Volume 21; Issue 3

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AAPS PharmSciTech
Volume 21; Issue 3

AAPS PharmSciTech

Volume 21; Issue 3

1

Poly(L-Glutamic Acid)-Based Brush Copolymers: Fabrication, Self-assembly, and Evaluation as Efficient Nanocarriers for Cationic Protein Drug Delivery

Li, Xin, Lu, Chao, Xia, Wenquan, Quan, Guilan, Huang, Ying, Bai, Xuequn, Yu, Feiyuan, Xu, Qian, Qin, Wanbing, Liu, Daojun, Pan, Xin

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 2.25 MB

english, 2020

2

Stimuli Responsive In Situ Gelling Systems Loaded with PLGA Nanoparticles of Moxifloxacin Hydrochloride for Effective Treatment of Periodontitis

Beg, Sarwar, Dhiman, Shashi, Sharma, Teenu, Jain, Ashish, Sharma, Rakesh Kumar, Jain, Atul, Singh, Bhupinder

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 3.88 MB

english, 2020

3

Bromocriptine Nanoemulsion-Loaded Transdermal Gel: Optimization Using Factorial Design, In Vitro and In Vivo Evaluation

Sita V G,, Vavia, Pradeep

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 1.58 MB

2020

4

Anti-angiogenesis by dual action of R5K peptide conjugated itraconazole nanoparticles

Chittasupho, Chuda, Kengtrong, Kantalada, Chalermnithiwong, Supawan, Sarisuta, Narong

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 12.68 MB

2020

5

Cardioprotective Efficacy of Silymarin Liquisolid in Isoproterenol Prompted Myocardial Infarction in Rats

Sheta, Nermin M., Elfeky, Yasmin A., Boshra, Sylvia A.

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 2.28 MB

2020

6

Study of Top-down and Bottom-up Approaches by Using Design of Experiment (DoE) to Produce Meloxicam Nanocrystal Capsules

Liu, Tao, Yu, Xinxin, Yin, Haipeng

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 4.35 MB

2020

7

Preparation and Characterization of PLGAâPEGâPLGA Nanoparticles Containing Salidroside and Tamoxifen for Breast Cancer Therapy

Yu, Xuan, Sun, Lili, Tan, Lejun, Wang, Meng, Ren, Xiaoliang, Pi, Jiaxin, Jiang, Miaomiao, Li, Nan

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.97 MB

english, 2020

8

Aprepitant Intravenous Emulsion Based on Ion Pairing/Phospholipid Complex for Improving Physical and Chemical Stability During Thermal Sterilization

Zhang, Xinyu, Wei, Ying, Cao, Zhijun, Xu, Ying, Lu, Cong, Zhao, Meiqi, Gou, Jingxin, Yin, Tian, Zhang, Yu, He, Haibing, Wang, Yanjiao, Tang, Xing

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.55 MB

english, 2020

9

Transdermal Administration of Ibuprofen-Loaded Gel: Preparation, Pharmacokinetic Profile, and Tissue Distribution

Xia, Meng-qiu, Tian, Chun-ling, Liu, Liu, Hu, Rong-feng, Gui, Shuang-ying, Chu, Xiao-qin

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 528 KB

english, 2020

10

Effect of a Solid Lipid Nanoparticle Formulation on the Bioavailability of 4-(N)-Docosahexaenoyl 2â², 2â²-Difluorodeoxycytidine After Oral Administration

Valdes, Solange A., Alzhrani, Riyad F., Lansakara-P, Dharmika S. P., Cui, Zhengrong

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 3.03 MB

2020

11

Effect of Formulation Variables and Gamma Sterilization on Transcorneal Permeation and Stability of Proniosomal Gels as Ocular Platforms for Antiglaucomal Drug

Sayed, Sinar, Abdelmoteleb, Mostafa, Amin, Maha M., Khowessah, Omnia M.

