Volume 7; Issue 6

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Pharmaceutical Research
Volume 7; Issue 6

Pharmaceutical Research

Volume 7; Issue 6

1

Simultaneous Modeling of the Pharmacokinetic and Pharmacodynamic Properties of Benzodiazepines. II. Triazolam

Samir K. Gupta, Everett H. Ellinwood, Arlene M. Nikaido, Douglas G. Heatherly

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.17 MB

1990

2

Pharmacokinetics of a Mouse/Human Chimeric Monoclonal Antibody (C-17-1 A) in Metastatic Adenocarcinoma Patients

John M. Trang, Albert F. LoBuglio, Richard H. Wheeler, Elizabeth B. Harvey, Lee Sun, John Ghrayeb, M. B. Khazaeli

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.02 MB

1990

3

Testing of Insulin Hexamer-Stabilizing Ligands Using Theoretical Binding, Microcalorimetry, and Nuclear Magnetic Resonance (NMR) Line Broadening Techniques

Scott E. McGraw, David J. Craik, Siegfried Lindenbaum

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.00 MB

1990

4

Pharmaceutical Usefulness of Hydroxypropylcyclodextrins: "E Pluribus Unum” Is an Essential Feature

C. Trinadha Rao, Henry M. Fales, Josef Pitha

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 813 KB

1990

5

Oleic Acid: Its Effects on Stratum Corneum in Relation to (Trans)Dermal Drug Delivery

Michael L. Francoeur, Guia M. Golden, Russell O. Potts

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.17 MB

1990

6

Binding of Drugs in Milk: The Role of Casein in Milk Protein Binding

Thomas Stebler, Theodor W. Guentert

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 817 KB

1990

7

Effect of Dextran Sulfate on Renal Accumulation of Gentamicin

Shinji Kikuchi, Yukihiko Aramaki, Homare Nonaka, Seishi Tsuchiya

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 763 KB

1990

8

The Relationship Between the Glass Transition Temperature and Water Vapor Absorption by Poly(vinylpyrrolidone)

Cynthia A. Oksanen, George Zografi

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 667 KB

1990

9

Characterization of Epidermal Growth Factor Receptors on Plasma Membranes Isolated from Rat Gastric Mucosa

Ryohei Hori, Hisashi Nomura, Seigo Iwakawa, Katsuhiko Okumura

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.03 MB

1990

10

Comparisons ofin VitroNitroglycerin (TNG) Flux Across Yucatan Pig, Hairless Mouse, and Human Skins

Mary E. Roberts, Karl R. Mueller

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 613 KB

1990

11

BOOK REVIEWS

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 94 KB

1990

12

Pulmonary Delivery of Peptide Drugs: Effect of Particle Size on Bioavailability of Leuprolide Acetate in Healthy Male Volunteers

Akwete Adjei, Julie Garren

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 926 KB

1990

13

Development of a Preformulation Lipophilicity Screen Utilizing a C-18-Derivatized Polystyrene-Divinylbenzene High-Performance Liquid Chromatographic (HPLC) Column

William J. Lambert, Latrelle A. Wright

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.55 MB

1990

14

Chemical Pathways of Peptide Degradation. I. Deamidation of Adrenocorticotropic Hormone

Neelima P. Bhatt, Kamlesh Patel, Ronald T. Borchardt

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.46 MB

1990

15

The Use of Microcalorimetry to Measure Thermodynamic Parameters of the Binding of Ligands to Insulin

Scott E. McGraw, Siegfried Lindenbaum

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 881 KB

1990

16

Formulation and Dosage Form Design in Drug-Induced Topical Irritation of the Gastrointestinal Tract

John W. Fara, Robert E. Myrback

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 4.88 MB

1990

17

Constant-Rate Intravenous Infusion Methods for Estimating Steady-State Volumes of Distribution and Mean Residence Times in the Body for Drugs Undergoing Reversible Metabolism

Haiyung Cheng, William J. Jusko

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 660 KB

1990

18

Metabolic Conversion of Cyoctol During Skin Passage in Humans

Rokus A. de Zeeuw, Renella E. Herder, Johann W. Wiechers, Ben F. H. Drenth

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 707 KB

1990

19

The Effect of Physical Aging on the Dissolution Rate of Anionic Polyelectrolytes

Christopher M. Sinko, Albert F. Yee, Gordon L. Amidon

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 922 KB

1990

20

Application of a Brain-Targeting Chemical Delivery System to 9-Amino-1,2,3,4-Tetrahydroacridine

Emil Pop, Katalin Prókai-Tátrai, James D. Scott, Marcus E. Brewster, Nicholas Bodor

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.26 MB

1990

21

Effects of Amantadine on Dopaminergic Neurons in Discrete Regions of the Rat Brain

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 512 KB

1990

22

Influence of Absorption Rate, Dosing Frequency, and Intrinsic Pharmacokinetic Profile on Steady-State Drug Concentrations

Michael A. Eldon, Wayne A. Colburn

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 515 KB

1990

23

Association News and Announcements

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 175 KB

1990