Volume 117

Pharmacological Research

Volume 117

1

A story of metformin-butyrate synergism to control various pathological conditions as a consequence of gut microbiome modification: Genesis of a wonder drug?

Maniar, Kunal, Moideen, Amal, Mittal, Ankur, Patil, Amol, Chakrabarti, Amitava, Banerjee, Dibyajyoti

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

2

Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: Pharmacological and metabolism-based investigation

Poudyal, Hemant, Lemonakis, Nikolaos, Efentakis, Panagiotis, Gikas, Evangelos, Halabalaki, Maria, Andreadou, Ioanna, Skaltsounis, Leandros, Brown, Lindsay

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

3

Re-calculating! Navigating through the osteosarcoma treatment roadblock

McGuire, J., Utset-Ward, T.J., Reed, D.R., Lynch, C.C.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 786 KB

english, 2017

4

Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis

Kanashiro, Alexandre, Sônego, Fabiane, Ferreira, Raphael G., Castanheira, Fernanda V.S., Leite, Caio A., Borges, Vanessa F., Nascimento, Daniele C., Cólon, David F., Alves-Filho, José Carlos, Ulloa, L

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 759 KB

english, 2017

5

Allosteric MEK1/2 inhibitors including cobimetanib and trametinib in the treatment of cutaneous melanomas

Roskoski, Robert

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

6

Potentiation of hepatic stellate cell activation by extracellular ATP is dependent on P2X7R-mediated NLRP3 inflammasome activation

Jiang, Shuang, Zhang, Yu, Zheng, Jin-Hua, Li, Xia, Yao, You-Li, Wu, Yan-Ling, Song, Shun-Zong, Sun, Peng, Nan, Ji-Xing, Lian, Li-Hua

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

7

Advanced technologies charting a new path for traditional Chinese medicine drug discovery

Leung, Elaine Lai-Han, Clementi, Emilio, Wong, W.S. Fred

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 196 KB

english, 2017

8

A 2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway

Merighi, Stefania, Bencivenni, Serena, Vincenzi, Fabrizio, Varani, Katia, Borea, Pier Andrea, Gessi, Stefania

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 2.44 MB

english, 2017

9

Mapping transmembrane residues of proteinase activated receptor 2 (PAR 2 ) that influence ligand-modulated calcium signaling

Suen, J.Y., Adams, M.N., Lim, J., Madala, P.K., Xu, W., Cotterell, A.J., He, Y., Yau, M.K., Hooper, J.D., Fairlie, D.P.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.72 MB

english, 2017

10

sec -Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain

Kaufmann, Dan, West, Peter J., Smith, Misty D., Yagen, Boris, Bialer, Meir, Devor, Marshall, White, H. Steve, Brennan, K.C.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

11

Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome

Igarashi, Miki, Narayanaswami, Vidya, Kimonis, Virginia, Galassetti, Pietro M., Oveisi, Fariba, Jung, Kwang-Mook, Piomelli, Daniele

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 745 KB

english, 2017

12

Resveratrol regulates gene transcription via activation of stimulus-responsive transcription factors

Thiel, Gerald, Rössler, Oliver G.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 887 KB

english, 2017

13

Pharmacological chaperone approaches for rescuing GPCR mutants: Current state, challenges, and screening strategies

Beerepoot, Pieter, Nazari, Reza, Salahpour, Ali

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 673 KB

english, 2017

14

Effect of lysosomotropic molecules on cellular homeostasis

Kuzu, Omer F., Toprak, Mesut, Noory, M. Anwar, Robertson, Gavin P.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 547 KB

english, 2017

15

Polymer-coated nanoparticles: Carrier platforms for hydrophobic water- and air-sensitive metallo-organic compounds

Valdeperez, Daniel, Wang, Tianqiang, Eußner, Jens P., Weinert, Bastian, Hao, Jianyuan, Parak, Wolfgang J., Dehnen, Stefanie, Pelaz, Beatriz

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 909 KB

english, 2017

16

Prolonged infusion of sedatives and analgesics in adult intensive care patients: A systematic review of pharmacokinetic data reporting and quality of evidence

Tse, Andrew H.W., Ling, Lowell, Joynt, Gavin M., Lee, Anna

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

17

Multiple nickel-sensitive targets elicit cardiac arrhythmia in isolated mouse hearts after pituitary adenylate cyclase-activating polypeptide-mediated chronotropy

