Volume 16; Issue 3

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PLoS Genetics
Volume 16; Issue 3

PLoS Genetics

Volume 16; Issue 3

1

Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data

Howey, Richard, Shin, So-Youn, Relton, Caroline, Davey Smith, George, Cordell, Heather J., Williams, Scott M.

Journal:

Year:

2020

File:

PDF, 6.16 MB

2020

2

Correction: Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Waldron, Fergal M., Stone, Graham N., Obbard, Darren J.

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Year:

2020

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PDF, 208 KB

2020

3

The SNAP hypothesis: Chromosomal rearrangements could emerge from positive Selection during Niche Adaptation

Brandis, Gerrit, Hughes, Diarmaid, Rocha, Eduardo P. C.

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Year:

2020

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PDF, 1.60 MB

2020

4

Disentangling group specific QTL allele effects from genetic background epistasis using admixed individuals in GWAS: An application to maize flowering

Rio, Simon, Mary-Huard, Tristan, Moreau, Laurence, Bauland, Cyril, Palaffre, Carine, Madur, Delphine, Combes, ValÃ©rie, Charcosset, Alain, Springer, Nathan M.

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Year:

2020

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PDF, 3.76 MB

2020

5

Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria

Jeong, Dae-Eun, Lee, Yujin, Ham, Seokjin, Lee, Dongyeop, Kwon, Sujeong, Park, Hae-Eun H., Hwang, Sun-Young, Yoo, Joo-Yeon, Roh, Tae-Young, Lee, Seung-Jae V., Garsin, Danielle A.

Journal:

Year:

2020

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PDF, 3.63 MB

2020

6

The Lid/KDM5 histone demethylase complex activates a critical effector of the oocyte-to-zygote transition

Torres-Campana, Daniela, Kimura, Shuhei, Orsi, Guillermo A., Horard, BÃ©atrice, Benoit, GÃ©rard, Loppin, Benjamin, Bosco, Giovanni

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Year:

2020

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PDF, 2.94 MB

2020

7

FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas

Zhao, Qin, Li, Shufen, Shao, Shangjin, Wang, Zhengmao, Pan, Junmin, Dutcher, Susan K.

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Year:

2020

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PDF, 5.75 MB

2020

8

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

Ferreira, Nicola, Andoniou, Christopher E., Perks, Kara L., Ermer, Judith A., Rudler, Danielle L., Rossetti, Giulia, Periyakaruppiah, Ambika, Wong, Jamie K. Y., Rackham, Oliver, Noakes, Peter G., Degl

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Year:

2020

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PDF, 2.86 MB

2020

9

The emerging role of transcriptional regulation in the oocyte-to-zygote transition

Navarro-Costa, Paulo, Martinho, Rui GonÃ§alo, Bosco, Giovanni

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Year:

2020

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PDF, 495 KB

2020

10

Histone H4 dosage modulates DNA damage response in the pathogenic yeast Candida glabrata via homologous recombination pathway

Kumar, Kundan, Moirangthem, Romila, Kaur, Rupinder, Freitag, Michael

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Year:

2020

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PDF, 3.81 MB

2020

11

Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency

Sanchez, Anthony, de Vivo, Angelo, Tonzi, Peter, Kim, Jeonghyeon, Huang, Tony T., Kee, Younghoon, Eng, Charis

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Year:

2020

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PDF, 8.08 MB

2020

12

Tracking human population structure through time from whole genome sequences

Wang, Ke, Mathieson, Iain, OâConnell, Jared, Schiffels, Stephan, Schierup, Mikkel H.

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Year:

2020

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PDF, 4.05 MB

2020

13

The influence of rare variants in circulating metabolic biomarkers

Riveros-Mckay, Fernando, Oliver-Williams, Clare, Karthikeyan, Savita, Walter, Klaudia, Kundu, Kousik, Ouwehand, Willem H., Roberts, David, Di Angelantonio, Emanuele, Soranzo, Nicole, Danesh, John, Whe

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2020

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PDF, 2.07 MB

2020

14

Recessive missense LAMP3 variant associated with defect in lamellar body biogenesis and fatal neonatal interstitial lung disease in dogs

Dillard, Kati J., Ochs, Matthias, Niskanen, Julia E., Arumilli, Meharji, Donner, Jonas, KyÃ¶stilÃ¤, Kaisa, HytÃ¶nen, Marjo K., Anttila, Marjukka, Lohi, Hannes, Barsh, Gregory S.

