Volume 7; Issue 4

PLoS Computational Biology

Volume 7; Issue 4

1

Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the Anti-Cancer Effect of Nelfinavir

Xie, Li, Evangelidis, Thomas, Xie, Lei, Bourne, Philip E., Nussinov, Ruth

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 3.16 MB

english, 2011

2

Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics

Bucher, Denis, Grant, Barry J., Markwick, Phineus R., McCammon, J. Andrew, Nussinov, Ruth

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 246 KB

english, 2011

3

Network Archaeology: Uncovering Ancient Networks from Present-Day Interactions

Navlakha, Saket, Kingsford, Carl, Bader, Joel S.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 410 KB

english, 2011

4

The Morphology of the Rat Vibrissal Array: A Model for Quantifying Spatiotemporal Patterns of Whisker-Object Contact

Towal, R. Blythe, Quist, Brian W., Gopal, Venkatesh, Solomon, Joseph H., Hartmann, Mitra J. Z., Friston, Karl J.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

5

In Silico Elucidation of the Recognition Dynamics of Ubiquitin

Long, Dong, Brüschweiler, Rafael, Nussinov, Ruth

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 216 KB

english, 2011

6

A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model

McCaw, James M., Arinaminpathy, Nimalan, Hurt, Aeron C., McVernon, Jodie, McLean, Angela R., Fraser, Christophe

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

7

Discovering Biological Progression Underlying Microarray Samples

Qiu, Peng, Gentles, Andrew J., Plevritis, Sylvia K., Reed, Jennifer L.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 225 KB

english, 2011

8

Quantifying the Relative Contributions of Divisive and Subtractive Feedback to Rhythm Generation

Tabak, Joël, Rinzel, John, Bertram, Richard, Gutkin, Boris S.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 407 KB

english, 2011

9

Linking Microscopic Spatial Patterns of Tissue Destruction in Emphysema to Macroscopic Decline in Stiffness Using a 3D Computational Model

Parameswaran, Harikrishnan, Majumdar, Arnab, Suki, Béla, Bourne, Philip E.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

10

Disentangling the Roles of Approach, Activation and Valence in Instrumental and Pavlovian Responding

Huys, Quentin J. M., Cools, Roshan, Gölzer, Martin, Friedel, Eva, Heinz, Andreas, Dolan, Raymond J., Dayan, Peter, Rangel, Antonio

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 490 KB

english, 2011

11

MDCK Cystogenesis Driven by Cell Stabilization within Computational Analogues

Engelberg, Jesse A., Datta, Anirban, Mostov, Keith E., Hunt, C. Anthony, McCulloch, Andrew D.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 398 KB

english, 2011

12

A Stochastic Model of Latently Infected Cell Reactivation and Viral Blip Generation in Treated HIV Patients

Conway, Jessica M., Coombs, Daniel, Fraser, Christophe

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 513 KB

english, 2011

13

Cell-Sorting at the A/P Boundary in the Drosophila Wing Primordium: A Computational Model to Consolidate Observed Non-Local Effects of Hh Signaling

Schilling, Sabine, Willecke, Maria, Aegerter-Wilmsen, Tinri, Cirpka, Olaf A., Basler, Konrad, von Mering, Christian, Shvartsman, Stanislav

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 301 KB

english, 2011

14

Modification of Gene Duplicability during the Evolution of Protein Interaction Network

D'Antonio, Matteo, Ciccarelli, Francesca D., Ouzounis, Christos A.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

15

A Third Measure-Metastable State in the Dynamics of Spontaneous Shape Change in Healthy Human's White Cells

Selz, Karen A., Shlesinger, Michael

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

16

Multi-Scaled Explorations of Binding-Induced Folding of Intrinsically Disordered Protein Inhibitor IA3 to its Target Enzyme

Wang, Jin, Wang, Yong, Chu, Xiakun, Hagen, Stephen J., Han, Wei, Wang, Erkang, Hummer, Gerhard

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 338 KB

english, 2011

17

A Comparison of Mathematical Models for Polarization of Single Eukaryotic Cells in Response to Guided Cues

Jilkine, Alexandra, Edelstein-Keshet, Leah, Haugh, Jason M.

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 447 KB

english, 2011

18

Minimum Information About a Simulation Experiment (MIASE)

Waltemath, Dagmar, Adams, Richard, Beard, Daniel A., Bergmann, Frank T., Bhalla, Upinder S., Britten, Randall, Chelliah, Vijayalakshmi, Cooling, Michael T., Cooper, Jonathan, Crampin, Edmund J., Garny

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011