Volume 16; Issue 8

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Pharmaceutical Research
Volume 16; Issue 8

Pharmaceutical Research

Volume 16; Issue 8

1

Fluorescence Recovery After Photobleaching: A Versatile Tool for Mobility and Interaction Measurements in Pharmaceutical Research

Tom K. L. Meyvis, Stefaan C. De Smedt, Patrick Van Oostveldt, Joseph Demeester

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.81 MB

1999

2

Determination of Air Content in Protein Microspheres

Svein Kvåle, Knut R. Dyrstad, Per C. Sontum, Odd A. Asbjørnsen

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 611 KB

1999

3

News from the National Institute of General Medical Sciences (NIGMS)

Alisa Zapp Machalek

Journal:

Pharmaceutical Research

Year:

1999

Language:

english

File:

PDF, 369 KB

english, 1999

4

Gastropods as an Evaluation Tool for Screening the Irritating Potency of Absorption Enhancers and Drugs

Els Adriaens, JeanPaul Remon

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 948 KB

1999

5

Stool Water Content and Colonic Drug Absorption: Contrasting Effects of Lactulose and Codeine

John M. Hebden, Peter J. Gilchrist, Alan C. Perkins, Clive G. Wilson, Robin C. Spiller

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.02 MB

1999

6

Transcellular and Lipophilic Complex-Enhanced Intestinal Absorption of Human Growth Hormone

Sy-Juen Wu, Joseph R. Robinson

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.36 MB

1999

7

Organic Cation Transport in Rabbit Alveolar Epithelial Cell Monolayers

Jie Shen, Katharina J. Elbert, Fumiyoshi Yamashita, Claus-Michael Lehr, Kwang-Jin Kim, Vincent H. L. Lee

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.89 MB

1999

8

Evaluation of the Pharmacokinetic Features and Tissue Distribution of the Potent Nonnucleoside Inhibitor of HIV-1 Reverse Transcriptase, N-[2-(2-fluorophenethyl)]-N′-[2-(5-bromopyridyl)]-thiourea (HI-240) with an Analytical HPLC Method

Chun-Lin Chen, Fatih M. Uckun

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.11 MB

1999

9

Why Does PEG 400 Co-Encapsulation Improve NGF Stability and Release from PLGA Biodegradable Microspheres?

Jean-Manuel Péan, Franck Boury, Marie-Claire Venier-Julienne, Philippe Menei, Jacques-Emile Proust, Jean-Pierre Benoit

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.19 MB

1999

10

Pharmacokinetics and Tissue Disposition in Monkeys of an Antisense Oligonucleotide Inhibitor of Ha-Ras Encapsulated in Stealth Liposomes

Rosie Z. Yu, Richard S. Geary, Janet M. Leeds, Tanya Watanabe, Jonathon R. Fitchett, John E. Matson, Rahul Mehta, Gregory R. Hardee, Michael V. Templin, Ken Huang, Mary S. Newman, Yoli Quinn, Paul Ust

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.30 MB

1999

11

Impact of Regional Intestinal pH Modulation on Absorption of Peptide Drugs: Oral Absorption Studies of Salmon Calcitonin in Beagle Dogs

Yong-Hee Lee, Barbara A. Perry, Stacy Labruno, HeeSang Lee, William Stern, Lisa M. Falzone, Patrick J. Sinko

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.25 MB

1999

12

Membrane-Interaction QSAR Analysis: Application to the Estimation of Eye Irritation by Organic Compounds

Amit S. Kulkarni, A.J. Hopfinger

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.94 MB

1999

13

Likelihood-Based Diagnostics for Influential Individuals in Non-Linear Mixed Effects Model Selection

Sima Sadray, E.Niclas Jonsson, Mats O. Karlsson

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1019 KB

1999

14

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li, Hans-Peter Elsässer, Thomas Kissel

