Volume 21; Issue 4

Organic Process Research & Development

Volume 21; Issue 4

1

Characterization of Milli- and Microflow Reactors: Mixing Efficiency and Residence Time Distribution

Gobert, Sven R. L., Kuhn, Simon, Braeken, Leen, Thomassen, Leen C. J.

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 2.64 MB

english, 2017

2

Amalgamation of Synthetic Biology and Chemistry for High-Throughput Nonconventional Synthesis of the Antimalarial Drug Artemisinin

Singh, Dharmendra, McPhee, Derek, Paddon, Christopher J., Cherry, Joel, Maurya, Ghanshyam, Mahale, Ganesh, Patel, Yogesh, Kumar, Neeraj, Singh, Subhash, Sharma, Brajesh, Kushwaha, Lavkesh, Singh, Sati

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 476 KB

english, 2017

3

Downstream Processability of Crystal Habit-Modified Active Pharmaceutical Ingredient

Pudasaini, Nawin, Upadhyay, Pratik P., Parker, Christian R., Hagen, Stefan U., Bond, Andrew D., Rantanen, Jukka

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 2.61 MB

english, 2017

4

Recycling of Analytical Grade Solvents on a Lab Scale with a Purpose-Built Temperature-Controlled Distillation Unit

Zweckmair, Thomas, Hell, Slavica, Klinger, Karl Michael, Rosenau, Thomas, Potthast, Antje, Böhmdorfer, Stefan

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 365 KB

english, 2017

5

Thermal Safety Assessment through the Concept of Structure–Reactivity: Application to Vegetable Oil Valorization

Leveneur, Sébastien

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 922 KB

english, 2017

6

Synthesis of Trelagliptin Succinate

Xu, Shenghui, Hao, Qun, Li, Hongyan, Liu, Zhenren, Zhou, Weicheng

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 369 KB

english, 2017

7

Real-Time Image Processing Based Online Feedback Control System for Cooling Batch Crystallization

Borsos, Ákos, Szilágyi, Botond, Agachi, Paul Şerban, Nagy, Zoltán K.

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

8

Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients

Arribas Bueno, Raquel, Crowley, Clare M., Hodnett, Benjamin K., Hudson, Sarah, Davern, Peter

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 9.42 MB

english, 2017

9

Synthesis of Urea Derivatives in Two Sequential Continuous-Flow Reactors

Bana, Péter, Lakó, Ágnes, Kiss, Nóra Zsuzsa, Béni, Zoltán, Szigetvári, Áron, Kóti, János, Túrós, György István, Éles, János, Greiner, István

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 575 KB

english, 2017

10

Development of Commercial-Ready Processes for Antibody Drug Conjugates

Hu, Xi, Bortell, Eric, Kotch, Frank W., Xu, April, Arve, Bo, Freese, Stephen

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

11

Correction to “Development of a Scalable Process for the Synthesis of DNDI-VL-2098: A Potential Preclinical Drug Candidate for the Treatment of Visceral Leishmaniasis”

Satam, Vijay S., Pedada, Srinivasa Rao, Kandadai, Srinivas A., Kamaraj, Pasumpon, Antao, Nakita, Singh, Apoorva, Hindupur, Rama Mohan, Pati, Hari N., Thompson, Andrew M., Launay, Delphine, Martin, Den

Journal:

Organic Process Research & Development

Year:

2017

File:

PDF, 128 KB

2017

12

Sustainability Improvements through Catalyst Recycling in a Liquid–Liquid Batch and Continuous Phase Transfer Catalyzed Process

Teoh, Soo Khean, Toh, Qiao Yan, Noorulameen, Mohammad Salih, Sharratt, Paul N.

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

13

Impact Is Important—Systematic Investigation of the Influence of Milling Balls in Mechanochemical Reactions

Fischer, Franziska, Fendel, Nicole, Greiser, Sebastian, Rademann, Klaus, Emmerling, Franziska

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 719 KB

english, 2017

14

Process Development and Good Manufacturing Practice Production of a Tyrosinase Inhibitor via Titanium-Mediated Coupling between Unprotected Resorcinols and Ketones

Gerfaud, Thibaud, Martin, Cédric, Bouquet, Karinne, Talano, Sandrine, Millois-Barbuis, Corinne, Musicki, Branislav, Boiteau, Jean-Guy, Cardinaud, Isabelle

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 596 KB

english, 2017

15

Selective Oxidation of Benzylic C–H Using Nanoscale Graphene Oxide as Highly Efficient Carbocatalyst: Direct Synthesis of Terephthalic Acid

Heidari, Masoud, Sedrpoushan, Alireza, Mohannazadeh, Farajollah

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.80 MB

english, 2017

16

Use of Programmed Damped Temperature Cycles for the Deracemization of a Racemic Suspension of a Conglomerate Forming System

Suwannasang, Kittisak, Flood, Adrian E., Rougeot, Celine, Coquerel, Gerard

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 2.23 MB

english, 2017

17

Practical Large-Scale Regioselective Zincation of Chromone Using TMPZnCl·LiCl Triggered by the Presence or Absence of MgCl 2

Klier, Lydia, Ziegler, Dorothée S., Rahimoff, René, Mosrin, Marc, Knochel, Paul

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

18

Recent Advances in Nonaqueous Extraction of Bitumen from Mineable Oil Sands: A Review

Lin, Feng, Stoyanov, Stanislav R., Xu, Yuming

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

19

Removal of Endocrine Disrupting Chemicals in Wastewater by Enzymatic Treatment with Fungal Laccases

Becker, Dennis, Rodriguez-Mozaz, Sara, Insa, Sara, Schoevaart, Rob, Barceló, Damià, de Cazes, Matthias, Belleville, Marie-Pierre, Sanchez-Marcano, José, Misovic, Andrea, Oehlmann, Jörg, Wagner, Martin

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

20

From R&D to Clinical Supplies

Prashad, Amar S., Nolting, Birte, Patel, Vimalkumar, Xu, April, Arve, Bo, Letendre, Leo

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

21

Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole

Han, Chong, Green, Keena, Pfeifer, Eugen, Gosselin, Francis

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 429 KB

english, 2017

22

Development of an Efficient and Scalable Biocatalytic Route to (3 R )-3-Aminoazepane: A Pharmaceutically Important Intermediate

Feng, Yahui, Luo, Zhonghua, Sun, Guodong, Chen, Minghong, Lai, Jinqiang, Lin, Wei, Goldmann, Siegfried, Zhang, Lei, Wang, Zhongqing

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 495 KB

english, 2017

23

Development and Scale-up of a Flow Chemistry Lithiation–Borylation Route to a Key Boronic Acid Starting Material

Usutani, Hirotsugu, Nihei, Takashi, Papageorgiou, Charles D., Cork, David G.

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 429 KB

english, 2017

24

Some Items of Interest to Process R&D Chemists and Engineers

Zhao, Wenyi, Zhao, Dongbo, Guizzetti, Sylvain, Schwindeman, James A., Daniels, David S. B., Guerrero, Carlos, Kargbo, Robert, Raghuraman, Arjun, Knight, John

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 2.63 MB

english, 2017

25

Editorial

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 110 KB

english, 2017

26

Issue Publication Information

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 157 KB

english, 2017

27

Issue Editorial Masthead

Journal:

Organic Process Research & Development

Year:

2017

Language:

english

File:

PDF, 156 KB

english, 2017

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