Volume 6; Issue 5

Organic Process Research & Development

Volume 6; Issue 5

1

Scale-Up Synthesis of the Dopamine Uptake Inhibitor GBR-12909

Ironside, Michael D., Sugathapala, Priyantha M., Robertson, Jerod, Darey, Mark C. P., Zhang, Jianzhong

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 144 KB

english, 2002

2

An Optimized Process for Formation of 2,4-Disubstituted Imidazoles from Condensation of Amidines and α-Haloketones

Li, Bryan, Chiu, Charles K.-F., Hank, Richard F., Murry, Jerry, Roth, Joshua, Tobiassen, Harry

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

3

Process Development and Scale-Up of the Potential Thiazolidinedione Antidiabetic Candidate PNU-91325

Carpenter, Donald E., Imbordino, Rick J., Maloney, Mark T., Moeslein, Jeffery A., Reeder, Michael R., Scott, Allen

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

4

Hydride Reduction of a Lactate Ester: Optimisation and Scale-Up

Donners, M. P. J., Hersmis, M. C., Custers, J. P. A., Meuldijk, J., Vekemans, J. A. J. M., Hulshof, L. A.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

5

Efficient Synthesis of 1-Substituted-5-Hydroxymethylimidazole Derivatives: Clean Oxidative Cleavage of 2-Mercapto Group 1

Chang, Jay Hyok, Lee, Kyu Woong, Nam, Do Hyun, Kim, Won Sup, Shin, Hyunik

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

6

Pharmaceutical Substances: Syntheses, Patents Applications, 4th Edition. (2 Volumes) A. Kleeman, J. Engels, B. Kutscher, and D. Reichert. Georg Thieme Verlag: Stuttgart. 2001. 2521 pp. 599 Euros. ISBN: 3-13-558404-6.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

7

Development of Highly Efficient Resolutions of Racemic Tramadol Using Mandelic Acid

Evans, Graham R., Fernández, Paloma Díaz, Henshilwood, James A., Lloyd, Steve, Nicklin, Chris

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

8

Preparation of 5-(2-Methoxy-4-nitrophenyl)oxazole: A Key Intermediate for the Construction of VX-497

Herr, R. Jason, Fairfax, David J., Meckler, Harold, Wilson, Jeffrey D.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 67 KB

english, 2002

9

A New Route for the Preparation of 5-Hydroxyisophthalic Acid

Gelmont, Mark, Oren, Jakob

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

10

3,4,5-Tri-Dodecyloxybenzoic Acid: Combining Reaction Engineering and Chemistry in the Development of an Attractive Tool To Assist Scaling Up Solid−Liquid Reactions

Custers, J. P. A., Hersmis, M. C., Meuldijk, J., Vekemans, J. A. J. M., Hulshof, L. A.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

11

Cation-Exchange Resin-Catalysed Acylations and Esterifications in Fine Chemical and Perfumery Industries

Yadav, G. D., Rahuman, M. S. M. Mujeebur

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

12

Pilot-Scale Enzymatic Synthesis of Bioactive Oligopeptides in Eutectic-Based Media

Gill, Iqbal, Valivety, Rao

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

13

Preparation of the Key Intermediate in the Synthesis of GV143253A: The Anti-MRSA/E Injectable Trinem

Maragni, Paolo, Mattioli, Mario, Pachera, Roberta, Perboni, Alcide, Tamburini, Bruno

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 321 KB

english, 2002

14

Pilot-Scale Enzymatic Synthesis of 1- O - β - d -Galactopyranosides in Plasticized Glass Phases

Gill, Iqbal, Valivety, Rao

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

15

Evaluation of Raman Spectroscopy for Determining cis and trans Isomers in Partially Hydrogenated Soybean Oil

Johnson, G. L., Machado, R. M., Freidl, K. G., Achenbach, M. L., Clark, P. J., Reidy, S. K.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 121 KB

english, 2002

16

Patent Strategy for Researchers and Research Managers, 2nd Edition By H. Jackson Knight. Wiley & Sons Ltd.: Chichester. 2001. 220 pp. $105. ISBN: 0-471-49260-4.

