Volume 11; Issue 5

Organic Process Research & Development

Volume 11; Issue 5

1

A Scaleable Synthesis of Methyl 3-Amino-5-(4-fluorobenzyl)-2-pyridinecarboxylate

Boros, Eric E., Burova, Svetlana A., Erickson, Greg A., Johns, Brian A., Koble, Cecilia S., Kurose, Noriyuki, Sharp, Matthew J., Tabet, Elie A., Thompson, James B., Toczko, Matthew A.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 97 KB

english, 2007

2

Convergent Approach for Commercial Synthesis of Gefitinib and Erlotinib

Chandregowda, Venkateshappa, Venkateswara Rao, Gudapati, Chandrasekara Reddy, Goukanapalli

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 124 KB

english, 2007

3

An Improved Synthesis of Rimonabant: Anti-Obesity Drug #

Kotagiri, Vijay Kumar, Suthrapu, Sashikanth, Mukunda Reddy, Jambula, Prasad Rao, Chitneni, Bollugoddu, Vijaybhaskar, Bhattacharya, Apurba, Bandichhor, Rakeshwar

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

4

A Scaleable Synthesis of Dutasteride: A Selective 5α-Reductase Inhibitor †

Satyanarayana, Komati, Srinivas, Katkam, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 132 KB

english, 2007

5

Reduction of Ethyl Benzoylacetate and Selective Protection of 2-(3-Hydroxy-1-phenylpropyl)-4-methylphenol: A New and Facile Synthesis of Tolterodine

De Castro, Kathlia A., Ko, Jungnam, Park, Daejong, Park, Sungdae, Rhee, Hakjune

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

6

A High-Throughput Process for Valsartan

Beutler, Ulrich, Boehm, Matthias, Fuenfschilling, Peter C., Heinz, Thomas, Mutz, Jean-Paul, Onken, Ulrich, Mueller, Martin, Zaugg, Werner

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

7

A Concise Synthesis of a Novel Insulin-Like Growth Factor I Receptor (IGF-IR) Inhibitor †

Slade, Joel, Bajwa, Joginder, Liu, Hui, Parker, David, Vivelo, James, Chen, Guang-Pei, Calienni, John, Villhauer, Edwin, Prasad, Kapa, Repič, Oljan, Blacklock, Thomas J.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

8

New Synthetic Approach to Memantine Hydrochloride starting from 1,3-Dimethyl-adamantane

Madhra, Mukesh K., Sharma, Mukesh, Khanduri, C. H.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

9

Regulatory Highlights for January to August 2007

Robinson, Derek

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 74 KB

english, 2007

10

Industrial Biotransformations, 2nd Completely Revised and Extended Edition. A. Liese , K. Seelbach , and C. Wandrey , Eds. Wiley-VCH : Weinheim . 2006 . 556 + xiv pp. £149.00. ISBN 3-527-31001-0 .

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

11

A Review of U.S. Patents in the Field of Organic Process Development Published During April and May 2007

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 333 KB

english, 2007

12

Characterization of the Polymorphic Behavior of an Organic Compound Using a Dynamic Thermal and X-ray Powder Diffraction Technique

Albers, David, Galgoci, Michelle, King, Dan, Miller, Daniel, Newman, Robert, Peerey, Linda, Tai, Eva, Wolf, Richard

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 3.72 MB

english, 2007

13

Purification of Difluoromethylornithine by Global Process Optimization: Coupling of Chemistry and Chromatography with Enantioselective Crystallization

Perrin, Scott R., Hauck, Wilhelm, Ndzie, Elias, Blehaut, Jean, Ludemann-Hombouger, Olivier, Nicoud, Roger-Marc, Pirkle, William H.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

14

Kinetics for Scale-Up of a One-Pot Pathway to 5-(3-Fluorophenyl)-2,4-dihydro-2,4-dimethyl-3 H -1,2,4-triazole-3-thione Using a Hybrid Model of Parallel and Consecutive Reactions

Louks, David H., Stolz-Dunn, Sandra K.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 661 KB

english, 2007

15

Green Chemical Synthesis of 2-Benzenesulfonyl-pyridine and Related Derivatives

Trankle, William G., Kopach, Michael E.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

16

The Art of Drug Synthesis. By Douglas S. Johnson and Jie Jack Li . Wiley-Interscience: New York . 2007 . 276 pp. £50.50, $89.95. ISBN 978-0-471-75215-8 .

