Volume 27; Issue 12

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Pharmaceutical Research
Volume 27; Issue 12

Pharmaceutical Research

Volume 27; Issue 12

1

Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release

Chris Oerlemans, Wouter Bult, Mariska Bos, Gert Storm, J. Frank W. Nijsen, Wim E. Hennink

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

2

Enhanced Gene and siRNA Delivery by Polycation-Modified Mesoporous Silica Nanoparticles Loaded with Chloroquine

Shanta Raj Bhattarai, Elayaraja Muthuswamy, Amit Wani, Michal Brichacek, Antonio L. Castañeda, Stephanie L. Brock, David Oupicky

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 882 KB

english, 2010

3

Bioequivalence for Topical Products—An Update

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 299 KB

english, 2010

4

Influence of Dosing Schedule on Organ Exposure to Cyclosporin in Pediatric Hematopoietic Stem Cell Transplantation: Analysis with a PBPK Model

Cécile Gérard, Nathalie Bleyzac, Pascal Girard, Gilles Freyer, Yves Bertrand, Michel Tod

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 349 KB

english, 2010

5

Quantitative Aspects of Intracellularly-Targeted Drug Delivery

David Stepensky

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 126 KB

english, 2010

6

Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles

Ebbe J. B. Nielsen, Jan M. Nielsen, Daniel Becker, Alexander Karlas, Hridayesh Prakash, Sys Z. Glud, Jonathan Merrison, Flemming Besenbacher, Thomas F. Meyer, Jørgen Kjems, Kenneth A. Howard

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 289 KB

english, 2010

7

Multifunctional Peptide-PEG Intercalating Conjugates: Programmatic of Gene Delivery to the Blood-Brain Barrier

Hongwei Zhang, Trevor Gerson, Michelle L. Varney, Rakesh K. Singh, Serguei V. Vinogradov

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

8

Real-Time UV Imaging of Nicotine Release from Transdermal Patch

Jesper Østergaard, Emil Meng-Lund, Susan Weng Larsen, Claus Larsen, Karsten Petersson, James Lenke, Henrik Jensen

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 890 KB

english, 2010

9

Structural Interpretation in Composite Systems Using Powder X-ray Diffraction: Applications of Error Propagation to the Pair Distribution Function

Michael D. Moore, Zhenqi Shi, Peter L. D. Wildfong

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

10

Population Pharmacokinetic Analysis of Blood and Joint Synovial Fluid Concentrations of Robenacoxib from Healthy Dogs and Dogs with Osteoarthritis

Hanna E. Silber, Claudia Burgener, Ingrid M. Letellier, Mathieu Peyrou, Martin Jung, Jonathan N. King, Philippe Gruet, Jerome M. Giraudel

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

11

Hyaluronic Acid/Chitosan-g-Poly(ethylene glycol) Nanoparticles for Gene Therapy: An Application for pDNA and siRNA Delivery

Manuela Raviña, Eva Cubillo, David Olmeda, Ramón Novoa-Carballal, Eduardo Fernandez-Megia, Ricardo Riguera, Alejandro Sánchez, Amparo Cano, María José Alonso

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

12

Predicting the Effect of Fed-State Intestinal Contents on Drug Dissolution

Ece Dilber Gamsiz, Mukul Ashtikar, John Crison, Walt Woltosz, Michael B. Bolger, Rebecca Lyn Carrier

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

13

Poly(ε-caprolactone)-Block-poly(ethyl Ethylene Phosphate) Micelles for Brain-Targeting Drug Delivery:In VitroandIn VivoValuation

Pengcheng Zhang, Luojuan Hu, Yucai Wang, Jun Wang, Linyin Feng, Yaping Li

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 767 KB

english, 2010

14

Amine-Modified Poly(Vinyl Alcohol)s as Non-viral Vectors for siRNA Delivery: Effects of the Degree of Amine Substitution on Physicochemical Properties and Knockdown Efficiency

Juliane Nguyen, Regina Reul, Susanne Roesler, Eyas Dayyoub, Thomas Schmehl, Tobias Gessler, Werner Seeger, Thomas H. Kissel

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 689 KB

english, 2010

15

HPMA Copolymer-Aminohexylgeldanamycin Conjugates Targeting Cell Surface Expressed GRP78 in Prostate Cancer

Nate Larson, Abhijit Ray, Alexander Malugin, Daniel B. Pike, Hamidreza Ghandehari

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 434 KB

english, 2010

16

In VitroandIn VivoAnticancer Activity of a Novel Nano-sized Formulation Based on Self-assembling Polymers Against Pancreatic Cancer

Clare Hoskins, Mehdi Ouaissi, Sofia Costa Lima, Woei Ping Cheng, Inês Loureirio, Eric Mas, Dominique Lombardo, Anabela Cordeiro-da-Silva, Ali Ouaissi, Paul Kong Thoo Lin

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 436 KB

english, 2010

17

Solubility Advantage of Amorphous Pharmaceuticals: II. Application of Quantitative Thermodynamic Relationships for Prediction of Solubility Enhancement in Structurally Diverse Insoluble Pharmaceuticals

Sharad B. Murdande, Michael J. Pikal, Ravi M. Shanker, Robin H. Bogner

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 487 KB

english, 2010

18

Lipophilicity and Transporter Influence on Blood-Retinal Barrier Permeability: A Comparison with Blood-Brain Barrier Permeability

Ken-ichi Hosoya, Atsushi Yamamoto, Shin-ichi Akanuma, Masanori Tachikawa

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

19

Cocrystalization and Simultaneous Agglomeration Using Hot Melt Extrusion

Ravindra S. Dhumal, Adrian L. Kelly, Peter York, Phil D. Coates, Anant Paradkar

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 366 KB

english, 2010

20

Topical Delivery of a Naproxen-Dithranol Co-drug:In VitroSkin Penetration, Permeation, and Staining

Wing Man Lau, Alex W White, Charles M Heard

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

21

Anticancer Drug-Loaded Nanospheres Based on Biodegradable Amphiphilic ε-Caprolactone and Carbonate Copolymers

Guo-Ping Yan, Rong-Feng Zong, Liang Li, Ting Fu, Fan Liu, Xiang-Hua Yu

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 601 KB

english, 2010

22

Delivery of Water-Soluble Drugs Using Acoustically Triggered Perfluorocarbon Double Emulsions

Mario L. Fabiilli, James A. Lee, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

23

Differential Response of Normal (PrEC) and Cancerous Human Prostate Cells (PC-3) to Phenethyl Isothiocyanate-Mediated Changes in Expression of Antioxidant Defense Genes

Anna A. Powolny, Shivendra V. Singh

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 490 KB

english, 2010

24

Polymeric Biomaterials for Gene and Drug Delivery

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 105 KB

english, 2010

25

News

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 353 KB

english, 2010