Schmid, Christopher R.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

17

Process Development of a Dual MMP/TNF Inhibitor (SDZ 242-484)

Koch, Guido, Kottirsch, Georg, Wietfeld, Bernhard, Küsters, Ernst

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

18

The Synthesis of Poly(arylene ether)s in Solution at Pilot-Plant Scale with Control over Molecular Weight and End-Group Composition

Bender, Timothy P., Burt, Richard A., Hamer, Gord K., DeVisser, Christine, Smith, Paul F., Saban, Marko

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 129 KB

english, 2002

19

A Practical Synthesis of the RAR γ Agonist, BMS-270394

Chidambaram, Ramakrishnan, Kant, Joydeep, Zhu, Jason, Lajeunesse, Jean, Sirard, Pierre, Ermann, Peter, Schierling, Peter, Lee, Peter, Kronenthal, David

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

20

Dust Explosion Prevention and Detection: A Practical Guide Edited by John Barton. Institute of Chemical Engineers: Rugby, UK. 2002. 366 pp. £90. ISBN 0-85295-410-7.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

21

Kinetics of Citraconic Anhydride Formation via Condensation of Formaldehyde and Succinates

Shekhawat, Dushyant, Nagarajan, Kirthivasan, Jackson, James E., Miller, Dennis J.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

22

Scale-up in Chemical Engineering By Marko Zlokarnik. Wiley−VCH: Verlag, Germany. 2002. 219 pp. 109 euro. ISBN 3-527-30266-2.

am Ende, David J.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

23

Kinetics and Products Distribution of Selective Catalytic Hydration of Ethylene- and Propylene Oxides in Concentrated Aqueous Solutions

Kozlovsky, I. A., Kozlovsky, R. A., Koustov, A. V., Makarov, M. G., Suchkov, J. P., Shvets, V. F.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

24

Development of a Practical, Safe, and High-Yielding Process for the Preparation of Enantiomerically Pure trans -Cyclopropane Carboxylic Acid

Singh, Ambarish K., Rao, Meena N., Simpson, James H., Li, Wen-Sen, Thornton, John E., Kuehner, Daniel E., Kacsur, David J.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

25

Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, 4th Edition R. P. Pohanish. Noyes/William Andrew Publishing: Norwich, New York. 2002. 2608 pp. $495. ISBN: 0-8155-1459-X.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

26

The Effect of 1- and 2-(1-Hydroperoxy-1-methylethyl)naphthalenes on the Liquid-Phase Oxidation of Alkylaromatic Hydrocarbons

Zawadiak, Jan, Stec, Zbigniew, Orlinska, Beata

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

27

Some Items of Interest to Process R&D Chemists and Engineers

Laird, Trevor, Hermitage, Stephen A., Tilstam, Ulf

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

28

Streamlining Process R&D Using Multidimensional Analytical Technology

McConnell, J. Russell, Barton, Kathy P., LaPack, Mark A., DesJardin, Mike A.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 123 KB

english, 2002

29

New Oxidation of β-Hydroxy α-Methyl Ketones: A Convenient Synthesis of 3-Methylalkane-2,4-diones

Yuasa, Yoshifumi, Kato, Yasushi

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 53 KB

english, 2002

30

Web Submissions and First 2003 Special Feature

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 16 KB

english, 2002

31

An Expedient Synthesis of 6α-Fluoroursodeoxycholic Acid

Königsberger, Kurt, Chen, Guang-Pei, Vivelo, James, Lee, George, Fitt, John, McKenna, Joseph, Jenson, Todd, Prasad, Kapa, Repič, Oljan

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 86 KB

english, 2002

32

Principles and Applications of Asymmetric Synthesis G.-Q. Lin, Y.-M. Li, and A. S. C. Chan. Wiley−Interscience: New York. 2001. 532 pp. £70.50. ISBN: 0-471040027-0.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002