Volume 15; Issue 12

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PLoS Genetics
Volume 15; Issue 12

PLoS Genetics

Volume 15; Issue 12

1

Experimental population modification of the malaria vector mosquito, Anopheles stephensi

Pham, Thai Binh, Phong, Celine Hien, Bennett, Jared B., Hwang, Kristy, Jasinskiene, Nijole, Parker, Kiona, Stillinger, Drusilla, Marshall, John M., Carballar-Lejarazú, Rebeca, James, Anthony A., Despl

Journal:

Year:

2019

Language:

english

File:

PDF, 4.18 MB

english, 2019

2

Correction: Origins of DNA replication

Journal:

Year:

2019

Language:

english

File:

PDF, 432 KB

english, 2019

3

Common alleles of CMT2 and NRPE1 are major determinants of CHH methylation variation in Arabidopsis thaliana

Sasaki, Eriko, Kawakatsu, Taiji, Ecker, Joseph R., Nordborg, Magnus, Köhler, Claudia

Journal:

Year:

2019

Language:

english

File:

PDF, 5.57 MB

english, 2019

4

Identification of avoidance genes through neural pathway-specific forward optogenetics

Marques, Filipe, Saro, Gabriella, Lia, Andrei-Stefan, Poole, Richard J., Falquet, Laurent, Glauser, Dominique A., Ashrafi, Kaveh

Journal:

Year:

2019

Language:

english

File:

PDF, 3.54 MB

english, 2019

5

Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives

Caballero, Madison, Seidman, Daniel N., Qiao, Ying, Sannerud, Jens, Dyer, Thomas D., Lehman, Donna M., Curran, Joanne E., Duggirala, Ravindranath, Blangero, John, Carmi, Shai, Williams, Amy L., Marchi

Journal:

Year:

2019

Language:

english

File:

PDF, 4.17 MB

english, 2019

6

Identification of novel genes involved in phosphate accumulation in Lotus japonicus through Genome Wide Association mapping of root system architecture and anion content

Giovannetti, Marco, Göschl, Christian, Dietzen, Christof, Andersen, Stig U., Kopriva, Stanislav, Busch, Wolfgang, Gutjahr, Caroline

Journal:

Year:

2019

Language:

english

File:

PDF, 5.86 MB

english, 2019

7

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Taborska, Eliska, Pasulka, Josef, Malik, Radek, Horvat, Filip, Jenickova, Irena, Jelić Matošević, Zoe, Svoboda, Petr, He, Lin

Journal:

Year:

2019

Language:

english

File:

PDF, 7.54 MB

english, 2019

8

Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy

Verma, Mayank, Shimizu-Motohashi, Yuko, Asakura, Yoko, Ennen, James P., Bosco, Jennifer, Zhou, Zhiwei, Fong, Guo-Hua, Josiah, Serene, Keefe, Dennis, Asakura, Atsushi, Cox, Gregory A.

Journal:

Year:

2019

Language:

english

File:

PDF, 4.16 MB

english, 2019

9

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Kowalski, Madeline H., Qian, Huijun, Hou, Ziyi, Rosen, Jonathan D., Tapia, Amanda L., Shan, Yue, Jain, Deepti, Argos, Maria, Arnett, Donna K., Avery, Christy, Barnes, Kathleen C., Becker, Lewis C., Bi

Journal:

Year:

2019

Language:

english

File:

PDF, 2.22 MB

english, 2019

10

The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor

Coe, Elizabeth A., Tan, Jennifer Y., Shapiro, Michael, Louphrasitthiphol, Pakavarin, Bassett, Andrew R., Marques, Ana C., Goding, Colin R., Vance, Keith W., Widlund, Hans

Journal:

Year:

2019

Language:

english

File:

PDF, 2.84 MB

english, 2019

11

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging

Walzer, Katelyn A., Fradin, Hélène, Emerson, Liane Y., Corcoran, David L., Chi, Jen-Tsan, Sirugo, Giorgio

Journal:

Year:

2019

Language:

english

File:

