Volume 23; Issue 6

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Pharmaceutical Research
Volume 23; Issue 6

Pharmaceutical Research

Volume 23; Issue 6

1

Protein Structural Conformation and Not Second Virial Coefficient Relates to Long-Term Irreversible Aggregation of a Monoclonal Antibody and Ovalbumin in Solution

Harminder Bajaj, Vikas K. Sharma, Advait Badkar, David Zeng, Sandeep Nema, Devendra S. Kalonia

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 627 KB

english, 2006

2

Electron Beam and Gamma Radiolysis of Solid-State Metoclopramide

Aubert Maquille, Catherine Slegers, Jean-Louis Habib, Bernard Tilquin

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 450 KB

english, 2006

3

Design and Evaluation of Celecoxib Porous Particles using Melt Sonocrystallization

Anant Paradkar, Manish Maheshwari, Ravindra Kamble, Ian Grimsey, Peter York

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

4

Adaptive Neuro-Fuzzy Modeling of Poorly Soluble Drug Formulations

Dionysios Douroumis, Leontios J. Hadjileontiadis, Alfred Fahr

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 470 KB

english, 2006

5

Enhanced Oral Paclitaxel Bioavailability After Administration of Paclitaxel-Loaded Lipid Nanocapsules

Sandra Peltier, Jean-Michel Oger, Frédéric Lagarce, William Couet, Jean-Pierre Benoît

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 376 KB

english, 2006

6

Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

Shirou Itagaki, Elangovan Gopal, Lina Zhuang, You-Jun Fei, Seiji Miyauchi, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 391 KB

english, 2006

7

Gd-DTPAl-Cystine Bisamide Copolymers as Novel Biodegradable Macromolecular Contrast Agents for MR Blood Pool Imaging

Todd L. Kaneshiro, Tianyi Ke, Eun-Kee Jeong, Dennis L. Parker, Zheng-Rong Lu

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 525 KB

english, 2006

8

Metabonomics Techniques and Applications to Pharmaceutical Research & Development

John C. Lindon, Elaine Holmes, Jeremy K. Nicholson

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 996 KB

english, 2006

9

ATP-Binding Cassette Transporter G2 Mediates the Efflux of Phototoxins on the Luminal Membrane of Retinal Capillary Endothelial Cells

Tomoko Asashima, Satoko Hori, Sumio Ohtsuki, Masanori Tachikawa, Masahiko Watanabe, Chisato Mukai, Shinji Kitagaki, Naoki Miyakoshi, Tetsuya Terasaki

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 360 KB

english, 2006

10

Characteristics of Substance P Transport Across the Blood–Brain Barrier

Arvind K. Chappa, Kenneth L. Audus, Susan M. Lunte

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 478 KB

english, 2006

11

Complement Activation by Core–Shell Poly(isobutylcyanoacrylate)–Polysaccharide Nanoparticles: Influences of Surface Morphology, Length, and Type of Polysaccharide

Isabelle Bertholon, Christine Vauthier, Denis Labarre

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 499 KB

english, 2006

12

Effects of Antipsychotic Drugs onIto,INa,Isus,IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis

William J. Crumb, Sean Ekins, R. Dustan Sarazan, James H. Wikel, Steven A. Wrighton, Christopher Carlson, Charles M. Beasley

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 617 KB

english, 2006

13

Hepatic CYP3A Expression is Attenuated in Obese Mice Fed a High-Fat Diet

Kouichi Yoshinari, Shunsuke Takagi, Teruyasu Yoshimasa, Junko Sugatani, Masao Miwa

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 627 KB

english, 2006

14

Testosterone Hormone Replacement Therapy: State-of-the-Art and Emerging Technologies

Marie-Laure Leichtnam, Hervé Rolland, Patrick Wüthrich, Richard H. Guy

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 563 KB

english, 2006

15

A Specific Picomolar Hybridization-Based ELISA Assay for the Determination of Phosphorothioate Oligonucleotides in Plasma and Cellular Matrices

Xiaohui Wei, Guowei Dai, Guido Marcucci, Zhongfa Liu, Dale Hoyt, William Blum, Kenneth K. Chan

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 976 KB

english, 2006

16

Expression of Basic Fibroblast Growth Factor Correlates with Resistance to Paclitaxel in Human Patient Tumors