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.18 MB

english, 2020

12

Fabrication of Fine Puerarin Nanocrystals by BoxâBehnken Design to Enhance Intestinal Absorption

Cheng, Meng, Yuan, Fangying, Liu, Jiali, Liu, Wan, Feng, Jianfang, Jin, Yi, Tu, Liangxing

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 5.08 MB

2020

13

Comparative Bioavailability of Oral Granule Formulations of the HIV Antiretroviral Drugs Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate

Yee, Ka Lai, DiBenedetto, Adrienne, Fan, Li, Khalilieh, Sauzanne, Triantafyllou, Ilias, Vallee, Marie-Helene, Fackler, Paul, Stoch, S. Aubrey, Iwamoto, Marian

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 362 KB

2020

14

Exploring the Potential of Hydrophilic Matrix Combined with Insoluble Film Coating: Preparation and Evaluation of Ambroxol Hydrochloride Extended Release Tablets

Hu, Manyu, Zhu, Zhuangzhi, Wu, Yubo, Meng, Qingqing, Luo, Jing, Wang, Hao

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.38 MB

english, 2020

15

Correction to: Development of Methotrexate and Minocycline Loaded Nanoparticles for the Effective Treatment of Rheumatoid Arthritis

Janakiraman, Kumar, Krishnaswami, Venkateshwaran, Sethuraman, Vaidevi, Natesan, Subramanian, Rajendran, Vijaya, Kandasamy, Ruckmani

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 162 KB

english, 2020

16

Protecting the Normal Physiological Functions of Articular and Periarticular Structures by Aurum Nanoparticle-Based Formulations: an Up-to-Date Insight

Famta, Paras, Famta, Mani, Kaur, Jaskiran, Khursheed, Rubiya, Kaur, Amanjot, Khatik, Gopal L., Pawde, Datta Maroti, Rahman, Syed Nazrin Ruhina, Shunmugaperumal, Tamilvanan

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.99 MB

english, 2020

17

Structure-Properties Relationship in the Evaluation of Alginic Acid Functionality for Tableting

Benabbas, Rihab, Sanchez-Ballester, Noelia M., Bataille, Bernard, Leclercq, Laurent, Sharkawi, Tahmer, Soulairol, Ian

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 876 KB

english, 2020

18

Predicting Density of Amorphous Solid Materials Using Molecular Dynamics Simulation

Bookwala, Mustafa, DeBoyace, Kevin, Buckner, Ira S., Wildfong, Peter L. D.

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 1.94 MB

2020

19

Optimization and Evaluation of the Thermosensitive In Situ and Adhesive Gel for Rectal Delivery of Budesonide

Chen, Lin, Han, Xue, Xu, Xiaohong, Zhang, Quan, Zeng, Yingchun, Su, Qing, Liu, Yujie, Sheng, Yanmei, Xie, Xingliang

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 1.99 MB

2020

20

Development of Abuse-Deterrent Formulations Using Sucrose Acetate Isobutyrate

Barakh Ali, Sogra F., Dharani, Sathish, Afrooz, Hamideh, Mohamed, Eman M., Cook, Phillip, Khan, Mansoor A., Rahman, Ziyaur

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 5.97 MB

2020

21

Simulation of the Pharmacokinetics of Oseltamivir and Its Active Metabolite in Normal Populations and Patients with Hepatic Cirrhosis Using Physiologically Based Pharmacokinetic Modeling

Chen, Yong, Ke, Meng, Xu, Jianwen, Lin, Cuihong

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 1.39 MB

2020

22

Food Protein-Based Nanodelivery Systems for Hydrophobic and Poorly Soluble Compounds

Maviah, Mily Bazezy Joelle, Farooq, Muhammad Asim, Mavlyanova, Rukhshona, Veroniaina, Hanitrarimalala, Filli, Mensura Sied, Aquib, Md, Kesse, Samuel, Boakye-Yiadom, Kofi Oti, Wang, Bo

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 585 KB

2020

23

Formulation and Clinical Evaluation of Sodium Benzoate Oral Solution for the Treatment of Urea Cycle Disorders in Pediatric Patients

Maines, E., Urru, S. A. M., Burri, E., Piccoli, G., Pedrolli, A., Pasqualini, A., Burlina, A. L., Temporin, G.

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 554 KB

2020

24

Understanding the Oral Absorption of Irbesartan Using Biorelevant Dissolution Testing and PBPK Modeling

Kaur, Navpreet, Thakur, Poonam Singh, Shete, Ganesh, Gangwal, Rahul, Sangamwar, Abhay T., Bansal, Arvind Kumar

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 2.21 MB

2020

25

Simulation of Unit Operations in Formulation Development of Tablets Using Computational Fluid Dynamics

Hemamanjushree, S, Tippavajhala, Vamshi Krishna

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.41 MB

english, 2020

26

Effects of Diluents on Physical and Chemical Stability of Phenytoin and Phenytoin Sodium

Rahman, Ziyaur, Dharani, Sathish, Barakh Ali, Sogra F., Nutan, Mohammad T. H., Khan, Mansoor A.

