Volume 12; Issue 3

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Pharmaceutical Research
Volume 12; Issue 3

Pharmaceutical Research

Volume 12; Issue 3

1

The Description of the Gastrointestinal Transit of Pellets Assessed by Gamma Scintigraphy Using Statistical Moments

Fridrun Podczeck, John Michael Newton, Kay-Hay Yuen

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 653 KB

1995

2

Drug Delivery Studies in Caco-2 Monolayers. Synthesis, Hydrolysis, and Transport of O-Cyclopropane Carboxylic Acid Ester Prodrugs of Various β-Blocking Agents

Lars Hovgaard, Helle Brøndsted, Anders Buur, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.04 MB

1995

3

In Vitroandin VivoEvaluation of Mucoadhesive Microspheres Prepared for the Gastrointestinal Tract Using Polyglycerol Esters of Fatty Acids and a Poly(acrylic acid) Derivative

Yohko Akiyama, Naoki Nagahara, Toshio Kashihara, Shinichiro Hirai, Hajime Toguchi

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 2.08 MB

1995

4

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation ofin VitroDrug Product Dissolution andin VivoBioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah, John R. Crison

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.34 MB

1995

5

Regional Rectal Perfusion: A New in Vivo Approach to Study Rectal Drug Absorption in Man

Hans Lennernäs, Urban Fagerholm, Yngve. Raab, Bengt Gerdin, Roger Hällgren

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.29 MB

1995

6

Pharmacodynamic Analysis of Analgesic Clinical Trials Using Empirical Methods

Chui Yu Liu, Nancy C. Sambol

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.07 MB

1995

7

Stabilization of Human Epidermal Growth Factor (hEGF) in Aqueous Formulation

Kyonghee Son, Changhyuk Kwon

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 587 KB

1995

8

Pharmacodynamic Modeling of Prednisolone Effects on Natural Killer Cell Trafficking

Zhi-Xin Xu, Mi-Jeong Lee, Robert A. Blum, William J. Jusko

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 761 KB

1995

9

The Importance of Structural Factors on the Rate and the Extent of N,O-acyl Migration in Cyclic and Linear Peptides

Reza Oliyai, Teruna J. Siahaan, Valentine J. Stella

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.00 MB

1995

10

Crystal Structure of 2-Debenzoyl, 2-Acetoxy Paclitaxel (Taxol®): Conformation of the Paclitaxel Side-Chain

Qi Gao, Jian-Mei Wei, Shu-Hui Chen

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 896 KB

1995

11

Chemical Pathways of Peptide Degradation. VIII. Oxidation of Methionine in Small Model Peptides by Prooxidant/Transition Metal Ion Systems: Influence of Selective Scavengers for Reactive Oxygen Intermediates

Shihong Li, Christian Schöneich, Ronald T. Borchardt

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.28 MB

1995

12

Transepithelial Transport Properties of Peptidomimetic Thrombin Inhibitors in Monolayers of a Human Intestinal Cell Line (Caco-2) and Their Correlation toin VivoData

Elke Walter, Thomas Kissel, Martin Reers, Gerhard Dickneite, Dieter Hoffmann, Werner Stüber

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.05 MB

1995

13

Tumor Selective Effect of RS-1541 (Palmitoyl-Rhizoxin) in M5076 Sarcoma and Host Tissuesin Vivo

Taro Tokui, Naoyuki Maeda, Chitose Kuroiwa, Kazuhiko Sasagawa, Takashi Inoue, Kenji Kawai, Toshihiko Ikeda, Toru Komai

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 898 KB

1995

14

The Application of Malononitriles as Microviscosity Probes in Pharmaceutical Systems

Sherry L. LaPorte, Abizer Harianawala, Robin H. Bogner

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.05 MB

1995

15

The Effect of Different Concentrations of Mannitol in Solution on Small Intestinal Transit: Implications for Drug Absorption

Dawn A. Adkin, Stanley S. Davis, Robert A. Sparrow, Paul D. Huckle, Anthony J. Phillips, Ian R. Wilding

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 690 KB

1995

16

Neural Network Predicted Peak and Trough Gentamicin Concentrations

Michael E. Brier, Jacek M. Zurada, George R. Aronoff

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.18 MB

1995

17

Analysis of Tissue Distribution of Valproate in Guinea-Pigs: Evidence for Its Capacity-Limited Tissue Distribution

Hsiu-Ying Yu, Yu-Zen Shen

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 680 KB

1995

18

A Compartmental Model for the Ocular Pharmacokinetics of Cyclosporine in Rabbits

Clifford Oh, Bradley A. Saville, Yu-Ling Cheng, David S. Rootman

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 955 KB

1995

19

Second Derivative Infrared Spectroscopy as a Non-Destructive Tool to Assess the Purity and Structural Integrity of Proteins

D. Michael Byler, Rachel M. Wilson, Cynthia S. Randall, Theodore D. Sokoloski

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.03 MB

1995

20

Functional Evaluation of Anchored Skin Equivalent Culturedin Vitro: Percutaneous Absorption Studies and Lipid Analysis

Martine Michel, Lucie Germain, Pierre Maxime Bélanger, François A. Auger

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.04 MB

1995

21

Soft Drugs. XX. Design, Synthesis, and Evaluation of Ultra-Short Acting Beta-Blockers

Hee-Sun Yang, Whei-Mei Wu, Nicholas Bodor

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.33 MB

1995

22

Physicochemical Characterization of Parenteral Lipid Emulsion: Determination of Hamaker Constants and Activation Energy of Coalescence

Tetsuo Yamaguchi, Kaori Nishizaki, Shigeru Itai, Hidefumi Hayashi, Hiroyuki Ohshima

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 902 KB

1995

23

The Influence of Regional Deposition on the Pharmacokinetics of Pulmonary-Delivered Human Growth Hormone in Rabbits

Paul Colthorpe, Stephen J. Fair, Ian J. Smith, David Wyatt, Glyn Taylor

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 745 KB

1995

24

A Non-Ionic Vesicle Lipid Enhances Mastoparan-Stimulated GTPase Activity of Heterotrimeric G-Proteins

Bernd Nürnberg, Ralph Hoppe, Ulrich Rümenapp, Rainer Harhammer, Eberhard Nürnberg

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 830 KB

1995