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

17

Enantioselective Organocatalysis: Reactions and Experimental Procedures . Edited by Peter I. Dalko . Wiley-VCH : Weinheim . 2007 . 536 + xxiii pp. $190.00. ISBN 978-3-527-31522-2 .

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

18

A Chemoenzymatic Synthesis of an Androgen Receptor Antagonist ‡

Vaidyanathan, Rajappa, Hesmondhalgh, Lynsey, Hu, Shanghui

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 92 KB

english, 2007

19

Common Fragrance and Flavor Materials: Preparation, Properties and Uses, 5th ed. By Horst Surburg and Johannes Panten . Wiley-VCH Verlag GmbH: Weinheim . 2006. 318 + xii pp. Euro 139.00. ISBN 3-527-31315-X.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

20

Some Items of Interest to Process R&D Chemists and Engineers

McLaughlin, Mark, Rubio, Silvina García, Pfeiffer, Matthew, Tilstam, Ulf, Mathen, Joseph Swaroop, Antunes, Octavio Augusto Ceva, Laird*, Trevor, Zlota, Andrei A.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 299 KB

english, 2007

21

Intellectual Property Management: A Guide for Scientists, Engineers, Financiers, and Managers. By Claas Junghans , Adam Levy , Rolf Sander , and Tobias Boeckh . Wiley-VCH Verlag GmbH : Weinheim. 2006. 170 + xviii pp. Euro 49.90. ISBN 3-527-31286-2.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

22

An Alternate Route to 2-Amino-3-nitro-5-bromo-4-picoline: Regioselective Pyridine Synthesis via 2-Nitramino-picoline Intermediate

Bhattacharya, Apurba, Purohit, Vikram C., Deshpande, Prashant, Pullockaran, Annie, Grosso, John A., DiMarco, John D., Gougoutas, Jack Z.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 199 KB

english, 2007

23

A Novel, Safe, and Robust Nitration Process for the Synthesis of 4-(4-Methoxy-3-nitrophenyl)morpholine

Zhang, Pingsheng, Shankar, Ashish, Cleary, Thomas P., Cedilote, Miall, Locklear, Dobbert, Pierce, Michael E.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 87 KB

english, 2007

24

Vanishing Microwave Effects: Influence of Heterogeneity

Dressen, Mark H. C. L., Kruijs, Bastiaan H. P. van de, Meuldijk, Jan, Vekemans, Jef A. J. M., Hulshof, Lumbertus A.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 742 KB

english, 2007

25

Practical Alternative Synthesis of 1-(8-Fluoro-naphthalen-1-yl)piperazine

Zhu, Zhijian, Colbry, Norm L., Lovdahl, Mark, Mennen, Kenneth E., Acciacca, Alison, Beylin, Vladimir G., Clark, Jerry D., Belmont, Daniel T.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 83 KB

english, 2007

26

Organic Synthesis – State of the Art 2003–2005. By Douglass F. Taber . Wiley-Interscience : New York . 2006 . 216 pp. $99.95. ISBN 0-470-05331-3.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

27

Mobile Tool for HPLC Reaction Monitoring

Schafer, Wes A., Hobbs, Steve, Rehm, Jason, Rakestraw, David A., Orella, Charles, McLaughlin, Mark, Ge, Zhihong, Welch, Christopher J.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

28

March’s Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 6th ed. By Michael B. Smith and Jerry March . Wiley Interscience : New York. 2007 . 2357 + xx pp. £58.95 (hardback). ISBN 13 978-0-471-72091-1, ISBN 10 0-471-72091-7 .

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

29

Process Intensification for Substrate-Coupled Whole Cell Ketone Reduction by In Situ Acetone Removal

Schroer, Kirsten, Tacha, Eva, Lütz, Stephan

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

30

A Synthesis Is Not the Same as a Process

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 42 KB

english, 2007

31

Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-aza-5-androstene-17-carboxylate, A Key Intermediate for Finasteride and Dutasteride #

Karrothu, Srihari Babu, Kolla, Naveenkumar, Lekkala, Amarnath Reddy, Golla, China Malakondaiah, Vijaya Anand, Ramasamy, Gandu, Venkateswarlu, Bhattacharya, Apurba, Padi, Pratap Reddy, Bandichhor, Rake

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 83 KB

english, 2007

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