Tevoufouet, Etienne E., Nembo, Erastus N., Distler, Fabian, Neumaier, Felix, Hescheler, Jürgen, Nguemo, Filomain, Schneider, Toni

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

18

Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity

Rezaee, Ramin, Momtazi, Amir Abbas, Monemi, Alireza, Sahebkar, Amirhossein

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 570 KB

english, 2017

19

Melatonin as a promising agent of regulating stem cell biology and its application in disease therapy

Zhang, Shuo, Chen, Simon, Li, Yuan, Liu, Yu

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 723 KB

english, 2017

20

Vitamin D in autoimmune rheumatic diseases: A view inside gender differences

Vasile, Massimiliano, Corinaldesi, Clarissa, Antinozzi, Cristina, Crescioli, Clara

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 902 KB

english, 2017

21

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

Pati, Maria Laura, Groza, Diana, Riganti, Chiara, Kopecka, Joanna, Niso, Mauro, Berardi, Francesco, Hager, Sonja, Heffeter, Petra, Hirai, Miwa, Tsugawa, Hitoshi, Kabe, Yasuaki, Suematsu, Makoto, Abate

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

22

Gender related differences in treatment and response to statins in primary and secondary cardiovascular prevention: The never-ending debate

Cangemi, Roberto, Romiti, Giulio Francesco, Campolongo, Giuseppe, Ruscio, Eleonora, Sciomer, Susanna, Gianfrilli, Daniele, Raparelli, Valeria

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 468 KB

english, 2017

23

Passive drug permeation through membranes and cellular distribution

Scott, D.O., Ghosh, A., Di, L., Maurer, T.S.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

24

[6]-gingerol and [6]-shogaol, active ingredients of the traditional Japanese medicine hangeshashinto, relief oral ulcerative mucositis-induced pain via action on Na + channels

Hitomi, Suzuro, Ono, Kentaro, Terawaki, Kiyoshi, Matsumoto, Chinami, Mizuno, Keita, Yamaguchi, Kiichiro, Imai, Ryota, Omiya, Yuji, Hattori, Tomohisa, Kase, Yoshio, Inenaga, Kiyotoshi

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

25

Anaplastic lymphoma kinase (ALK) inhibitors in the treatment of ALK-driven lung cancers

Roskoski, Robert

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

26

Dysregulation of cytokine mediated chemotherapy induced cognitive impairment

Ren, Xiaojia, St. Clair, Daret K., Butterfield, D.Allan

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 731 KB

english, 2017

27

Downstream Regulatory Element Antagonist Modulator (DREAM), a target for anti-thrombotic agents

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

28

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration

Xu, Daoliang, Jin, Haiming, Wen, Jianxia, Chen, Jiaoxiang, Chen, Deheng, Cai, Ningyu, Wang, Yongli, Wang, Jianle, Chen, Yu, Zhang, Xiaolei, Wang, Xiangyang

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 976 KB

english, 2017

29

Targeting EGFR T790M mutation in NSCLC: From biology to evaluation and treatment

Passaro, Antonio, Guerini-Rocco, Elena, Pochesci, Alessia, Vacirca, Davide, Spitaleri, Gianluca, Catania, Chiara Matilde, Rappa, Alessandra, Barberis, Massimo, de Marinis, Filippo

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 724 KB

english, 2017

30

Pharmacological strategies to target oncogenic KRAS signaling in pancreatic cancer

Chuang, Hsiao-Ching, Huang, Po-Hsien, Kulp, Samuel K., Chen, Ching-Shih

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

31

An update on the physiological and therapeutic relevance of GPCR oligomers

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 967 KB

english, 2017

32

Balancing thromboembolic and bleeding risk with non-vitamin K antagonist oral anticoagulants (NOACs): A systematic review and meta-analysis on gender differences

Proietti, Marco, Cheli, Paola, Basili, Stefania, Mazurek, Michal, Lip, Gregory Y.H.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

33

Are the innate and adaptive immune systems setting hypertension on fire?

Bomfim, Gisele F., Rodrigues, Fernanda Luciano, Carneiro, Fernando S.

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.11 MB

english, 2017

34

Resveratrol supplementation and plasma adipokines concentrations? A systematic review and meta-analysis of randomized controlled trials

Mohammadi-Sartang, Mohsen, Mazloom, Zohreh, Sohrabi, Zahra, Sherafatmanesh, Saeed, Barati-Boldaji, Reza

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

35

Editorial Board

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 56 KB

english, 2017

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