Volume 11; Issue 2

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Pharmaceutical Research
Volume 11; Issue 2

Pharmaceutical Research

Volume 11; Issue 2

1

The Physicochemical Properties, Plasma Enzymatic Hydrolysis, and Nasal Absorption of Acyclovir and Its 2′-Ester Prodrugs

Zezhi Shao, Gee-Bae Park, Ramesh Krishnamoorthy, Ashim K. Mitra

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.03 MB

1994

2

Identification of the Pathway of lontophoretic Drug Delivery: Light and Ultrastructural Studies Using Mercuric Chloride in Pigs

Nancy A. Monteiro-Riviere, Alfred O. Inman, Jim E. Riviere

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 3.42 MB

1994

3

Intestinal Absorption of (–)-Carbovir in the Rat

Inmaculada Soria, Cheryl L. Zimmerman

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 921 KB

1994

4

Effect of Formulation Additives upon the Intranasal Bioavailability of a Peptide Drug: Tetracosactide (ACTH1−24)

Patrick Wüthrich, Myriam Martenet, Pierre Buri

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 848 KB

1994

5

Effect of Some Penetration Enhancers on Epithelial Membrane Lipid Domains: Evidence from Fluorescence Spectroscopy Studies

T. Marjukka Turunen, Arto Urtti, Petteri Paronen, Kenneth L. Audus, J. Howard Rytting

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.08 MB

1994

6

Improved Dose Linearity of Cyclosporine Pharmacokinetics from a Microemulsion Formulation

Edgar A. Mueller, John M. Kovarik, Johannes B. van Bree, Wolfgang Tetzloff, Joachim Grevel, Klaus Kutz

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 619 KB

1994

7

Efflux of Zidovudine and 2′,3′-Dideoxyinosine Out of the Cerebrospinal Fluid When Administered Alone and in Combination toMacaca nemestrina

Tove Tuntland, Rashid J. Ravasco, Sayed Al-Habet, Jashvant D. Unadkat

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.12 MB

1994

8

In Vitroandin VivoTransport of Zidovudine (AZT) Across the Blood–Brain Barrier and the Effect of Transport Inhibitors

Rosalinde Masereeuw, Ulrich Jaehde, Mariska W. E. Langemeijer, Albertus G. de Boer, Douwe D. Breimer

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.31 MB

1994

9

Entrapment of Proteins in Poly(L-Lactide) Microspheres Using Reversed Micelle Solvent Evaporation

Yoshiki Hayashi, Sumie Yoshioka, Yukio Aso, Alain Li Wan Po, Tadao Terao

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 562 KB

1994

10

Evaluation of Retinoids as Therapeutic Agents in Dermatology

Anita H. Lewin, Mary E. Bos, F. Christopher Zusi, Xina Nair, Gary Whiting, Pamela Bouquin, Geraldine Tetrault, F. Ivy Carroll

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.36 MB

1994

11

Degradation of the Antiarthritic Prodrug, 3-Carboxy-5-methyl-N-[4-(trifluoromethoxy)phenyl]-4-isoxazolecarboxamide, in Aqueous Solution

Michael Brandl, James A. Kennedy

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 446 KB

1994

12

A Mixed Micellar Formulation Suitable for the Parenteral Administration of Taxol

Hayat Alkan-Onyuksel, Suganthi Ramakrishnan, Hee-Byung Chai, John M. Pezzuto

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.13 MB

1994

13

Solute Absorption from the Airways of the Isolated Rat Lung. IV. Mechanisms of Absorption of Fluorophore-Labeled Poly-α,β-[N(2-Hydroxyethyl)-DL-Aspartamide]

Peter R. Byron, Zhuang Sun, Hirokazu Katayama, Frantisek Rypacek

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 918 KB

1994

14

Formulation andin Vitro–in VivoEvaluation of Buccoadhesive Morphine Sulfate Tablets

Şule Anlar, Yilmaz Çapan, Olgun Güven, Ahmet Göğüş, Turgay Dalkara, Atillâ Hincal

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1022 KB

1994

15

Bile Salt–Fatty Acid Mixed Micelles as Nasal Absorption Promoters. III. Effects on Nasal Transport and Enzymatic Degradation of Acyclovir Prodrugs

Zezhi Shao, Ashim K. Mitra

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.40 MB

1994

16

Comparative Molecular Field Analysis Combined with Physicochemical Parameters for Prediction of Polydimethylsiloxane Membrane Flux in Isopropanol

Rong Liu, Lloyd E. Matheson

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.82 MB

1994

17

The Controlled Release of Prednisolone Using Alginate Gel

Shinya Sugawara, Teruko Imai, Masaki Otagiri

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 943 KB

1994

18

Determination of Transport Rates for Arginine and Acetaminophen in Rabbit Intestinal Tissuesin Vitro

Peter W. Swaan, Gary J. Marks, Frederick M. Ryan, Philip L. Smith

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 885 KB

1994

19

Effect of the H2-Receptor Antagonist Cimetidine, on the Pharmacokinetics and Pharmacodynamics of the H1-Receptor Antagonists Hydroxyzine and Cetirizine in Rabbits

Xueyu Chen, F. Estelle R. Simons, Keith J. Simons

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.09 MB

1994

20

In Vivoandin VitroBlood–Brain Barrier Transport of 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors

Akira Saheki, Tetsuya Terasaki, Ikumi Tamai, Akira Tsuji

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.10 MB

1994

21

Phenobarbital Removal Characteristics of Three Brands of Activated Charcoals: A System Analysis Approach

Nishit B. Modi, Peter Veng-Pedersen, Dale Eric Wurster, Mary J. Berg, Dorothy D. Schottelius

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.10 MB

1994

22

Fluorometric Study of the Molecular States of 2,5-Diphenyloxazole in Ground Mixtures with γ-Cyclodextrin

Keiji Yamamoto, Toshio Oguchi, Etsuo Yonemochi, Yoshisuke Matsumura, Yoshinobu Nakai

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 853 KB

1994

23

In Vivoandin VitroAnalysis of Skin Penetration Enhancement Based on a Two-Layer Diffusion Model with Polar and Nonpolar Routes in the Stratum Corneum

Fumiyoshi Yamashita, Hiroto Bando, Yasuo Koyama, Shuji Kitagawa, Yoshinobu Takakura, Mitsuru Hashida

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.19 MB

1994

24

Lack of Pharmacokinetic Interaction Between Cimetidine and Tirilazad Mesylate

Joseph C. Fleishaker, Laura K. Hulst, Gary R. Peters

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 599 KB

1994

25

Solubility Predictions for Solid Nitriles and Tertiary Amides Based on the Mobile Order Theory

Paul Ruelle, Ulrich W. Kesselring

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 828 KB

1994

26

Further Commentary: Physiological Parameters in Laboratory Animals and Humans

Robert B. Sothern, Scott A. Gruber

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 349 KB

1994

27

Pharmacokinetics and Tissue Distribution of Recombinant Human Transforming Growth Factor Beta1After Topical and Intravenous Administration in Male Rats

Thomas F. Zioncheck, Sharon A. Chen, Louise Richardson, Marina Mora-Worms, Catherine Lucas, Derf Lewis, James D. Green, Joyce Mordenti

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 2.34 MB

1994

28

Colonic Absorption of Insulin-like Growth Factor Iin Vitro

Elizabeth Quadros, Nancy M. Landzert, Sheryl LeRoy, Francis Gasparini, Gregory Worosila

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 976 KB

1994