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Volume 29; Issue 11
Main
Pharmaceutical Research
Volume 29; Issue 11
Pharmaceutical Research
Volume 29; Issue 11
1
Random Mutagenesis of β-Tubulin Defines a Set of Dispersed Mutations That Confer Paclitaxel Resistance
Shanghua Yin, Changqing Zeng, Malathi Hari, Fernando Cabral
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 851 KB
Your tags:
english, 2012
2
Modeling the Yew Tree Tubulin and a Comparison of its Interaction with Paclitaxel to Human Tubulin
Jack A. Tuszynski, Travis J. A. Craddock, Jonathan Y. Mane, Khaled Barakat, Chih-Yuan Tseng, Melissa Gajewski, Philip Winter, Laleh Alisaraie, Jordan Patterson, Eric Carpenter, Weiwei Wang, Michael K.
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 959 KB
Your tags:
english, 2012
3
Drug-Loaded Polymeric Composite Skin Graft for Infection-Free Wound Healing: Fabrication, Characterization, Cell Proliferation, Migration, and Antimicrobial Activity
Anupama Mittal, Neeraj Kumar
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 829 KB
Your tags:
english, 2012
4
Elucidating the Role of Dose in the Biopharmaceutics Classification of Drugs: The Concepts of Critical Dose, EffectiveIn VivoSolubility, and Dose-Dependent BCS
Georgia Charkoftaki, Aristides Dokoumetzidis, Georgia Valsami, Panos Macheras
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 600 KB
Your tags:
english, 2012
5
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
Yan Lu, Jianjun Chen, Min Xiao, Wei Li, Duane D. Miller
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 2.36 MB
Your tags:
english, 2012
6
Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis
Zhao Wang, Jianjun Chen, Jin Wang, Sunjoo Ahn, Chien-Ming Li, Yan Lu, Vivian S. Loveless, James T. Dalton, Duane D. Miller, Wei Li
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 705 KB
Your tags:
english, 2012
7
Peloruside, Laulimalide, and Noscapine Interactions with Beta-Tubulin
Melissa M. Gajewski, Laleh Alisaraie, Jack A. Tuszynski
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 423 KB
Your tags:
english, 2012
8
Drugs Targeting Tubulin Polymerization
Wei Li
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 110 KB
Your tags:
english, 2012
9
Surface-Engineered Nanoliposomes by Chelating Ligands for Modulating the Neurotoxicity Associated with β-Amyloid Aggregates of Alzheimer’s disease
Maluta S. Mufamadi, Yahya E. Choonara, Pradeep Kumar, Girish Modi, Dinesh Naidoo, Valence M. K. Ndesendo, Lisa C. du Toit, Sunny E. Iyuke, Viness Pillay
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 951 KB
Your tags:
english, 2012
10
Acquired Resistance to Peloruside A and Laulimalide is Associated with Downregulation of Vimentin in Human Ovarian Carcinoma Cells
Arun Kanakkanthara, Pisana Rawson, Peter T. Northcote, John H. Miller
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 567 KB
Your tags:
english, 2012
11
Phospho-Sulindac (OXT-328) Inhibits the Growth of Human Lung Cancer Xenografts in Mice: Enhanced Efficacy and Mitochondria Targeting by its Formulation in Solid Lipid Nanoparticles
Rongrong Zhu, Ka-Wing Cheng, Gerardo Mackenzie, Liqun Huang, Yu Sun, Gang Xie, Kveta Vrankova, Panayiotis P. Constantinides, Basil Rigas
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 842 KB
Your tags:
english, 2012
12
Structure-Activity Relationship for Hydrophobic Salts as Viscosity-Lowering Excipients for Concentrated Solutions of Monoclonal Antibodies
Zheng Guo, Alvin Chen, Roger A. Nassar, Bernhard Helk, Claudia Mueller, Yu Tang, Kapil Gupta, Alexander M. Klibanov
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 253 KB
Your tags:
english, 2012
13
Measurement of Drug in Small Particles from Aqueous Nasal Sprays by Andersen Cascade Impactor
William H. Doub, Wallace P. Adams, Anna M. Wokovich, John C. Black, Meiyu Shen, Lucinda F. Buhse
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 264 KB
Your tags:
english, 2012
14
Computational Prediction of CNS Drug Exposure Based on a NovelIn VivoDataset
Christel A. S. Bergström, Susan A. Charman, Joseph A. Nicolazzo
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 540 KB
Your tags:
english, 2012
15
Novel Comb-Shaped PEG Modification Enhances the Osteoclastic Inhibitory Effect and Bone Delivery of Osteoprotegerin After Intravenous Administration in Ovariectomized Rats
Yoshihiro Miyaji, Yuji Kasuya, Yoshitake Furuta, Atsushi Kurihara, Masayuki Takahashi, Ken-ichi Ogawara, Takashi Izumi, Osamu Okazaki, Kazutaka Higaki
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 829 KB
Your tags:
english, 2012
16
Optimising the Delivery of Tubulin Targeting Agents through Antibody Conjugation
Gary D. Stack, John J. Walsh
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 429 KB
Your tags:
english, 2012
17
Sustained Local Delivery of Structurally Diverse HIV-1 Microbicides Released from Sublimation Enthalpy Controlled Matrices
Simi Gunaseelan, Philippe A. Gallay, Michael D. Bobardt, Charlene S. Dezzutti, Timothy Esch, Richard Maskiewicz
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 579 KB
Your tags:
english, 2012
18
Prevention of Orthopedic Device-Associated Osteomyelitis Using Oxacillin-Containing Biomineral-Binding Liposomes
Xin-Ming Liu, Yijia Zhang, Fu Chen, Irine Khutsishvili, Edward V. Fehringer, Luis A. Marky, Kenneth W. Bayles, Dong Wang
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 491 KB
Your tags:
english, 2012
19
Pharmacokinetics and Pharmacodynamics of Anti-BR3 Monoclonal Antibody in Mice
Anshu Marathe, Suhasini Iyer, Zhihua Julia Qiu, Jennifer Visich, Donald E. Mager
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 356 KB
Your tags:
english, 2012
20
Orally Bioavailable Tubulin Antagonists for Paclitaxel-Refractory Cancer
Chien-Ming Li, Yan Lu, Jianjun Chen, Terrence A. Costello, Ramesh Narayanan, Mara N. Dalton, Linda M. Snyder, Sunjoo Ahn, Wei Li, Duane D. Miller, James T. Dalton
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 336 KB
Your tags:
english, 2012
21
Novel Water-Soluble Substituted Pyrrolo[3,2-d]pyrimidines: Design, Synthesis, and Biological Evaluation as Antitubulin Antitumor Agents
Aleem Gangjee, Roheeth K. Pavana, Wei Li, Ernest Hamel, Cara Westbrook, Susan L. Mooberry
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 343 KB
Your tags:
english, 2012
22
A New Strategy to Rapidly Evaluate Kinetics of Glucuronide Efflux by Breast Cancer Resistance Protein (BCRP/ABCG2)
Baojian Wu, Wen Jiang, Taijun Yin, Song Gao, Ming Hu
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 602 KB
Your tags:
english, 2012
23
Formulation and Characterization of Polyester/Polycarbonate Nanoparticles for Delivery of a Novel Microtubule Destabilizing Agent
Vaibhav Mundra, Yan Lu, Michael Danquah, Wei Li, Duane D. Miller, Ram I. Mahato
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 709 KB
Your tags:
english, 2012
24
AAPS Connection
Journal:
Pharmaceutical Research
Year:
2012
Language:
english
File:
PDF, 322 KB
Your tags:
english, 2012
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