Volume 13; Issue 4

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AAPS PharmSciTech
Volume 13; Issue 4

AAPS PharmSciTech

Volume 13; Issue 4

1

Application of Fourier Transform Near-Infrared Spectroscopy Combined with High-Performance Liquid Chromatography in Rapid and Simultaneous Determination of Essential Components in Crude Radix Scrophulariae

Xiaomeng Li, Dansi Fang, Xiaodong Cong, Gang Cao, Hao Cai, Baochang Cai

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

2

Preparation and Evaluation of Sustained-Release Matrix Tablets Based on Metoprolol and an Acrylic Carrier Using Injection Moulding

T. Quinten, G. P. Andrews, T. De Beer, L. Saerens, W. Bouquet, D. S. Jones, P. Hornsby, J. P. Remon, C. Vervaet

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 593 KB

english, 2012

3

Prediction of Drug Solubility in Lipid Mixtures from the Individual Ingredients

Mark Sacchetti, Elham Nejati

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 310 KB

english, 2012

4

Structure Relationship of Cationic Lipids on Gene Transfection Mediated by Cationic Liposomes

Orapan Paecharoenchai, Nattisa Niyomtham, Auayporn Apirakaramwong, Tanasait Ngawhirunpat, Theerasak Rojanarata, Boon-ek Yingyongnarongkul, Praneet Opanasopit

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

5

Comparative Studies on Chitosan and Polylactic-co-glycolic Acid Incorporated Nanoparticles of Low Molecular Weight Heparin

Tianzhi Yang, Divine Nyiawung, Alexandra Silber, Jiukuan Hao, Leanne Lai, Shuhua Bai

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

6

Enhanced Antiproliferative Activity of the New Anticancer Candidate LPSF/AC04 in Cyclodextrin Inclusion Complexes Encapsulated into Liposomes

Elisângela A. M. Mendonça, Mariane C. B. Lira, Marcelo M. Rabello, Isabella M. F. Cavalcanti, Suely L. Galdino, Ivan R. Pitta, Maria do Carmo A. Lima, Maira G. R. Pitta, Marcelo Z. Hernandes, Nereide

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 765 KB

english, 2012

7

Development of Amphotericin B-Loaded Cubosomes Through the SolEmuls Technology for Enhancing the Oral Bioavailability

Zhiwen Yang, Yinhe Tan, Meiwan Chen, Linghui Dian, Ziyun Shan, Xinsheng Peng, Chuanbin Wu

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

8

Enhanced Dissolution and Stability of Lansoprazole by Cyclodextrin Inclusion Complexation: Preparation, Characterization, and Molecular Modeling

Yi Lu, Tao Guo, Jianping Qi, Jiwen Zhang, Wei Wu

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 505 KB

english, 2012

9

Eudragit-Based Nanosuspension of Poorly Water-Soluble Drug: Formulation andIn Vitro–In VivoEvaluation

Sarita Kumari Yadav, Shivani Mishra, Brahmeshwar Mishra

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 771 KB

english, 2012

10

“Development and Evaluation of Sodium Alginate–Polyacrylamide Graft–Co-polymer-Based Stomach Targeted Hydrogels of Famotidine”

Rahul Tripathi, Brahmeshwar Mishra

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 698 KB

english, 2012

11

Improved Bioavailability of a Water-Insoluble Drug by Inhalation of Drug-Containing Maltosyl-β-Cyclodextrin Microspheres Using a Four-Fluid Nozzle Spray Drier

Tetsuya Ozeki, Yoshihito Kano, Norimitsu Takahashi, Tatsuaki Tagami, Hiroaki Okada

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

12

Microemulsion-Based Oxyresveratrol for Topical Treatment of Herpes Simplex Virus (HSV) Infection: Physicochemical Properties and Efficacy in Cutaneous HSV-1 Infection in Mice