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Year:

2020

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PDF, 14.18 MB

2020

15

Global mistranslation increases cell survival under stress in Escherichia coli

Samhita, Laasya, Raval, Parth K., Agashe, Deepa, Matic, Ivan

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Year:

2020

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PDF, 2.50 MB

2020

16

A putative silencer variant in a spontaneous canine model of retinitis pigmentosa

Kaukonen, Maria, Quintero, Ileana B., Mukarram, Abdul Kadir, HytÃ¶nen, Marjo K., Holopainen, Saila, WickstrÃ¶m, Kaisa, KyÃ¶stilÃ¤, Kaisa, Arumilli, Meharji, JalomÃ¤ki, Sari, Daub, Carsten O., Kere, Ju

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Year:

2020

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PDF, 3.65 MB

2020

17

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

Fang, Yufeng, Coelho, Marco A., Shu, Haidong, Schotanus, Klaas, Thimmappa, Bhagya C., Yadav, Vikas, Chen, Han, Malc, Ewa P., Wang, Jeremy, Mieczkowski, Piotr A., Kronmiller, Brent, Tyler, Brett M., Sa

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Year:

2020

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PDF, 13.91 MB

2020

18

What is ancestry?

Mathieson, Iain, Scally, Aylwyn, Flint, Jonathan

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Year:

2020

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PDF, 1.06 MB

2020

19

Drosophila insulin-like peptide 2 mediates dietary regulation of sleep intensity

Brown, Elizabeth B., Shah, Kreesha D., Faville, Richard, Kottler, Benjamin, Keene, Alex C., Pletcher, Scott D.

Journal:

Year:

2020

Language:

english

File:

PDF, 5.60 MB

english, 2020

20

A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters

Fasulo, Barbara, Meccariello, Angela, Morgan, Maya, Borufka, Carl, Papathanos, Philippos Aris, Windbichler, Nikolai, Malik, Harmit S.

Journal:

Year:

2020

Language:

english

File:

PDF, 3.97 MB

english, 2020

21

A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

Venkei, Zsolt G., Choi, Charlotte, Feng, Suhua, Chen, Cuie, Jacobsen, Steven E., Kim, John K., Yamashita, Yukiko M., Bosco, Giovanni

Journal:

Year:

2020

Language:

english

File:

PDF, 18.73 MB

english, 2020

22

Non-lethal exposure to H2O2 boosts bacterial survival and evolvability against oxidative stress

RodrÃguez-Rojas, Alexandro, Kim, Joshua Jay, Johnston, Paul, Makarova, Olga, Eravci, Murat, Weise, Christoph, Hengge, Regine, Rolff, Jens, Matic, Ivan

Journal:

Year:

2020

Language:

english

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PDF, 13.25 MB

english, 2020

23

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels

Morgan, Michael D., Patin, Etienne, Jagla, Bernd, Hasan, Milena, Quintana-Murci, LluÃs, Marioni, John C., Snyder, Michael

Journal:

Year:

2020

Language:

english

File:

PDF, 2.55 MB

english, 2020

24

The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis

SchÃ¤fer, Heinrich, Beckert, Bertrand, Frese, Christian K., Steinchen, Wieland, Nuss, Aaron M., Beckstette, Michael, Hantke, Ingo, Driller, Kristina, SudzinovÃ¡, Petra, KrÃ¡snÃ½, Libor, Kaever, Volkha

Journal:

Year:

2020

Language:

english

File:

PDF, 3.15 MB

english, 2020

25

Cell cycle transcriptomics of Capsaspora provides insights into the evolution of cyclin-CDK machinery

PÃ©rez-Posada, Alberto, Dudin, Omaya, OcaÃ±a-PallarÃ¨s, Eduard, Ruiz-Trillo, IÃ±aki, Ondracka, Andrej, Heitman, Joseph

Journal:

Year:

2020

Language:

english

File:

PDF, 4.62 MB

english, 2020

26

A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions

Coste de Bagneaux, Pierre, von Elsner, Leonie, Bierhals, Tatjana, Campiglio, Marta, Johannsen, Jessika, Obermair, Gerald J., Hempel, Maja, Flucher, Bernhard E., Kutsche, Kerstin, Helbig, Ingo

