Volume 11; Issue 6

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Pharmaceutical Research
Volume 11; Issue 6

Pharmaceutical Research

Volume 11; Issue 6

1

Geometric Approach for Zero-Order Release of Drugs Dispersed in an Inert Matrix

Mohsen A. Bayomi

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 512 KB

1994

2

Inhibition of Human CYP3A Catalyzed 1′-Hydroxy Midazolam Formation by Ketoconazole, Nifedipine, Erythromycin, Cimetidine, and Nizatidine

Steven A. Wrighton, Barbara J. Ring

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 661 KB

1994

3

The Role of Intramolecular Nucleophilic Catalysis and the Effects of Self-Association on the Deamidation of Human Insulin at Low pH

Richard T. Darrington, Bradley D. Anderson

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.75 MB

1994

4

Predictions ofin VivoPlasma Concentrations fromin VitroRelease Kinetics: Application to Doxepin Parenteral (I.M.) Suspensions in Lipophilic Vehicles in Dogs

Christina Gido, Peter Langguth, Ernst Mutschler

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.36 MB

1994

5

Pharmacodynamic Models of Nitroglycerin-Induced Hemodynamic Tolerance in Experimental Heart Failure

John Anthony Bauer, Ho-Leung Fung

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.38 MB

1994

6

The Cutoff Time Point of the Partial Area Method for Assessment of Rate of Absorption in Bioequivalence Studies

Panos Macheras, Mira Symillides, Christos Reppas

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 531 KB

1994

7

Oral Bioavailability of the Antiretroviral Agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) from Three Formulations of the Prodrug Bis(pivaloyloxymethyl)-PMEA in Fasted Male Cynomolgus Monkeys

Kenneth C. Cundy, James A. Fishback, Jeng-Pyng Shaw, Min L. Lee, Kenneth F. Soike, Gary C. Visor, William A. Lee

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 905 KB

1994

8

Inhibition of Rat Splenocyte Proliferation with Methylprednisolone:In VivoEffect of Liposomal Formulation

Elena V. Mishina, William J. Jusko

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.25 MB

1994

9

Effect ofStreptococcus pneumoniaeand Influenza A Virus on Middle Ear Antimicrobial Pharmacokinetics in Experimental Otitis Media

Gregg H. Jossart, Daniel M. Canafax, Gary R. Erdmann, Michael J. Lovdahl, Henry Q. Russlie, Steven K. Juhn, G. Scott Giebink

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 809 KB

1994

10

Poly(Alkylcyanoacrylate) Nanocapsules: Physicochemical Characterization and Mechanism of Formation

François Chouinard, Stéphane Buczkowski, Vincent Lenaerts

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.46 MB

1994

11

Mechanical Properties of Dry and Wet Cellulosic and Acrylic Films Prepared from Aqueous Colloidal Polymer Dispersions Used in the Coating of Solid Dosage Forms

Roland Bodmeier, Ornlaksana Paeratakul

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.28 MB

1994

12

Distribution of Brush-Border Membrane Peptidases Along the Rat Intestine

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 784 KB

1994

13

Improvement of the Pulmonary Absorption of (Asu1,7)-Eel Calcitonin by Various Protease Inhibitors in Rats

Takahiro Morita, Akira Yamamoto, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 956 KB

1994

14

Interaction Between Ciprofloxacin and Metal Cations: Its Influence on Physicochemical Characteristics and Antibacterial Activity

Ronald C. Li, David E. Nix, Jerome J. Schentag

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 719 KB

1994

15

Pharmaceutical Applications of Microcalorimetry

Michael J. Koenigbauer

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.29 MB

1994

16

A Regulatory and Industrial Perspective of the Use of Carbon-14 and Tritium Isotopes in Human ADME Studies

Jeremy G. Dain, Jerry M. Collins, William T. Robinson

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 681 KB

1994

17

Mucus Gel Thickness and Turnover in the Gastrointestinal Tract of the Rat: Response to Cholinergic Stimulus and Implication for Mucoadhesion

Abraham Rubinstein, Boaz Tirosh

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.44 MB

1994

18

Percutaneous Absorption of 2′,3′-Dideoxyinosine in Rats

Elora Mukherji, Nancy J. Millenbaugh, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.28 MB

1994

19

Pharmacokinetics and Bioinversion of Ibuprofen Enantiomers in Humans

Haiyung Cheng, J. Douglas Rogers, Joan L. Demetriades, Sherry D. Holland, James R. Seibold, Elizabeth Depuy

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.14 MB

1994

20

Microdialysis: An Alternative forin Vitroandin VivoProtein Binding Studies

Anne Le Quellec, Sylvie Dupin, Ala Eldin Tufenkji, Patrick Genissel, Georges Houin

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 740 KB

1994

21

HPLC Assay for FK 506 and Two Metabolites in Isolated Rat Hepatocytes and Rat Liver Microsomes

Beatrice Y. T. Perotti, Thomayant Prueksaritanont, Leslie Z. Benet

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 690 KB

1994

22

Comparison of Two Otitis Media Models for the Study of Middle Ear Antimicrobial Pharmacokinetics

Daniel M. Canafax, Henry Russlie, Michael J. Lovdahl, Gary R. Erdmann, Chap T. Le, G. Scott Giebink

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 713 KB

1994

23

Chemical Interactions Between Drugs Containing Reactive Amines with Hydrolyzable Insoluble Biopolymers in Aqueous Solutions

Abraham J. Domb, Ludmila Turovsky, Raphael Nudelman

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 694 KB

1994

24

Structural Rheology of a Model Ointment

Lorraine E. Pena, Barbara L. Lee, James F. Stearns

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 2.35 MB

1994

25

Novel Taxol Formulations: Preparation and Characterization of Taxol-Containing Liposomes

Amarnath Sharma, Robert M. Straubinger

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 3.78 MB

1994

26

Chemical Pathways of Peptide Degradation. VII. Solid State Chemical Instability of an Aspartyl Residue in a Model Hexapeptide

Cecilia Oliyai, Jitendra P. Patel, Linda Carr, Ronald T. Borchardt

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.31 MB

1994

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