PDF, 6.67 MB

english, 2019

12

Drosophila RpS12 controls translation, growth, and cell competition through Xrp1

Ji, Zhejun, Kiparaki, Marianthi, Folgado, Virginia, Kumar, Amit, Blanco, Jorge, Rimesso, Gerard, Chuen, Jacky, Liu, Yang, Zheng, Deyou, Baker, Nicholas E., Su, Tin Tin

Journal:

Year:

2019

Language:

english

File:

PDF, 12.40 MB

english, 2019

13

Hybridization promotes asexual reproduction in Caenorhabditis nematodes

Lamelza, Piero, Young, Janet M., Noble, Luke M., Caro, Lews, Isakharov, Arielle, Palanisamy, Meenakshi, Rockman, Matthew V., Malik, Harmit S., Ailion, Michael, Delattre, Marie

Journal:

Year:

2019

Language:

english

File:

PDF, 9.64 MB

english, 2019

14

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity

Maazi, Hadi, Hartiala, Jaana A., Suzuki, Yuzo, Crow, Amanda L., Shafiei Jahani, Pedram, Lam, Jonathan, Patel, Nisheel, Rigas, Diamanda, Han, Yi, Huang, Pin, Eskin, Eleazar, Lusis, Aldons. J., Gillilan

Journal:

Year:

2019

Language:

english

File:

PDF, 3.52 MB

english, 2019

15

Genetic determinants of genus—Level glycan diversity in a bacterial protein glycosylation system

Hadjineophytou, Chris, Anonsen, Jan Haug, Wang, Nelson, Ma, Kevin C., Viburiene, Raimonda, Vik, Åshild, Harrison, Odile B., Maiden, Martin C. J., Grad, Yonatan H., Koomey, Michael, Casadesús, Josep

Journal:

Year:

2019

Language:

english

File:

PDF, 2.76 MB

english, 2019

16

Phosphatidylserine synthetase regulates cellular homeostasis through distinct metabolic mechanisms

Yang, Xiao, Liang, Jingjing, Ding, Long, Li, Xia, Lam, Sin-Man, Shui, Guanghou, Ding, Mei, Huang, Xun, Teleman, Aurelio A.

Journal:

Year:

2019

Language:

english

File:

PDF, 18.67 MB

english, 2019

17

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

de Castro, Patrícia Alves, Colabardini, Ana Cristina, Manfiolli, Adriana Oliveira, Chiaratto, Jéssica, Silva, Lilian Pereira, Mattos, Eliciane Cevolani, Palmisano, Giuseppe, Almeida, Fausto, Persinoti

Journal:

Year:

2019

Language:

english

File:

PDF, 12.57 MB

english, 2019

18

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4

Garrett, Andrew M., Bosch, Peter J., Steffen, David M., Fuller, Leah C., Marcucci, Charles G., Koch, Alexis A., Bais, Preeti, Weiner, Joshua A., Burgess, Robert W., Garcia-Bassets, Ivan

Journal:

Year:

2019

Language:

english

File:

PDF, 14.97 MB

english, 2019

19

Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII

Pinar, Mario, Arias-Palomo, Ernesto, de los Ríos, Vivian, Arst, Herbert N., Peñalva, Miguel A., Idnurm, Alexander

Journal:

Year:

2019

Language:

english

File:

PDF, 8.33 MB

english, 2019

20

BLISTER-regulated vegetative growth is dependent on the protein kinase domain of ER stress modulator IRE1A in Arabidopsis thaliana

Hong, Zheng-Hui, Qing, Tao, Schubert, Daniel, Kleinmanns, Julia Anna, Liu, Jian-Xiang, Qu, Li-Jia

Journal:

Year:

2019

Language:

english

File:

PDF, 13.89 MB

english, 2019

21

Cell elimination strategies upon identity switch via modulation of apterous in Drosophila wing disc

Klipa, Olga, Hamaratoglu, Fisun, Schweisguth, François

Journal:

Year:

2019

Language:

english

File:

PDF, 14.27 MB

english, 2019

22

A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability

Reitz, Diedre, Grubb, Jennifer, Bishop, Douglas K., Lichten, Michael

Journal:

Year:

2019

File:

PDF, 8.43 MB

2019

23

Selective breeding modifies mef2ca mutant incomplete penetrance by tuning the opposing Notch pathway

Sucharov, Juliana, Ray, Kuval, Brooks, Elliott P., Nichols, James T., Miller, Craig T.