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.62 MB

1999

15

Chemical Uptake Into Human Stratum Corneum In Vivo from Volatile and Non-Volatile Solvents

Audra L. Stinchcomb, Fabrice Pirot, Gilles D. Touraille, Annette L. Bunge, Richard H. Guy

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 960 KB

1999

16

Controlled DNA Delivery Systems

Dan Luo, Kim Woodrow-Mumford, Nadya Belcheva, W.Mark Saltzman

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.56 MB

1999

17

An Interview with a Distinguished Pharmaceutical Scientist: Sung Wan Kim To whom correspondence should be addressed at Biomedical Polymers Research Building, Room 205, University of Utah, Salt Lake City, Utah 84112.

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 725 KB

1999

18

BOOK REVIEWS

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 977 KB

1999

19

ERRATUM

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 106 KB

1999

20

Synthesis of a Lipophilic Prodrug of 9-(2-Phosphonylmethoxyethyl)adenine (PMEA) and Its Incorporation into a Hepatocyte-Specific Lipidic Carrier

Remco L. A. de Vrueh, Erik T. Rump, Leo A. J. M. Sliedregt, Erik A. L. Biessen, Theo J. C. van Berkel, Martin K. Bijsterbosch

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.44 MB

1999

21

Compaction Properties of Composite Particles Consisting of Lactose with Sodium Alginate Prepared by Spray-Drying

Hirofumi Takeuchi, Takehiko Yasuji, Tomoaki Hino, Hiromitsu Yamamoto, Yoshiaki Kawashima

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.22 MB

1999

22

Role of P-Glycoprotein on the CNS Disposition of Amprenavir (141W94), an HIV Protease Inhibitor

Joseph W. Polli, Jeanne L. Jarrett, Scott D. Studenberg, Joan E. Humphreys, Steven W. Dennis, Kenneth R. Brouwer, Joseph L. Woolley

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.91 MB

1999

23

Pharmacokinetics of Methotrexate in the Extracellular Fluid of Brain C6-Glioma After Intravenous Infusion in Rats

Sylvain Dukic, Tony Heurtaux, Matthieu L. Kaltenbach, Guillaume Hoizey, Aude Lallemand, Bertrand Gourdier, Richard Vistelle

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.81 MB

1999

24

Design of Potent Phosphorothioate Antisense Oligonucleotides Directed to Human Interleukin 10 Gene Product and Their Evaluation of Antisense Activity in U937 Cells

Hidetoshi Arima, Mamiko Takahashi, Yukihiko Aramaki, Takatoshi Sakamoto, Kazuhiro Yuda, Katsuhiko Akiyama, Takeshi Goto, Seishi Tsuchiya

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.53 MB

1999

25

Synthesis and In Vitro Evaluation of Aminoacyloxyalkyl Esters of 2-(6-methoxy-2-naphthyl)propionic Acid as Novel Naproxen Prodrugs for Dermal Drug Delivery

Jarkko Rautio, Tapio Nevalainen, Hannu Taipale, Jouko Vepsäläinen, Jukka Gynther, Tina Pedersen, Tomi Järvinen

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.21 MB

1999

26

Solid-State Characteristics of Amorphous Sodium Indomethacin Relative to Its Free Acid

Ping Tong, George Zografi

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.19 MB

1999

27

Comparison of CYP2D6 Content and Metoprolol Oxidation Between Microsomes Isolated from Human Livers and Small Intestines

Soraya Madani, Mary F. Paine, Lydia Lewis, Kenneth E. Thummel, Danny D. Shen

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.28 MB

1999

28

P-Glycoprotein-Dependent Disposition Kinetics of Tacrolimus: Studies in mdr la Knockout Mice

Koichi Yokogawa, Megumi Takahashi, Ikumi Tamai, Hiroko Konishi, Masaaki Nomura, Shuzo Moritani, Ken-ichi Miyamoto, Akira Tsuji

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 973 KB

1999

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