Yuebo Gan, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

17

Hydrolytic Degradation and Drug Release of Ricinoleic Acid–Lactic Acid Copolyesters

Raia Slivniak, Aviva Ezra, Abraham J. Domb

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 388 KB

english, 2006

18

Glucose Partition Coefficient and Diffusivity in the Lower Skin Layers

Enam Khalil, Kosmas Kretsos, Gerald B. Kasting

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 324 KB

english, 2006

19

FTIR and nDSC as Analytical Tools for High-Concentration Protein Formulations

Susanne Matheus, Wolfgang Friess, Hanns-Christian Mahler

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 730 KB

english, 2006

20

Reverse Hexagonal Phase Nanodispersion of Monoolein and Oleic Acid for Topical Delivery of Peptides:in Vitroandin VivoSkin Penetration of Cyclosporin A

Luciana B. Lopes, Denise A. Ferreira, Daniel de Paula, M. Tereza J. Garcia, José A. Thomazini, Márcia C. A. Fantini, M. Vitória L. B. Bentley

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 572 KB

english, 2006

21

Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test

Ryusuke Takano, Kiyohiko Sugano, Atsuko Higashida, Yoshiki Hayashi, Minoru Machida, Yoshinori Aso, Shinji Yamashita

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 421 KB

english, 2006

22

Effect of Oropharyngeal Length in Drug Lung Delivery via Suspension Pressurized Metered Dose Inhalers

T. Ehtezazi, D. R. Allanson, I. D. Jenkinson, C. O'Callaghan

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 477 KB

english, 2006

23

Plasmid Engineering for Controlled and Sustained Gene Expression for Nonviral Gene Therapy

Ethlinn V. B. van Gaal, Wim E. Hennink, Daan J. A. Crommelin, Enrico Mastrobattista

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 599 KB

english, 2006

24

Nontoxic Suramin as a Chemosensitizer in Patients: Dosing Nomogram Development

Danny Chen, Sae Heum Song, M. Guillaume Wientjes, Teng Kuang Yeh, Liang Zhao, Miguel Villalona-Calero, Gregory A. Otterson, Rhonda Jensen, Michael Grever, Anthony J. Murgo, Jessie L-S. Au

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 558 KB

english, 2006

25

The Influence of Surfactant on PLGA Microsphere Glass Transition and Water Sorption: Remodeling the Surface Morphology to Attenuate the Burst Release

C. Bouissou, J. J. Rouse, R. Price, C. F. van der Walle

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 413 KB

english, 2006

26

Intestinal Absorptive Transport of the Hydrophilic Cation Ranitidine: A Kinetic Modeling Approach to Elucidate the Role of Uptake and Efflux Transporters and Paracellularvs.Transcellular Transport in Caco-2 Cells

David L. Bourdet, Gary M. Pollack, Dhiren R. Thakker

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 600 KB

english, 2006

27

Rationale for Fixed Dosing of Pertuzumab in Cancer Patients Based on Population Pharmacokinetic Analysis

Chee M. Ng, Bert L. Lum, Veronica Gimenez, Steve Kelsey, David Allison

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 893 KB

english, 2006

28

Nasal Immunization with Anthrax Protective Antigen Protein Adjuvanted with Polyriboinosinic–Polyribocytidylic Acid Induced Strong Mucosal and Systemic Immunities

Brian R. Sloat, Zhengrong Cui

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 540 KB

english, 2006

29

Canine Intestinal Contentsvs. Simulated Media for the Assessment of Solubility of Two Weak Bases in the Human Small Intestinal Contents

Lida Kalantzi, Eva Persson, Britta Polentarutti, Bertil Abrahamsson, Konstantinos Goumas, Jennifer B. Dressman, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 458 KB

english, 2006

30

Saturable Absorptive Transport of the Hydrophilic Organic Cation Ranitidine in Caco-2 Cells: Role of pH-Dependent Organic Cation Uptake System and P-Glycoprotein

David L. Bourdet, Dhiren R. Thakker

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 592 KB

english, 2006

31

CYP Induction-Mediated Drug Interactions:in VitroAssessment and Clinical Implications

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 538 KB

english, 2006

32

AAPS Update

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 115 KB

english, 2006