Journal:

Year:

2019

File:

PDF, 25.99 MB

2019

24

Modulators of hormonal response regulate temporal fate specification in the Drosophila brain

Marchetti, Giovanni, Tavosanis, Gaia, Wang, Hongyan

Journal:

Year:

2019

File:

PDF, 21.89 MB

2019

25

An autism-causing calcium channel variant functions with selective autophagy to alter axon targeting and behavior

Buddell, Tyler, Friedman, Vladislav, Drozd, Cody J., Quinn, Christopher C., Frankel, Wayne N.

Journal:

Year:

2019

File:

PDF, 1.49 MB

2019

26

Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

Day, Felix, Karaderi, Tugce, Jones, Michelle R., Meun, Cindy, He, Chunyan, Drong, Alex, Kraft, Peter, Lin, Nan, Huang, Hongyan, Broer, Linda, Magi, Reedik, Saxena, Richa, Laisk, Triin, Urbanek, Margri

Journal:

Year:

2019

File:

PDF, 326 KB

2019

27

Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans

Shomer, Naomi, Kadhim, Alexandre Zacharie, Grants, Jennifer Margaret, Cheng, Xuanjin, Alhusari, Deema, Bhanshali, Forum, Poon, Amy Fong-Yuk, Lee, Michelle Ying Ya, Muhuri, Anik, Park, Jung In, Shih, J

Journal:

Year:

2019

File:

PDF, 8.10 MB

2019

28

An MCM family protein promotes interhomolog recombination by preventing precocious intersister repair of meiotic DSBs

Tian, Miao, Loidl, Josef, Bishop, Douglas K.

Journal:

Year:

2019

File:

PDF, 12.82 MB

2019

29

Leveraging allelic imbalance to refine fine-mapping for eQTL studies

Zou, Jennifer, Hormozdiari, Farhad, Jew, Brandon, Castel, Stephane E., Lappalainen, Tuuli, Ernst, Jason, Sul, Jae Hoon, Eskin, Eleazar, Wen, Xiaoquan

Journal:

Year:

2019

File:

PDF, 3.57 MB

2019

30

A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21

Chernus, Jonathan M., Allen, Emily G., Zeng, Zhen, Hoffman, Eva R., Hassold, Terry J., Feingold, Eleanor, Sherman, Stephanie L., Hawley, R. Scott

Journal:

Year:

2019

File:

PDF, 10.55 MB

2019

31

Architecture of the Escherichia coli nucleoid

Verma, Subhash C., Qian, Zhong, Adhya, Sankar L.

Journal:

Year:

2019

File:

PDF, 3.97 MB

2019

32

Zfh2 controls progenitor cell activation and differentiation in the adult Drosophila intestinal absorptive lineage

Rojas Villa, Sebastian E., Meng, Fanju W., Biteau, Benoît, Teleman, Aurelio A.

Journal:

Year:

2019

File:

PDF, 23.05 MB

2019

33

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval

King, Emily A., Davis, J. Wade, Degner, Jacob F., Marchini, Jonathan

Journal:

Year:

2019

File:

PDF, 1.12 MB

2019

34

Coacting enhancers can have complementary functions within gene regulatory networks and promote canalization

Dunipace, Leslie, Ákos, Zsuzsa, Stathopoulos, Angelike, Desplan, Claude

Journal:

Year:

2019

File:

PDF, 20.86 MB

2019

35

Selection signatures in goats reveal copy number variants underlying breed-defining coat color phenotypes

Henkel, Jan, Saif, Rashid, Jagannathan, Vidhya, Schmocker, Corinne, Zeindler, Flurina, Bangerter, Erika, Herren, Ursula, Posantzis, Dimitris, Bulut, Zafer, Ammann, Philippe, Drögemüller, Cord, Flury,

Journal:

Year:

2019

File:

PDF, 4.26 MB

2019

36

Genetic variation in GC and CYP2R1 affects 25-hydroxyvitamin D concentration and skeletal parameters: A genome-wide association study in 24-month-old Finnish children

Kämpe, Anders, Enlund-Cerullo, Maria, Valkama, Saara, Holmlund-Suila, Elisa, Rosendahl, Jenni, Hauta-alus, Helena, Pekkinen, Minna, Andersson, Sture, Mäkitie, Outi, Richards, J. Brent