Pattaraporn Sasivimolphan, Vimolmas Lipipun, Garnpimol Ritthidej, Khanidtha Chitphet, Yoshihiro Yoshida, Tohru Daikoku, Boonchoo Sritularak, Kittisak Likhitwitayawuid, Pornpen Pramyothin, Masao Hattor

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 280 KB

english, 2012

13

Matrix Tablets: The Effect of Hydroxypropyl Methylcellulose/Anhydrous Dibasic Calcium Phosphate Ratio on the Release Rate of a Water-Soluble Drug Through the Gastrointestinal Tract I.In VitroTests

Pseidy L. Mamani, Roberto Ruiz-Caro, María D. Veiga

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 390 KB

english, 2012

14

The Influence of the API Properties on the ODTs Manufacturing from Co-processed Excipient Systems

Anna Krupa, Renata Jachowicz, Zbigniew Pędzich, Krystyna Wodnicka

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 705 KB

english, 2012

15

Characterisation of Ilomastat for Prolonged Ocular Drug Release

Gary Parkinson, Simon Gaisford, Qian Ru, Alastair Lockwood, Ashkan Khalili, Rose Sheridan, Peng T. Khaw, Steve Brocchini, Hala M. Fadda

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 640 KB

english, 2012

16

Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology

Noorullah Naqvi Mohammed, Soumyajit Majumdar, Abhilasha Singh, Weibin Deng, Narasimha S. Murthy, Elanor Pinto, Divya Tewari, Thomas Durig, Michael A. Repka

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 841 KB

english, 2012

17

Functional Assessment of Four Types of Disintegrants and their Effect on the Spironolactone Release Properties

John Rojas, Santiago Guisao, Vanesa Ruge

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

18

Quality by Design Approach: Application of Artificial Intelligence Techniques of Tablets Manufactured by Direct Compression

Buket Aksu, Anant Paradkar, Marcel de Matas, Özgen Özer, Tamer Güneri, Peter York

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 246 KB

english, 2012

19

Development and Evaluation of anIn VitroVaginal Model for Assessment of Drug’s Biopharmaceutical Properties: Curcumin

Katja Berginc, Nataša Škalko-Basnet, Purusotam Basnet, Albin Kristl

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

20

Novel pH- and Temperature-Responsive Blend Hydrogel Microspheres of Sodium Alginate and PNIPAAm-g-GG for Controlled Release of Isoniazid

Praveen B. Kajjari, Lata S. Manjeshwar, Tejraj M. Aminabhavi

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

21

Understanding the Oral Mucosal Absorption and Resulting Clinical Pharmacokinetics of Asenapine

Jeremy A. Bartlett, Kees van der Voort Maarschalk

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 280 KB

english, 2012

22

Investigation of Effects of Terpene Skin Penetration Enhancers on Stability and Biological Activity of Lysozyme

Rahul M. Varman, Somnath Singh

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

23

Effect of Formulation Conditions on Hypromellose Performance Properties in Films Used for Capsules and Tablet Coatings

Jaime Curtis-Fisk, Paul Sheskey, Karen Balwinski, Karen Coppens, Carol Mohler, Jin Zhao

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 473 KB

english, 2012

24

Effect of Processing Parameters on the Physical Stability of Silicone Coatings

Nitin Dixit, Kevin M. Maloney, Devendra S. Kalonia

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 151 KB

english, 2012

25

Quality by Design I: Application of Failure Mode Effect Analysis (FMEA) and Plackett–Burman Design of Experiments in the Identification of “Main Factors” in the Formulation and Process Design Space for Roller-Compacted Ciprofloxacin Hydrochloride Immediate-Release Tablets

Raafat Fahmy, Ravikanth Kona, Ramesh Dandu, Walter Xie, Gregg Claycamp, Stephen W. Hoag

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 565 KB

english, 2012

26

Evaluation of the Performance Characteristics of Bilayer Tablets: Part I. Impact of Material Properties and Process Parameters on the Strength of Bilayer Tablets

