul H., Fyfe, Matthew C. T., Martin, Pierre, Murray, P. John, Naud, Frédéric, Procter, Martin J.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 33 KB

english, 2006

16

Good Pharmaceutical Manufacturing Practice: Rationale and Compliance By John Sharp. CRC Press: London, UK. 2005. 503 pp. List price $229.95 (Web price $207). ISBN 0-8493-1944-3.

Robinson, Derek

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 9 KB

english, 2006

17

(2-Acetoxyphenoxy)ethyl (APOE) as a Phosphate Protecting Group in Solid-Phase Synthesis of Oligonucleotides via the Phosphoramidite Approach

Cheruvallath, Zacharia S., Eleuteri, Alessandra, Turney, Brett, Ravikumar, Vasulinga T.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

18

Safety Improvement of Chemical Processes Involving Azides by Online Monitoring of the Hydrazoic Acid Concentration

Wiss, Jacques, Fleury, Christian, Onken, Ulrich

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 274 KB

english, 2006

19

A Practical Synthesis of the Pseudotripeptide RC-1291

Paul, Bernhard J., Littler, Benjamin J., Jos, Frederic, Vogt, Paul F., Pines, Seemon H.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

20

On Using Tree Analysis to Quantify the Material, Input Energy, and Cost Throughput Efficiencies of Simple and Complex Synthesis Plans and Networks: Towards a Blueprint for Quantitative Total Synthesis and Green Chemistry

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 1.05 MB

english, 2006

21

Handbook of Reagents for Organic Synthesis: Reagents for Glycoside, Nucleotide and Peptide Synthesis Edited by D. Crich. Wiley: New York. 2005. 770 + xiv pp. £80. ISBN 0-470-02304-X.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 14 KB

english, 2006

22

Organic Reactions, Volume 65 Edited by L. E. Overman. John Wiley & Sons: Hoboken, NJ. 2005. 627 + vii pp. £74.50. ISBN: 0-471-68260-8.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 6 KB

english, 2006

23

Development of a Practical High-Yield Industrial Synthesis of Pergolide Mesylate

Cabri, Walter, Roletto, Jacopo, Olmo, Sara, Fonte, Piera, Ghetti, Paolo, Songia, Simonetta, Mapelli, Elio, Alpegiani, Marco, Paissoni, Paolo

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

24

A Review of U.S. Patents in the Field of Organic Process Development Published during November and December 2005

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

25

Recent Uses of Sol−Gel Doped Catalysts in the Fine Chemicals and Pharmaceutical Industry

Ciriminna, Rosaria, Pagliaro, Mario

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 441 KB

english, 2006

26

Oh Oh Oh. What a Referee! 1

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 15 KB

english, 2006

27

Polymorph and Particle Size Control of PPAR Compounds PF00287586 and AG035029

Kline, Billie J., Saenz, James, Stanković, Nebojša, Mitchell, Mark B.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 1.18 MB

english, 2006

28

Development of a Pilot-Scale Preparation of N -[[(5S)-3-[4-(1,1-Dioxido-4- thiomorpholinyl)-3,5-difluorophenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, PNU-288034, an Oxazolidinone Antibacterial Agent

Lu, Cuong V., Chen, Jiong J., Perrault, William R., Conway, Brian G., Maloney, Mark T., Wang, Ying

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

29

Some Items of Interest to Process R&D Chemists and Engineers

McLaughlin, Mark, García Rubio, Silvina, Tilstam, Ulf, Antunes, Octavio Augusto Ceva, Laird, Trevor, Yadav, Ganapati D., Zlota, Andrei

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 362 KB

english, 2006

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