Journal:

Year:

2019

File:

PDF, 4.84 MB

2019

37

Experimental population modification of the malaria vector mosquito, Anopheles stephensi

Pham, Thai Binh, Phong, Celine Hien, Bennett, Jared B., Hwang, Kristy, Jasinskiene, Nijole, Parker, Kiona, Stillinger, Drusilla, Marshall, John M., Carballar-Lejarazú, Rebeca, James, Anthony A., Despl

Journal:

Year:

2019

File:

PDF, 4.18 MB

2019

38

Correction: Origins of DNA replication

Journal:

Year:

2019

File:

PDF, 432 KB

2019

39

Common alleles of CMT2 and NRPE1 are major determinants of CHH methylation variation in Arabidopsis thaliana

Sasaki, Eriko, Kawakatsu, Taiji, Ecker, Joseph R., Nordborg, Magnus, Köhler, Claudia

Journal:

Year:

2019

File:

PDF, 5.57 MB

2019

40

Identification of avoidance genes through neural pathway-specific forward optogenetics

Marques, Filipe, Saro, Gabriella, Lia, Andrei-Stefan, Poole, Richard J., Falquet, Laurent, Glauser, Dominique A., Ashrafi, Kaveh

Journal:

Year:

2019

File:

PDF, 3.54 MB

2019

41

Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives

Caballero, Madison, Seidman, Daniel N., Qiao, Ying, Sannerud, Jens, Dyer, Thomas D., Lehman, Donna M., Curran, Joanne E., Duggirala, Ravindranath, Blangero, John, Carmi, Shai, Williams, Amy L., Marchi

Journal:

Year:

2019

File:

PDF, 4.17 MB

2019

42

Identification of novel genes involved in phosphate accumulation in Lotus japonicus through Genome Wide Association mapping of root system architecture and anion content

Giovannetti, Marco, Göschl, Christian, Dietzen, Christof, Andersen, Stig U., Kopriva, Stanislav, Busch, Wolfgang, Gutjahr, Caroline

Journal:

Year:

2019

File:

PDF, 5.86 MB

2019

43

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Taborska, Eliska, Pasulka, Josef, Malik, Radek, Horvat, Filip, Jenickova, Irena, Jelić Matošević, Zoe, Svoboda, Petr, He, Lin

Journal:

Year:

2019

File:

PDF, 7.54 MB

2019

44

Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy

Verma, Mayank, Shimizu-Motohashi, Yuko, Asakura, Yoko, Ennen, James P., Bosco, Jennifer, Zhou, Zhiwei, Fong, Guo-Hua, Josiah, Serene, Keefe, Dennis, Asakura, Atsushi, Cox, Gregory A.

Journal:

Year:

2019

File:

PDF, 4.16 MB

2019

45

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Kowalski, Madeline H., Qian, Huijun, Hou, Ziyi, Rosen, Jonathan D., Tapia, Amanda L., Shan, Yue, Jain, Deepti, Argos, Maria, Arnett, Donna K., Avery, Christy, Barnes, Kathleen C., Becker, Lewis C., Bi

Journal:

Year:

2019

File:

PDF, 2.22 MB

2019

46

The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor

Coe, Elizabeth A., Tan, Jennifer Y., Shapiro, Michael, Louphrasitthiphol, Pakavarin, Bassett, Andrew R., Marques, Ana C., Goding, Colin R., Vance, Keith W., Widlund, Hans

Journal:

Year:

2019

File:

PDF, 2.84 MB

2019

47

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging

Walzer, Katelyn A., Fradin, Hélène, Emerson, Liane Y., Corcoran, David L., Chi, Jen-Tsan, Sirugo, Giorgio

Journal:

Year:

2019

File:

PDF, 6.67 MB

2019

48

Drosophila RpS12 controls translation, growth, and cell competition through Xrp1

Ji, Zhejun, Kiparaki, Marianthi, Folgado, Virginia, Kumar, Amit, Blanco, Jorge, Rimesso, Gerard, Chuen, Jacky, Liu, Yang, Zheng, Deyou, Baker, Nicholas E., Su, Tin Tin