Niranjan Kottala, Admassu Abebe, Omar Sprockel, James Bergum, Faranak Nikfar, Alberto M. Cuitiño

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 307 KB

english, 2012

27

Evaluation of the Performance Characteristics of Bilayer Tablets: Part II. Impact of Environmental Conditions on the Strength of Bilayer Tablets

Niranjan Kottala, Admassu Abebe, Omar Sprockel, James Bergum, Faranak Nikfar, Alberto M. Cuitiño

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 535 KB

english, 2012

28

Product Development Studies on Surface-Adsorbed Nanoemulsion of Olmesartan Medoxomil as a Capsular Dosage Form

Sumita Singh, Kamla Pathak, Vikas Bali

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 399 KB

english, 2012

29

A Drug-in-Adhesive Matrix Based on Thermoplastic Elastomer: Evaluation of Percutaneous Absorption, Adhesion, and Skin Irritation

ChengXiao Wang, Ran Liu, XiuZhen Tang, Wei Han

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 371 KB

english, 2012

30

The Effects of Supercritical Carbon Dioxide Processing on Progesterone Dispersion Systems: a Multivariate Study

James R. Falconer, Jingyuan Wen, Sara Zargar‐Shoshtari, John J. Chen, Farid Mohammed, Judy Chan, Raid G. Alany

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 354 KB

english, 2012

31

Miniaturized Transfer Models to Predict the Precipitation of Poorly Soluble Weak Bases upon Entry into the Small Intestine

Sandra Klein, Norma L. Buchanan, Charles M. Buchanan

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

32

A Feasibility Study on Pellet Coating Using a High-Speed Quasi-continuous Coater

Christine Cahyadi, Jackson Jie Sheng Koh, Zhi Hui Loh, Lai Wah Chan, Paul Wan Sia Heng

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

33

The Influence of Surfactant HLB and Oil/Surfactant Ratio on the Formation and Properties of Self-emulsifying Pellets and Microemulsion Reconstitution

Irini Matsaridou, Panagiotis Barmpalexis, Andrea Salis, Ioannis Nikolakakis

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 459 KB

english, 2012

34

Development of a Continuous Dissolution/Absorption System—a Technical Note

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 378 KB

english, 2012

35

The Investigation on Polyion Complex Micelles Composed of Diammonium Glycyrrhizinate/Poly(Ethylene Glycol)–Glycidyltrimethylammonium Chloride-Grafted Polyasparthydrazide

Hong Huo, Yikun Gao, Tianyi Wang, Haitao Jiang, Siling Wang, Tongying Jiang

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 270 KB

english, 2012

36

The Use of Artificial Neural Networks for Optimizing Polydispersity Index (PDI) in Nanoprecipitation Process of Acetaminophen in Microfluidic Devices

Mahdi Aghajani, Ahmad Reza Shahverdi, Amir Amani

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

37

Nanocrystallization by Evaporative Antisolvent Technique for Solubility and Bioavailability Enhancement of Telmisartan

Amrita Bajaj, Monica R. P. Rao, Amol Pardeshi, Dhanesh Sali

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 440 KB

english, 2012

38

Effects of Processing on the Release Profiles of Matrix Systems Containing 5-Aminosalicylic Acid

Anita Korbely, András Kelemen, Péter Kása Jr, Klára Pintye-Hódi

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 488 KB

english, 2012

39

The Improvement of the Anticancer Effect of a Novel Compound Benzoic Acid, 2-Hydroxy-, 2-d-ribofuranosylhydrazide (BHR) Loaded in Solid Lipid Nanoparticles

Mei Wang, Lili Qin, Kun Li, Rongrong Zhu, Wenrui Wang, Shilong Wang

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 377 KB

english, 2012

40

Preparation and Characterization of Stable pH-Sensitive Vesicles Composed of α-Tocopherol Hemisuccinate