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 13.41 MB

english, 2020

27

Liquisolid System and Liqui-Mass System Are Not the Same

Lam, Matthew, Ghafourian, Taravat, Nokhodchi, Ali

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 202 KB

english, 2020

28

The Opposed Effects of Polyvinylpyrrolidone K30 on Dissolution and Precipitation for Indomethacin Supersaturating Drug Delivery Systems

Wang, Wenxi, Li, Mengting, Yang, Qingliang, Liu, Qing, Ye, Mengdie, Yang, Gensheng

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.53 MB

english, 2020

29

Effects of Uncleavable and Cleavable PEG-Lipids with Different Molecular Weights on Accelerated Blood Clearance of PEGylated Emulsions in Beagle Dogs

Jiao, Jiao, Luo, Xiang, Wang, Chunling, Jiao, Xiaoqin, Liu, Mengyang, Liu, Xinrong, Wei, Liting, Deng, Yihui, Song, Yanzhi

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.42 MB

english, 2020

30

Lyophilisation Improves Bioactivity and Stability of Insulin-Loaded Polymeric-Oligonucleotide Nanoparticles for Diabetes Treatment

Wong, Chun Y., Al-Salami, Hani, Dass, Crispin R.

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 1.74 MB

english, 2020

31

Transdermal Delivery of the Free Base of 3-Fluoroamphetamine: In Vitro Skin Permeation and Irritation Potential

Jiang, Ying, Murnane, Kevin S., Blough, Bruce E., Banga, Ajay K.

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 789 KB

english, 2020

32

Combined Therapy for Alzheimerâs Disease: Tacrine and PAMAM Dendrimers Co-Administration Reduces the Side Effects of the Drug without Modifying its Activity

IgartÃºa, Daniela E., Martinez, Carolina S., del V. Alonso, Silvia, Prieto, M. Jimena

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 3.65 MB

english, 2020

33

A Novel Prototype Device for Microencapsulation of Benznidazole: In Vitro/In Vivo Studies

Barrera, MarÃa G., Tejada, Guillermo, Leonardi, DarÃo, Lamas, MarÃa C., SalomÃ³n, Claudio J.

Journal:

AAPS PharmSciTech

Year:

2020

Language:

english

File:

PDF, 540 KB

english, 2020

34

Data-Driven Modeling of the Bicalutamide Dissolution from Powder Systems

Mendyk, Aleksander, PacÅawski, Adam, Szafraniec-SzczÄsny, Joanna, Antosik, Agata, JamrÃ³z, Witold, Paluch, Marian, Jachowicz, Renata

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 478 KB

2020

35

Novel Enhanced Therapeutic Efficacy of Dapoxetine HCl by Nano-Vesicle Transdermal Gel for Treatment of Carrageenan-Induced Rat Paw Edema

Salem, Heba F., Nafady, Mohamed M., Kharshoum, Rasha M., Abd el-Ghafar, Omnia A., Farouk, Hanan O.

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 629 KB

2020

36

Development of Nanocrystal Ziprasidone Orally Disintegrating Tablets: Optimization by Using Design of Experiment and In Vitro Evaluation

Tashan, Emine, Karakucuk, Alptug, Celebi, Nevin

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 649 KB

2020

37

Quantification of Monomer Units in Insoluble Polymeric Active Pharmaceutical Ingredients Using Solid-State NMR Spectroscopy I: Patiromer

Jarrells, Travis W., Zhang, Deyi, Li, Shaohua, Munson, Eric J.

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 2.42 MB

2020

38

Determination of Rate and Extent of Scopolamine Release from Transderm ScÅpÂ® Transdermal Drug Delivery Systems in Healthy Human Adults

Swaminathan, Suresh Kumar, Strasinger, Caroline, Kelchen, Megan, Carr, Jamie, Ye, Wei, Wokovich, Anna, Ghosh, Priyanka, Rajagopal, Srinivasan, Ueda, Kenichi, Fisher, James, Kandimalla, Karunya K., Bro

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 413 KB

2020

39

The Route to Palatable Fecal Microbiota Transplantation

Journal:

AAPS PharmSciTech

Year:

2020

File:

PDF, 1009 KB

2020

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