Volume 16; Issue 9

Organic Process Research & Development

Volume 16; Issue 9

1

Development of a Practical and Scalable Synthesis of ( R )- and ( S )-3-Amino-2-[(benzyloxy)methyl]propan-1-ol Monohydrochloride: A Useful C-4 Chiral Building Block

Yoshida, Shinya, Obitsu, Kazuyoshi, Hayashi, Yasumasa, Shibazaki, Mitsuyoshi, Kimura, Takenori, Takahashi, Takumi, Asano, Toru, Kubota, Hirokazu, Mukuta, Takashi

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 628 KB

english, 2012

2

New and Efficient Synthetic Approaches for the Regioisomeric and Iminium Impurities of Clopidogrel Bisulfate

Aalla, Sampath, Gilla, Goverdhan, Anumula, Raghupathi Reddy, Charagondla, Kavitha, Vummenthala, Prabhakar Reddy, Padi, Pratap Reddy

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

3

Determination of Optimal Operation Conditions for Production of Cephalosporin G from Penicillin G Potassium

Salehpour, Pooneh, Yegani, Reza, Hajmohammadi, Reza

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

4

Selection and Scale-Up Evaluation of an Alternative Route to (−)-(3 R ,4 R )-1-Benzyl-4-(benzylamino)piperidin-3-ol

Young, Ian S., Ortiz, Adrian, Sawyer, James R., Conlon, David A., Buono, Frederic G., Leung, Simon W., Burt, Justin L., Sortore, Eric W.

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 560 KB

english, 2012

5

A Novel Method for the Large Scale Synthesis of Cinacalcet Hydrochloride Using Iron Catalyzed C–C Coupling

Tewari, Neera, Maheshwari, Nitin, Medhane, Roshan, Nizar, Hashim, Prasad, Mohan

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

6

Applied Homogeneous Catalysis Applied Homogeneous Catalysis . By ArnoBehr and PeterNeubert. Wiley-VCH , Weinheim , 2012 . 688 + XXVII pp. €69. ISBN 978-3-527-32633-4 .

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 110 KB

english, 2012

7

Science of Synthesis Workbench Edition: Water in Organic Synthesis Science of Synthesis Workbench Edition: Water in Organic Synthesis . Edited by ShuKobayashi. Thieme : Stuttgart, Germany . 2012 . pp 960 + l. $299; €249. ISBN 978-3-13-169351-8 .

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

8

Practical Process Research and Development - A Guide For Organic Chemists Practical Process Research and Development - A Guide For Organic Chemists , 2nd ed. By Neal G. Anderson . Academic Press : New York , 2012 . 416 pages. Price $125, €89.95, £75.99. ISBN 978-0-12-386537-3 .

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 110 KB

english, 2012

9

Application-Oriented Analysis of Mixing Performance in Microreactors

Schwolow, Sebastian, Hollmann, Jutta, Schenkel, Berthold, Röder, Thorsten

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 597 KB

english, 2012

10

Some Items of Interest to Process R&D Chemists and Engineers

McLaughlin, Mark, Widegren, Magnus, Paul, Soumendu, Ramirez, Antonio, Richardson, Paul, Zlota, Andrei, Knight, John

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 829 KB

english, 2012

11

A Review of U.S. Patents in the Field of Organic Process Development Published During April and May 2012

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 977 KB

english, 2012

12

Development of a Practical and Scalable Synthesis of a Potent CRTH2 Antagonist

Yoshida, Shinya, Yoshino, Toshitaka, Miyafuji, Akio, Yasuda, Hironobu, Kimura, Takenori, Takahashi, Takumi, Mukuta, Takashi

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 731 KB

english, 2012

13

Scale-Up Synthesis of Antidepressant Drug Vilazodone

Hu, Bin, Song, Qiao, Xu, Yungen

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 355 KB

english, 2012

14

Solid State NMR: Basic Principles and Practice Solid State NMR: Basic Principles and Practice. By David C. Apperley , Robin K. Harris , and Paul Hodgkinson . Momentum Press LLC : New York , 2012 . ISBN: 978-1-60650-350-8 . 276 pages (including indices). $109.95.

Knight, John, Knight, Michael

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 112 KB

english, 2012

15

Greener Writing: Higher-Quality Content and Fewer Wasted Words

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 117 KB

english, 2012

16

An Asymmetric Synthesis of a Chiral Sulfone Acid with Concomitant Hydrolysis and Oxidation to Enable the Preparation of a Glucokinase Activator

DeBaillie, Amy C., Magnus, Nicholas A., Laurila, Michael E., Wepsiec, James P., Ruble, J. Craig, Petkus, Jeffrey J., Vaid, Radhe K., Niemeier, Jeffry K., Mick, Joseph F., Gunter, Thomas Z.

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 340 KB

english, 2012

17

Inclusion of Environmental Impact Parameters in Radial Pentagon Material Efficiency Metrics Analysis: Using Benign Indices as a Step Towards a Complete Assessment of “Greenness” for Chemical Reactions and Synthesis Plans

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 3.41 MB

english, 2012

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