Journal:

Year:

2019

File:

PDF, 12.40 MB

2019

49

Hybridization promotes asexual reproduction in Caenorhabditis nematodes

Lamelza, Piero, Young, Janet M., Noble, Luke M., Caro, Lews, Isakharov, Arielle, Palanisamy, Meenakshi, Rockman, Matthew V., Malik, Harmit S., Ailion, Michael, Delattre, Marie

Journal:

Year:

2019

File:

PDF, 9.64 MB

2019

50

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity

Maazi, Hadi, Hartiala, Jaana A., Suzuki, Yuzo, Crow, Amanda L., Shafiei Jahani, Pedram, Lam, Jonathan, Patel, Nisheel, Rigas, Diamanda, Han, Yi, Huang, Pin, Eskin, Eleazar, Lusis, Aldons. J., Gillilan

Journal:

Year:

2019

File:

PDF, 3.52 MB

2019

51

Genetic determinants of genus—Level glycan diversity in a bacterial protein glycosylation system

Hadjineophytou, Chris, Anonsen, Jan Haug, Wang, Nelson, Ma, Kevin C., Viburiene, Raimonda, Vik, Åshild, Harrison, Odile B., Maiden, Martin C. J., Grad, Yonatan H., Koomey, Michael, Casadesús, Josep

Journal:

Year:

2019

File:

PDF, 2.76 MB

2019

52

Phosphatidylserine synthetase regulates cellular homeostasis through distinct metabolic mechanisms

Yang, Xiao, Liang, Jingjing, Ding, Long, Li, Xia, Lam, Sin-Man, Shui, Guanghou, Ding, Mei, Huang, Xun, Teleman, Aurelio A.

Journal:

Year:

2019

File:

PDF, 18.67 MB

2019

53

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

de Castro, Patrícia Alves, Colabardini, Ana Cristina, Manfiolli, Adriana Oliveira, Chiaratto, Jéssica, Silva, Lilian Pereira, Mattos, Eliciane Cevolani, Palmisano, Giuseppe, Almeida, Fausto, Persinoti

Journal:

Year:

2019

File:

PDF, 12.57 MB

2019

54

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4

Garrett, Andrew M., Bosch, Peter J., Steffen, David M., Fuller, Leah C., Marcucci, Charles G., Koch, Alexis A., Bais, Preeti, Weiner, Joshua A., Burgess, Robert W., Garcia-Bassets, Ivan

Journal:

Year:

2019

File:

PDF, 14.97 MB

2019

55

Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII

Pinar, Mario, Arias-Palomo, Ernesto, de los Ríos, Vivian, Arst, Herbert N., Peñalva, Miguel A., Idnurm, Alexander

Journal:

Year:

2019

File:

PDF, 8.33 MB

2019

56

BLISTER-regulated vegetative growth is dependent on the protein kinase domain of ER stress modulator IRE1A in Arabidopsis thaliana

Hong, Zheng-Hui, Qing, Tao, Schubert, Daniel, Kleinmanns, Julia Anna, Liu, Jian-Xiang, Qu, Li-Jia

Journal:

Year:

2019

File:

PDF, 13.89 MB

2019

57

Cell elimination strategies upon identity switch via modulation of apterous in Drosophila wing disc

Klipa, Olga, Hamaratoglu, Fisun, Schweisguth, François

Journal:

Year:

2019

File:

PDF, 14.27 MB

2019

58

Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude

Fustier, Margaux-Alison, Martínez-Ainsworth, Natalia E., Aguirre-Liguori, Jonás A., Venon, Anthony, Corti, Hélène, Rousselet, Agnès, Dumas, Fabrice, Dittberner, Hannes, Camarena, María G., Grimanelli,

Journal:

Year:

2019

File:

PDF, 4.97 MB

2019

59

A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays

Guiseppi, Annick, Vicente, Juan Jesus, Herrou, Julien, Byrne, Deborah, Barneoud, Aurelie, Moine, Audrey, Espinosa, Leon, Basse, Marie-Jeanne, Molle, Virginie, Mignot, TÃ¢m, Roche, Philippe, Mauriello,

Journal:

Year:

2019

File:

PDF, 2.82 MB

2019