Huan Xu, Yi-Hui Deng, Kai-Qian Wang, Da-Wei Chen

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 490 KB

english, 2012

41

Investigating the Parameters Affecting the Stability of Superparamagnetic Iron Oxide-Loaded Nanoemulsion Using Artificial Neural Networks

Gholamreza Ahmadi Lakalayeh, Reza Faridi-Majidi, Reza Saber, Alireza Partoazar, Shahram Ejtemaei Mehr, Amir Amani

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

42

Development, Optimization, and Characterization of Solid Self-Nanoemulsifying Drug Delivery Systems of Valsartan Using Porous Carriers

Sarwar Beg, Suryakanta Swain, Harendra Pratap Singh, Ch Niranjan Patra, ME Bhanoji Rao

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 866 KB

english, 2012

43

Formation of Itraconazole–Succinic Acid Cocrystals by Gas Antisolvent Cocrystallization

Courtney A. Ober, Ram B. Gupta

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 548 KB

english, 2012

44

Solid Dispersion of Ursolic Acid in Gelucire 50/13: a Strategy to Enhance Drug Release and Trypanocidal Activity

Josimar de Oliveira Eloy, Juliana Saraiva, Sergio de Albuquerque, Juliana Maldonado Marchetti

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

45

Electric Field-Controlled Benzoic Acid and Sulphanilamide Delivery from Poly(Vinyl Alcohol) Hydrogel

Jarinya Sittiwong, Sumonman Niamlang, Nophawan Paradee, Anuvat Sirivat

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 478 KB

english, 2012

46

Osmotically Regulated Floating Asymmetric Membrane Capsule for Controlled Site-Specific Delivery of Ranitidine Hydrochloride: Optimization by Central Composite Design

Manvendra S. Chauhan, Anil Kumar, Kamla Pathak

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

47

Formulation of Niosomal Gel for Enhanced Transdermal Lopinavir Delivery and Its Comparative Evaluation with Ethosomal Gel

Ketul K. Patel, Praveen Kumar, Hetal P. Thakkar

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 630 KB

english, 2012

48

Chlorhexidine Salt-Loaded Polyurethane Orthodontic Chains:In VitroRelease and Antibacterial Activity Studies

Karine Padois, Valérie Bertholle, Fabrice Pirot, Truc Thanh Ngoc Hyunh, Alessandra Rossi, Paolo Colombo, Françoise Falson, Fabio Sonvico

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

49

Characterization andIn VitroDrug Release Studies of a Natural PolysaccharideTerminalia catappaGum (Badam Gum)

Venkata Srikanth Meka, Sreenivasa Rao Nali, Ambedkar Sunil Songa, Venkata Ramana Murthy Kolapalli

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 781 KB

english, 2012

50

Accelerated Polymer Biodegradation of Risperidone Poly(d,l-Lactide-Co-Glycolide) Microspheres

Francesca Selmin, Paolo Blasi, Patrick P. DeLuca

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 578 KB

english, 2012

51

Using USP I and USP IV for Discriminating Dissolution Rates of Nano- and Microparticle-Loaded Pharmaceutical Strip-Films

Lucas Sievens-Figueroa, Natasha Pandya, Anagha Bhakay, Golshid Keyvan, Bozena Michniak-Kohn, Ecevit Bilgili, Rajesh N. Davé

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 545 KB

english, 2012

52

Effect of Processing Route on the Surface Properties of Amorphous Indomethacin Measured by Inverse Gas Chromatography

D. J. Burnett, J. Khoo, M. Naderi, J. Y. Y. Heng, G. D. Wang, F. Thielmann

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 315 KB

english, 2012

53

Development of Bilayer Floating Tablet of Amoxicillin andAloe veraGel Powder for Treatment of Gastric Ulcers

Arati N. Ranade, Sonali S. Wankhede, Nisharani S. Ranpise, Mayur S. Mundada

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012