Journal:

Year:

2020

Language:

english

File:

PDF, 15.20 MB

english, 2020

27

Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation

Wu, Daniel C., Zamorano-SÃ¡nchez, David, Pagliai, Fernando A., Park, Jin Hwan, Floyd, Kyle A., Lee, Calvin K., Kitts, Giordan, Rose, Christopher B., Bilotta, Eric M., Wong, Gerard C. L., Yildiz, Fitna

Journal:

Year:

2020

Language:

english

File:

PDF, 17.75 MB

english, 2020

28

Transcriptional regulation of genes bearing intronic heterochromatin in the rice genome

Espinas, Nino A., Tu, Le Ngoc, Furci, Leonardo, Shimajiri, Yasuka, Harukawa, Yoshiko, Miura, Saori, Takuno, Shohei, Saze, Hidetoshi, Mittelsten Scheid, Ortrun

Journal:

Year:

2020

Language:

english

File:

PDF, 7.67 MB

english, 2020

29

RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination

Victorino, Jose F., Fox, Melanie J., Smith-Kinnaman, Whitney R., Peck Justice, Sarah A., Burriss, Katlyn H., Boyd, Asha K., Zimmerly, Megan A., Chan, Rachel R., Hunter, Gerald O., Liu, Yunlong, Mosley

Journal:

Year:

2020

Language:

english

File:

PDF, 8.34 MB

english, 2020

30

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

Hohl, Marcel, Mojumdar, Aditya, Hailemariam, Sarem, Kuryavyi, Vitaly, Ghisays, Fiorella, Sorenson, Kyle, Chang, Matthew, Taylor, Barry S., Patel, Dinshaw J., Burgers, Peter M., Cobb, Jennifer A., Petr

Journal:

Year:

2020

Language:

english

File:

PDF, 9.89 MB

english, 2020

31

ESCRTing proteasomes to the lysosome

Segev, Nava, Hopper, Anita K.

Journal:

Year:

2020

Language:

english

File:

PDF, 425 KB

english, 2020

32

Autophagy compensates for defects in mitochondrial dynamics

Haeussler, Simon, KÃ¶hler, Fabian, Witting, Michael, Premm, Madeleine F., Rolland, StÃ©phane G., Fischer, Christian, Chauve, Laetitia, Casanueva, Olivia, Conradt, Barbara, Copenhaver, Gregory P.

Journal:

Year:

2020

Language:

english

File:

PDF, 11.85 MB

english, 2020

33

A Snf1-related nutrient-responsive kinase antagonizes endocytosis in yeast

Tumolo, Jessica M., Hepowit, Nathaniel L., Joshi, Samika S., MacGurn, Jason A., Copenhaver, Gregory P.

Journal:

Year:

2020

Language:

english

File:

PDF, 15.67 MB

english, 2020

34

Correction: Mck1 kinase is a new player in the DNA damage checkpoint pathway

Journal:

Year:

2020

Language:

english

File:

PDF, 200 KB

english, 2020

35

GLP-1 NotchâLAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Chen, Jian, Mohammad, Ariz, Pazdernik, Nanette, Huang, Huiyan, Bowman, Beth, Tycksen, Eric, Schedl, Tim, Greenstein, David

Journal:

Year:

2020

Language:

english

File:

PDF, 5.33 MB

english, 2020

36

E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish

Xie, Haibo, Kang, Yunsi, Wang, Shuo, Zheng, Pengfei, Chen, Zhe, Roy, Sudipto, Zhao, Chengtian, OâBryan, Moira K.

Journal:

Year:

2020

Language:

english

File:

PDF, 22.32 MB

english, 2020

37

Girdin is a component of the lateral polarity protein network restricting cell dissemination

Biehler, CornÃ©lia, Wang, Li-Ting, SÃ©vigny, Myriam, JettÃ©, Alexandra, Gamblin, ClÃ©mence L., Catterall, Rachel, Houssin, Elise, McCaffrey, Luke, Laprise, Patrick, Peifer, Mark

Journal:

Year:

2020

Language:

english

File:

PDF, 14.65 MB

english, 2020

38

WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

Kabrawala, Shail, Zimmer, Margaret D., Campellone, Kenneth G., Fritz-Laylin, Lillian

Journal:

Year:

2020

Language:

english

File:

PDF, 15.09 MB

english, 2020

39

The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion

Deng, Ting, Stempor, Przemyslaw, Appert, Alex, Daube, Michael, Ahringer, Julie, Hajnal, Alex, Lattmann, Evelyn, Sherwood, David R.

