Volume 17; Issue 5

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Pharmaceutical Research
Volume 17; Issue 5

Pharmaceutical Research

Volume 17; Issue 5

1

The Influence of Cytotoxicity of Macromolecules and of VEGF Gene Modulated Vascular Permeability on the Enhanced Permeability and Retention Effect in Resistant Solid Tumors

Tamara Minko, Pavla Kopečkova, Vitaliy Pozharov, Keith D. Jensen, Jindřich Kopeček

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 2.45 MB

english, 2000

2

Growth Factor Delivery for Tissue Engineering

Julia E. Babensee, Larry V. McIntire, Antonios G. Mikos

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 53 KB

english, 2000

3

Oxygen Radical-Mediated Pulmonary Toxicity Induced by Some Cationic Liposomes

Sujatha Dokka, David Toledo, Xianglin Shi, Vincent Castranova, Yon Rojanasakul

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 193 KB

english, 2000

4

Role of P-Glycoprotein in Restricting Propranolol Transport in Cultured Rabbit Conjunctival Epithelial Cell Layers

Johnny J. Yang, Kwang-Jin Kim, Vincent H. L. Lee

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 396 KB

english, 2000

5

Physiological Modeling of Altered Pharmacokinetics of a Novel Anticancer Drug, UCN-01 (7-Hydroxystaurosporine), Caused by Slow Dissociation of UCN-01 from Human α1-Acid Glycoprotein

Eiichi Fuse, Akitoshi Hashimoto, Natsuko Sato, Hiromi Tanii, Takashi Kuwabara, Satoshi Kobayashi, Yuichi Sugiyama

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 347 KB

english, 2000

6

Propiverine-Induced Parkinsonism: A Case Report and a Pharmacokinetic/Pharmacodynamic Study in Mice

Hirotami Matsuo, Akiko Matsui, Risa Nasu, Hitomi Takanaga, Naohide Inoue, Fumitada Hattori, Hisakazu Ohtani, Yasufumi Sawada

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 504 KB

english, 2000

7

Sensitivity of Empirical Metrics of Rate of Absorption in Bioequivalence Studies

Arne Ring, Laszlo Tothfalusi, Laszlo Endrenyi, Michael Weiss

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 322 KB

english, 2000

8

Pharmacologic Response of a Controlled-Release PLGA Formulation for the Alpha-Melanocyte Stimulating Hormone Analog, Melanotan-I

Renu Bhardwaj, Mac E. Hadley, Robert T. Dorr, Katarina Dvorakova, Christine Brooks, James Blanchard

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 1.65 MB

english, 2000

9

Methotrexate Esters of Poly(Ethylene Oxide)-Block-Poly(2-Hydroxyethyl-L-Aspartamide). Part I: Effects of the Level of Methotrexate Conjugation on the Stability of Micelles and on Drug Release

Yu Li, Glen S. Kwon

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 299 KB

english, 2000

10

Nuclear Magnetic Resonance and Infrared Spectroscopic Analysis of Nedocromil Hydrates

Linna R. Chen, Brian E. Padden, Sudha R. Vippagunta, Eric J. Munson, David J. W. Grant

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

11

A Rapid Spectrofluorimetric Technique for Determining Drug-Serum Protein Binding Suitable for High-Throughput Screening

Hemanshu H. Parikh, Kate McElwain, Vandana Balasubramanian, Winsy Leung, Diane Wong, Marilyn E. Morris, Murali Ramanathan

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

12

Induction of Apoptosis in WEHI 231 Cells by Cationic Liposomes

Yukihiko Aramaki, Shuhei Takano, Hidetoshi Arima, Seishi Tsuchiya

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 1.01 MB

english, 2000

13

Differential Recognition of ACE Inhibitors in Xenopus Laevis Oocytes Expressing Rat PEPT1 and PEPT2

Tong Zhu, Xing-Zhen Chen, Angela Steel, Matthias A. Hediger, David E. Smith

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 497 KB

english, 2000

14

Transepithelial Transport of Diphenhydramine Across Monolayers of the Human Intestinal Epithelial Cell Line Caco-2

Hiroshi Mizuuchi, Toshiya Katsura, Yukiya Hashimoto, Ken-ichi Inui

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

15

Bioequivalence Study of Stressed and Nonstressed Hard Gelatin Capsules Using Amoxicillin as a Drug Marker and Gamma Scintigraphy to Confirm Time and GI Location of In Vivo Capsule Rupture

G. A. Digenis, E. P. Sandefer, R. C. Page, W. J. Doll, T. B. Gold, N. B. Darwazeh

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 1.39 MB

english, 2000

16

Pharmacokinetic Variability and Therapeutic Drug Monitoring Actions at Steady State

Murali Ramanathan

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

17

Subcutaneous Administration of Superoxide Dismutase Entrapped in Long Circulating Liposomes: In Vivo Fate and Therapeutic Activity in an Inflammation Model

M. Luísa Corvo, Otto C. Boerman, Wim J. G. Oyen, Joáo C. S. Jorge, M. Eugénia M. Cruz, Daan J. A. Crommelin, Gert Storm

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 162 KB

english, 2000

18

Mechanistic Studies on Surfactant-Induced Membrane Permeability Enhancement

Wei J. Xia, Hayat Onyuksel

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 260 KB

english, 2000

19

Assessment of Polymer-Polymer Interactions in Blends of HPMC and Film Forming Polymers by Modulated Temperature Differential Scanning Calorimetry

Nasser Nyamweya, Stephen W. Hoag

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000