Journal:

Year:

2020

File:

PDF, 17.06 MB

2020

40

Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia

Yoke, Hiroshi, Ueno, Hironori, Narita, Akihiro, Sakai, Takafumi, Horiuchi, Kahoru, Shingyoji, Chikako, Hamada, Hiroshi, Shinohara, Kyosuke, Omran, Heymut

Journal:

Year:

2020

File:

PDF, 15.13 MB

2020

41

Light affects tissue patterning of the hypocotyl in the shade-avoidance response

Botterweg-Paredes, Esther, Blaakmeer, Anko, Hong, Shin-Young, Sun, Bin, Mineri, Lorenzo, Kruusvee, Valdeko, Xie, Yakun, Straub, Daniel, MÃ©nard, Delphine, Pesquet, Edouard, Wenkel, Stephan, Qu, Li-Jia

Journal:

Year:

2020

File:

PDF, 8.61 MB

2020

42

pH-dependent activation of cytokinesis modulates Escherichia coli cell size

Mueller, Elizabeth A., Westfall, Corey S., Levin, Petra Anne, Jonas, Kristina

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Year:

2020

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PDF, 7.20 MB

2020

43

Evidence of defined temporal expression patterns that lead aÂ gram-negative cell out of dormancy

Ashok, Nandhini, Bauer, Carl E., NÃºÃ±ez, Cinthia

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Year:

2020

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PDF, 6.49 MB

2020

44

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin

Lee, Yuh Chwen G., Ogiyama, Yuki, Martins, Nuno M. C., Beliveau, Brian J., Acevedo, David, Wu, C.-ting, Cavalli, Giacomo, Karpen, Gary H., Bosco, Giovanni

Journal:

Year:

2020

File:

PDF, 4.70 MB

2020

45

Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in mice

Hamada, Norio, Hamazaki, Nobuhiko, Shimamoto, So, Hikabe, Orie, Nagamatsu, Go, Takada, Yuki, Kato, Kiyoko, Hayashi, Katsuhiko, Cohen, Paula E.

Journal:

Year:

2020

Language:

english

File:

PDF, 11.30 MB

english, 2020

46

Pleiotropy facilitates local adaptation to distant optima in common ragweed (Ambrosia artemisiifolia)

HÃ¤mÃ¤lÃ¤, Tuomas, Gorton, Amanda J., Moeller, David A., Tiffin, Peter, de Meaux, Juliette

Journal:

Year:

2020

Language:

english

File:

PDF, 4.63 MB

english, 2020

47

DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs

Dai, James Y., Wang, Xiaoyu, Wang, Bo, Sun, Wei, Jordahl, Kristina M., Kolb, Suzanne, Nyame, Yaw A., Wright, Jonathan L., Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L., Schumacher, Fredrick

Journal:

Year:

2020

Language:

english

File:

PDF, 6.08 MB

english, 2020

48

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

Hu, Yao, Graff, Mariaelisa, Haessler, Jeffrey, Buyske, Steven, Bien, Stephanie A., Tao, Ran, Highland, Heather M., Nishimura, Katherine K., Zubair, Niha, Lu, Yingchang, Verbanck, Marie, Hilliard, Aust

Journal:

Year:

2020

Language:

english

File:

PDF, 1.99 MB

english, 2020

49

The conserved regulatory basis of mRNA contributions to the early Drosophila embryo differs between the maternal and zygotic genomes

Omura, Charles S., Lott, Susan E., Harrison, Melissa M.

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Year:

2020

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PDF, 3.21 MB

2020

50

Correction:Â Co-Evolution of Mitochondrial tRNA Import and Codon Usage Determines Translational Efficiency in the Green Alga Chlamydomonas

Salinas, Thalia, Duby, FrancÃ©line, Larosa, VÃ©ronique, Coosemans, Nadine, Bonnefoy, Nathalie, Motte, Patrick, MarÃ©chal-Drouard, Laurence, Remacle, Claire

Journal:

Year:

2020

File:

PDF, 700 KB

2020